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The map label for this gene is cph1 [H]

Identifier: 83310008

GI number: 83310008

Start: 977962

End: 978594

Strand: Reverse

Name: cph1 [H]

Synonym: amb0909

Alternate gene names: 83310008

Gene position: 978594-977962 (Counterclockwise)

Preceding gene: 83310009

Following gene: 83310004

Centisome position: 19.7

GC content: 54.98

Gene sequence:

>633_bases
ATGGTCAGCAGCTATCTCAGTCTGCTGGAGCGGCGCTATTCGGATCAGCTCGATGAGGCTGCGCGGGAATTTATTGGGTT
CGCTCGCGATGGGGCCAAGCGGTTAGACCGTCTGGTGCTTGATCTGCTGGAATTATCGCGTGTTAATAGATGTGGCGAAG
CTATTACCGCCATGCCAATCATGCCTGCGGTGCAATTGGCACTAACTAATCTGGGGATGGCGATCAAAGACAGCGGGGCG
ACGATCACTGTCGATGACGCGATCCGATCATCCTGGGTGATGGGAGATCCCACTCAGGTCATGAGGCTGTTCCAGAACCT
GATCGGCAACGCGCTCAAATACCGAAAGCCTGACGTAACACCGATTATCCGGATTGACGGTCGACACCTGGACCGTCATT
GGGAGTTCAGTGTGGGCGACAACGGCATTGGCATTGCGCCGGAGTATTTTGAGCGCATCTTTGGCATTTTCCAGCGTCTG
CACGCACGTGAAGAATACGACGGTACCGGGATCGGCCTTGCGATCAGCAAGAAGATCATTGAGCGACATTCCGGAAGCAT
TTGGCTGGCGTCGATGCCTGACGACGGAACGACCTTCTACTTTACGCTGCCGGAAGGTTCAGTCCCAACCTGA

Upstream 100 bases:

>100_bases
GCCATGCCCGCCGGAGATCATGACGGCCAAGGCGCTGTTACACCAACTCCTGGGACACGATCCTTATGTCGCCAGCCATG
ACCTCCGAGAACCGCTGCGG

Downstream 100 bases:

>100_bases
TCAACTGGTCCACAGACGAGAAATGGCACAACGGGGCCGGATCGGACCTTTGCCTTGAGCGGCGGCTATCGGAGGTGCAG
CAGTCATCCATCGCGCCGGG

Product: Signal transduction histidine kinase

Products: NA

Alternate protein names: Bacteriophytochrome cph1; Light-regulated histidine kinase 1 [H]

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MVSSYLSLLERRYSDQLDEAAREFIGFARDGAKRLDRLVLDLLELSRVNRCGEAITAMPIMPAVQLALTNLGMAIKDSGA
TITVDDAIRSSWVMGDPTQVMRLFQNLIGNALKYRKPDVTPIIRIDGRHLDRHWEFSVGDNGIGIAPEYFERIFGIFQRL
HAREEYDGTGIGLAISKKIIERHSGSIWLASMPDDGTTFYFTLPEGSVPT

Sequences:

>Translated_210_residues
MVSSYLSLLERRYSDQLDEAAREFIGFARDGAKRLDRLVLDLLELSRVNRCGEAITAMPIMPAVQLALTNLGMAIKDSGA
TITVDDAIRSSWVMGDPTQVMRLFQNLIGNALKYRKPDVTPIIRIDGRHLDRHWEFSVGDNGIGIAPEYFERIFGIFQRL
HAREEYDGTGIGLAISKKIIERHSGSIWLASMPDDGTTFYFTLPEGSVPT
>Mature_210_residues
MVSSYLSLLERRYSDQLDEAAREFIGFARDGAKRLDRLVLDLLELSRVNRCGEAITAMPIMPAVQLALTNLGMAIKDSGA
TITVDDAIRSSWVMGDPTQVMRLFQNLIGNALKYRKPDVTPIIRIDGRHLDRHWEFSVGDNGIGIAPEYFERIFGIFQRL
HAREEYDGTGIGLAISKKIIERHSGSIWLASMPDDGTTFYFTLPEGSVPT

Specific function: Regulatory photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region. Has also a slight blue shift

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=197, Percent_Identity=27.9187817258883, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1786600, Length=212, Percent_Identity=30.188679245283, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1786783, Length=114, Percent_Identity=36.8421052631579, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1790346, Length=178, Percent_Identity=31.4606741573034, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1786912, Length=108, Percent_Identity=34.2592592592593, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI87081816, Length=193, Percent_Identity=29.0155440414508, Blast_Score=64, Evalue=6e-12,
Organism=Escherichia coli, GI1788713, Length=209, Percent_Identity=24.4019138755981, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI48994928, Length=120, Percent_Identity=33.3333333333333, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1788393, Length=180, Percent_Identity=28.3333333333333, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1790436, Length=173, Percent_Identity=27.7456647398844, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR000014
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 23520; Mature: 23520

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSSYLSLLERRYSDQLDEAAREFIGFARDGAKRLDRLVLDLLELSRVNRCGEAITAMPI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MPAVQLALTNLGMAIKDSGATITVDDAIRSSWVMGDPTQVMRLFQNLIGNALKYRKPDVT
HHHHHHHHHHCCCEEECCCCEEEECHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
PIIRIDGRHLDRHWEFSVGDNGIGIAPEYFERIFGIFQRLHAREEYDGTGIGLAISKKII
EEEEECCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
ERHSGSIWLASMPDDGTTFYFTLPEGSVPT
HHCCCCEEEEECCCCCCEEEEECCCCCCCC
>Mature Secondary Structure
MVSSYLSLLERRYSDQLDEAAREFIGFARDGAKRLDRLVLDLLELSRVNRCGEAITAMPI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MPAVQLALTNLGMAIKDSGATITVDDAIRSSWVMGDPTQVMRLFQNLIGNALKYRKPDVT
HHHHHHHHHHCCCEEECCCCEEEECHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
PIIRIDGRHLDRHWEFSVGDNGIGIAPEYFERIFGIFQRLHAREEYDGTGIGLAISKKII
EEEEECCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
ERHSGSIWLASMPDDGTTFYFTLPEGSVPT
HHCCCCEEEEECCCCCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 9109482; 9278513; 10828948 [H]