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The map label for this gene is nrdR

Identifier: 83310018

GI number: 83310018

Start: 987311

End: 987772

Strand: Reverse

Name: nrdR

Synonym: amb0919

Alternate gene names: 83310018

Gene position: 987772-987311 (Counterclockwise)

Preceding gene: 83310019

Following gene: 83310014

Centisome position: 19.89

GC content: 57.58

Gene sequence:

>462_bases
ATGCGTTGTCCTTTTTGCGGACATGACGACACCCAGGTGAAAGATTCCCGCCCTACCGATGACAATGCCTCCATCCGCCG
CCGCCGGGCGTGTCCTGCCTGTGCCTCACGCTTCACCACTTCCGAGCGGGTGCAAATCCGCGATCTGGTGGTGATCAAGA
AGGACGGCAGCCGGTCCACCTTTGACCGCGACAAGGTGGTTAAATCGCTCCAGATCGCCTTGCGAAAACGTCCCGTGGAT
GAGGAGCAGATCGAACGCATCGTCAATGGCATCCATCGCCGCCTGGAGAGCTTGGGAGAGAACGAGGTTCCGTCCAAGCT
CATCGGCGAACTGGTCATGGATGTGCTGATAGGGATGGATCAGGTGGCCTATTTGCGATACGCCTCCGTCTATCGGAACT
TCCGCGAAGCCAAGGATTTTGGCGATTTTCTGGGGAAGATGGGACGGCAAGGCGATGACTAA

Upstream 100 bases:

>100_bases
ACGCTGCGGATTGAAATTCCTGTCTCGGTCATCCGCTGTTCTTGCTGGCGGCGACCATTTCCTGAATGATCAATCTGAAC
ATCGATGGGGGGGGGCGAGT

Downstream 100 bases:

>100_bases
AGCCGCATGACGATAAGCCTACAAGGTATTGGCCAATATCCCCGTTACTTTCCCCTGGAAGCCCCCCCCTTTACGGCAGA
AATAGCTATCCCAAAAATTC

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 153; Mature: 153

Protein sequence:

>153_residues
MRCPFCGHDDTQVKDSRPTDDNASIRRRRACPACASRFTTSERVQIRDLVVIKKDGSRSTFDRDKVVKSLQIALRKRPVD
EEQIERIVNGIHRRLESLGENEVPSKLIGELVMDVLIGMDQVAYLRYASVYRNFREAKDFGDFLGKMGRQGDD

Sequences:

>Translated_153_residues
MRCPFCGHDDTQVKDSRPTDDNASIRRRRACPACASRFTTSERVQIRDLVVIKKDGSRSTFDRDKVVKSLQIALRKRPVD
EEQIERIVNGIHRRLESLGENEVPSKLIGELVMDVLIGMDQVAYLRYASVYRNFREAKDFGDFLGKMGRQGDD
>Mature_153_residues
MRCPFCGHDDTQVKDSRPTDDNASIRRRRACPACASRFTTSERVQIRDLVVIKKDGSRSTFDRDKVVKSLQIALRKRPVD
EEQIERIVNGIHRRLESLGENEVPSKLIGELVMDVLIGMDQVAYLRYASVYRNFREAKDFGDFLGKMGRQGDD

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

Organism=Escherichia coli, GI1786615, Length=147, Percent_Identity=44.2176870748299, Blast_Score=131, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDR1_MAGSA (Q2W8V2)

Other databases:

- EMBL:   AP007255
- RefSeq:   YP_420282.1
- STRING:   Q2W8V2
- GeneID:   3802910
- GenomeReviews:   AP007255_GR
- KEGG:   mag:amb0919
- NMPDR:   fig|342108.5.peg.856
- eggNOG:   COG1327
- HOGENOM:   HBG351755
- OMA:   RRRRECK
- PhylomeDB:   Q2W8V2
- ProtClustDB:   PRK00464
- BioCyc:   MMAG342108:AMB0919-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00440
- InterPro:   IPR005144
- InterPro:   IPR003796
- TIGRFAMs:   TIGR00244

Pfam domain/function: PF03477 ATP-cone

EC number: NA

Molecular weight: Translated: 17548; Mature: 17548

Theoretical pI: Translated: 8.96; Mature: 8.96

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRCPFCGHDDTQVKDSRPTDDNASIRRRRACPACASRFTTSERVQIRDLVVIKKDGSRST
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHCCCCCCEEHHHEEEEECCCCCCH
FDRDKVVKSLQIALRKRPVDEEQIERIVNGIHRRLESLGENEVPSKLIGELVMDVLIGMD
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCHH
QVAYLRYASVYRNFREAKDFGDFLGKMGRQGDD
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MRCPFCGHDDTQVKDSRPTDDNASIRRRRACPACASRFTTSERVQIRDLVVIKKDGSRST
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHCCCCCCEEHHHEEEEECCCCCCH
FDRDKVVKSLQIALRKRPVDEEQIERIVNGIHRRLESLGENEVPSKLIGELVMDVLIGMD
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCHH
QVAYLRYASVYRNFREAKDFGDFLGKMGRQGDD
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA