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The map label for this gene is aspC [H]

Identifier: 83309893

GI number: 83309893

Start: 850574

End: 851740

Strand: Reverse

Name: aspC [H]

Synonym: amb0794

Alternate gene names: 83309893

Gene position: 851740-850574 (Counterclockwise)

Preceding gene: 83309894

Following gene: 83309885

Centisome position: 17.15

GC content: 64.78

Gene sequence:

>1167_bases
ATGACGGAAGACCTGAAATTCTCGGCGCGAGGCAGAGCGCTGGTCGGCCAAAAAATGTTCGCCGTCCTGGAACAAGCCCG
CCGGATCGAGACCGCCGGAGAGAAGGTCTACCATCTGGAACTGGGCAATCCCCGCCTTGCCCCCCATCCAGCCATGCTGT
CGCGCACCGTCCAGGCCCTGGTCGAGCGCGAGGTGGGCTATACCCAGTCCGCCGGGCACCCCTCTCTGCGCCAGGCCATC
GCCGACCTGCGCGCGCGCACCTGGGGCCATACCGTTACCGAAGCCAATGTGGTGATCAGCCCGGCCAACCTGATCATCAG
CCAGTTTCTTGATCTGGTCTGCGATCCAGGTGACCGGGTGGTATTCTTCACCCCCGCCTTCCCCAGCTATTGGGCGGCGG
CCATCCACATCGGCCTCAAGGTTGAGAGCGTGCCGCTGGACCTCGCCACCGGCTACGACCTCAGCGATGACGCCGTGGAC
CGCGCCCTGGCCCTGGCCCCCAAGGCGATCATTGTCAATTCCGCCAATAACCCCACGGGAGCCGTCTACGACCGCGCCCA
GTTGGAGCGCTTGGCGGTGGAGTGCGACCGGCGCGGTATCTGGCTGCTGTCAGATGAAACCTATGGCGAGATCAGCTTCG
GACGGCCGTTCCATACGCTGGGCGGGCTGGAACTGCCCCGGCTGGTGGTGATGTCGTCGTTCTCAAAGCTGTTCTCGGTA
CCGGGCTACCGCATCGGTTTTCTCATCGCCCACCCCAAGGTGGCCGAGAAATTCGCCCTGTCTGTGTCGACGCTGATTTC
CTGCCTGCCCATCTTCACCCAGTTGGGCTGCGTCGCGGCACTGGACCATCTGGACAAGTATACCGAGGAGGTGCGGCACC
ACTGCACCGTGATGACCGACTGGTGCTCTGAGGCCTTGCGAAAGAGCCAGCGCCTGGCCTTCGTGCCGCCCAAGGCGGGG
TTCTACTTCTTCCTCGACATTTCGGCCTGCGGCCTGGACGACCTCAGCTTCTCCAGCATGCTGCTGGAACGCCACCAGAC
CGCCGTGACGCCGGGCAGCAGCTTCTCGCCCGACATGACCGGCCACATCCGCATCGCCACCTGCGGCGCGGCCCTCGACG
TCCACGAGGGCGTCCGCCGAGTGGTGGCCCTGGCGGAATCCCTTTGA

Upstream 100 bases:

>100_bases
GGAAGTGACGGGGGCCTCTGGTTCTGGAAATAGTATCTTAAGCTTTCAACGGCAGATTCGGGGGCAGTGATCGAGCCGCC
GAGACAAGGGCAGAATACCC

Downstream 100 bases:

>100_bases
GGGCGGCGGCGTAGCATCGGGCTATCGCCCGCACCCATTTGGGGCGATGCCCCAAACCCCCTTTTGATTCATAAATAGAA
GGGAGGTTTGGAGGCTTGCC

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 388; Mature: 387

Protein sequence:

>388_residues
MTEDLKFSARGRALVGQKMFAVLEQARRIETAGEKVYHLELGNPRLAPHPAMLSRTVQALVEREVGYTQSAGHPSLRQAI
ADLRARTWGHTVTEANVVISPANLIISQFLDLVCDPGDRVVFFTPAFPSYWAAAIHIGLKVESVPLDLATGYDLSDDAVD
RALALAPKAIIVNSANNPTGAVYDRAQLERLAVECDRRGIWLLSDETYGEISFGRPFHTLGGLELPRLVVMSSFSKLFSV
PGYRIGFLIAHPKVAEKFALSVSTLISCLPIFTQLGCVAALDHLDKYTEEVRHHCTVMTDWCSEALRKSQRLAFVPPKAG
FYFFLDISACGLDDLSFSSMLLERHQTAVTPGSSFSPDMTGHIRIATCGAALDVHEGVRRVVALAESL

Sequences:

>Translated_388_residues
MTEDLKFSARGRALVGQKMFAVLEQARRIETAGEKVYHLELGNPRLAPHPAMLSRTVQALVEREVGYTQSAGHPSLRQAI
ADLRARTWGHTVTEANVVISPANLIISQFLDLVCDPGDRVVFFTPAFPSYWAAAIHIGLKVESVPLDLATGYDLSDDAVD
RALALAPKAIIVNSANNPTGAVYDRAQLERLAVECDRRGIWLLSDETYGEISFGRPFHTLGGLELPRLVVMSSFSKLFSV
PGYRIGFLIAHPKVAEKFALSVSTLISCLPIFTQLGCVAALDHLDKYTEEVRHHCTVMTDWCSEALRKSQRLAFVPPKAG
FYFFLDISACGLDDLSFSSMLLERHQTAVTPGSSFSPDMTGHIRIATCGAALDVHEGVRRVVALAESL
>Mature_387_residues
TEDLKFSARGRALVGQKMFAVLEQARRIETAGEKVYHLELGNPRLAPHPAMLSRTVQALVEREVGYTQSAGHPSLRQAIA
DLRARTWGHTVTEANVVISPANLIISQFLDLVCDPGDRVVFFTPAFPSYWAAAIHIGLKVESVPLDLATGYDLSDDAVDR
ALALAPKAIIVNSANNPTGAVYDRAQLERLAVECDRRGIWLLSDETYGEISFGRPFHTLGGLELPRLVVMSSFSKLFSVP
GYRIGFLIAHPKVAEKFALSVSTLISCLPIFTQLGCVAALDHLDKYTEEVRHHCTVMTDWCSEALRKSQRLAFVPPKAGF
YFFLDISACGLDDLSFSSMLLERHQTAVTPGSSFSPDMTGHIRIATCGAALDVHEGVRRVVALAESL

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=390, Percent_Identity=22.8205128205128, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI56713256, Length=363, Percent_Identity=22.8650137741047, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI4507369, Length=240, Percent_Identity=21.6666666666667, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1788722, Length=366, Percent_Identity=23.4972677595628, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1790797, Length=329, Percent_Identity=28.8753799392097, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1788627, Length=374, Percent_Identity=23.7967914438503, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1786816, Length=315, Percent_Identity=24.7619047619048, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1787710, Length=335, Percent_Identity=27.1641791044776, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787909, Length=331, Percent_Identity=22.6586102719033, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17567663, Length=381, Percent_Identity=24.6719160104987, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17567369, Length=324, Percent_Identity=22.5308641975309, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71994476, Length=325, Percent_Identity=24.3076923076923, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71994472, Length=325, Percent_Identity=24.3076923076923, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322401, Length=301, Percent_Identity=23.5880398671096, Blast_Score=78, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6320317, Length=164, Percent_Identity=28.0487804878049, Blast_Score=64, Evalue=6e-11,
Organism=Drosophila melanogaster, GI28573069, Length=329, Percent_Identity=22.7963525835866, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24646114, Length=329, Percent_Identity=22.7963525835866, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI28573067, Length=329, Percent_Identity=22.7963525835866, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI28573065, Length=329, Percent_Identity=22.7963525835866, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI18859735, Length=371, Percent_Identity=22.911051212938, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 42494; Mature: 42363

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEDLKFSARGRALVGQKMFAVLEQARRIETAGEKVYHLELGNPRLAPHPAMLSRTVQAL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHH
VEREVGYTQSAGHPSLRQAIADLRARTWGHTVTEANVVISPANLIISQFLDLVCDPGDRV
HHHHCCCCCCCCCHHHHHHHHHHHHHHCCCEEEECEEEECHHHHHHHHHHHHHCCCCCEE
VFFTPAFPSYWAAAIHIGLKVESVPLDLATGYDLSDDAVDRALALAPKAIIVNSANNPTG
EEECCCCHHHHHHHHEECEEEEECCEEEECCCCCCHHHHHHHHHHCCCEEEEECCCCCCC
AVYDRAQLERLAVECDRRGIWLLSDETYGEISFGRPFHTLGGLELPRLVVMSSFSKLFSV
CHHHHHHHHHHHHHHCCCCEEEECCCCCCCEECCCCHHHCCCCCHHHHHHHHHHHHHHCC
PGYRIGFLIAHPKVAEKFALSVSTLISCLPIFTQLGCVAALDHLDKYTEEVRHHCTVMTD
CCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WCSEALRKSQRLAFVPPKAGFYFFLDISACGLDDLSFSSMLLERHQTAVTPGSSFSPDMT
HHHHHHHHCCCEEEECCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
GHIRIATCGAALDVHEGVRRVVALAESL
CCEEEEEECCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TEDLKFSARGRALVGQKMFAVLEQARRIETAGEKVYHLELGNPRLAPHPAMLSRTVQAL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHH
VEREVGYTQSAGHPSLRQAIADLRARTWGHTVTEANVVISPANLIISQFLDLVCDPGDRV
HHHHCCCCCCCCCHHHHHHHHHHHHHHCCCEEEECEEEECHHHHHHHHHHHHHCCCCCEE
VFFTPAFPSYWAAAIHIGLKVESVPLDLATGYDLSDDAVDRALALAPKAIIVNSANNPTG
EEECCCCHHHHHHHHEECEEEEECCEEEECCCCCCHHHHHHHHHHCCCEEEEECCCCCCC
AVYDRAQLERLAVECDRRGIWLLSDETYGEISFGRPFHTLGGLELPRLVVMSSFSKLFSV
CHHHHHHHHHHHHHHCCCCEEEECCCCCCCEECCCCHHHCCCCCHHHHHHHHHHHHHHCC
PGYRIGFLIAHPKVAEKFALSVSTLISCLPIFTQLGCVAALDHLDKYTEEVRHHCTVMTD
CCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WCSEALRKSQRLAFVPPKAGFYFFLDISACGLDDLSFSSMLLERHQTAVTPGSSFSPDMT
HHHHHHHHCCCEEEECCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
GHIRIATCGAALDVHEGVRRVVALAESL
CCEEEEEECCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]