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The map label for this gene is pbuG [H]

Identifier: 82751842

GI number: 82751842

Start: 2259549

End: 2260883

Strand: Reverse

Name: pbuG [H]

Synonym: SAB2125c

Alternate gene names: 82751842

Gene position: 2260883-2259549 (Counterclockwise)

Preceding gene: 82751845

Following gene: 82751840

Centisome position: 82.44

GC content: 35.36

Gene sequence:

>1335_bases
GTGAAAAACTATTTCCAGTTCGATAAATATGGAACAAACTTTAAAAGAGAAATCTTAGGCGGTATCACAACTTTCTTATC
TATGGCCTATATTTTAGCAGTTAACCCGCAAGTTTTAAGTTTAGCAGGTGTTAAAGGTGTATCAGATGATATGAAAATGG
ACCAAGGTGCCATTTTTGTAGCGACTGCATTAGCAGCATTTGTAGGCTCGCTATTCATGGGGCTAATAGCTAAATATCCA
ATTGCGTTAGCACCAGGTATGGGATTAAATGCATTCTTTGCATTTACTGTTGTGTTAACCATGGGTATTCCTTGGCAAGT
TGGTTTAACAGGTGTTTTATTCTCAGGTATATTCTTTGCGATATTAACCGTCACAGGGTTTAGGGAAGTTATTATTAATG
CAATTCCTTATCAAATGAAGATGGCTGTTTCAGCAGGTATAGGGTTATTCATTACATTTGTAGGTTTACAAAGTTCGGGT
ATTATAGTTAAAAATGAATCTACATTAGTAACATTGGGACATTTAACTGATCCACCAGTACTTTTAGCGATATTCGGTAT
CGTTATTACAGTTATTTTATATGCAATTAAATTGCCGGGTTCTATCTTTATCGGTATGATCATCACAGCAATCGTTGGTA
TGTTCACTGGATTGATTCAAATGCCATCTGGTATTGTAGGTAAGATTCCAAGTATTGAACCAACGTTCGGTGCTGTATTT
GAAGCGTTTAAAGACCCAAGTCAATTATTAACGATACAGTTCTTAATTGTTATTTTAACGTTCTTATTTATTGATTTCTT
TGATACAGCTGGTACATTAGTAGCCGTTGCTACTCAAGCAGGTATTATGAAAGATAATAAATTACCAAGAGCTGGTAGAG
CATTGTTCTCAGATTCTTTAGCTACGATTGTAGGGTCAGTTTTTGGAACAACTACAACAACTTCTTATATCGAATCAACT
TCAGGTGTTGCTGTAGGTGCTAGAACAGGATTTGCTAGTATCGTAACAGGTTGTTGTTTCCTATTAGCGCTATTCTTTAG
TCCGTTAATCGCTGTTGTAACAAGTGCAGTTACGACACCAGCTTTAGTGGTGGTAGGTGTATTAATGGCTGCAAACTTTG
CTGAGATAAACTGGAAAAGTTTTGAAGTTGCAGTGCCAGCATTCATTACAATCATTATGATGCCTTTATCATATTCAATT
GCAACTGGTATTGCGTGTGGATTTATTTTCTATCCAATTACAATGCTTATCTCTAAAAAACATAAAGAAGTACATCCGAT
AATGTATGTATTAATGGTACTATTCATTCTGTACTTCATATTTGTTCATGGTTAA

Upstream 100 bases:

>100_bases
AAAGTTGAATCAGAAAAATGAAAAGTTCGCTTTTGGTATTGTTTTTTATTAAGAATGATATTAAACTATTAAGGTATTTT
AAAAAAAGGAGCATCCATTC

Downstream 100 bases:

>100_bases
ATCCAGACACAAAAAACGACTGCCAATGATTGGTAGTCGTTTTTTTCTTTGAAGTAAGGATAAAATAAGAAGCGAAATAG
CATAAAGCAATATTATGAAT

Product: permease family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:

>444_residues
MKNYFQFDKYGTNFKREILGGITTFLSMAYILAVNPQVLSLAGVKGVSDDMKMDQGAIFVATALAAFVGSLFMGLIAKYP
IALAPGMGLNAFFAFTVVLTMGIPWQVGLTGVLFSGIFFAILTVTGFREVIINAIPYQMKMAVSAGIGLFITFVGLQSSG
IIVKNESTLVTLGHLTDPPVLLAIFGIVITVILYAIKLPGSIFIGMIITAIVGMFTGLIQMPSGIVGKIPSIEPTFGAVF
EAFKDPSQLLTIQFLIVILTFLFIDFFDTAGTLVAVATQAGIMKDNKLPRAGRALFSDSLATIVGSVFGTTTTTSYIEST
SGVAVGARTGFASIVTGCCFLLALFFSPLIAVVTSAVTTPALVVVGVLMAANFAEINWKSFEVAVPAFITIIMMPLSYSI
ATGIACGFIFYPITMLISKKHKEVHPIMYVLMVLFILYFIFVHG

Sequences:

>Translated_444_residues
MKNYFQFDKYGTNFKREILGGITTFLSMAYILAVNPQVLSLAGVKGVSDDMKMDQGAIFVATALAAFVGSLFMGLIAKYP
IALAPGMGLNAFFAFTVVLTMGIPWQVGLTGVLFSGIFFAILTVTGFREVIINAIPYQMKMAVSAGIGLFITFVGLQSSG
IIVKNESTLVTLGHLTDPPVLLAIFGIVITVILYAIKLPGSIFIGMIITAIVGMFTGLIQMPSGIVGKIPSIEPTFGAVF
EAFKDPSQLLTIQFLIVILTFLFIDFFDTAGTLVAVATQAGIMKDNKLPRAGRALFSDSLATIVGSVFGTTTTTSYIEST
SGVAVGARTGFASIVTGCCFLLALFFSPLIAVVTSAVTTPALVVVGVLMAANFAEINWKSFEVAVPAFITIIMMPLSYSI
ATGIACGFIFYPITMLISKKHKEVHPIMYVLMVLFILYFIFVHG
>Mature_444_residues
MKNYFQFDKYGTNFKREILGGITTFLSMAYILAVNPQVLSLAGVKGVSDDMKMDQGAIFVATALAAFVGSLFMGLIAKYP
IALAPGMGLNAFFAFTVVLTMGIPWQVGLTGVLFSGIFFAILTVTGFREVIINAIPYQMKMAVSAGIGLFITFVGLQSSG
IIVKNESTLVTLGHLTDPPVLLAIFGIVITVILYAIKLPGSIFIGMIITAIVGMFTGLIQMPSGIVGKIPSIEPTFGAVF
EAFKDPSQLLTIQFLIVILTFLFIDFFDTAGTLVAVATQAGIMKDNKLPRAGRALFSDSLATIVGSVFGTTTTTSYIEST
SGVAVGARTGFASIVTGCCFLLALFFSPLIAVVTSAVTTPALVVVGVLMAANFAEINWKSFEVAVPAFITIIMMPLSYSI
ATGIACGFIFYPITMLISKKHKEVHPIMYVLMVLFILYFIFVHG

Specific function: Involved in the uptake of the purine bases hypoxanthine and guanine [H]

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082309, Length=444, Percent_Identity=40.5405405405405, Blast_Score=332, Evalue=3e-92,
Organism=Escherichia coli, GI1790150, Length=443, Percent_Identity=40.6320541760722, Blast_Score=322, Evalue=3e-89,
Organism=Escherichia coli, GI1790499, Length=449, Percent_Identity=32.0712694877506, Blast_Score=211, Evalue=9e-56,
Organism=Escherichia coli, GI48994909, Length=435, Percent_Identity=33.3333333333333, Blast_Score=201, Evalue=7e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 47411; Mature: 47411

Theoretical pI: Translated: 8.72; Mature: 8.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969499; 9384377; 11591660 [H]