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The map label for this gene is pcp

Identifier: 82752268

GI number: 82752268

Start: 2721375

End: 2722013

Strand: Direct

Name: pcp

Synonym: SAB2566

Alternate gene names: 82752268

Gene position: 2721375-2722013 (Clockwise)

Preceding gene: 82752267

Following gene: 82752271

Centisome position: 99.23

GC content: 37.09

Gene sequence:

>639_bases
ATGCACATTTTAGTAACAGGGTTTGCGCCTTTTGACAATCAAGATATTAATCCTTCTTGGGAAGCTGTGACTCAACTAGA
AGATATTATTGGCACACATACAATCGATAAACTAAAACTACCAACCTCTTTTAAGAAAGTAGATACTATGATAAATAAAG
CATTAGCATCTAATCACTATGATATTGTGTTATCGATAGGACAAGCTGGTGGGAGAAGTGCCATCACACCAGAACGTGTT
GCTATAAATATTGATGATGCGCGTATTCCAGATAATGATGATTTTCAACCTATTGATCAAGCCATTCACTTAGACGGTGC
GCCAGCTTATTTTTCAAATTTACCAGTTAAAGCAATGACTCAAAGTATTATTAACCAAGGACTTCCTGGAGCACTTTCAA
ATAGCGCAGGTACGTTCGTATGTAATCACGTACTTTATCACTTAGGTTATTTACAAGATAAGCATTACCCTCTTCTTCGA
TTCGGATTTATTCATGTGCCATACATACCAGAGCAGATTGATGGTAAATCCGATACACCATCAATGACATTAGAAAACAT
TGTTACAGGGCTGACTGCAGCTATTGAAGCTATTTCTGATGACGATGATTTACGTATAGCTCTAGGCACAACAGAATAG

Upstream 100 bases:

>100_bases
TTTTTCAAGGCTGTTTTTTATGCGCGTACATAACCTGATATGTTTTTAATTATGCGCATGTTATACTAAATTAAATTTTA
ATACTGCGGGGTGTCTTAAA

Downstream 100 bases:

>100_bases
TTAAAAGTACACAAACAAAAGCACCCTAATTTGTTAGTTTAAGTCTAACTTTAGGGTGCTTTTGGATGATTGGTATACAG
TTTTACTATAATGATGTATT

Product: pyrrolidone-carboxylate peptidase

Products: NA

Alternate protein names: 5-oxoprolyl-peptidase; Pyroglutamyl-peptidase I; PGP-I; Pyrase [H]

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MHILVTGFAPFDNQDINPSWEAVTQLEDIIGTHTIDKLKLPTSFKKVDTMINKALASNHYDIVLSIGQAGGRSAITPERV
AINIDDARIPDNDDFQPIDQAIHLDGAPAYFSNLPVKAMTQSIINQGLPGALSNSAGTFVCNHVLYHLGYLQDKHYPLLR
FGFIHVPYIPEQIDGKSDTPSMTLENIVTGLTAAIEAISDDDDLRIALGTTE

Sequences:

>Translated_212_residues
MHILVTGFAPFDNQDINPSWEAVTQLEDIIGTHTIDKLKLPTSFKKVDTMINKALASNHYDIVLSIGQAGGRSAITPERV
AINIDDARIPDNDDFQPIDQAIHLDGAPAYFSNLPVKAMTQSIINQGLPGALSNSAGTFVCNHVLYHLGYLQDKHYPLLR
FGFIHVPYIPEQIDGKSDTPSMTLENIVTGLTAAIEAISDDDDLRIALGTTE
>Mature_212_residues
MHILVTGFAPFDNQDINPSWEAVTQLEDIIGTHTIDKLKLPTSFKKVDTMINKALASNHYDIVLSIGQAGGRSAITPERV
AINIDDARIPDNDDFQPIDQAIHLDGAPAYFSNLPVKAMTQSIINQGLPGALSNSAGTFVCNHVLYHLGYLQDKHYPLLR
FGFIHVPYIPEQIDGKSDTPSMTLENIVTGLTAAIEAISDDDDLRIALGTTE

Specific function: Removes 5-oxoproline from various penultimate amino acid residues except L-proline [H]

COG id: COG2039

COG function: function code O; Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C15 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000816
- InterPro:   IPR016125 [H]

Pfam domain/function: PF01470 Peptidase_C15 [H]

EC number: =3.4.19.3 [H]

Molecular weight: Translated: 23152; Mature: 23152

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: PS01333 PYRASE_GLU ; PS01334 PYRASE_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHILVTGFAPFDNQDINPSWEAVTQLEDIIGTHTIDKLKLPTSFKKVDTMINKALASNHY
CEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCHHHEECCCHHHHHHHHHHHHHHCCCC
DIVLSIGQAGGRSAITPERVAINIDDARIPDNDDFQPIDQAIHLDGAPAYFSNLPVKAMT
EEEEEECCCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHEECCCCCHHHHCCCHHHHH
QSIINQGLPGALSNSAGTFVCNHVLYHLGYLQDKHYPLLRFGFIHVPYIPEQIDGKSDTP
HHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECEEECCCCCHHCCCCCCCC
SMTLENIVTGLTAAIEAISDDDDLRIALGTTE
CHHHHHHHHHHHHHHHHCCCCCCEEEEEECCC
>Mature Secondary Structure
MHILVTGFAPFDNQDINPSWEAVTQLEDIIGTHTIDKLKLPTSFKKVDTMINKALASNHY
CEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCHHHEECCCHHHHHHHHHHHHHHCCCC
DIVLSIGQAGGRSAITPERVAINIDDARIPDNDDFQPIDQAIHLDGAPAYFSNLPVKAMT
EEEEEECCCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHEECCCCCHHHHCCCHHHHH
QSIINQGLPGALSNSAGTFVCNHVLYHLGYLQDKHYPLLRFGFIHVPYIPEQIDGKSDTP
HHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECEEECCCCCHHCCCCCCCC
SMTLENIVTGLTAAIEAISDDDDLRIALGTTE
CHHHHHHHHHHHHHHHHCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA