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The map label for this gene is divL [H]

Identifier: 83309724

GI number: 83309724

Start: 672161

End: 674695

Strand: Reverse

Name: divL [H]

Synonym: amb0625

Alternate gene names: 83309724

Gene position: 674695-672161 (Counterclockwise)

Preceding gene: 83309726

Following gene: 83309723

Centisome position: 13.58

GC content: 70.14

Gene sequence:

>2535_bases
TTGTCTTTTGCGCCGCGCATCGGCACTTTGGGACCCCTATGGGGAGATGATGGAATGCGCGCGGCTTTCGCGGCGGGATT
GGCGTTGATGCTGGCGGCGGGCGGAGCGGCGGCCGAAGAGGCGCCGGCCCTGGCGTCGCTGCGCTTCGACCCCCTGTCCC
TGGGCATCGGTGCCCTGCTGGTCCTGGTCCCGGCCCTGGCCGTGCTGGCGCTGCTGCGCTGGCGCATGGTGAGTCTGGCC
GCCGATGCCGGTCGCGCCGTCATCCTGGCCGATCGCCTGACCGAGAGCCTGCTGGCCGCGCCCGACGGCTTTTACGCCTG
GCTGGGCGAGCGCGAGATCTGCTCGCGGCGTCTGGCCGTGCTGCTGGGTCTGTTCGGCGGCACGGAATCCGCCTTCATGG
ATGTGCTGGAATCCTTCGCCGCCGCCGATGCCGCCCAGTTGGACAGCGCGGCGCGGCGCCTGCGCGAGGAGGGCCAGGGA
TTCGAGCTGGAATTGCGCCTGCGGGACGGCGGGCGCCGCGTCCGGGCGGTGGGGGTTCGCGCCTGCGGCCCCGAGGGCGC
AGCCCTGGCCGATCTGGTGTGGATGCACGACGTCACGGAAGGGGCAGCCTTCGAGGCGGAGCTGGCCTCGCGCCTGGCCG
GGCTGGTGGTCGAGCGCGAACGGATCGAGGGATTGCTGGGCGTATTGCCCATTCCCGCCTGGGTCCGCGACGACGACCTG
TCCCTGCTGCATGTCAACCGGGCCTATGCCCGGGCGGTGGACGTGGCCTCGCCCCTGGCGGCGGTGGCGGGACAGATCGA
GCTGGCCTCGGACGGCTCGGTGCGCGAAGCCCGCGCCCTGGCGGCCCGCGCCCGGGCGGCCGGCGAGCCCCGGTCAGAAT
CCTTCCATCTGGTGCTGGGCGGCCAACGCCGCTTCACCGAGATCACCGAGGCCCCCTTCGAGGCCGAGGATGGCGGCCTG
CTGACCGCCGGCTATGCCCTCGACCTCACCCGCGTCGAGGAGCTGCAGCAGGAGCTGGCCCGTCATGCCAGCGCCCACGC
CCAGGTGCTGGAGCATCTGGCTACCGCCATCGCCATCTTTTCCACCGACACCCGCCTCACCTTCTTCAACACCGCCTTCA
CCCGGCTGTGGCGCCTGGAGGCCGAGTGGCTGGCGGCCCAGCCCACCTACGGCGCCGTGCTGGATTCCCTGCGCGAGCGG
CGGCTGCTGCCCGAGGTCGCCGATTACCGCGCCTACAAGGAAGACGAGCTGAAGCGCTTCATCTCGCTGATCGACGCCGC
CGAGACCCTGCTCCACCTGCCCGACGGCCGCACGCTCCGGCGCATGATCGCCGCCCATCCCTATGGCGGCCTGATCTTCA
CCTACGAGGACGTCACCGACACCCTGGCTCTGGAGCGTTCGTTCAATACCGCCCTGGCGGTCCAGCGCGAGACCCTGGAC
CATCTGCACGAGGGCGTGGCGGTGTTCAAGGGTGACGGCCGGCTGCGCCTGTTCAATCCGGCCTATGCCCGGATCTGGAA
TCTGGCCCCGTCCATGCTGGAGTCCGAGCCGCATCTCAACGAACTGGTCGAGGCCCACCGGCCCTATTTCGAAGGCGGCG
CCGAACGCGCCTCGGTGTGGCCCGAAATGCGCGAGCGCCTGATGGCCCTGTTCAACACCCGCGCCCCCCAAAGCGGCCGG
GTCGAGCGCCTGGACGATTCCATCGTCGACTTCGCCTCGGTGCCGCTGCCCGACGGCGCCATGCTGCTGACCTGGCTGGA
CGTCACCGATTCCGCCCGGGTGGAGCGCGCCCTGCGCGAGCGCAACGAGGCCCTGGCCGCCGCCGACCTGCTGAAGAGCG
AATTCATCGCCAATGTCTCGGCCGAGGTCAGAAAGCCGCTAACCACGGTGATCGGCTTTTCCGAAATGCTGGCCGCCGAG
TATTTTGGCAAGCTCAACAAGCGCCAGCACGAATACGCCCGCGGCATCACCGAGGCGGGGCAGGGGCTGCAGGCGCTGAT
TTCCGACATCCTCGATCTCGCCGCCATCGAGGCTGGGCAGATGGCCCTGGAACTGGACACCGTCGACGTCCACCCCATGC
TGTCCGGCGTGCTGGGGCTGGTGCGCGAGAGGGTGCGGGAAAAGAAGGTCACCCTTGACTTCGACTGTCCCCTGGACATC
GGCTGGATCGTCGCCGACGAGCGCCGGCTGCGCCAGGTGCTGTTCAACCTGCTGGGCAACGCCTTGAAGCGCACCCCGTC
GGGGGGAAAGGTCAGCGTGCGGGCCGAGCGGCGGCCGTCGGAACTGGCGCTGACCATCAGCGACACCGGCACCGGCCTTT
CGGATGAGCAGCGCGAGCGGCTGTTCGGCGGCTTTGCCACCGGCGGGCGGCGCGAAGCCTTGCCCGCCGGCCGGGCCGAC
GACGATTCCGGCATCGGCCTGGCCCTGGTGCAGCGCTTCGTCGACCTCCATGGCGGAAGGGTGGAATTGGCATCGGCGCC
CGGCGAGGGTACGGTGGTGACGGTACGCCTGCCGGTGGGGTCGGGGGCGACATGA

Upstream 100 bases:

>100_bases
GCCTTGGCCATCATCCAGTCGTAAAGGCCCTTCAGCATCATTCTCACTCCCCAGGAACGGGCGAGGTGTAGCAGCAGCGG
GGCAAAGGGGCAACCACCCC

Downstream 100 bases:

>100_bases
ACTTGAGCGGAGTGGATGGGTGATGATGGCGATTCTGGGACGGGGATGGGGGGTGGCCATTGCGGCCTTGGTGTTGATGG
CCGCCGCGCTGCCCGCCGGG

Product: PAS/PAC domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 844; Mature: 843

Protein sequence:

>844_residues
MSFAPRIGTLGPLWGDDGMRAAFAAGLALMLAAGGAAAEEAPALASLRFDPLSLGIGALLVLVPALAVLALLRWRMVSLA
ADAGRAVILADRLTESLLAAPDGFYAWLGEREICSRRLAVLLGLFGGTESAFMDVLESFAAADAAQLDSAARRLREEGQG
FELELRLRDGGRRVRAVGVRACGPEGAALADLVWMHDVTEGAAFEAELASRLAGLVVERERIEGLLGVLPIPAWVRDDDL
SLLHVNRAYARAVDVASPLAAVAGQIELASDGSVREARALAARARAAGEPRSESFHLVLGGQRRFTEITEAPFEAEDGGL
LTAGYALDLTRVEELQQELARHASAHAQVLEHLATAIAIFSTDTRLTFFNTAFTRLWRLEAEWLAAQPTYGAVLDSLRER
RLLPEVADYRAYKEDELKRFISLIDAAETLLHLPDGRTLRRMIAAHPYGGLIFTYEDVTDTLALERSFNTALAVQRETLD
HLHEGVAVFKGDGRLRLFNPAYARIWNLAPSMLESEPHLNELVEAHRPYFEGGAERASVWPEMRERLMALFNTRAPQSGR
VERLDDSIVDFASVPLPDGAMLLTWLDVTDSARVERALRERNEALAAADLLKSEFIANVSAEVRKPLTTVIGFSEMLAAE
YFGKLNKRQHEYARGITEAGQGLQALISDILDLAAIEAGQMALELDTVDVHPMLSGVLGLVRERVREKKVTLDFDCPLDI
GWIVADERRLRQVLFNLLGNALKRTPSGGKVSVRAERRPSELALTISDTGTGLSDEQRERLFGGFATGGRREALPAGRAD
DDSGIGLALVQRFVDLHGGRVELASAPGEGTVVTVRLPVGSGAT

Sequences:

>Translated_844_residues
MSFAPRIGTLGPLWGDDGMRAAFAAGLALMLAAGGAAAEEAPALASLRFDPLSLGIGALLVLVPALAVLALLRWRMVSLA
ADAGRAVILADRLTESLLAAPDGFYAWLGEREICSRRLAVLLGLFGGTESAFMDVLESFAAADAAQLDSAARRLREEGQG
FELELRLRDGGRRVRAVGVRACGPEGAALADLVWMHDVTEGAAFEAELASRLAGLVVERERIEGLLGVLPIPAWVRDDDL
SLLHVNRAYARAVDVASPLAAVAGQIELASDGSVREARALAARARAAGEPRSESFHLVLGGQRRFTEITEAPFEAEDGGL
LTAGYALDLTRVEELQQELARHASAHAQVLEHLATAIAIFSTDTRLTFFNTAFTRLWRLEAEWLAAQPTYGAVLDSLRER
RLLPEVADYRAYKEDELKRFISLIDAAETLLHLPDGRTLRRMIAAHPYGGLIFTYEDVTDTLALERSFNTALAVQRETLD
HLHEGVAVFKGDGRLRLFNPAYARIWNLAPSMLESEPHLNELVEAHRPYFEGGAERASVWPEMRERLMALFNTRAPQSGR
VERLDDSIVDFASVPLPDGAMLLTWLDVTDSARVERALRERNEALAAADLLKSEFIANVSAEVRKPLTTVIGFSEMLAAE
YFGKLNKRQHEYARGITEAGQGLQALISDILDLAAIEAGQMALELDTVDVHPMLSGVLGLVRERVREKKVTLDFDCPLDI
GWIVADERRLRQVLFNLLGNALKRTPSGGKVSVRAERRPSELALTISDTGTGLSDEQRERLFGGFATGGRREALPAGRAD
DDSGIGLALVQRFVDLHGGRVELASAPGEGTVVTVRLPVGSGAT
>Mature_843_residues
SFAPRIGTLGPLWGDDGMRAAFAAGLALMLAAGGAAAEEAPALASLRFDPLSLGIGALLVLVPALAVLALLRWRMVSLAA
DAGRAVILADRLTESLLAAPDGFYAWLGEREICSRRLAVLLGLFGGTESAFMDVLESFAAADAAQLDSAARRLREEGQGF
ELELRLRDGGRRVRAVGVRACGPEGAALADLVWMHDVTEGAAFEAELASRLAGLVVERERIEGLLGVLPIPAWVRDDDLS
LLHVNRAYARAVDVASPLAAVAGQIELASDGSVREARALAARARAAGEPRSESFHLVLGGQRRFTEITEAPFEAEDGGLL
TAGYALDLTRVEELQQELARHASAHAQVLEHLATAIAIFSTDTRLTFFNTAFTRLWRLEAEWLAAQPTYGAVLDSLRERR
LLPEVADYRAYKEDELKRFISLIDAAETLLHLPDGRTLRRMIAAHPYGGLIFTYEDVTDTLALERSFNTALAVQRETLDH
LHEGVAVFKGDGRLRLFNPAYARIWNLAPSMLESEPHLNELVEAHRPYFEGGAERASVWPEMRERLMALFNTRAPQSGRV
ERLDDSIVDFASVPLPDGAMLLTWLDVTDSARVERALRERNEALAAADLLKSEFIANVSAEVRKPLTTVIGFSEMLAAEY
FGKLNKRQHEYARGITEAGQGLQALISDILDLAAIEAGQMALELDTVDVHPMLSGVLGLVRERVREKKVTLDFDCPLDIG
WIVADERRLRQVLFNLLGNALKRTPSGGKVSVRAERRPSELALTISDTGTGLSDEQRERLFGGFATGGRREALPAGRADD
DSGIGLALVQRFVDLHGGRVELASAPGEGTVVTVRLPVGSGAT

Specific function: Required for cell division and growth. It catalyzes the phosphorylation of CtrA and activates transcription in vitro of the cell cycle-regulated fliF promoter [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=277, Percent_Identity=31.4079422382672, Blast_Score=125, Evalue=9e-30,
Organism=Escherichia coli, GI1789149, Length=227, Percent_Identity=30.8370044052863, Blast_Score=113, Evalue=6e-26,
Organism=Escherichia coli, GI1788393, Length=230, Percent_Identity=32.6086956521739, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI1786600, Length=267, Percent_Identity=30.7116104868914, Blast_Score=102, Evalue=7e-23,
Organism=Escherichia coli, GI145693157, Length=267, Percent_Identity=29.5880149812734, Blast_Score=102, Evalue=8e-23,
Organism=Escherichia coli, GI87081816, Length=237, Percent_Identity=30.8016877637131, Blast_Score=99, Evalue=1e-21,
Organism=Escherichia coli, GI1790436, Length=227, Percent_Identity=28.1938325991189, Blast_Score=96, Evalue=1e-20,
Organism=Escherichia coli, GI48994928, Length=259, Percent_Identity=27.7992277992278, Blast_Score=93, Evalue=9e-20,
Organism=Escherichia coli, GI1790861, Length=278, Percent_Identity=28.0575539568345, Blast_Score=89, Evalue=2e-18,
Organism=Escherichia coli, GI1788549, Length=249, Percent_Identity=27.710843373494, Blast_Score=86, Evalue=1e-17,
Organism=Escherichia coli, GI1786912, Length=231, Percent_Identity=27.7056277056277, Blast_Score=84, Evalue=4e-17,
Organism=Escherichia coli, GI87082128, Length=238, Percent_Identity=25.6302521008403, Blast_Score=77, Evalue=5e-15,
Organism=Escherichia coli, GI1786783, Length=227, Percent_Identity=27.7533039647577, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1790300, Length=276, Percent_Identity=24.2753623188406, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1789808, Length=228, Percent_Identity=26.7543859649123, Blast_Score=63, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 91607; Mature: 91475

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFAPRIGTLGPLWGDDGMRAAFAAGLALMLAAGGAAAEEAPALASLRFDPLSLGIGALL
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCHHHHHHHHHH
VLVPALAVLALLRWRMVSLAADAGRAVILADRLTESLLAAPDGFYAWLGEREICSRRLAV
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHH
LLGLFGGTESAFMDVLESFAAADAAQLDSAARRLREEGQGFELELRLRDGGRRVRAVGVR
HHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEEEE
ACGPEGAALADLVWMHDVTEGAAFEAELASRLAGLVVERERIEGLLGVLPIPAWVRDDDL
ECCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCC
SLLHVNRAYARAVDVASPLAAVAGQIELASDGSVREARALAARARAAGEPRSESFHLVLG
EEEEEHHHHHHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEC
GQRRFTEITEAPFEAEDGGLLTAGYALDLTRVEELQQELARHASAHAQVLEHLATAIAIF
CCHHHHHHHCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
STDTRLTFFNTAFTRLWRLEAEWLAAQPTYGAVLDSLRERRLLPEVADYRAYKEDELKRF
ECCCEEEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHH
ISLIDAAETLLHLPDGRTLRRMIAAHPYGGLIFTYEDVTDTLALERSFNTALAVQRETLD
HHHHHHHHHHHCCCCCHHHHHHHHCCCCCCEEEEECCHHHHHHHHHCCCHHHHHHHHHHH
HLHEGVAVFKGDGRLRLFNPAYARIWNLAPSMLESEPHLNELVEAHRPYFEGGAERASVW
HHHCCEEEEECCCEEEEECHHHHHHHHHCHHHHCCCCCHHHHHHHCCCHHCCCCHHHHCC
PEMRERLMALFNTRAPQSGRVERLDDSIVDFASVPLPDGAMLLTWLDVTDSARVERALRE
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHH
RNEALAAADLLKSEFIANVSAEVRKPLTTVIGFSEMLAAEYFGKLNKRQHEYARGITEAG
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
QGLQALISDILDLAAIEAGQMALELDTVDVHPMLSGVLGLVRERVREKKVTLDFDCPLDI
CCHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCC
GWIVADERRLRQVLFNLLGNALKRTPSGGKVSVRAERRPSELALTISDTGTGLSDEQRER
EEEEECHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEEEECCCCCCCHHHHHH
LFGGFATGGRREALPAGRADDDSGIGLALVQRFVDLHGGRVELASAPGEGTVVTVRLPVG
HHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEECCC
SGAT
CCCC
>Mature Secondary Structure 
SFAPRIGTLGPLWGDDGMRAAFAAGLALMLAAGGAAAEEAPALASLRFDPLSLGIGALL
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCHHHHHHHHHH
VLVPALAVLALLRWRMVSLAADAGRAVILADRLTESLLAAPDGFYAWLGEREICSRRLAV
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHH
LLGLFGGTESAFMDVLESFAAADAAQLDSAARRLREEGQGFELELRLRDGGRRVRAVGVR
HHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEEEE
ACGPEGAALADLVWMHDVTEGAAFEAELASRLAGLVVERERIEGLLGVLPIPAWVRDDDL
ECCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCC
SLLHVNRAYARAVDVASPLAAVAGQIELASDGSVREARALAARARAAGEPRSESFHLVLG
EEEEEHHHHHHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEC
GQRRFTEITEAPFEAEDGGLLTAGYALDLTRVEELQQELARHASAHAQVLEHLATAIAIF
CCHHHHHHHCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
STDTRLTFFNTAFTRLWRLEAEWLAAQPTYGAVLDSLRERRLLPEVADYRAYKEDELKRF
ECCCEEEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHH
ISLIDAAETLLHLPDGRTLRRMIAAHPYGGLIFTYEDVTDTLALERSFNTALAVQRETLD
HHHHHHHHHHHCCCCCHHHHHHHHCCCCCCEEEEECCHHHHHHHHHCCCHHHHHHHHHHH
HLHEGVAVFKGDGRLRLFNPAYARIWNLAPSMLESEPHLNELVEAHRPYFEGGAERASVW
HHHCCEEEEECCCEEEEECHHHHHHHHHCHHHHCCCCCHHHHHHHCCCHHCCCCHHHHCC
PEMRERLMALFNTRAPQSGRVERLDDSIVDFASVPLPDGAMLLTWLDVTDSARVERALRE
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHH
RNEALAAADLLKSEFIANVSAEVRKPLTTVIGFSEMLAAEYFGKLNKRQHEYARGITEAG
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
QGLQALISDILDLAAIEAGQMALELDTVDVHPMLSGVLGLVRERVREKKVTLDFDCPLDI
CCHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCC
GWIVADERRLRQVLFNLLGNALKRTPSGGKVSVRAERRPSELALTISDTGTGLSDEQRER
EEEEECHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEEEECCCCCCCHHHHHH
LFGGFATGGRREALPAGRADDDSGIGLALVQRFVDLHGGRVELASAPGEGTVVTVRLPVG
HHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEECCC
SGAT
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10557274; 11259647 [H]