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The map label for this gene is nreC [H]

Identifier: 82751986

GI number: 82751986

Start: 2400344

End: 2400997

Strand: Reverse

Name: nreC [H]

Synonym: SAB2270c

Alternate gene names: 82751986

Gene position: 2400997-2400344 (Counterclockwise)

Preceding gene: 82751987

Following gene: 82751983

Centisome position: 87.55

GC content: 33.79

Gene sequence:

>654_bases
TTGAAAATAGTTATTGCCGATGATCACGCTGTTGTCCGTACGGGGTTCTCTATGATTTTAAATTATCAAAATGATATGGA
AGTTGTTGCAACGGCTGCAGATGGCGTCGAAGCTTACCAAAAAGTAATGGAATATAAACCTGATGTGTTACTAATGGATT
TAAGTATGCCACCAGGTGAGTCAGGTCTTATCGCTACGAGTAAAATTGCTGACAGTTTTCCTGAAACTAAAATACTAATA
TTAACAATGTTTGATGATGAGGAGTATTTGTTCCATGTGTTGCGTAATGGTGCGAAAGGTTACATATTGAAAAATGCACC
TGATGAACAATTATTGTTAGCTATTCGAACTGTATATAAAGGTGAAACATATGTAGATATGAAACTTACAACATCTTTAG
TGAATGAATTTGTATCTAATTCAAATCAGGACACTGCAAACACATCAGATCCTTTTAAAATCTTATCAAAACGAGAACTA
GAAATATTGCCACTTATTGCCAAAGGTTACGGGAATAAAGAAATTGCAGAGAAATTATTTGTATCTGTGAAAACAGTAGA
AGCACATAAGACGCATATTATGACAAAGCTTGGCTTAAAGAGTAAACCTGAGCTAGTTGAATATGCATTGAAAAAGAAAT
TATTAGAGTTTTAG

Upstream 100 bases:

>100_bases
GAGTTAGTCAGCGGTAGCGTCAATATTGAAACGAAAATTGGTGAGGGGACCAATGTTACATTGAACATTCCAATTTGAAA
CATACATTGGGGGAATAAAA

Downstream 100 bases:

>100_bases
AGCTTGAAATTAATATAATTCAGTATAAAAGCGCGAGAGGAAATGATTATCTTCTGGCGCTTTTGTATGTTTCGAAATAT
ATTTTTTTATAAATCGAATG

Product: two-component response regulator

Products: NA

Alternate protein names: Nitrogen regulation protein C [H]

Number of amino acids: Translated: 217; Mature: 217

Protein sequence:

>217_residues
MKIVIADDHAVVRTGFSMILNYQNDMEVVATAADGVEAYQKVMEYKPDVLLMDLSMPPGESGLIATSKIADSFPETKILI
LTMFDDEEYLFHVLRNGAKGYILKNAPDEQLLLAIRTVYKGETYVDMKLTTSLVNEFVSNSNQDTANTSDPFKILSKREL
EILPLIAKGYGNKEIAEKLFVSVKTVEAHKTHIMTKLGLKSKPELVEYALKKKLLEF

Sequences:

>Translated_217_residues
MKIVIADDHAVVRTGFSMILNYQNDMEVVATAADGVEAYQKVMEYKPDVLLMDLSMPPGESGLIATSKIADSFPETKILI
LTMFDDEEYLFHVLRNGAKGYILKNAPDEQLLLAIRTVYKGETYVDMKLTTSLVNEFVSNSNQDTANTSDPFKILSKREL
EILPLIAKGYGNKEIAEKLFVSVKTVEAHKTHIMTKLGLKSKPELVEYALKKKLLEF
>Mature_217_residues
MKIVIADDHAVVRTGFSMILNYQNDMEVVATAADGVEAYQKVMEYKPDVLLMDLSMPPGESGLIATSKIADSFPETKILI
LTMFDDEEYLFHVLRNGAKGYILKNAPDEQLLLAIRTVYKGETYVDMKLTTSLVNEFVSNSNQDTANTSDPFKILSKREL
EILPLIAKGYGNKEIAEKLFVSVKTVEAHKTHIMTKLGLKSKPELVEYALKKKLLEF

Specific function: Member of the two-component regulatory system nreB/nreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. Phosphorylated nreC binds to a GC-rich palindromic sequence at the promoters of the nitrate (narGHJI) and nit

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=215, Percent_Identity=35.3488372093023, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1788521, Length=201, Percent_Identity=35.3233830845771, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1786747, Length=211, Percent_Identity=29.8578199052133, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1790102, Length=207, Percent_Identity=30.9178743961353, Blast_Score=95, Evalue=3e-21,
Organism=Escherichia coli, GI1788712, Length=216, Percent_Identity=31.0185185185185, Blast_Score=94, Evalue=5e-21,
Organism=Escherichia coli, GI1787473, Length=187, Percent_Identity=33.1550802139037, Blast_Score=84, Evalue=6e-18,
Organism=Escherichia coli, GI1788546, Length=210, Percent_Identity=30, Blast_Score=77, Evalue=6e-16,
Organism=Escherichia coli, GI1789937, Length=204, Percent_Identity=25.4901960784314, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 24355; Mature: 24355

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIVIADDHAVVRTGFSMILNYQNDMEVVATAADGVEAYQKVMEYKPDVLLMDLSMPPGE
CEEEEECCCHHHHHHHHHEEECCCCCEEEEEHHHHHHHHHHHHHCCCCEEEEEECCCCCC
SGLIATSKIADSFPETKILILTMFDDEEYLFHVLRNGAKGYILKNAPDEQLLLAIRTVYK
CCCEEEHHHHCCCCCCEEEEEEEECCHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHC
GETYVDMKLTTSLVNEFVSNSNQDTANTSDPFKILSKRELEILPLIAKGYGNKEIAEKLF
CCEEEEHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCEEEEEEECCCCCHHHHHHHH
VSVKTVEAHKTHIMTKLGLKSKPELVEYALKKKLLEF
HHHHEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKIVIADDHAVVRTGFSMILNYQNDMEVVATAADGVEAYQKVMEYKPDVLLMDLSMPPGE
CEEEEECCCHHHHHHHHHEEECCCCCEEEEEHHHHHHHHHHHHHCCCCEEEEEECCCCCC
SGLIATSKIADSFPETKILILTMFDDEEYLFHVLRNGAKGYILKNAPDEQLLLAIRTVYK
CCCEEEHHHHCCCCCCEEEEEEEECCHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHC
GETYVDMKLTTSLVNEFVSNSNQDTANTSDPFKILSKRELEILPLIAKGYGNKEIAEKLF
CCEEEEHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCEEEEEEECCCCCHHHHHHHH
VSVKTVEAHKTHIMTKLGLKSKPELVEYALKKKLLEF
HHHHEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA