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The map label for this gene is moaC

Identifier: 82751862

GI number: 82751862

Start: 2280648

End: 2281142

Strand: Direct

Name: moaC

Synonym: SAB2146

Alternate gene names: 82751862

Gene position: 2280648-2281142 (Clockwise)

Preceding gene: 82751854

Following gene: 82751868

Centisome position: 83.16

GC content: 38.59

Gene sequence:

>495_bases
ATGACTGAGTTTACTCATATTAATCAACAAGGCCACGCCAAAATGGTCGATGTATCAGACAAACAAATTACAAAAAGAAC
TGCTGTTGCTCATTCAAGCATTACTGTGAATGAAACTATTTATAAGCAGATTTCTAATAACACCAATACCAAAGGCAATG
TATTGAACACTGCTCAAATCGCTGGTATTATGGCTGCCAAAAATACATCAACAATTATTCCGATGTGCCATCCATTACCA
TTGACTGGCATAGATGTTCACTTCAGCTGGGATGAAACAAATGCACCCCTTTATACTTTAAACATTCAAACAACTGTCTC
TACAACTGGCAAAACCGGTGTTGAAATGGAAGCTTTAACCGCTGCATCAGCAACGGCTTTAACCATTTACGACATGACGA
AAGCAGTTGATAAAGGTATGATTATTGGCGAAACCTACCTTGAAAGCAAGTCTGGCGGTAAATCTGGAGATTTTCAACGC
CAATCAGGTCAATAA

Upstream 100 bases:

>100_bases
TCTTTAACTGGGATTGGGTTTCTTTTTTCTACTACCATTAAAAATCATCTCCAAAACTTTTATTTTTTCATGATATACTA
GATGCACTAGGAGGGGTAAA

Downstream 100 bases:

>100_bases
ATTATTTTGTAAGCTCATGAATCAGATGATTTAATTCTGGTTTAATGAGCTTTTCTAATGCTAATTTAACTGCGCCTGTT
GATCCTGGAATCGAAAATAT

Product: molybdenum cofactor biosynthesis protein MoaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 164; Mature: 163

Protein sequence:

>164_residues
MTEFTHINQQGHAKMVDVSDKQITKRTAVAHSSITVNETIYKQISNNTNTKGNVLNTAQIAGIMAAKNTSTIIPMCHPLP
LTGIDVHFSWDETNAPLYTLNIQTTVSTTGKTGVEMEALTAASATALTIYDMTKAVDKGMIIGETYLESKSGGKSGDFQR
QSGQ

Sequences:

>Translated_164_residues
MTEFTHINQQGHAKMVDVSDKQITKRTAVAHSSITVNETIYKQISNNTNTKGNVLNTAQIAGIMAAKNTSTIIPMCHPLP
LTGIDVHFSWDETNAPLYTLNIQTTVSTTGKTGVEMEALTAASATALTIYDMTKAVDKGMIIGETYLESKSGGKSGDFQR
QSGQ
>Mature_163_residues
TEFTHINQQGHAKMVDVSDKQITKRTAVAHSSITVNETIYKQISNNTNTKGNVLNTAQIAGIMAAKNTSTIIPMCHPLPL
TGIDVHFSWDETNAPLYTLNIQTTVSTTGKTGVEMEALTAASATALTIYDMTKAVDKGMIIGETYLESKSGGKSGDFQRQ
SGQ

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family [H]

Homologues:

Organism=Escherichia coli, GI1787001, Length=163, Percent_Identity=50.920245398773, Blast_Score=152, Evalue=8e-39,
Organism=Caenorhabditis elegans, GI32566331, Length=152, Percent_Identity=46.0526315789474, Blast_Score=138, Evalue=1e-33,
Organism=Drosophila melanogaster, GI28574490, Length=163, Percent_Identity=46.0122699386503, Blast_Score=138, Evalue=2e-33,
Organism=Drosophila melanogaster, GI28574492, Length=150, Percent_Identity=46.6666666666667, Blast_Score=130, Evalue=6e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820 [H]

Pfam domain/function: PF01967 MoaC [H]

EC number: NA

Molecular weight: Translated: 17653; Mature: 17522

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEFTHINQQGHAKMVDVSDKQITKRTAVAHSSITVNETIYKQISNNTNTKGNVLNTAQI
CCCCCCCCCCCCEEEEECCCHHHHHHHHHCCCCEEEHHHHHHHHCCCCCCCCCEEEHHHH
AGIMAAKNTSTIIPMCHPLPLTGIDVHFSWDETNAPLYTLNIQTTVSTTGKTGVEMEALT
EEEEEECCCCEEEEECCCCCCCCEEEEEECCCCCCCEEEEEEEEEEECCCCCCCEEEEEE
AASATALTIYDMTKAVDKGMIIGETYLESKSGGKSGDFQRQSGQ
CCCCEEEEEEHHHHHHHCCEEEEHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TEFTHINQQGHAKMVDVSDKQITKRTAVAHSSITVNETIYKQISNNTNTKGNVLNTAQI
CCCCCCCCCCCEEEEECCCHHHHHHHHHCCCCEEEHHHHHHHHCCCCCCCCCEEEHHHH
AGIMAAKNTSTIIPMCHPLPLTGIDVHFSWDETNAPLYTLNIQTTVSTTGKTGVEMEALT
EEEEEECCCCEEEEECCCCCCCCEEEEEECCCCCCCEEEEEEEEEEECCCCCCCEEEEEE
AASATALTIYDMTKAVDKGMIIGETYLESKSGGKSGDFQRQSGQ
CCCCEEEEEEHHHHHHHCCEEEEHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA