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The map label for this gene is moaE

Identifier: 82751859

GI number: 82751859

Start: 2278384

End: 2278830

Strand: Reverse

Name: moaE

Synonym: SAB2143c

Alternate gene names: 82751859

Gene position: 2278830-2278384 (Counterclockwise)

Preceding gene: 82751860

Following gene: 82751858

Centisome position: 83.09

GC content: 35.57

Gene sequence:

>447_bases
ATGAAACAATTTGAAATCGTGACAGAACCGATACAAACAGAACAATATCGTGAATTCACTATAAATGAATATCAAGGTGC
AGTAGTTGTTTTTACCGGTCATGTTCGCGAATGGACTAAAGGCGTCAAAACGGAATATTTAGAATATGAAGCGTATATTC
CAATGGCTGAAAAGAAATTGGCACAAATTGGAGATGAAATAAATGAAAAATGGCCTGGAACGATAACGAGTATTGTTCAT
AGAATAGGGCTATTACAAATTTCAGATATCGCTGTATTAATTGCAGTTTCTTCACCGCATCGTAAAGATGCCTATCGAGC
AAATGAATATGCAATTGAGCGTATAAAAGAAATTGTTCCGATTTGGAAAAAAGAAATTTGGGAAGATGGTTCAAAATGGC
AAGGGCATCAAAAAGGGAATTATGAAGAAGCGAAGAGGGAGGAATAA

Upstream 100 bases:

>100_bases
AATGTTAGGGAGCATGAAGACTTTACAGCATTTGAGCAATGGTTATTAAATAAAATTAAAAATGATTGTGATACACAATT
AACATAGAGGATTGAAATGA

Downstream 100 bases:

>100_bases
GAGAAATGAAGGTACTTTACTTCGCAGAAATTAAAGATATATTACAAAAAGCACAGGAAGATATTATGTTTGAACAAGCA
TTGACTGTACAACAATTTGA

Product: molybdopterin converting factor small subunit

Products: NA

Alternate protein names: MPT synthase subunit 2; Molybdenum cofactor biosynthesis protein E; Molybdopterin-converting factor large subunit; Molybdopterin-converting factor subunit 2 [H]

Number of amino acids: Translated: 148; Mature: 148

Protein sequence:

>148_residues
MKQFEIVTEPIQTEQYREFTINEYQGAVVVFTGHVREWTKGVKTEYLEYEAYIPMAEKKLAQIGDEINEKWPGTITSIVH
RIGLLQISDIAVLIAVSSPHRKDAYRANEYAIERIKEIVPIWKKEIWEDGSKWQGHQKGNYEEAKREE

Sequences:

>Translated_148_residues
MKQFEIVTEPIQTEQYREFTINEYQGAVVVFTGHVREWTKGVKTEYLEYEAYIPMAEKKLAQIGDEINEKWPGTITSIVH
RIGLLQISDIAVLIAVSSPHRKDAYRANEYAIERIKEIVPIWKKEIWEDGSKWQGHQKGNYEEAKREE
>Mature_148_residues
MKQFEIVTEPIQTEQYREFTINEYQGAVVVFTGHVREWTKGVKTEYLEYEAYIPMAEKKLAQIGDEINEKWPGTITSIVH
RIGLLQISDIAVLIAVSSPHRKDAYRANEYAIERIKEIVPIWKKEIWEDGSKWQGHQKGNYEEAKREE

Specific function: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by moaD [H]

COG id: COG0314

COG function: function code H; Molybdopterin converting factor, large subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaE family [H]

Homologues:

Organism=Homo sapiens, GI4758732, Length=129, Percent_Identity=41.0852713178295, Blast_Score=115, Evalue=1e-26,
Organism=Escherichia coli, GI1787003, Length=133, Percent_Identity=36.0902255639098, Blast_Score=90, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17509279, Length=122, Percent_Identity=37.7049180327869, Blast_Score=77, Evalue=5e-15,
Organism=Drosophila melanogaster, GI21356259, Length=137, Percent_Identity=35.7664233576642, Blast_Score=95, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003448 [H]

Pfam domain/function: PF02391 MoaE [H]

EC number: NA

Molecular weight: Translated: 17355; Mature: 17355

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQFEIVTEPIQTEQYREFTINEYQGAVVVFTGHVREWTKGVKTEYLEYEAYIPMAEKKL
CCCCCHHCCCCCCHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCHHHHHH
AQIGDEINEKWPGTITSIVHRIGLLQISDIAVLIAVSSPHRKDAYRANEYAIERIKEIVP
HHHHHHHHCCCCCHHHHHHHHHCCCEECCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHH
IWKKEIWEDGSKWQGHQKGNYEEAKREE
HHHHHHHCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKQFEIVTEPIQTEQYREFTINEYQGAVVVFTGHVREWTKGVKTEYLEYEAYIPMAEKKL
CCCCCHHCCCCCCHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCHHHHHH
AQIGDEINEKWPGTITSIVHRIGLLQISDIAVLIAVSSPHRKDAYRANEYAIERIKEIVP
HHHHHHHHCCCCCHHHHHHHHHCCCEECCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHH
IWKKEIWEDGSKWQGHQKGNYEEAKREE
HHHHHHHCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA