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The map label for this gene is coq7 [H]

Identifier: 83310631

GI number: 83310631

Start: 1662424

End: 1662981

Strand: Reverse

Name: coq7 [H]

Synonym: amb1532

Alternate gene names: 83310631

Gene position: 1662981-1662424 (Counterclockwise)

Preceding gene: 83310632

Following gene: 83310611

Centisome position: 33.48

GC content: 69.89

Gene sequence:

>558_bases
ATGAGAAAGACCGGCGACGACGCCATTCCCGGCGACCTCGACCATGCCGGCCTGATCGACCGCTTCCTGCGGGTCAATCA
GGCGGGAGAGCTGGGCGCCGTGCGCATCTACCAGGGGCAGCGGGCCATCCTCGGCCGCAAGGGCGGCCCCACCGCCCCCC
TGCTCAAGCGCATGGCCGAGCAGGAGCAGGAGCATCTCGATACCTTCAGCCACCTGATCGGCGAGCGCCGCACCCGCCCC
ACCGTGCTGTCGCCGCTGTGGCATCTGGCCGGCTTCGCCCTGGGGGCCGGCACCGCCTTGCTGGGCGAAAAGGCCGCCAT
GGCCTGCACCGTGGCGGTGGAGGAGACCATCGACGAGCATTACGCCCGGCAGGCGGAACAACTGGGCGAGGACGAAGCGG
CGCTGAAGGACACCATCCGCAAGTTCCGCGAGGACGAGATCGAACACCGCGACATCGGCTTGGCCCACGGCGCCGAGCAG
GCCCCGGCCTATCCCCTGCTGTCCTCGGCCATCAAGGGCGGCTGCCGCCTGGCCATCTGGCTCAGCGAGCGGATCTGA

Upstream 100 bases:

>100_bases
GGTCGTTCCACGGCATCACCATGGCCGCCCTCAACGTGCCGTTCTCGGCCCTGTTCGGCCTTGCGGTGCTGTGGGCGGCA
CGGCGTTCGGAGGGCTCCGC

Downstream 100 bases:

>100_bases
CCCAGCCCGCCGGTTCGATGCGGGTGATCAGGCAGTTGCGCGACGGCATTTCGGGCAACATCTCCACCGGCCAGCCCAGA
TGGTGCAGCGCCAGCGAGCG

Product: ubiquinone biosynthesis protein COQ7

Products: NA

Alternate protein names: 5-demethoxyubiquinone hydroxylase; DMQ hydroxylase [H]

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MRKTGDDAIPGDLDHAGLIDRFLRVNQAGELGAVRIYQGQRAILGRKGGPTAPLLKRMAEQEQEHLDTFSHLIGERRTRP
TVLSPLWHLAGFALGAGTALLGEKAAMACTVAVEETIDEHYARQAEQLGEDEAALKDTIRKFREDEIEHRDIGLAHGAEQ
APAYPLLSSAIKGGCRLAIWLSERI

Sequences:

>Translated_185_residues
MRKTGDDAIPGDLDHAGLIDRFLRVNQAGELGAVRIYQGQRAILGRKGGPTAPLLKRMAEQEQEHLDTFSHLIGERRTRP
TVLSPLWHLAGFALGAGTALLGEKAAMACTVAVEETIDEHYARQAEQLGEDEAALKDTIRKFREDEIEHRDIGLAHGAEQ
APAYPLLSSAIKGGCRLAIWLSERI
>Mature_185_residues
MRKTGDDAIPGDLDHAGLIDRFLRVNQAGELGAVRIYQGQRAILGRKGGPTAPLLKRMAEQEQEHLDTFSHLIGERRTRP
TVLSPLWHLAGFALGAGTALLGEKAAMACTVAVEETIDEHYARQAEQLGEDEAALKDTIRKFREDEIEHRDIGLAHGAEQ
APAYPLLSSAIKGGCRLAIWLSERI

Specific function: Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol [H]

COG id: COG2941

COG function: function code H; Ubiquinone biosynthesis protein COQ7

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the COQ7 family [H]

Homologues:

Organism=Homo sapiens, GI300244542, Length=171, Percent_Identity=54.9707602339181, Blast_Score=188, Evalue=2e-48,
Organism=Homo sapiens, GI25453484, Length=171, Percent_Identity=54.9707602339181, Blast_Score=187, Evalue=5e-48,
Organism=Caenorhabditis elegans, GI17552756, Length=172, Percent_Identity=43.0232558139535, Blast_Score=142, Evalue=7e-35,
Organism=Saccharomyces cerevisiae, GI6324699, Length=185, Percent_Identity=43.2432432432432, Blast_Score=153, Evalue=1e-38,
Organism=Drosophila melanogaster, GI24640215, Length=171, Percent_Identity=54.3859649122807, Blast_Score=179, Evalue=1e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012347
- InterPro:   IPR009078
- InterPro:   IPR011566 [H]

Pfam domain/function: PF03232 COQ7 [H]

EC number: 1.14.13.-

Molecular weight: Translated: 20254; Mature: 20254

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKTGDDAIPGDLDHAGLIDRFLRVNQAGELGAVRIYQGQRAILGRKGGPTAPLLKRMAE
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCHHHHCCCCCCHHHHHHHHHH
QEQEHLDTFSHLIGERRTRPTVLSPLWHLAGFALGAGTALLGEKAAMACTVAVEETIDEH
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
YARQAEQLGEDEAALKDTIRKFREDEIEHRDIGLAHGAEQAPAYPLLSSAIKGGCRLAIW
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCEEEEE
LSERI
ECCCC
>Mature Secondary Structure
MRKTGDDAIPGDLDHAGLIDRFLRVNQAGELGAVRIYQGQRAILGRKGGPTAPLLKRMAE
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCHHHHCCCCCCHHHHHHHHHH
QEQEHLDTFSHLIGERRTRPTVLSPLWHLAGFALGAGTALLGEKAAMACTVAVEETIDEH
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
YARQAEQLGEDEAALKDTIRKFREDEIEHRDIGLAHGAEQAPAYPLLSSAIKGGCRLAIW
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCEEEEE
LSERI
ECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 14500782 [H]