Click here to switch to the map view.

The map label for this gene is panC

Identifier: 82752178

GI number: 82752178

Start: 2607338

End: 2608189

Strand: Reverse

Name: panC

Synonym: SAB2471c

Alternate gene names: 82752178

Gene position: 2608189-2607338 (Counterclockwise)

Preceding gene: 82752179

Following gene: 82752177

Centisome position: 95.1

GC content: 36.62

Gene sequence:

>852_bases
ATGACTAAGCTGATTACTACGGTAAAAGAGATGCAACACATTGTTAAAGCAGCCAAACGCTCAGGCACAACGATTGGTTT
GATCCCAACAATGGGTGCCTTACATGATGGACATTTAACGATGGTACGCGAATCAGTTAGTACAAATGATATTACAGTTG
TGAGTGTATTTGTTAATCCATTACAATTTGGTCCAAACGAAGATTTCGATGCTTATCCGAGACAAATTGATAAAGATTTA
GAATTAGTATCAGAAGTAGGGGCGGACATTGTTTTTCATCCTGCAGTAGAAGATATGTATCCAGGTGAATTAGGTATTGA
TGTCAAAGTAGGTCCATTAGCTGATGTGTTAGAAGGAGCGAAGCGTCCAGGGCATTTTGATGGGGTGGTAACAGTAGTTA
ATAAGCTATTTAATATTGTTATGCCGGATTATGCTTATTTTGGTAAAAAAGATGCCCAGCAATTGGCTATTGTCGAGCAA
ATGGTAAAAGACTTCAATCATGCCGTTGAAATTATTGGTATTGATATCGTTCGAGAAGCAGATGGTTTGGCGAAAAGTTC
AAGAAATGTTTATTTAACGGAGCAAGAACGACAAGAAGCGGTACATTTAAGTAAAAGTTTGCTATTAGCACAAGCGTTGT
ATCAAGACGGTGAACGTCAAAGTAAAGTAATTATAGACAGGGTTACTCAATATCTTGAATCACATATAAGTGGACGCATT
GAAGAAGTTGCTGTTTATAGTTATCCTCAATTAGTAGAACAACACGAAATAACTGGACGCATATTTATCTCGTTAGCTGT
CAAATTTTCAAAAGCGCGTTTAATAGATAATATAATAATTGGAGCTGAATAA

Upstream 100 bases:

>100_bases
GTGGATGGTTTAAAACAATACGATCAAGAAGTTAAATCTGGTGCATTTCCATCAGAAGAATATACGTATAAAAAGAAAAT
TATGAATGAGGTTAATAACA

Downstream 100 bases:

>100_bases
AGTGATAAGAACAATGATGAATGCTAAAATTCATAGAGCAAGAGTGACTGAGTCAAATTTAAATTATGTAGGTAGCATTA
CGATTGATTCAGATATATTG

Product: pantoate--beta-alanine ligase

Products: NA

Alternate protein names: PS; Pantoate--beta-alanine ligase; Pantoate-activating enzyme [H]

Number of amino acids: Translated: 283; Mature: 282

Protein sequence:

>283_residues
MTKLITTVKEMQHIVKAAKRSGTTIGLIPTMGALHDGHLTMVRESVSTNDITVVSVFVNPLQFGPNEDFDAYPRQIDKDL
ELVSEVGADIVFHPAVEDMYPGELGIDVKVGPLADVLEGAKRPGHFDGVVTVVNKLFNIVMPDYAYFGKKDAQQLAIVEQ
MVKDFNHAVEIIGIDIVREADGLAKSSRNVYLTEQERQEAVHLSKSLLLAQALYQDGERQSKVIIDRVTQYLESHISGRI
EEVAVYSYPQLVEQHEITGRIFISLAVKFSKARLIDNIIIGAE

Sequences:

>Translated_283_residues
MTKLITTVKEMQHIVKAAKRSGTTIGLIPTMGALHDGHLTMVRESVSTNDITVVSVFVNPLQFGPNEDFDAYPRQIDKDL
ELVSEVGADIVFHPAVEDMYPGELGIDVKVGPLADVLEGAKRPGHFDGVVTVVNKLFNIVMPDYAYFGKKDAQQLAIVEQ
MVKDFNHAVEIIGIDIVREADGLAKSSRNVYLTEQERQEAVHLSKSLLLAQALYQDGERQSKVIIDRVTQYLESHISGRI
EEVAVYSYPQLVEQHEITGRIFISLAVKFSKARLIDNIIIGAE
>Mature_282_residues
TKLITTVKEMQHIVKAAKRSGTTIGLIPTMGALHDGHLTMVRESVSTNDITVVSVFVNPLQFGPNEDFDAYPRQIDKDLE
LVSEVGADIVFHPAVEDMYPGELGIDVKVGPLADVLEGAKRPGHFDGVVTVVNKLFNIVMPDYAYFGKKDAQQLAIVEQM
VKDFNHAVEIIGIDIVREADGLAKSSRNVYLTEQERQEAVHLSKSLLLAQALYQDGERQSKVIIDRVTQYLESHISGRIE
EVAVYSYPQLVEQHEITGRIFISLAVKFSKARLIDNIIIGAE

Specific function: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate [H]

COG id: COG0414

COG function: function code H; Panthothenate synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pantothenate synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786325, Length=279, Percent_Identity=41.9354838709677, Blast_Score=212, Evalue=2e-56,
Organism=Saccharomyces cerevisiae, GI6322046, Length=289, Percent_Identity=39.7923875432526, Blast_Score=184, Evalue=1e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003721
- InterPro:   IPR014729 [H]

Pfam domain/function: PF02569 Pantoate_ligase [H]

EC number: =6.3.2.1 [H]

Molecular weight: Translated: 31413; Mature: 31282

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKLITTVKEMQHIVKAAKRSGTTIGLIPTMGALHDGHLTMVRESVSTNDITVVSVFVNP
CCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHCCCCCEEEEEEEECH
LQFGPNEDFDAYPRQIDKDLELVSEVGADIVFHPAVEDMYPGELGIDVKVGPLADVLEGA
HHCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCHHHCCCCCCCCEEEECCHHHHHHCC
KRPGHFDGVVTVVNKLFNIVMPDYAYFGKKDAQQLAIVEQMVKDFNHAVEIIGIDIVREA
CCCCCCHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DGLAKSSRNVYLTEQERQEAVHLSKSLLLAQALYQDGERQSKVIIDRVTQYLESHISGRI
HHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCH
EEVAVYSYPQLVEQHEITGRIFISLAVKFSKARLIDNIIIGAE
HHHHHHCCHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHEECCC
>Mature Secondary Structure 
TKLITTVKEMQHIVKAAKRSGTTIGLIPTMGALHDGHLTMVRESVSTNDITVVSVFVNP
CHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHCCCCCEEEEEEEECH
LQFGPNEDFDAYPRQIDKDLELVSEVGADIVFHPAVEDMYPGELGIDVKVGPLADVLEGA
HHCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCHHHCCCCCCCCEEEECCHHHHHHCC
KRPGHFDGVVTVVNKLFNIVMPDYAYFGKKDAQQLAIVEQMVKDFNHAVEIIGIDIVREA
CCCCCCHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DGLAKSSRNVYLTEQERQEAVHLSKSLLLAQALYQDGERQSKVIIDRVTQYLESHISGRI
HHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCH
EEVAVYSYPQLVEQHEITGRIFISLAVKFSKARLIDNIIIGAE
HHHHHHCCHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA