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The map label for this gene is nixA [H]

Identifier: 82752276

GI number: 82752276

Start: 2727799

End: 2728815

Strand: Direct

Name: nixA [H]

Synonym: SAB2574

Alternate gene names: 82752276

Gene position: 2727799-2728815 (Clockwise)

Preceding gene: 82752275

Following gene: 82752277

Centisome position: 99.46

GC content: 34.22

Gene sequence:

>1017_bases
TTGACTGTTTTTAAAAATGAGCGCTTAAGCTGGTTACCATACATAGCTATTGTCATTTTGTTACACGTTATTGGGTTTAG
TTTTTTATGGATTGCTGGAAAAGACCATCATATCTTATTTGGTATGGGGATTCTTGCATATACATTAGGTTTACGTCATG
CATTTGATGCTGATCATATCGCCGCGATAGATAATACGGTTCGCAAATTATTACAGCAACGCAAAGATCCATCTGGTGTT
GGTTTCTACTTTTCAATTGGACATTCATCTGTCGTATTTTTAATGGCTGTTTTTTTAGGGGTATCTGTAAAATGGGCTAA
AGATGAATTACCACATTTCCAAGATATTGGTGGAACGATTGGTACATTAGTTTCAGGTTTCTTTTTAGTGCTTATCGGTG
TGTTGAATCTAATTATTTTAATCTCTTTAATTAACTTATTCGCTAAATTACGTCGTGAACACATTGAAGAAGCTGAAGTC
GATGCATTACTTGAATCTAGAGGATTTGTTTCTCGATTTGTAGGACCTTATTTCAAATTAATCACGCGTAGTTGGCACGT
ATTGCCACTTGGCTTTTTATTTGGACTTGGTTTTGATACAGCTAGTGAAATTGCGTTACTCGCTCTTTCTTCAGGCGCAT
CACAACAAGCCATTTCATTTATCGGAATCTTATCTTTACCAATTTTATTCGCATCAGGTATGAGTTTGTTGGATACTTTA
GATGGTGTTGTAATGAAATATGCCTATAATTGGGCATTCTTCAATCCTATTCGCAAAATCTATTACAATATAACGATTAC
TGCGATATCCGTCATAGCTGCATTAGTGATTGGGATGATTGAATTGCTACAAATTCTTGCTGATAAACTAGACTTACATG
GTGCATTTTGGGCATTTATTAGTTCAATCGAATTTGATTATTTAGGTTATATTCTAGTTGCTTTATTTTTAATTACTTGG
CTTATTTCAAGTTTAATTTGGAAGTTTGGTCGCATAGAACACAAATGGTCTAAATAA

Upstream 100 bases:

>100_bases
TAATTTTGTATAACATTTTTGTTATATGAACACTTATTATTAGAGTGCACATTGAACATACAGTATGATTAAATATCATG
TTATGAAAGAAGGATATATT

Downstream 100 bases:

>100_bases
AGTAACTTGTCTTGCAACTACCTTTGTATTGTTACATTTTTAGACATCCTGCACACTTCTTCCATTATGCTACGCTCTCA
GTAGTCATCTTTAAATCGTT

Product: high-affinity nickel-transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MTVFKNERLSWLPYIAIVILLHVIGFSFLWIAGKDHHILFGMGILAYTLGLRHAFDADHIAAIDNTVRKLLQQRKDPSGV
GFYFSIGHSSVVFLMAVFLGVSVKWAKDELPHFQDIGGTIGTLVSGFFLVLIGVLNLIILISLINLFAKLRREHIEEAEV
DALLESRGFVSRFVGPYFKLITRSWHVLPLGFLFGLGFDTASEIALLALSSGASQQAISFIGILSLPILFASGMSLLDTL
DGVVMKYAYNWAFFNPIRKIYYNITITAISVIAALVIGMIELLQILADKLDLHGAFWAFISSIEFDYLGYILVALFLITW
LISSLIWKFGRIEHKWSK

Sequences:

>Translated_338_residues
MTVFKNERLSWLPYIAIVILLHVIGFSFLWIAGKDHHILFGMGILAYTLGLRHAFDADHIAAIDNTVRKLLQQRKDPSGV
GFYFSIGHSSVVFLMAVFLGVSVKWAKDELPHFQDIGGTIGTLVSGFFLVLIGVLNLIILISLINLFAKLRREHIEEAEV
DALLESRGFVSRFVGPYFKLITRSWHVLPLGFLFGLGFDTASEIALLALSSGASQQAISFIGILSLPILFASGMSLLDTL
DGVVMKYAYNWAFFNPIRKIYYNITITAISVIAALVIGMIELLQILADKLDLHGAFWAFISSIEFDYLGYILVALFLITW
LISSLIWKFGRIEHKWSK
>Mature_337_residues
TVFKNERLSWLPYIAIVILLHVIGFSFLWIAGKDHHILFGMGILAYTLGLRHAFDADHIAAIDNTVRKLLQQRKDPSGVG
FYFSIGHSSVVFLMAVFLGVSVKWAKDELPHFQDIGGTIGTLVSGFFLVLIGVLNLIILISLINLFAKLRREHIEEAEVD
ALLESRGFVSRFVGPYFKLITRSWHVLPLGFLFGLGFDTASEIALLALSSGASQQAISFIGILSLPILFASGMSLLDTLD
GVVMKYAYNWAFFNPIRKIYYNITITAISVIAALVIGMIELLQILADKLDLHGAFWAFISSIEFDYLGYILVALFLITWL
ISSLIWKFGRIEHKWSK

Specific function: High-affinity nickel intake protein. Imports nickel ions in an energy-dependent fashion. Necessary for the expression of catalytically active urease [H]

COG id: COG3376

COG function: function code P; High-affinity nickel permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NiCoT transporter (TC 2.A.52) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004688
- InterPro:   IPR011541 [H]

Pfam domain/function: PF03824 NicO [H]

EC number: NA

Molecular weight: Translated: 37848; Mature: 37717

Theoretical pI: Translated: 8.03; Mature: 8.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVFKNERLSWLPYIAIVILLHVIGFSFLWIAGKDHHILFGMGILAYTLGLRHAFDADHI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHCCCHHH
AAIDNTVRKLLQQRKDPSGVGFYFSIGHSSVVFLMAVFLGVSVKWAKDELPHFQDIGGTI
HHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHCCCCEEHHHCCCCHHHHCHHH
GTLVSGFFLVLIGVLNLIILISLINLFAKLRREHIEEAEVDALLESRGFVSRFVGPYFKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
ITRSWHVLPLGFLFGLGFDTASEIALLALSSGASQQAISFIGILSLPILFASGMSLLDTL
HHCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHH
DGVVMKYAYNWAFFNPIRKIYYNITITAISVIAALVIGMIELLQILADKLDLHGAFWAFI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSIEFDYLGYILVALFLITWLISSLIWKFGRIEHKWSK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TVFKNERLSWLPYIAIVILLHVIGFSFLWIAGKDHHILFGMGILAYTLGLRHAFDADHI
CCCCCCCCHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHCCCHHH
AAIDNTVRKLLQQRKDPSGVGFYFSIGHSSVVFLMAVFLGVSVKWAKDELPHFQDIGGTI
HHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHCCCCEEHHHCCCCHHHHCHHH
GTLVSGFFLVLIGVLNLIILISLINLFAKLRREHIEEAEVDALLESRGFVSRFVGPYFKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
ITRSWHVLPLGFLFGLGFDTASEIALLALSSGASQQAISFIGILSLPILFASGMSLLDTL
HHCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHH
DGVVMKYAYNWAFFNPIRKIYYNITITAISVIAALVIGMIELLQILADKLDLHGAFWAFI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSIEFDYLGYILVALFLITWLISSLIWKFGRIEHKWSK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]