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The map label for this gene is pdxH [H]

Identifier: 83309985

GI number: 83309985

Start: 945968

End: 946645

Strand: Reverse

Name: pdxH [H]

Synonym: amb0886

Alternate gene names: 83309985

Gene position: 946645-945968 (Counterclockwise)

Preceding gene: 83309988

Following gene: 83309984

Centisome position: 19.06

GC content: 66.81

Gene sequence:

>678_bases
ATGAAAAGGGGGTATGCGACGAAACGTCTACCATATGGCCTTGAATCTGGGCATTTTGAGGGCGTCGCGTCAACACCCGC
CGGTGAGAGAATGTCCGCACCCGAAGCCGACCCCCTGGTCCTGTTCCACAAGTGGATGGACGAGGCCGAAAAGGCCGAGC
CCAACGACCCCAACGCCATGGCCCTGGCCACCGCCGATGCGGAGGGACGGCCCAGCGTGCGCATGGTGCTGCTGAAGGGC
GCCGACCAGGACGGCTTCGTGTTCTTCACCAACCTGGAAAGCCGCAAGGGCCAGGAGCTGGCCGCCAATCCCCATGCCGC
CCTGTGCCTGCACTGGAAAAGCCTGCGGCGCCAGATCCGGGTCGAAGGGTCCATCACCCGGGTCTCGGACGAGGAAGCCG
ATGCCTATTTCGCCACCCGGGCGCGGGCCAGCCAGATCGGCGCCTGGGCTTCCATCCAGTCGCGGCCGCTCACCGGCCGG
TTCGAGCTGGAGAAGCGGGTGGGCGAATTCGCCGCCAAGTTCGGCCTGGGCAAGGTGCCGCGCCCGCCCCACTGGTCGGG
CTTCCGCCTGGCGCCCAGACGCATCGAATTCTGGCACGACCGGCCGTTCCGCCTGCACGACCGCTTCGACTATGTCCGCG
ACGGGGACGGCTGGCATCTGGAGCACCTCTACCCATGA

Upstream 100 bases:

>100_bases
CGCCGGTCTGCCCGAGCTTGGCATCGGCGCAGCCGCCCAGCAGCGACAGGGCGAGAAGGGCGGAAACGAACTTGGGGGCC
TGGGGGCGCATGGCGGTCTC

Downstream 100 bases:

>100_bases
GCCATCCAGCCGACCATGGCCGCCTGATGCGGCTGGCGACCTACGCCTCGACCGGCACCGCCGCCTTGCTGATCGCCGTC
AAGCTGGGCGCCTGGCTCGC

Product: pyridoxamine 5'-phosphate oxidase

Products: NA

Alternate protein names: PNP/PMP oxidase; PNPOx; Pyridoxal 5'-phosphate synthase [H]

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MKRGYATKRLPYGLESGHFEGVASTPAGERMSAPEADPLVLFHKWMDEAEKAEPNDPNAMALATADAEGRPSVRMVLLKG
ADQDGFVFFTNLESRKGQELAANPHAALCLHWKSLRRQIRVEGSITRVSDEEADAYFATRARASQIGAWASIQSRPLTGR
FELEKRVGEFAAKFGLGKVPRPPHWSGFRLAPRRIEFWHDRPFRLHDRFDYVRDGDGWHLEHLYP

Sequences:

>Translated_225_residues
MKRGYATKRLPYGLESGHFEGVASTPAGERMSAPEADPLVLFHKWMDEAEKAEPNDPNAMALATADAEGRPSVRMVLLKG
ADQDGFVFFTNLESRKGQELAANPHAALCLHWKSLRRQIRVEGSITRVSDEEADAYFATRARASQIGAWASIQSRPLTGR
FELEKRVGEFAAKFGLGKVPRPPHWSGFRLAPRRIEFWHDRPFRLHDRFDYVRDGDGWHLEHLYP
>Mature_225_residues
MKRGYATKRLPYGLESGHFEGVASTPAGERMSAPEADPLVLFHKWMDEAEKAEPNDPNAMALATADAEGRPSVRMVLLKG
ADQDGFVFFTNLESRKGQELAANPHAALCLHWKSLRRQIRVEGSITRVSDEEADAYFATRARASQIGAWASIQSRPLTGR
FELEKRVGEFAAKFGLGKVPRPPHWSGFRLAPRRIEFWHDRPFRLHDRFDYVRDGDGWHLEHLYP

Specific function: Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) [H]

COG id: COG0259

COG function: function code H; Pyridoxamine-phosphate oxidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxamine 5'-phosphate oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922498, Length=178, Percent_Identity=45.5056179775281, Blast_Score=160, Evalue=7e-40,
Organism=Escherichia coli, GI1787926, Length=201, Percent_Identity=45.273631840796, Blast_Score=179, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI17553712, Length=198, Percent_Identity=40.4040404040404, Blast_Score=145, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6319509, Length=196, Percent_Identity=42.8571428571429, Blast_Score=150, Evalue=2e-37,
Organism=Drosophila melanogaster, GI45551845, Length=206, Percent_Identity=41.747572815534, Blast_Score=147, Evalue=7e-36,
Organism=Drosophila melanogaster, GI24644901, Length=206, Percent_Identity=41.747572815534, Blast_Score=147, Evalue=7e-36,
Organism=Drosophila melanogaster, GI24644903, Length=172, Percent_Identity=33.1395348837209, Blast_Score=91, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000659
- InterPro:   IPR019740
- InterPro:   IPR019576
- InterPro:   IPR011576
- InterPro:   IPR012349
- InterPro:   IPR009002 [H]

Pfam domain/function: PF10590 PNPOx_C; PF01243 Pyridox_oxidase [H]

EC number: =1.4.3.5 [H]

Molecular weight: Translated: 25512; Mature: 25512

Theoretical pI: Translated: 9.01; Mature: 9.01

Prosite motif: PS01064 PYRIDOX_OXIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRGYATKRLPYGLESGHFEGVASTPAGERMSAPEADPLVLFHKWMDEAEKAEPNDPNAM
CCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCEEHHHHHHHHHHHCCCCCCCEE
ALATADAEGRPSVRMVLLKGADQDGFVFFTNLESRKGQELAANPHAALCLHWKSLRRQIR
EEEECCCCCCCCEEEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCEEEHHHHHHHHHEE
VEGSITRVSDEEADAYFATRARASQIGAWASIQSRPLTGRFELEKRVGEFAAKFGLGKVP
CCCCEEECCCCCCHHHHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCC
RPPHWSGFRLAPRRIEFWHDRPFRLHDRFDYVRDGDGWHLEHLYP
CCCCCCCEEECCCEEEEECCCCEEECCCCCEEECCCCEEECCCCC
>Mature Secondary Structure
MKRGYATKRLPYGLESGHFEGVASTPAGERMSAPEADPLVLFHKWMDEAEKAEPNDPNAM
CCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCEEHHHHHHHHHHHCCCCCCCEE
ALATADAEGRPSVRMVLLKGADQDGFVFFTNLESRKGQELAANPHAALCLHWKSLRRQIR
EEEECCCCCCCCEEEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCEEEHHHHHHHHHEE
VEGSITRVSDEEADAYFATRARASQIGAWASIQSRPLTGRFELEKRVGEFAAKFGLGKVP
CCCCEEECCCCCCHHHHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCC
RPPHWSGFRLAPRRIEFWHDRPFRLHDRFDYVRDGDGWHLEHLYP
CCCCCCCEEECCCEEEEECCCCEEECCCCCEEECCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA