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The map label for this gene is exoC [H]

Identifier: 83309672

GI number: 83309672

Start: 620062

End: 621444

Strand: Reverse

Name: exoC [H]

Synonym: amb0573

Alternate gene names: 83309672

Gene position: 621444-620062 (Counterclockwise)

Preceding gene: 83309673

Following gene: 83309671

Centisome position: 12.51

GC content: 68.47

Gene sequence:

>1383_bases
ATGACCCACATCTTCCACCCCACCATCCTGCGCGAATACGACATCCGCGGCATTATCGGCGAGACGCTGTTCGCCGCCGA
CGCCGAGGCCATCGGCCGGGCTTTCGGCACGCGGGTGCGCCGCAATGGCGGCCATGTGGTCTGTCTCGGCTGGGACGGTC
GCCTATCCAGCCCCGAGATGGCCGAGGCGCTGACCAAGGGCCTGATGGCGGCGGGCTGCACCGTGCGGCGTGTCGGGCGC
GGCCCCACCCCCATGCTGTATTTCGCCGCCAAGGTGCGGGACGCCGATGGCGGCATCATGGTGACGGGCAGCCACAACCC
GCCCAACCACAACGGCTTCAAGATGGTGCTGGCCGGCAGGCCGTTCTTCGGCCCCGACATCCAGTCGCTGGGGACCATCG
CCGCTGCCGGCGACTTCGCCAGCGGCGAGGGCAAGGCCGTCGAGGATTCGGTGTTCGAGGAATACGTGTCCCGCCTGGCC
CAGGATTATGACGGCCTGCGCGACCTGCGGGTAGTGTGGGATTGCGGCAACGGCGCCACCGGCGAGGTGCTGCACGCCTT
GGTCAAGCGCCTGCCCGGCACCCATACCGTGCTGTTCGGCGAGATCGACGGGCATTTCCCCAATCACCACCCCGACCCCA
CCGAGCCCCACAATCTGGTGGCGCTGCAGGACAAGGTGCTGACCGAATCCGCCCATCTGGGCATCGCCTTCGACGGCGAC
GGCGACCGCATCGGCGTGGTGGATGCCGAGGGCCGCATCCTCTACGGCGACCAGATCCTGGTGATCCTGGCCGAGGATCT
GCTGAAATCCCTGCCCGGCGCCACCATCATCGCCGACGTCAAGGCCTCCAAGGTGTTCTTCGACGAGGTGCGCCGCATGG
GCGGCAACGCCGTCATGGGCCGCACCGGCCATTCACTGATTAAGACCCAGATGGCCGAGACCGGCGCCCCCCTGGCCGGC
GAGATGAGCGGCCACATCTTCTTCGCCGACCGCTATTACGGCTTCGACGACGCCCTTTACGCCGCCATCCGCCTGCTGGG
CATCGTGGCGCGCTGGGATCACACGACCATCGGCCAGCGCCGCGACAGGCTGCCCCACATGGTCAACACCCCGGAACTGC
GCTTCGACTGCCCGGAGGAGCGAAAGTTCGCCGTGGTGGCCGAGGTGAAAGCCCGTCTGGAGGCCGAGGGCGCCAGCTTC
TCAGCCATCGACGGCGTGCGGGTGGATACCCCGGACGGCTGGTGGCTGCTGCGCGCCTCCAACACCCAGGCGGTGCTGGT
GGCCCGTTGCGAGGCGGCCAGTTCCGAGGGGCTCAAGCACCTGCGCCAGACCCTGGCCGACCAGCTGGCGGCCAGCGGGG
TGAGTCTGGGGCATACCCACTGA

Upstream 100 bases:

>100_bases
GACCCCCAGGTGGCCCTGGCCGACCTCATCACAATCGCCCGCGACCTGGCCCAGATCGAGGCCCGGACCGGACGGACCGA
ACCGACGGTGATTACCTGAC

Downstream 100 bases:

>100_bases
TGGTGGCTTGAAATTCCCCCGGTTCGCCTCCAGACTAATATTATTCGAAGGTAGGGGGTCGGGGACCGGTCTCCCCTCCG
CAATAATTCAATAGCCAAGA

Product: phosphomannomutase

Products: NA

Alternate protein names: PMM [H]

Number of amino acids: Translated: 460; Mature: 459

Protein sequence:

>460_residues
MTHIFHPTILREYDIRGIIGETLFAADAEAIGRAFGTRVRRNGGHVVCLGWDGRLSSPEMAEALTKGLMAAGCTVRRVGR
GPTPMLYFAAKVRDADGGIMVTGSHNPPNHNGFKMVLAGRPFFGPDIQSLGTIAAAGDFASGEGKAVEDSVFEEYVSRLA
QDYDGLRDLRVVWDCGNGATGEVLHALVKRLPGTHTVLFGEIDGHFPNHHPDPTEPHNLVALQDKVLTESAHLGIAFDGD
GDRIGVVDAEGRILYGDQILVILAEDLLKSLPGATIIADVKASKVFFDEVRRMGGNAVMGRTGHSLIKTQMAETGAPLAG
EMSGHIFFADRYYGFDDALYAAIRLLGIVARWDHTTIGQRRDRLPHMVNTPELRFDCPEERKFAVVAEVKARLEAEGASF
SAIDGVRVDTPDGWWLLRASNTQAVLVARCEAASSEGLKHLRQTLADQLAASGVSLGHTH

Sequences:

>Translated_460_residues
MTHIFHPTILREYDIRGIIGETLFAADAEAIGRAFGTRVRRNGGHVVCLGWDGRLSSPEMAEALTKGLMAAGCTVRRVGR
GPTPMLYFAAKVRDADGGIMVTGSHNPPNHNGFKMVLAGRPFFGPDIQSLGTIAAAGDFASGEGKAVEDSVFEEYVSRLA
QDYDGLRDLRVVWDCGNGATGEVLHALVKRLPGTHTVLFGEIDGHFPNHHPDPTEPHNLVALQDKVLTESAHLGIAFDGD
GDRIGVVDAEGRILYGDQILVILAEDLLKSLPGATIIADVKASKVFFDEVRRMGGNAVMGRTGHSLIKTQMAETGAPLAG
EMSGHIFFADRYYGFDDALYAAIRLLGIVARWDHTTIGQRRDRLPHMVNTPELRFDCPEERKFAVVAEVKARLEAEGASF
SAIDGVRVDTPDGWWLLRASNTQAVLVARCEAASSEGLKHLRQTLADQLAASGVSLGHTH
>Mature_459_residues
THIFHPTILREYDIRGIIGETLFAADAEAIGRAFGTRVRRNGGHVVCLGWDGRLSSPEMAEALTKGLMAAGCTVRRVGRG
PTPMLYFAAKVRDADGGIMVTGSHNPPNHNGFKMVLAGRPFFGPDIQSLGTIAAAGDFASGEGKAVEDSVFEEYVSRLAQ
DYDGLRDLRVVWDCGNGATGEVLHALVKRLPGTHTVLFGEIDGHFPNHHPDPTEPHNLVALQDKVLTESAHLGIAFDGDG
DRIGVVDAEGRILYGDQILVILAEDLLKSLPGATIIADVKASKVFFDEVRRMGGNAVMGRTGHSLIKTQMAETGAPLAGE
MSGHIFFADRYYGFDDALYAAIRLLGIVARWDHTTIGQRRDRLPHMVNTPELRFDCPEERKFAVVAEVKARLEAEGASFS
AIDGVRVDTPDGWWLLRASNTQAVLVARCEAASSEGLKHLRQTLADQLAASGVSLGHTH

Specific function: Involved In The Biosynthesis Of The Capsular Polysaccharide Colanic Acid. [C]

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Escherichia coli, GI1788361, Length=438, Percent_Identity=33.5616438356164, Blast_Score=193, Evalue=2e-50,
Organism=Escherichia coli, GI1789566, Length=465, Percent_Identity=27.3118279569892, Blast_Score=109, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.8 [H]

Molecular weight: Translated: 49704; Mature: 49573

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHIFHPTILREYDIRGIIGETLFAADAEAIGRAFGTRVRRNGGHVVCLGWDGRLSSPEM
CCCCCCCHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHH
AEALTKGLMAAGCTVRRVGRGPTPMLYFAAKVRDADGGIMVTGSHNPPNHNGFKMVLAGR
HHHHHHHHHHCCCHHEECCCCCCCEEEEEEEEEECCCCEEEECCCCCCCCCCEEEEEECC
PFFGPDIQSLGTIAAAGDFASGEGKAVEDSVFEEYVSRLAQDYDGLRDLRVVWDCGNGAT
CCCCCCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCH
GEVLHALVKRLPGTHTVLFGEIDGHFPNHHPDPTEPHNLVALQDKVLTESAHLGIAFDGD
HHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEHHHHHCCCCCEEEEECCC
GDRIGVVDAEGRILYGDQILVILAEDLLKSLPGATIIADVKASKVFFDEVRRMGGNAVMG
CCEEEEEECCCEEEECCCEEEEEHHHHHHHCCCCEEEEECHHHHHHHHHHHHCCCCEEEC
RTGHSLIKTQMAETGAPLAGEMSGHIFFADRYYGFDDALYAAIRLLGIVARWDHTTIGQR
CCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHH
RDRLPHMVNTPELRFDCPEERKFAVVAEVKARLEAEGASFSAIDGVRVDTPDGWWLLRAS
HHCCCCCCCCCCEEECCCCCCCEEEEEHHHHHHHCCCCCEEEECCEEEECCCCEEEEEEC
NTQAVLVARCEAASSEGLKHLRQTLADQLAASGVSLGHTH
CCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
THIFHPTILREYDIRGIIGETLFAADAEAIGRAFGTRVRRNGGHVVCLGWDGRLSSPEM
CCCCCCHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHH
AEALTKGLMAAGCTVRRVGRGPTPMLYFAAKVRDADGGIMVTGSHNPPNHNGFKMVLAGR
HHHHHHHHHHCCCHHEECCCCCCCEEEEEEEEEECCCCEEEECCCCCCCCCCEEEEEECC
PFFGPDIQSLGTIAAAGDFASGEGKAVEDSVFEEYVSRLAQDYDGLRDLRVVWDCGNGAT
CCCCCCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCH
GEVLHALVKRLPGTHTVLFGEIDGHFPNHHPDPTEPHNLVALQDKVLTESAHLGIAFDGD
HHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEHHHHHCCCCCEEEEECCC
GDRIGVVDAEGRILYGDQILVILAEDLLKSLPGATIIADVKASKVFFDEVRRMGGNAVMG
CCEEEEEECCCEEEECCCEEEEEHHHHHHHCCCCEEEEECHHHHHHHHHHHHCCCCEEEC
RTGHSLIKTQMAETGAPLAGEMSGHIFFADRYYGFDDALYAAIRLLGIVARWDHTTIGQR
CCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHH
RDRLPHMVNTPELRFDCPEERKFAVVAEVKARLEAEGASFSAIDGVRVDTPDGWWLLRAS
HHCCCCCCCCCCEEECCCCCCCEEEEEHHHHHHHCCCCCEEEECCEEEECCCCEEEEEEC
NTQAVLVARCEAASSEGLKHLRQTLADQLAASGVSLGHTH
CCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA