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The map label for this gene is ctaB1 [H]

Identifier: 83309839

GI number: 83309839

Start: 802826

End: 803773

Strand: Reverse

Name: ctaB1 [H]

Synonym: amb0740

Alternate gene names: 83309839

Gene position: 803773-802826 (Counterclockwise)

Preceding gene: 83309840

Following gene: 83309837

Centisome position: 16.18

GC content: 66.35

Gene sequence:

>948_bases
GTGGCTTTACGTATCCATTACCGGCATCGTCGTGTATCTTATGCTGTATCACATATACATTTGACCTGCGGAGCAACCGC
GGGCGCGGAGGCGGGTTTGACGTTCAGGCAATACATCGAGCTCTTGAAGCCGCGCATCGCCCTGATGATCGCGCTGACGG
CCATCACCGGCTATGGCGCGGTGGCGACCAAGGTCGACCCGGTGGCCCTGCTGCTGCTGACCCTGGCCATGATACTCGGC
TCGGCCGCCTCGGCGGTGTTCAACCATGTCTGGGACCGCGACATCGACCGGCTGATGCGCCGCACCTCGCGCCGGCCCAT
GGCCACCGGCGCCGGCACCCCGGCCCTGGGCTTCGCCCTGGCGGTGGTGCTGATGGTGGCCGGCATGGCCCTGGCCAACG
CCGCCTTCAATTGGGTGGTGGCGCTGCATCTGTTCCTGGGCGGCTTCGTCTATGTGGCCATCTACACCGTCTGGCTGAAG
CGCCGCCATTGGACAAATATCATCATCGGCGGCGCGGCCGGCAGTTTCGCCGTCCTGGCCGGAGCGGCGGCGGTGGATCA
GACCCAATGGCTGCTGCCCATGGTCCTGGCCCTGGTGCTGTTCCTGTGGACGCCCAGCCATTTCTGGTCGCTGGCCATCC
TGCTTGCCGACGACTACCGCCAGGCGGGCGTGCCCATGCTGCCGGTGGTGGTGGGCGCCAAGCGTACCGCCTGGTGCATC
CTGGCCAACACCGTGATCCTGGTGGGGGCCTCGCTGCTGCCCTGGGGGCTGGGCCTGCTGGGCAATGTCTACGGTTTCGT
GGCCGCGGTTTCGGGCGCCGTGCTGCTGGGCTTCAACGTGGTACTGGTCAGGGACACCAGCCGCCGCTGGGCCGGGTGGA
ACTTCGCCGCCTCCATGCCCTATCTGCTGCTGCTGTTCATCGCCGTCTTCGCCGACAAGCACTGGTAG

Upstream 100 bases:

>100_bases
TGGCGGCGGTGGTGGCGCCCATGGTCGCCCTGACCCTGGTCCGCGCCCTCAAGGGGCAGTTCGACCTGCACCCGAAAATC
GCCCGCTGGACCTTGCCGCT

Downstream 100 bases:

>100_bases
GGGGAGTCTTTCCGCCCCTCAGGCGCCGGGTGGGTTTCTTCGAAACCCTTGGGCCTGGCGGCATCGCCGATTACTGCGCC
ATTTCGGCCAGATTGACGAA

Product: Protoheme IX farnesyltransferase

Products: NA

Alternate protein names: Heme B farnesyltransferase 1; Heme O synthase 1 [H]

Number of amino acids: Translated: 315; Mature: 314

Protein sequence:

>315_residues
MALRIHYRHRRVSYAVSHIHLTCGATAGAEAGLTFRQYIELLKPRIALMIALTAITGYGAVATKVDPVALLLLTLAMILG
SAASAVFNHVWDRDIDRLMRRTSRRPMATGAGTPALGFALAVVLMVAGMALANAAFNWVVALHLFLGGFVYVAIYTVWLK
RRHWTNIIIGGAAGSFAVLAGAAAVDQTQWLLPMVLALVLFLWTPSHFWSLAILLADDYRQAGVPMLPVVVGAKRTAWCI
LANTVILVGASLLPWGLGLLGNVYGFVAAVSGAVLLGFNVVLVRDTSRRWAGWNFAASMPYLLLLFIAVFADKHW

Sequences:

>Translated_315_residues
MALRIHYRHRRVSYAVSHIHLTCGATAGAEAGLTFRQYIELLKPRIALMIALTAITGYGAVATKVDPVALLLLTLAMILG
SAASAVFNHVWDRDIDRLMRRTSRRPMATGAGTPALGFALAVVLMVAGMALANAAFNWVVALHLFLGGFVYVAIYTVWLK
RRHWTNIIIGGAAGSFAVLAGAAAVDQTQWLLPMVLALVLFLWTPSHFWSLAILLADDYRQAGVPMLPVVVGAKRTAWCI
LANTVILVGASLLPWGLGLLGNVYGFVAAVSGAVLLGFNVVLVRDTSRRWAGWNFAASMPYLLLLFIAVFADKHW
>Mature_314_residues
ALRIHYRHRRVSYAVSHIHLTCGATAGAEAGLTFRQYIELLKPRIALMIALTAITGYGAVATKVDPVALLLLTLAMILGS
AASAVFNHVWDRDIDRLMRRTSRRPMATGAGTPALGFALAVVLMVAGMALANAAFNWVVALHLFLGGFVYVAIYTVWLKR
RHWTNIIIGGAAGSFAVLAGAAAVDQTQWLLPMVLALVLFLWTPSHFWSLAILLADDYRQAGVPMLPVVVGAKRTAWCIL
ANTVILVGASLLPWGLGLLGNVYGFVAAVSGAVLLGFNVVLVRDTSRRWAGWNFAASMPYLLLLFIAVFADKHW

Specific function: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group [H]

COG id: COG0109

COG function: function code O; Polyprenyltransferase (cytochrome oxidase assembly factor)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786631, Length=205, Percent_Identity=31.7073170731707, Blast_Score=93, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6325085, Length=223, Percent_Identity=27.8026905829596, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI19921064, Length=224, Percent_Identity=32.1428571428571, Blast_Score=81, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006369
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 34106; Mature: 33975

Theoretical pI: Translated: 10.75; Mature: 10.75

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALRIHYRHRRVSYAVSHIHLTCGATAGAEAGLTFRQYIELLKPRIALMIALTAITGYGA
CEEEEEHHHHHHHHHHHHEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
VATKVDPVALLLLTLAMILGSAASAVFNHVWDRDIDRLMRRTSRRPMATGAGTPALGFAL
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
AVVLMVAGMALANAAFNWVVALHLFLGGFVYVAIYTVWLKRRHWTNIIIGGAAGSFAVLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHH
GAAAVDQTQWLLPMVLALVLFLWTPSHFWSLAILLADDYRQAGVPMLPVVVGAKRTAWCI
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHH
LANTVILVGASLLPWGLGLLGNVYGFVAAVSGAVLLGFNVVLVRDTSRRWAGWNFAASMP
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHH
YLLLLFIAVFADKHW
HHHHHHHHHHHCCCC
>Mature Secondary Structure 
ALRIHYRHRRVSYAVSHIHLTCGATAGAEAGLTFRQYIELLKPRIALMIALTAITGYGA
EEEEEHHHHHHHHHHHHEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
VATKVDPVALLLLTLAMILGSAASAVFNHVWDRDIDRLMRRTSRRPMATGAGTPALGFAL
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
AVVLMVAGMALANAAFNWVVALHLFLGGFVYVAIYTVWLKRRHWTNIIIGGAAGSFAVLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHH
GAAAVDQTQWLLPMVLALVLFLWTPSHFWSLAILLADDYRQAGVPMLPVVVGAKRTAWCI
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHH
LANTVILVGASLLPWGLGLLGNVYGFVAAVSGAVLLGFNVVLVRDTSRRWAGWNFAASMP
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHH
YLLLLFIAVFADKHW
HHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA