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The map label for this gene is cat1 [H]

Identifier: 83310482

GI number: 83310482

Start: 1500692

End: 1502326

Strand: Reverse

Name: cat1 [H]

Synonym: amb1383

Alternate gene names: 83310482

Gene position: 1502326-1500692 (Counterclockwise)

Preceding gene: 83310483

Following gene: 83310481

Centisome position: 30.25

GC content: 65.02

Gene sequence:

>1635_bases
ATGCGGCCCTGCGCCTCGGACATGCATGGGGCCGTGCAAACTCTGCATTTCGCCTGCCCCCTCCCCCGTCCGCTACCGTT
CTGCCCGAGCGCGCCGAGTTGCGCCATCTGGGATAAGGAAACGGGCATGTATCGCGACAGAATCGGATTGACCTCCCTGT
GGGGCAAGGTGGTGGGCGCCGAAGAGGCGGCCATGCACATCAAGGACGGCATGGTGGTGGGCATGAGCGGCTTCACCCGG
GCGGGCGACGCCAAGGTGGTGCCCATGGCCCTGGCCGAGCGGGCCACCGAGGAGAAACTGAAAATCACCCTGATGACGGG
GGCCAGCCTGGGCAGCGACATCGACAAGACCCTGGCCCAGGCCGGCTGTCTGTCGCGCCGCATTCCCTTCCAGGCCGATC
CCACCCTGCGCAAGTCCATCAATGCCGGCGAGGTGATGTTCGTCGACCAGCACCTGTCGGAGACGGTGGAGATGCTGCGT
TCGCGCCAGATGGCGCCCATCGACGTGGCTGTCATCGAGGCGGTGGCCATCACGCCGGAAGGCGGCATCATCCCCACCAC
CTCCATCGGCAATTCCGCCAGCTTCGCCATCCTGGCCGAGAAGATCATCGTCGAGATCAACCTGCATCAGAGCCTGGACC
TGATCGGCCTGCACGACGTCTATATCCCGACGCGACGTCCCCACCGCGAGCCGATTCCCCTGGTCACGCCGTCGGACCGC
ATCGGCCTGCCCTACATTCCGGTCGATCCCTCCAAGATCGCCGCCATCGTCATCACCGAGAAAAACGACAGCTCGGCCAA
CATCGCCCCGGCCGATGCCGAGACCAAGGCCATCGCCGACCACCTGATCGATTTCTTCCGCCAGGAGGTCAGGAAGGGGC
GCATCGGCACCTCGCTGCTGCCGCTGCAGGCAGGCATCGGCTCCATCGCCAACGCCGTCCTGGGCGGCTTCATCGATTCG
CCGTTCCACGACCTTTCCATGTATTCCGAGGTGTTGCAGGACTGCACCTTCGACCTGTTCGATTCCGGCAAGCTGAAATT
CGCCTCGGGCTCGTCCATCACCCTCTCCGGCCCCCGGGGCAAGGAGGTGTTCGGCAATATCGGCAAGTACAAGGACCGCC
TCGTCCTGCGCCCGCAGGAGGTCAGCAATCACCCCGAGGTCATCCGCCGCCTGGGTCTGATCTGCATCAACACCGCGCTG
GAGGCCGATATCTACGGCAACGTCAACTCGACCCACGTCAACGCCTCCATGATGATGAACGGCATCGGCGGCTCGGGCGA
TTTCGCCCGCAACGCCTATCTCTCGGTGTTCGTCACCAAGTCGATGGCCAAGGACGGCCGCATCTCCTCCATCGTCCCCA
TGGTCACCCATGTGGATCACTGCGAGCACGACGTGGACATCATCGTCACCGAGCGCGGACTGGCCGATCTGCGCGGACTG
GCGCCGCGCGAGCGGGCCAATCTGATGATCGAGCACTGCATGCACCCCGACTACCGGGATCTGGCGCGGGACTACCTCAA
GGACGCCCTGGGCCGGGGCGGCCACACGCCCCATGTCATGGAGCGCGCCTTCGAATGGCATCTGGCCTTCCAGCGCACCG
GCTCCATGCTGCCCCTGGCCAAGGCGGCGGAGTAG

Upstream 100 bases:

>100_bases
CCAGTCGGCTGGAGTTCTTCGCATGTCCGATTCGGATGAAGTACGAAGAACCCTAGCCGTAAACTATTGCTGAATTATTG
CTGCGGACGTCGCGCAGGGC

Downstream 100 bases:

>100_bases
CGCTCCGCAGGCAGCGGCGGCGCGGCCCTTGGCGGGGTCGCGTCGCCTCCCGCCCGCCCCCACCCCTTCGGACGGCTTCG
GACCTATCCACAAGAATCTT

Product: Acetyl-CoA hydrolase

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 544; Mature: 544

Protein sequence:

>544_residues
MRPCASDMHGAVQTLHFACPLPRPLPFCPSAPSCAIWDKETGMYRDRIGLTSLWGKVVGAEEAAMHIKDGMVVGMSGFTR
AGDAKVVPMALAERATEEKLKITLMTGASLGSDIDKTLAQAGCLSRRIPFQADPTLRKSINAGEVMFVDQHLSETVEMLR
SRQMAPIDVAVIEAVAITPEGGIIPTTSIGNSASFAILAEKIIVEINLHQSLDLIGLHDVYIPTRRPHREPIPLVTPSDR
IGLPYIPVDPSKIAAIVITEKNDSSANIAPADAETKAIADHLIDFFRQEVRKGRIGTSLLPLQAGIGSIANAVLGGFIDS
PFHDLSMYSEVLQDCTFDLFDSGKLKFASGSSITLSGPRGKEVFGNIGKYKDRLVLRPQEVSNHPEVIRRLGLICINTAL
EADIYGNVNSTHVNASMMMNGIGGSGDFARNAYLSVFVTKSMAKDGRISSIVPMVTHVDHCEHDVDIIVTERGLADLRGL
APRERANLMIEHCMHPDYRDLARDYLKDALGRGGHTPHVMERAFEWHLAFQRTGSMLPLAKAAE

Sequences:

>Translated_544_residues
MRPCASDMHGAVQTLHFACPLPRPLPFCPSAPSCAIWDKETGMYRDRIGLTSLWGKVVGAEEAAMHIKDGMVVGMSGFTR
AGDAKVVPMALAERATEEKLKITLMTGASLGSDIDKTLAQAGCLSRRIPFQADPTLRKSINAGEVMFVDQHLSETVEMLR
SRQMAPIDVAVIEAVAITPEGGIIPTTSIGNSASFAILAEKIIVEINLHQSLDLIGLHDVYIPTRRPHREPIPLVTPSDR
IGLPYIPVDPSKIAAIVITEKNDSSANIAPADAETKAIADHLIDFFRQEVRKGRIGTSLLPLQAGIGSIANAVLGGFIDS
PFHDLSMYSEVLQDCTFDLFDSGKLKFASGSSITLSGPRGKEVFGNIGKYKDRLVLRPQEVSNHPEVIRRLGLICINTAL
EADIYGNVNSTHVNASMMMNGIGGSGDFARNAYLSVFVTKSMAKDGRISSIVPMVTHVDHCEHDVDIIVTERGLADLRGL
APRERANLMIEHCMHPDYRDLARDYLKDALGRGGHTPHVMERAFEWHLAFQRTGSMLPLAKAAE
>Mature_544_residues
MRPCASDMHGAVQTLHFACPLPRPLPFCPSAPSCAIWDKETGMYRDRIGLTSLWGKVVGAEEAAMHIKDGMVVGMSGFTR
AGDAKVVPMALAERATEEKLKITLMTGASLGSDIDKTLAQAGCLSRRIPFQADPTLRKSINAGEVMFVDQHLSETVEMLR
SRQMAPIDVAVIEAVAITPEGGIIPTTSIGNSASFAILAEKIIVEINLHQSLDLIGLHDVYIPTRRPHREPIPLVTPSDR
IGLPYIPVDPSKIAAIVITEKNDSSANIAPADAETKAIADHLIDFFRQEVRKGRIGTSLLPLQAGIGSIANAVLGGFIDS
PFHDLSMYSEVLQDCTFDLFDSGKLKFASGSSITLSGPRGKEVFGNIGKYKDRLVLRPQEVSNHPEVIRRLGLICINTAL
EADIYGNVNSTHVNASMMMNGIGGSGDFARNAYLSVFVTKSMAKDGRISSIVPMVTHVDHCEHDVDIIVTERGLADLRGL
APRERANLMIEHCMHPDYRDLARDYLKDALGRGGHTPHVMERAFEWHLAFQRTGSMLPLAKAAE

Specific function: Forms succinyl-CoA from succinate and acetyl-CoA [H]

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=494, Percent_Identity=44.331983805668, Blast_Score=419, Evalue=1e-118,
Organism=Caenorhabditis elegans, GI17538151, Length=215, Percent_Identity=28.3720930232558, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319456, Length=517, Percent_Identity=41.5860735009671, Blast_Score=388, Evalue=1e-108,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702
- InterPro:   IPR006472
- InterPro:   IPR017821 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro; PF04223 CitF [H]

EC number: NA

Molecular weight: Translated: 59142; Mature: 59142

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPCASDMHGAVQTLHFACPLPRPLPFCPSAPSCAIWDKETGMYRDRIGLTSLWGKVVGA
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCHHHHCCHHHHHHHHHCC
EEAAMHIKDGMVVGMSGFTRAGDAKVVPMALAERATEEKLKITLMTGASLGSDIDKTLAQ
HHHHHEECCCEEECCCCCCCCCCCEEEHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHH
AGCLSRRIPFQADPTLRKSINAGEVMFVDQHLSETVEMLRSRQMAPIDVAVIEAVAITPE
HHHHHCCCCCCCCCHHHHCCCCCCEEEEHHHHHHHHHHHHCCCCCCEEHEEEEEEEECCC
GGIIPTTSIGNSASFAILAEKIIVEINLHQSLDLIGLHDVYIPTRRPHREPIPLVTPSDR
CCEEECCCCCCCCHHHEEEEEEEEEEECCCCCCEEEEEEEECCCCCCCCCCCCEECCCCC
IGLPYIPVDPSKIAAIVITEKNDSSANIAPADAETKAIADHLIDFFRQEVRKGRIGTSLL
CCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCH
PLQAGIGSIANAVLGGFIDSPFHDLSMYSEVLQDCTFDLFDSGKLKFASGSSITLSGPRG
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHCCCCCEEEECCCEEEECCCCC
KEVFGNIGKYKDRLVLRPQEVSNHPEVIRRLGLICINTALEADIYGNVNSTHVNASMMMN
HHHHCCCCCCCCEEEECCHHHCCCHHHHHHHHHHHHHHHHHHEECCCCCCCEEEHHHEEE
GIGGSGDFARNAYLSVFVTKSMAKDGRISSIVPMVTHVDHCEHDVDIIVTERGLADLRGL
CCCCCCCCHHCCEEEEEEEHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHCC
APRERANLMIEHCMHPDYRDLARDYLKDALGRGGHTPHVMERAFEWHLAFQRTGSMLPLA
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCC
KAAE
CCCC
>Mature Secondary Structure
MRPCASDMHGAVQTLHFACPLPRPLPFCPSAPSCAIWDKETGMYRDRIGLTSLWGKVVGA
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCHHHHCCHHHHHHHHHCC
EEAAMHIKDGMVVGMSGFTRAGDAKVVPMALAERATEEKLKITLMTGASLGSDIDKTLAQ
HHHHHEECCCEEECCCCCCCCCCCEEEHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHH
AGCLSRRIPFQADPTLRKSINAGEVMFVDQHLSETVEMLRSRQMAPIDVAVIEAVAITPE
HHHHHCCCCCCCCCHHHHCCCCCCEEEEHHHHHHHHHHHHCCCCCCEEHEEEEEEEECCC
GGIIPTTSIGNSASFAILAEKIIVEINLHQSLDLIGLHDVYIPTRRPHREPIPLVTPSDR
CCEEECCCCCCCCHHHEEEEEEEEEEECCCCCCEEEEEEEECCCCCCCCCCCCEECCCCC
IGLPYIPVDPSKIAAIVITEKNDSSANIAPADAETKAIADHLIDFFRQEVRKGRIGTSLL
CCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCH
PLQAGIGSIANAVLGGFIDSPFHDLSMYSEVLQDCTFDLFDSGKLKFASGSSITLSGPRG
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHCCCCCEEEECCCEEEECCCCC
KEVFGNIGKYKDRLVLRPQEVSNHPEVIRRLGLICINTALEADIYGNVNSTHVNASMMMN
HHHHCCCCCCCCEEEECCHHHCCCHHHHHHHHHHHHHHHHHHEECCCCCCCEEEHHHEEE
GIGGSGDFARNAYLSVFVTKSMAKDGRISSIVPMVTHVDHCEHDVDIIVTERGLADLRGL
CCCCCCCCHHCCEEEEEEEHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHCC
APRERANLMIEHCMHPDYRDLARDYLKDALGRGGHTPHVMERAFEWHLAFQRTGSMLPLA
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCC
KAAE
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]