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The map label for this gene is glcB

Identifier: 82752121

GI number: 82752121

Start: 2546308

End: 2548374

Strand: Reverse

Name: glcB

Synonym: SAB2412c

Alternate gene names: 82752121

Gene position: 2548374-2546308 (Counterclockwise)

Preceding gene: 82752122

Following gene: 82752120

Centisome position: 92.92

GC content: 36.53

Gene sequence:

>2067_bases
ATGTTTAAGAAATTGTTTGGACAATTGCAACGTATCGGTAAAGCATTAATGTTACCTGTTGCGATTTTACCAGCAGCTGG
TATTTTATTAGCGTTTGGTAACGCAATGCACAACGAACAATTAGTAGAAATTGCACCATGGTTAAAAAACGATATCATTG
TAATGATTTCGTCGGTCATGGAAGCATCAGGACAAGTTGTATTTGATAACTTGCCATTATTATTTGCAGTTGGTACAGCA
CTTGGATTAGCAGGAGGAGACGGTGTTGCAGCATTAGCAGCGCTAGTAGGTTACTTAATTATGAATGCAACAATGGGGAA
AGTGTTGCACATTACAATTGATGACATTTTCTCATATGCCAAAGGGGCAAAAGAATTAAGTCAAGCAGCGAAAGAACCAG
CACATGCCTTAGTATTAGGTATTCCAACGTTACAAACGGGTGTGTTTGGTGGTATTATCATGGGTGCTTTAGCCGCATGG
TGTTACAACAAATTTTATAATATTACACTACCACCATTTTTAGGATTCTTTGCAGGTAAACGATTTGTACCGATTGTGAC
ATCGGTCGTAGCAATTGCAACAGGTGTGGTTTTAAGCTTTGCGTGGCCACCAATTCAAGACGGATTAAATAGTTTATCGA
ATTTCTTATTAAATAAAAATTTAACATTAACAACGTTTATATTCGGTATTATTGAACGCTCATTAATTCCATTTGGTTTA
CATCATATTTTCTATTCACCGTTCTGGTTTGAATTCGGAAGTTATACAAATCACGCAGGTGAATTAGTTCGTGGTGACCA
ACGTATTTGGATGGCACAATTGAGAGATGGCGTACCATTTACTGCTGGTGCATTTACTACTGGTAAATATCCATTCATGA
TGTTTGGTTTACCAGCGGCAGCATTTGCTATTTATAAAAATGCACGACCAGAACGTAAAAAAGTCGTGGGTGGTTTAATG
TTATCAGCAGGATTAACTGCATTTTTAACTGGTATCACTGAGCCATTAGAATTTTCATTCTTATTTGTAGCACCAGTACT
TTATGGAATTCACGTATTATTAGCTGGTACATCATTCTTAGTAATGCATTTATTAGGCGTTAAAATTGGTATGACATTCT
CAGGTGGTTTCATAGATTATATTTTATATGGTTTATTAAACTGGGATCGTTCACACGCATTATTAGTTATTCCAGTCGGT
ATTGTATATGCTATCGTGTATTACTTCTTATTCGACTTTGCAATTCGTAAGTTTAAATTGAAAACACCAGGTCGTGAAGA
TGAAGAAACTGAAATTCGTAACTCTAGTGTCGCAAAATTACCATTTGATGTCTTAGATGCAATGGGTGGAAAAGAAAATA
TTAAACATTTAGATGCATGTATTACACGTCTGCGCGTAGAAGTGGTTGATAAATCAAAAGTAGATGTAGCAGGTATTAAA
GCTTTAGGCGCATCAGGTGTATTAGAAGTTGGAAACAATATGCAAGCTATCTTTGGTCCAAAATCAGATCAAATTAAACA
TGATATGGCCAAGATTATGAGTGGTGAAATTACGAAACCAAGTGAAACGACAGTGACTGAAGAAATGTCAGATGAACCAG
TTCACGTAGAAGCACTTGGAACAACAGACATCTATGCACCAGGTGTCGGTCAAATCATTCCATTATCAGAAGTACCTGAT
CAAGTATTCGCTGGTAAAATGATGGGTGATGGTGTTGGCTTTATCCCTGAAAAAGGTGAAATTGTAGCACCGTTTGATGG
TACAGTGAAAACAATCTTCCCTACGAAACATGCGATAGGATTAGAATCTGGAAGTGGTGTCGAAGTACTTATTCATATTG
GTATCGATACAGTGAAACTGAATGGTGAAGGATTCGAAAGTTTGATTAACGTTGATGAAAAAGTAACACAAGGTCAACCA
TTAATGAAAGTGAATTTAGCATACTTGAAAGCGCACGCACCAAGCATCGTTACACCAATGATTATTACAAATCTTGAAAA
TAAAGAACTTGTCATTGAAGATGTACAAGATGCTGATCCAGGTAAGCTAATTATGACAGTCAAATAA

Upstream 100 bases:

>100_bases
ATGCAGGCATGAGCAAACAACCGTACTATGAGAATAGTCTTGTTTGTTCATGCCTGCTTTTTTGTACATGGAAGCGGAAA
TTGAGATAGGGGATGTTTAT

Downstream 100 bases:

>100_bases
TGATTAAAAATGAAATAGCATATCAAATGAATGAACTTTTAGTCATTCGTAGTGCGTATGCGAAGTAGCGAGTTGAAAGA
GAATACGTTACAAAAGGCAG

Product: PTS system glucose-specific IIABC component

Products: NA

Alternate protein names: Glucoside permease IIC component; PTS system glucoside-specific EIIC component; Glucoside-specific phosphotransferase enzyme IIB component; PTS system glucoside-specific EIIB component; Glucoside-specific phosphotransferase enzyme IIA component; PTS system glucoside-specific EIIA component [H]

Number of amino acids: Translated: 688; Mature: 688

Protein sequence:

>688_residues
MFKKLFGQLQRIGKALMLPVAILPAAGILLAFGNAMHNEQLVEIAPWLKNDIIVMISSVMEASGQVVFDNLPLLFAVGTA
LGLAGGDGVAALAALVGYLIMNATMGKVLHITIDDIFSYAKGAKELSQAAKEPAHALVLGIPTLQTGVFGGIIMGALAAW
CYNKFYNITLPPFLGFFAGKRFVPIVTSVVAIATGVVLSFAWPPIQDGLNSLSNFLLNKNLTLTTFIFGIIERSLIPFGL
HHIFYSPFWFEFGSYTNHAGELVRGDQRIWMAQLRDGVPFTAGAFTTGKYPFMMFGLPAAAFAIYKNARPERKKVVGGLM
LSAGLTAFLTGITEPLEFSFLFVAPVLYGIHVLLAGTSFLVMHLLGVKIGMTFSGGFIDYILYGLLNWDRSHALLVIPVG
IVYAIVYYFLFDFAIRKFKLKTPGREDEETEIRNSSVAKLPFDVLDAMGGKENIKHLDACITRLRVEVVDKSKVDVAGIK
ALGASGVLEVGNNMQAIFGPKSDQIKHDMAKIMSGEITKPSETTVTEEMSDEPVHVEALGTTDIYAPGVGQIIPLSEVPD
QVFAGKMMGDGVGFIPEKGEIVAPFDGTVKTIFPTKHAIGLESGSGVEVLIHIGIDTVKLNGEGFESLINVDEKVTQGQP
LMKVNLAYLKAHAPSIVTPMIITNLENKELVIEDVQDADPGKLIMTVK

Sequences:

>Translated_688_residues
MFKKLFGQLQRIGKALMLPVAILPAAGILLAFGNAMHNEQLVEIAPWLKNDIIVMISSVMEASGQVVFDNLPLLFAVGTA
LGLAGGDGVAALAALVGYLIMNATMGKVLHITIDDIFSYAKGAKELSQAAKEPAHALVLGIPTLQTGVFGGIIMGALAAW
CYNKFYNITLPPFLGFFAGKRFVPIVTSVVAIATGVVLSFAWPPIQDGLNSLSNFLLNKNLTLTTFIFGIIERSLIPFGL
HHIFYSPFWFEFGSYTNHAGELVRGDQRIWMAQLRDGVPFTAGAFTTGKYPFMMFGLPAAAFAIYKNARPERKKVVGGLM
LSAGLTAFLTGITEPLEFSFLFVAPVLYGIHVLLAGTSFLVMHLLGVKIGMTFSGGFIDYILYGLLNWDRSHALLVIPVG
IVYAIVYYFLFDFAIRKFKLKTPGREDEETEIRNSSVAKLPFDVLDAMGGKENIKHLDACITRLRVEVVDKSKVDVAGIK
ALGASGVLEVGNNMQAIFGPKSDQIKHDMAKIMSGEITKPSETTVTEEMSDEPVHVEALGTTDIYAPGVGQIIPLSEVPD
QVFAGKMMGDGVGFIPEKGEIVAPFDGTVKTIFPTKHAIGLESGSGVEVLIHIGIDTVKLNGEGFESLINVDEKVTQGQP
LMKVNLAYLKAHAPSIVTPMIITNLENKELVIEDVQDADPGKLIMTVK
>Mature_688_residues
MFKKLFGQLQRIGKALMLPVAILPAAGILLAFGNAMHNEQLVEIAPWLKNDIIVMISSVMEASGQVVFDNLPLLFAVGTA
LGLAGGDGVAALAALVGYLIMNATMGKVLHITIDDIFSYAKGAKELSQAAKEPAHALVLGIPTLQTGVFGGIIMGALAAW
CYNKFYNITLPPFLGFFAGKRFVPIVTSVVAIATGVVLSFAWPPIQDGLNSLSNFLLNKNLTLTTFIFGIIERSLIPFGL
HHIFYSPFWFEFGSYTNHAGELVRGDQRIWMAQLRDGVPFTAGAFTTGKYPFMMFGLPAAAFAIYKNARPERKKVVGGLM
LSAGLTAFLTGITEPLEFSFLFVAPVLYGIHVLLAGTSFLVMHLLGVKIGMTFSGGFIDYILYGLLNWDRSHALLVIPVG
IVYAIVYYFLFDFAIRKFKLKTPGREDEETEIRNSSVAKLPFDVLDAMGGKENIKHLDACITRLRVEVVDKSKVDVAGIK
ALGASGVLEVGNNMQAIFGPKSDQIKHDMAKIMSGEITKPSETTVTEEMSDEPVHVEALGTTDIYAPGVGQIIPLSEVPD
QVFAGKMMGDGVGFIPEKGEIVAPFDGTVKTIFPTKHAIGLESGSGVEVLIHIGIDTVKLNGEGFESLINVDEKVTQGQP
LMKVNLAYLKAHAPSIVTPMIITNLENKELVIEDVQDADPGKLIMTVK

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787343, Length=513, Percent_Identity=49.317738791423, Blast_Score=444, Evalue=1e-125,
Organism=Escherichia coli, GI1786894, Length=678, Percent_Identity=38.0530973451327, Blast_Score=406, Evalue=1e-114,
Organism=Escherichia coli, GI1787908, Length=521, Percent_Identity=38.1957773512476, Blast_Score=321, Evalue=1e-88,
Organism=Escherichia coli, GI1788757, Length=133, Percent_Identity=44.3609022556391, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1790159, Length=124, Percent_Identity=40.3225806451613, Blast_Score=108, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR018113
- InterPro:   IPR001127
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011299 [H]

Pfam domain/function: PF00358 PTS_EIIA_1; PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 74361; Mature: 74361

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00371 PTS_EIIA_TYPE_1_HIS ; PS51093 PTS_EIIA_TYPE_1 ; PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKKLFGQLQRIGKALMLPVAILPAAGILLAFGNAMHNEQLVEIAPWLKNDIIVMISSVM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHH
EASGQVVFDNLPLLFAVGTALGLAGGDGVAALAALVGYLIMNATMGKVLHITIDDIFSYA
HCCCCEEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHH
KGAKELSQAAKEPAHALVLGIPTLQTGVFGGIIMGALAAWCYNKFYNITLPPFLGFFAGK
HHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCC
RFVPIVTSVVAIATGVVLSFAWPPIQDGLNSLSNFLLNKNLTLTTFIFGIIERSLIPFGL
CHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
HHIFYSPFWFEFGSYTNHAGELVRGDQRIWMAQLRDGVPFTAGAFTTGKYPFMMFGLPAA
HHHHHCCHHHHCCCCCCCCHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEECHHHH
AFAIYKNARPERKKVVGGLMLSAGLTAFLTGITEPLEFSFLFVAPVLYGIHVLLAGTSFL
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VMHLLGVKIGMTFSGGFIDYILYGLLNWDRSHALLVIPVGIVYAIVYYFLFDFAIRKFKL
HHHHHHHHCCEEECCHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHEEE
KTPGREDEETEIRNSSVAKLPFDVLDAMGGKENIKHLDACITRLRVEVVDKSKVDVAGIK
CCCCCCCCHHHHCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
ALGASGVLEVGNNMQAIFGPKSDQIKHDMAKIMSGEITKPSETTVTEEMSDEPVHVEALG
HCCCCCHHHCCCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCEEEEEEC
TTDIYAPGVGQIIPLSEVPDQVFAGKMMGDGVGFIPEKGEIVAPFDGTVKTIFPTKHAIG
CCCCCCCCCCCEEEHHHCCHHHHHCHHHCCCCCCCCCCCCEECCCCCCEEEECCCCCEEC
LESGSGVEVLIHIGIDTVKLNGEGFESLINVDEKVTQGQPLMKVNLAYLKAHAPSIVTPM
CCCCCCCEEEEEECCEEEEECCCCHHHHHCCHHHHCCCCCEEEEEHHHHHHCCCCCCCCH
IITNLENKELVIEDVQDADPGKLIMTVK
HHCCCCCCCEEEEECCCCCCCCEEEEEC
>Mature Secondary Structure
MFKKLFGQLQRIGKALMLPVAILPAAGILLAFGNAMHNEQLVEIAPWLKNDIIVMISSVM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHH
EASGQVVFDNLPLLFAVGTALGLAGGDGVAALAALVGYLIMNATMGKVLHITIDDIFSYA
HCCCCEEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHH
KGAKELSQAAKEPAHALVLGIPTLQTGVFGGIIMGALAAWCYNKFYNITLPPFLGFFAGK
HHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCC
RFVPIVTSVVAIATGVVLSFAWPPIQDGLNSLSNFLLNKNLTLTTFIFGIIERSLIPFGL
CHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
HHIFYSPFWFEFGSYTNHAGELVRGDQRIWMAQLRDGVPFTAGAFTTGKYPFMMFGLPAA
HHHHHCCHHHHCCCCCCCCHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEECHHHH
AFAIYKNARPERKKVVGGLMLSAGLTAFLTGITEPLEFSFLFVAPVLYGIHVLLAGTSFL
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VMHLLGVKIGMTFSGGFIDYILYGLLNWDRSHALLVIPVGIVYAIVYYFLFDFAIRKFKL
HHHHHHHHCCEEECCHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHEEE
KTPGREDEETEIRNSSVAKLPFDVLDAMGGKENIKHLDACITRLRVEVVDKSKVDVAGIK
CCCCCCCCHHHHCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
ALGASGVLEVGNNMQAIFGPKSDQIKHDMAKIMSGEITKPSETTVTEEMSDEPVHVEALG
HCCCCCHHHCCCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCEEEEEEC
TTDIYAPGVGQIIPLSEVPDQVFAGKMMGDGVGFIPEKGEIVAPFDGTVKTIFPTKHAIG
CCCCCCCCCCCEEEHHHCCHHHHHCHHHCCCCCCCCCCCCEECCCCCCEEEECCCCCEEC
LESGSGVEVLIHIGIDTVKLNGEGFESLINVDEKVTQGQPLMKVNLAYLKAHAPSIVTPM
CCCCCCCEEEEEECCEEEEECCCCHHHHHCCHHHHCCCCCEEEEEHHHHHHCCCCCCCCH
IITNLENKELVIEDVQDADPGKLIMTVK
HHCCCCCCCEEEEECCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA