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The map label for this gene is mocR [H]

Identifier: 83310475

GI number: 83310475

Start: 1493034

End: 1494677

Strand: Reverse

Name: mocR [H]

Synonym: amb1376

Alternate gene names: 83310475

Gene position: 1494677-1493034 (Counterclockwise)

Preceding gene: 83310477

Following gene: 83310474

Centisome position: 30.09

GC content: 71.11

Gene sequence:

>1644_bases
GTGCACGACAGGGCCTCGTCGAGAATGGCTGCCATGGCGTCGAAATCGTGGCTGCCCCGCTGGGGCCGCTGGCGGAAGGT
GGTGCGGTCGGTTCTGGCGGACATGGTGGCTCTCCTTTCCTATTCAGATTGGGCGGAAAGTGGCTCCCTGAAAAGATCCA
CTTCTTTTATAATCATGGAGCCACTTCCCGAGAGCGCCATGCCCCCTCCCCTGCCCTTGGCCCTGCCCGACCTTGACGCT
CCGTTGCATCGGCGCCTGTATCTGGCCTTGCGGGACTCCATTTTGGACGGACGGCTGGCGGAAGGTGCCGCCCTGCCGTC
CTCGCGGGGGTTGGCGGCGCAACTGGGCGTGGCCCGCAACACCGTGCTGGCCGCCTATGACCTTTTGGCCGCCGAGGGCT
TTACCGAAGCCCACCGGGGCTCGGCCACCCGGGTCGCCGCCCGCCACCCTCTCGTGGGAGCCGCCCCGGCGGGCGAAGAA
GCCCCGCCGTCGCCCCTGCCGCCCCGCACCCGGGCCTGGGGCGCCGCCCCGCCCATGATCCTGGTGCGCGACCCGTTCCG
GCCCTTCGCCCCCGGCGTGCCCGATCTGGCGGCCTTTCCCCATGCCGAGTGGCGGCGCGTGCTGGGGCGGCTGTGGCGGC
GGCCCCCGCTGGAGCTGATGGGCGGCATCGATCCCCTGGGCCATGCGCCGCTCCGCCATGCCATCGCCGAGCATCTGGGC
CGCAGCCGGGCGGTGCGCTGCGACCCCGCCCAGGTGATGATCATGGGCGGCTCGCAACAGGCCCTGGACCTGGTGGCCCG
CGTCCTGCTGGAACCGGGGGAGGCGGTGCTGGTGGAAGACCCGTGCTATGGCGGGCTGACCGGCGTGCTGCGCGCCGCCG
GAGCCCAGGTCCAGGCGGTTGCCGTGGATGGCCAGGGCTTCGACCCGGAACTGGCGGAACGGCAATGCCCGTCGGCCCGG
CTGACCTTCGTCACGCCGTCGCACCAGTTCCCCACCGGGGCCACCATGCCGCTGTCGCGCCGCCTTGCCCTGATCCATTG
GGCGGAACGGGTGGGCGGCTGGGTCATCGAGGACGACTACGACAGCGACTTCCACCACGCCGGTTCTCCTACCGCCTCGC
TCCAGGGGCTAGACCGGGGCGGCCGCACCCTTTATCTCGGCACCTTCTCGAAAAGCATGTTTCCCGGGCTGCGCCTGGGC
TGGCTGGTGGTGCCACCGCCGCTGCTGCCGGCCTTCGTGGCGGCGCGACGCATCGCCGACATGGCGCCCGCCGGCCTGAC
CCAGGCGGCCATGGCCGCCTTCATGACCGAAGGCCATTTCGGTGCCCATCTGCGGCGCATGCGCACCCTGTACGGCCAGC
GCCGCCGCGCCTTGCTCGACGCCGCCCCCCGTATCCTCGGCCCGAACCTGCCGGTCACCGCCGGAGAGGCGGGGCTGCAC
GCCATCCTTTGGCTGCCCGCGGGATGCGACGATTTCCAGGCGGCCGAGGCGGCCCGCGCCCGGGGACTGGCGCCCTCGCC
GCTGAGCTTTCATCGTGTCACAAAAGGGTGTCCGGGGCTGGTCCTGGGCTATGGCAACCTGGCGGGATCGAGCCTGGAAG
AGGCCCTCCAGCGGCTACGCGAGGCCATCATCACGTTGATTTAA

Upstream 100 bases:

>100_bases
GAGGCGCGAGCCCTGGCCCCCGTGGAACAGCACCCGCTCGCCCATGCGCCAATGGGTGGTCGGTATACTGACCGGTCGGC
CATCATCGACGAAGGCGATG

Downstream 100 bases:

>100_bases
AACGATTAATATTCCTGTCACAAAAGCTTCATGCTTGTGTCCCCGGACTGTAACACAGCGCCGATAGGATGCCGGCCGAG
GGGACTGATGTCTCCCTCGT

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 547; Mature: 547

Protein sequence:

>547_residues
MHDRASSRMAAMASKSWLPRWGRWRKVVRSVLADMVALLSYSDWAESGSLKRSTSFIIMEPLPESAMPPPLPLALPDLDA
PLHRRLYLALRDSILDGRLAEGAALPSSRGLAAQLGVARNTVLAAYDLLAAEGFTEAHRGSATRVAARHPLVGAAPAGEE
APPSPLPPRTRAWGAAPPMILVRDPFRPFAPGVPDLAAFPHAEWRRVLGRLWRRPPLELMGGIDPLGHAPLRHAIAEHLG
RSRAVRCDPAQVMIMGGSQQALDLVARVLLEPGEAVLVEDPCYGGLTGVLRAAGAQVQAVAVDGQGFDPELAERQCPSAR
LTFVTPSHQFPTGATMPLSRRLALIHWAERVGGWVIEDDYDSDFHHAGSPTASLQGLDRGGRTLYLGTFSKSMFPGLRLG
WLVVPPPLLPAFVAARRIADMAPAGLTQAAMAAFMTEGHFGAHLRRMRTLYGQRRRALLDAAPRILGPNLPVTAGEAGLH
AILWLPAGCDDFQAAEAARARGLAPSPLSFHRVTKGCPGLVLGYGNLAGSSLEEALQRLREAIITLI

Sequences:

>Translated_547_residues
MHDRASSRMAAMASKSWLPRWGRWRKVVRSVLADMVALLSYSDWAESGSLKRSTSFIIMEPLPESAMPPPLPLALPDLDA
PLHRRLYLALRDSILDGRLAEGAALPSSRGLAAQLGVARNTVLAAYDLLAAEGFTEAHRGSATRVAARHPLVGAAPAGEE
APPSPLPPRTRAWGAAPPMILVRDPFRPFAPGVPDLAAFPHAEWRRVLGRLWRRPPLELMGGIDPLGHAPLRHAIAEHLG
RSRAVRCDPAQVMIMGGSQQALDLVARVLLEPGEAVLVEDPCYGGLTGVLRAAGAQVQAVAVDGQGFDPELAERQCPSAR
LTFVTPSHQFPTGATMPLSRRLALIHWAERVGGWVIEDDYDSDFHHAGSPTASLQGLDRGGRTLYLGTFSKSMFPGLRLG
WLVVPPPLLPAFVAARRIADMAPAGLTQAAMAAFMTEGHFGAHLRRMRTLYGQRRRALLDAAPRILGPNLPVTAGEAGLH
AILWLPAGCDDFQAAEAARARGLAPSPLSFHRVTKGCPGLVLGYGNLAGSSLEEALQRLREAIITLI
>Mature_547_residues
MHDRASSRMAAMASKSWLPRWGRWRKVVRSVLADMVALLSYSDWAESGSLKRSTSFIIMEPLPESAMPPPLPLALPDLDA
PLHRRLYLALRDSILDGRLAEGAALPSSRGLAAQLGVARNTVLAAYDLLAAEGFTEAHRGSATRVAARHPLVGAAPAGEE
APPSPLPPRTRAWGAAPPMILVRDPFRPFAPGVPDLAAFPHAEWRRVLGRLWRRPPLELMGGIDPLGHAPLRHAIAEHLG
RSRAVRCDPAQVMIMGGSQQALDLVARVLLEPGEAVLVEDPCYGGLTGVLRAAGAQVQAVAVDGQGFDPELAERQCPSAR
LTFVTPSHQFPTGATMPLSRRLALIHWAERVGGWVIEDDYDSDFHHAGSPTASLQGLDRGGRTLYLGTFSKSMFPGLRLG
WLVVPPPLLPAFVAARRIADMAPAGLTQAAMAAFMTEGHFGAHLRRMRTLYGQRRRALLDAAPRILGPNLPVTAGEAGLH
AILWLPAGCDDFQAAEAARARGLAPSPLSFHRVTKGCPGLVLGYGNLAGSSLEEALQRLREAIITLI

Specific function: Could play a regulatory role in the transcription of the moc genes for rhizopine catabolism. Could also have an aminotransferase activity [H]

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=231, Percent_Identity=27.7056277056277, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI33469970, Length=231, Percent_Identity=27.7056277056277, Blast_Score=96, Evalue=8e-20,
Organism=Escherichia coli, GI1787710, Length=443, Percent_Identity=27.313769751693, Blast_Score=132, Evalue=8e-32,
Organism=Escherichia coli, GI1790797, Length=425, Percent_Identity=29.1764705882353, Blast_Score=124, Evalue=1e-29,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 58728; Mature: 58728

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHDRASSRMAAMASKSWLPRWGRWRKVVRSVLADMVALLSYSDWAESGSLKRSTSFIIME
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEC
PLPESAMPPPLPLALPDLDAPLHRRLYLALRDSILDGRLAEGAALPSSRGLAAQLGVARN
CCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCHHHHHHHHH
TVLAAYDLLAAEGFTEAHRGSATRVAARHPLVGAAPAGEEAPPSPLPPRTRAWGAAPPMI
HHHHHHHHHHHCCCCHHHCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEE
LVRDPFRPFAPGVPDLAAFPHAEWRRVLGRLWRRPPLELMGGIDPLGHAPLRHAIAEHLG
EEECCCCCCCCCCCCHHHCCCHHHHHHHHHHHCCCCHHHHCCCCCCCCHHHHHHHHHHHC
RSRAVRCDPAQVMIMGGSQQALDLVARVLLEPGEAVLVEDPCYGGLTGVLRAAGAQVQAV
CCCCEEECCCEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHCCCEEEEE
AVDGQGFDPELAERQCPSARLTFVTPSHQFPTGATMPLSRRLALIHWAERVGGWVIEDDY
EECCCCCCHHHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEECCC
DSDFHHAGSPTASLQGLDRGGRTLYLGTFSKSMFPGLRLGWLVVPPPLLPAFVAARRIAD
CCCCCCCCCCCHHHHCCCCCCCEEEEEECCHHHCCCCEECEEEECCHHHHHHHHHHHHHH
MAPAGLTQAAMAAFMTEGHFGAHLRRMRTLYGQRRRALLDAAPRILGPNLPVTAGEAGLH
HCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCE
AILWLPAGCDDFQAAEAARARGLAPSPLSFHRVTKGCPGLVLGYGNLAGSSLEEALQRLR
EEEEECCCCCHHHHHHHHHHCCCCCCCCHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHH
EAIITLI
HHHHHCC
>Mature Secondary Structure
MHDRASSRMAAMASKSWLPRWGRWRKVVRSVLADMVALLSYSDWAESGSLKRSTSFIIME
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEC
PLPESAMPPPLPLALPDLDAPLHRRLYLALRDSILDGRLAEGAALPSSRGLAAQLGVARN
CCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCHHHHHHHHH
TVLAAYDLLAAEGFTEAHRGSATRVAARHPLVGAAPAGEEAPPSPLPPRTRAWGAAPPMI
HHHHHHHHHHHCCCCHHHCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEE
LVRDPFRPFAPGVPDLAAFPHAEWRRVLGRLWRRPPLELMGGIDPLGHAPLRHAIAEHLG
EEECCCCCCCCCCCCHHHCCCHHHHHHHHHHHCCCCHHHHCCCCCCCCHHHHHHHHHHHC
RSRAVRCDPAQVMIMGGSQQALDLVARVLLEPGEAVLVEDPCYGGLTGVLRAAGAQVQAV
CCCCEEECCCEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHCCCEEEEE
AVDGQGFDPELAERQCPSARLTFVTPSHQFPTGATMPLSRRLALIHWAERVGGWVIEDDY
EECCCCCCHHHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEECCC
DSDFHHAGSPTASLQGLDRGGRTLYLGTFSKSMFPGLRLGWLVVPPPLLPAFVAARRIAD
CCCCCCCCCCCHHHHCCCCCCCEEEEEECCHHHCCCCEECEEEECCHHHHHHHHHHHHHH
MAPAGLTQAAMAAFMTEGHFGAHLRRMRTLYGQRRRALLDAAPRILGPNLPVTAGEAGLH
HCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCE
AILWLPAGCDDFQAAEAARARGLAPSPLSFHRVTKGCPGLVLGYGNLAGSSLEEALQRLR
EEEEECCCCCHHHHHHHHHHCCCCCCCCHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHH
EAIITLI
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7845353 [H]