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The map label for this gene is xdhB [H]

Identifier: 83310583

GI number: 83310583

Start: 1623385

End: 1624227

Strand: Reverse

Name: xdhB [H]

Synonym: amb1484

Alternate gene names: 83310583

Gene position: 1624227-1623385 (Counterclockwise)

Preceding gene: 83310584

Following gene: 83310582

Centisome position: 32.7

GC content: 71.53

Gene sequence:

>843_bases
ATGCGCTGCGACTATCCAACCACCGTGAACGAGGCGCTGGCGCTGTTGGCCGCCGCGCCCGACAGCGTCCTGGTCGCCGG
CTGCACCGATTTCTTTCCCGCCCAGGGCCTAGCCCCGATCACCCGGCCGATCATCGACCTGTCGGCCATCGCCGAGGCCC
GGGGCATCGCCGCCGGGGCCGATGGCTGGCGCTTCGGCGCGCTGACTACCTGGAGCGATATCGCCACGGCCGACCTGCCC
GCCCGCTTTCGCGGCCTGCAGCAGGCGGCGCGGCAGGTGGGCGCCCTTCAGATCCAGAATGTCGGCACCATCGGCGGCAA
TCTGTGCAACGCCTCGCCCGCCGCCGACGGCGTGCCGCCGCTGCTGTGCCTGGACGCCTCGGTGGAGCTGGCTTCGGCGG
AGGGCACCCGCAAGGTGCCGCTGGACCGCTTCATCCTGGGCAACCGCAAGACCGAACGCCGCCCCGACGAGATGGTCACC
GCCATCCTGATTCCCGACGGCGGCGCCAAGGCCGCCTCCGCCTTCCTGAAGCTGGGCTCGCGCACCTCTTTGGTGATTTC
CATCGCCATGGTCTCGGTGCTGCTGGAGGCCGATGGCGCGGGCAAGGTGGCCCGGGCCGCCGTCGCGGTGGGCGCCTGTT
CGGTGGTCGCCAAGCGCCTGGAGGCGCTGGAGGCCGATCTGCGGGGCCAGCCCGTCTCGCCCGGCCTGGCCGATCTGGTC
ACCCCCGCCCATCTGTCGCCGCTCAGCCCCATCCGGGATCTGCGCGGCACGCCGGAATATCGCCTCGACGTGGCGCTGAC
CATGATCCGTCGCGGGCTTGCCGAAGTCGGAGGCCTTGTCTGA

Upstream 100 bases:

>100_bases
CCACCCTTGACACTGCCGCCCCCTTTTTCGTTAACATCATATGTGTACGAACAATACGGCAGAGACCCGCCGTAGGAGCC
ACGGGAAGGAAGGCAGAACC

Downstream 100 bases:

>100_bases
TGAAGCGCCAGACCCTCTCCATCAACGGGACCAGCCACAGCCTGGAGGTGCCGCCCATGCGCCGCCTCTCCAAGGTCCTG
CGCGAAGACCTGGGCCTGCG

Product: aerobic-type carbon monoxide dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MRCDYPTTVNEALALLAAAPDSVLVAGCTDFFPAQGLAPITRPIIDLSAIAEARGIAAGADGWRFGALTTWSDIATADLP
ARFRGLQQAARQVGALQIQNVGTIGGNLCNASPAADGVPPLLCLDASVELASAEGTRKVPLDRFILGNRKTERRPDEMVT
AILIPDGGAKAASAFLKLGSRTSLVISIAMVSVLLEADGAGKVARAAVAVGACSVVAKRLEALEADLRGQPVSPGLADLV
TPAHLSPLSPIRDLRGTPEYRLDVALTMIRRGLAEVGGLV

Sequences:

>Translated_280_residues
MRCDYPTTVNEALALLAAAPDSVLVAGCTDFFPAQGLAPITRPIIDLSAIAEARGIAAGADGWRFGALTTWSDIATADLP
ARFRGLQQAARQVGALQIQNVGTIGGNLCNASPAADGVPPLLCLDASVELASAEGTRKVPLDRFILGNRKTERRPDEMVT
AILIPDGGAKAASAFLKLGSRTSLVISIAMVSVLLEADGAGKVARAAVAVGACSVVAKRLEALEADLRGQPVSPGLADLV
TPAHLSPLSPIRDLRGTPEYRLDVALTMIRRGLAEVGGLV
>Mature_280_residues
MRCDYPTTVNEALALLAAAPDSVLVAGCTDFFPAQGLAPITRPIIDLSAIAEARGIAAGADGWRFGALTTWSDIATADLP
ARFRGLQQAARQVGALQIQNVGTIGGNLCNASPAADGVPPLLCLDASVELASAEGTRKVPLDRFILGNRKTERRPDEMVT
AILIPDGGAKAASAFLKLGSRTSLVISIAMVSVLLEADGAGKVARAAVAVGACSVVAKRLEALEADLRGQPVSPGLADLV
TPAHLSPLSPIRDLRGTPEYRLDVALTMIRRGLAEVGGLV

Specific function: Presumed to be a dehydrogenase, but possibly an oxidase. Participates in limited purine salvage (requires aspartate) but does not support aerobic growth on purines as the sole carbon source (purine catabolism) [H]

COG id: COG1319

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=274, Percent_Identity=29.9270072992701, Blast_Score=81, Evalue=9e-16,
Organism=Escherichia coli, GI1789231, Length=276, Percent_Identity=30.4347826086957, Blast_Score=110, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005107
- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR002346 [H]

Pfam domain/function: PF03450 CO_deh_flav_C; PF00941 FAD_binding_5 [H]

EC number: =1.17.1.4 [H]

Molecular weight: Translated: 28905; Mature: 28905

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRCDYPTTVNEALALLAAAPDSVLVAGCTDFFPAQGLAPITRPIIDLSAIAEARGIAAGA
CCCCCCCCHHHHHHHHHCCCCCEEEECCHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCC
DGWRFGALTTWSDIATADLPARFRGLQQAARQVGALQIQNVGTIGGNLCNASPAADGVPP
CCCEECCCCCHHHHHHCCCCHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCCCCCC
LLCLDASVELASAEGTRKVPLDRFILGNRKTERRPDEMVTAILIPDGGAKAASAFLKLGS
EEEECCCEEEECCCCCCCCCHHHHHHCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHCCC
RTSLVISIAMVSVLLEADGAGKVARAAVAVGACSVVAKRLEALEADLRGQPVSPGLADLV
CHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHC
TPAHLSPLSPIRDLRGTPEYRLDVALTMIRRGLAEVGGLV
CCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRCDYPTTVNEALALLAAAPDSVLVAGCTDFFPAQGLAPITRPIIDLSAIAEARGIAAGA
CCCCCCCCHHHHHHHHHCCCCCEEEECCHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCC
DGWRFGALTTWSDIATADLPARFRGLQQAARQVGALQIQNVGTIGGNLCNASPAADGVPP
CCCEECCCCCHHHHHHCCCCHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCCCCCC
LLCLDASVELASAEGTRKVPLDRFILGNRKTERRPDEMVTAILIPDGGAKAASAFLKLGS
EEEECCCEEEECCCCCCCCCHHHHHHCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHCCC
RTSLVISIAMVSVLLEADGAGKVARAAVAVGACSVVAKRLEALEADLRGQPVSPGLADLV
CHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHC
TPAHLSPLSPIRDLRGTPEYRLDVALTMIRRGLAEVGGLV
CCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]