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The map label for this gene is 83309812

Identifier: 83309812

GI number: 83309812

Start: 772835

End: 773881

Strand: Reverse

Name: 83309812

Synonym: amb0713

Alternate gene names: NA

Gene position: 773881-772835 (Counterclockwise)

Preceding gene: 83309813

Following gene: 83309809

Centisome position: 15.58

GC content: 69.15

Gene sequence:

>1047_bases
ATGACCGAGATTTCCATCGCCGGACGCCCCATCGGGCCGGATCATCCGCCCTTCATCATCGCCGAGATGTCGGCCAACCA
TAACGGCGACCTGGGCCGCGCCCTGGCCCTGCTGGAGGCGGCGGCGGCGGCGGGCGCCGACGCGGTCAAGCTGCAGACGC
TGAAGCCCGACGCCATTACCATCGATTGCGACCGGCCCGACTTCGTCATCGAGGGCGGCCCCTGGGGCGGGCGCAAGCTC
TATGACCTCTACGCCGAGGCCCAGACCCCGTGGGACTGGCACGCCAAGCTGTTCGAGCGGGGCAGGGAACTGGGACTGAT
CGTCTTTTCCTCGCCCTTCGACAAGGCGGCGGTGGACTTCCTGGCGGGTCTCGACGCCCCGGCCTTCAAGATCGCCAGCT
TCGAGATGGCCGATCCCGGGCTGGTGGCCCATGCGGCGGCCAAGGGCAAGCCGATCATCGTGTCGACCGGCATGGCCGGG
CTGGGCGACATCGCCGCCACGGTGGAGACGGTGCGCCGGGCCGGCAACGACCAACTGGTGCTGCTCCACTGCATCAGCTC
GTACCCGGCCCCCACCGAGGAGGCCAATCTGGCCACCATTCCCCACATGGCCCAGGCCTTCGGCGTGCCGGTCGGCCTGT
CCGACCACACCCAGGGCACGGCGGTGGCGGTGACGGCGGTGGCGCTGGGCGCCTGCGTCGTCGAGAAGCACTTCACCCTG
CGCCGCGCCGATGGCGGGCTCGATTCCCATTTCTCGCTGGAACCCGAGGAACTGGCCCAACTGGTCAAGGATTGCCGCAC
CGCCTGGGTGGCGCGCGGACGCATCTCCTATGCCCTGGCCGAGTGCGAGCAGGGCTCCAAGGCCTTCCGCCGCTCGCTCT
ATGTGGTCGAGGACCTGCACCCCGGCGAAATCATCACCGAGGACAAGGTGCGCTCCATCCGCCCCGGCTATGGGCTGGAG
CCCAAGTTCCTGCCCGAGATCCTGGGGCGCAAGGCACGCAAGGCGGTGCCGCGCGGCACCGCCTTCGACTGGTCGATGAT
CGAGTAG

Upstream 100 bases:

>100_bases
GCGCCATGTCGGCCGCCGCCGCCAAACTGTGCGACGGACGGGGCGCCGCCCGCACCGTCGACGCAATCCGACGCCTGCCG
TCCCTGAAAGGCCTTGCCCC

Downstream 100 bases:

>100_bases
GATGGAACCGATCCGTCATCCCGACGCCCTCGGGCGGAGGGATCTCGTCCTGGCACGGCCGTTCAGAACCGGCACCGCCG
CTCCAGGCGGAGATCCTTCG

Product: sialic acid synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 348; Mature: 347

Protein sequence:

>348_residues
MTEISIAGRPIGPDHPPFIIAEMSANHNGDLGRALALLEAAAAAGADAVKLQTLKPDAITIDCDRPDFVIEGGPWGGRKL
YDLYAEAQTPWDWHAKLFERGRELGLIVFSSPFDKAAVDFLAGLDAPAFKIASFEMADPGLVAHAAAKGKPIIVSTGMAG
LGDIAATVETVRRAGNDQLVLLHCISSYPAPTEEANLATIPHMAQAFGVPVGLSDHTQGTAVAVTAVALGACVVEKHFTL
RRADGGLDSHFSLEPEELAQLVKDCRTAWVARGRISYALAECEQGSKAFRRSLYVVEDLHPGEIITEDKVRSIRPGYGLE
PKFLPEILGRKARKAVPRGTAFDWSMIE

Sequences:

>Translated_348_residues
MTEISIAGRPIGPDHPPFIIAEMSANHNGDLGRALALLEAAAAAGADAVKLQTLKPDAITIDCDRPDFVIEGGPWGGRKL
YDLYAEAQTPWDWHAKLFERGRELGLIVFSSPFDKAAVDFLAGLDAPAFKIASFEMADPGLVAHAAAKGKPIIVSTGMAG
LGDIAATVETVRRAGNDQLVLLHCISSYPAPTEEANLATIPHMAQAFGVPVGLSDHTQGTAVAVTAVALGACVVEKHFTL
RRADGGLDSHFSLEPEELAQLVKDCRTAWVARGRISYALAECEQGSKAFRRSLYVVEDLHPGEIITEDKVRSIRPGYGLE
PKFLPEILGRKARKAVPRGTAFDWSMIE
>Mature_347_residues
TEISIAGRPIGPDHPPFIIAEMSANHNGDLGRALALLEAAAAAGADAVKLQTLKPDAITIDCDRPDFVIEGGPWGGRKLY
DLYAEAQTPWDWHAKLFERGRELGLIVFSSPFDKAAVDFLAGLDAPAFKIASFEMADPGLVAHAAAKGKPIIVSTGMAGL
GDIAATVETVRRAGNDQLVLLHCISSYPAPTEEANLATIPHMAQAFGVPVGLSDHTQGTAVAVTAVALGACVVEKHFTLR
RADGGLDSHFSLEPEELAQLVKDCRTAWVARGRISYALAECEQGSKAFRRSLYVVEDLHPGEIITEDKVRSIRPGYGLEP
KFLPEILGRKARKAVPRGTAFDWSMIE

Specific function: Unknown

COG id: COG2089

COG function: function code M; Sialic acid synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis spsE [H]

Homologues:

Organism=Homo sapiens, GI12056473, Length=332, Percent_Identity=32.8313253012048, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI21357081, Length=250, Percent_Identity=32, Blast_Score=129, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006190
- InterPro:   IPR013785
- InterPro:   IPR013132
- InterPro:   IPR013974 [H]

Pfam domain/function: PF03102 NeuB; PF08666 SAF [H]

EC number: NA

Molecular weight: Translated: 37284; Mature: 37153

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: PS50844 AFP_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEISIAGRPIGPDHPPFIIAEMSANHNGDLGRALALLEAAAAAGADAVKLQTLKPDAIT
CCCEEECCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCEEE
IDCDRPDFVIEGGPWGGRKLYDLYAEAQTPWDWHAKLFERGRELGLIVFSSPFDKAAVDF
EECCCCCEEEECCCCCCCHHHHHHHCCCCCHHHHHHHHHCCCEEEEEEEECCCCHHHHHH
LAGLDAPAFKIASFEMADPGLVAHAAAKGKPIIVSTGMAGLGDIAATVETVRRAGNDQLV
HHCCCCCCEEEEEECCCCCCCEEEHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCEE
LLHCISSYPAPTEEANLATIPHMAQAFGVPVGLSDHTQGTAVAVTAVALGACVVEKHFTL
EEEEHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEE
RRADGGLDSHFSLEPEELAQLVKDCRTAWVARGRISYALAECEQGSKAFRRSLYVVEDLH
EECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCHHHHHHHHEEEEECCC
PGEIITEDKVRSIRPGYGLEPKFLPEILGRKARKAVPRGTAFDWSMIE
CCCEECCCHHHHCCCCCCCCHHHHHHHHCHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
TEISIAGRPIGPDHPPFIIAEMSANHNGDLGRALALLEAAAAAGADAVKLQTLKPDAIT
CCEEECCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCEEE
IDCDRPDFVIEGGPWGGRKLYDLYAEAQTPWDWHAKLFERGRELGLIVFSSPFDKAAVDF
EECCCCCEEEECCCCCCCHHHHHHHCCCCCHHHHHHHHHCCCEEEEEEEECCCCHHHHHH
LAGLDAPAFKIASFEMADPGLVAHAAAKGKPIIVSTGMAGLGDIAATVETVRRAGNDQLV
HHCCCCCCEEEEEECCCCCCCEEEHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCEE
LLHCISSYPAPTEEANLATIPHMAQAFGVPVGLSDHTQGTAVAVTAVALGACVVEKHFTL
EEEEHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEE
RRADGGLDSHFSLEPEELAQLVKDCRTAWVARGRISYALAECEQGSKAFRRSLYVVEDLH
EECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCHHHHHHHHEEEEECCC
PGEIITEDKVRSIRPGYGLEPKFLPEILGRKARKAVPRGTAFDWSMIE
CCCEECCCHHHHCCCCCCCCHHHHHHHHCHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]