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The map label for this gene is mtlR [H]

Identifier: 82751754

GI number: 82751754

Start: 2170064

End: 2172196

Strand: Direct

Name: mtlR [H]

Synonym: SAB2037

Alternate gene names: 82751754

Gene position: 2170064-2172196 (Clockwise)

Preceding gene: 82751753

Following gene: 82751755

Centisome position: 79.13

GC content: 33.1

Gene sequence:

>2133_bases
ATGTTATTGAGTACACGTGAAAAAGAAATGATAGCCCTATTGATTAAGTACCACGGTCAATATATCACTATACACGACAT
TGCTCAGCAACTTGCGGTGTCCTCTCGTACTATTCACCGTGAATTAAAAGGTGTTGAAGCATATTTAACTTCATTTTCAT
TAACTTTAGAACGCGCAAACAAAAAAGGGCTACGTATTGCTGGCGAAAATTCTGATTTAAACGATTTGAAGCAATCGATC
GCACAACATCAAACCATTGACTTATCTGTTGAAGAGCAGAAAGTAATTATTATATACGCTTTGATACAAGCCAAGGAGCC
AGTTAAACAATATAGTTTAGCGCAAGAAATTGGCGTTTCTGTCCAGACTTTAGCAAAGATGTTAGATGATTTAGAGCTCT
ATTTAAATAAGTACCAACTATCTTTATCTCGAAAGCGTGGCGAAGGTATTTACTTGGTAGGTACCGAATCGAAGAAACGT
GAATTTTTAAGTCAATTAATGGTGAATAACTTAAATAGTACTAGCGTTTATTCAGTAATTGAAAATCATTTTGTCTTTCA
TTCATTAAATCAAATCCACAAAGACTTTGTTGACTTAGAGCGTATTTTTAATGTTGAAAGACTATTAATGGACTACCTAA
GTGCCTTACCCTACCAACTTACCGAATCAAGTTATTTAACTTTAACTGTCCATATCGTGCTATCAATTTCACGTATAAAA
AATGGAGAGTATGTCGCATTAAACGATGATATTTATGATTCTGTACAAAACACATTTGAACACAAAGTAGCAAGCGAACT
TGCTGATAAACTTGGTCAAATATATGACGTCACGTTTAATCAGGCAGAAATTGATTTCATTACTATCCATTTACGTGGTG
CTAAACGAAAAAATCTTAATGATACATCATTAAATAATCGTTGTGAAGAAAACAAAATTAAAGCGTTTGTTAAAAAAGTA
GAAATGATTTCAGGTATGACATTTGCAGATTTGGATACTTTAGTAGATGGACTGACGCTACACCTTAATCCTGCAATCAA
TCGTTTGCAAGCTAATATCGAGACCTATAATCCGTTAACAGACATGATTAAGTTCAAATATCCAAGACTGTTTGAAAATG
TAAGATTAGCTTTAAATGATTGTTGGCCTGATTTGATTTTTCCAGAAAGTGAAATTGCTTTTATAGTTTTACACTTTGGT
GGCTCGATTAAAAACCAAGGTAATCGATTTTTAAACATATTAGTCGTTTGCAGCAGTGGTATGGGAACTAGCCGTCTATT
ATCAACTCGTCTAGAGCAAGTTTTTAGTGAGATTGAGCGTATTACACAAGCATCAGTCAGCGATTTGAAGTCACTAGATT
TAAGTCAATATGATGGCATTATTTCTACTGTGAATTTAGACATCGACTCCCCCTATTTAACGGTAAACCCATTATTACCA
GATAGTGATATCAGTTATGTCGCACAGTTTTTAAATACAAAGTCTACGTTCCAAGAGACGCATGATAAATCATCAAACAT
GATTGATAAAGATGATGTTCATGTTGAAACGAAAGATATTGATGGCAACACATCTTTTGAAAATGAACAAACTTCAAACT
TAACTTCAGTTTTCGAAAAACATTTAAGTGACGAAAAATCAGAACAATTAATGCATCATATGCGTTCGGGTTTAACTTTG
CTTGATTCAGTGAAAATAGTTAGTACCGAAGTTAAACAGTGGCAAACATATATCGCAGATTATCTATATCAATGCGATGC
AATAAAAGATCCAACGTCATTCGCTGAACTACTAGAGCAACGATTGATTGACAATCCAGGATGGATATTAAGTCCATATC
CTGTTGCAATACCACACCTAAGAGACAATATGATTAAACACCCTATGATTCTAATCACAGTTTTAGAAGAACCGTTAGCA
TTGCCTAGTATTCAAAATGACAATCAAACAATTAAATATATGATTTCCATGTTTATTCCTGACAATGATTTTATGGCATC
ACTGGTAAGTGACTTGTCCGAATTTTTAAGTTTGAAATTAGAATCTATTGATACTTTTATGAAAAATCCACAGGAACTTG
AAACATTATTAAGAAACAAATTTTTAGAACGAATTAAAAAACAATTTATTTAG

Upstream 100 bases:

>100_bases
AATTTCCTTAATTCACCAAGATATGAAGAACTTTTAAATAATCTAAAAAAAGATGATCAAGCATAATAATTAAATAAATT
AAAAAATGGAGGATACCGCC

Downstream 100 bases:

>100_bases
GAGTGTACAAAATGAGCGAATTATTTAGTAATGACAATATCTTTTTAAATGTAAATGTTAACAGCCAAAATGAAGCAATT
GAAAAAGCAGGTAAAGCCTT

Product: transcription antiterminator

Products: NA

Alternate protein names: Mannitol operon transcriptional activator; Mtl operon transcriptional activator; Putative phosphotransferase enzyme IIB component; Putative PTS system EIIB component; Putative phosphotransferase enzyme IIA component; Putative PTS system EIIA component [H]

Number of amino acids: Translated: 710; Mature: 710

Protein sequence:

>710_residues
MLLSTREKEMIALLIKYHGQYITIHDIAQQLAVSSRTIHRELKGVEAYLTSFSLTLERANKKGLRIAGENSDLNDLKQSI
AQHQTIDLSVEEQKVIIIYALIQAKEPVKQYSLAQEIGVSVQTLAKMLDDLELYLNKYQLSLSRKRGEGIYLVGTESKKR
EFLSQLMVNNLNSTSVYSVIENHFVFHSLNQIHKDFVDLERIFNVERLLMDYLSALPYQLTESSYLTLTVHIVLSISRIK
NGEYVALNDDIYDSVQNTFEHKVASELADKLGQIYDVTFNQAEIDFITIHLRGAKRKNLNDTSLNNRCEENKIKAFVKKV
EMISGMTFADLDTLVDGLTLHLNPAINRLQANIETYNPLTDMIKFKYPRLFENVRLALNDCWPDLIFPESEIAFIVLHFG
GSIKNQGNRFLNILVVCSSGMGTSRLLSTRLEQVFSEIERITQASVSDLKSLDLSQYDGIISTVNLDIDSPYLTVNPLLP
DSDISYVAQFLNTKSTFQETHDKSSNMIDKDDVHVETKDIDGNTSFENEQTSNLTSVFEKHLSDEKSEQLMHHMRSGLTL
LDSVKIVSTEVKQWQTYIADYLYQCDAIKDPTSFAELLEQRLIDNPGWILSPYPVAIPHLRDNMIKHPMILITVLEEPLA
LPSIQNDNQTIKYMISMFIPDNDFMASLVSDLSEFLSLKLESIDTFMKNPQELETLLRNKFLERIKKQFI

Sequences:

>Translated_710_residues
MLLSTREKEMIALLIKYHGQYITIHDIAQQLAVSSRTIHRELKGVEAYLTSFSLTLERANKKGLRIAGENSDLNDLKQSI
AQHQTIDLSVEEQKVIIIYALIQAKEPVKQYSLAQEIGVSVQTLAKMLDDLELYLNKYQLSLSRKRGEGIYLVGTESKKR
EFLSQLMVNNLNSTSVYSVIENHFVFHSLNQIHKDFVDLERIFNVERLLMDYLSALPYQLTESSYLTLTVHIVLSISRIK
NGEYVALNDDIYDSVQNTFEHKVASELADKLGQIYDVTFNQAEIDFITIHLRGAKRKNLNDTSLNNRCEENKIKAFVKKV
EMISGMTFADLDTLVDGLTLHLNPAINRLQANIETYNPLTDMIKFKYPRLFENVRLALNDCWPDLIFPESEIAFIVLHFG
GSIKNQGNRFLNILVVCSSGMGTSRLLSTRLEQVFSEIERITQASVSDLKSLDLSQYDGIISTVNLDIDSPYLTVNPLLP
DSDISYVAQFLNTKSTFQETHDKSSNMIDKDDVHVETKDIDGNTSFENEQTSNLTSVFEKHLSDEKSEQLMHHMRSGLTL
LDSVKIVSTEVKQWQTYIADYLYQCDAIKDPTSFAELLEQRLIDNPGWILSPYPVAIPHLRDNMIKHPMILITVLEEPLA
LPSIQNDNQTIKYMISMFIPDNDFMASLVSDLSEFLSLKLESIDTFMKNPQELETLLRNKFLERIKKQFI
>Mature_710_residues
MLLSTREKEMIALLIKYHGQYITIHDIAQQLAVSSRTIHRELKGVEAYLTSFSLTLERANKKGLRIAGENSDLNDLKQSI
AQHQTIDLSVEEQKVIIIYALIQAKEPVKQYSLAQEIGVSVQTLAKMLDDLELYLNKYQLSLSRKRGEGIYLVGTESKKR
EFLSQLMVNNLNSTSVYSVIENHFVFHSLNQIHKDFVDLERIFNVERLLMDYLSALPYQLTESSYLTLTVHIVLSISRIK
NGEYVALNDDIYDSVQNTFEHKVASELADKLGQIYDVTFNQAEIDFITIHLRGAKRKNLNDTSLNNRCEENKIKAFVKKV
EMISGMTFADLDTLVDGLTLHLNPAINRLQANIETYNPLTDMIKFKYPRLFENVRLALNDCWPDLIFPESEIAFIVLHFG
GSIKNQGNRFLNILVVCSSGMGTSRLLSTRLEQVFSEIERITQASVSDLKSLDLSQYDGIISTVNLDIDSPYLTVNPLLP
DSDISYVAQFLNTKSTFQETHDKSSNMIDKDDVHVETKDIDGNTSFENEQTSNLTSVFEKHLSDEKSEQLMHHMRSGLTL
LDSVKIVSTEVKQWQTYIADYLYQCDAIKDPTSFAELLEQRLIDNPGWILSPYPVAIPHLRDNMIKHPMILITVLEEPLA
LPSIQNDNQTIKYMISMFIPDNDFMASLVSDLSEFLSLKLESIDTFMKNPQELETLLRNKFLERIKKQFI

Specific function: Positively regulates the expression of the mtlAFD operon involved in the uptake and catabolism of mannitol [H]

COG id: COG3711

COG function: function code K; Transcriptional antiterminator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIB type-2 domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013196
- InterPro:   IPR007737
- InterPro:   IPR011608
- InterPro:   IPR016152
- InterPro:   IPR002178
- InterPro:   IPR013011
- InterPro:   IPR003501
- InterPro:   IPR011991 [H]

Pfam domain/function: PF08279 HTH_11; PF05043 Mga; PF00874 PRD; PF02302 PTS_IIB [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 81228; Mature: 81228

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS51094 PTS_EIIA_TYPE_2 ; PS51099 PTS_EIIB_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLSTREKEMIALLIKYHGQYITIHDIAQQLAVSSRTIHRELKGVEAYLTSFSLTLERAN
CCCCCCHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KKGLRIAGENSDLNDLKQSIAQHQTIDLSVEEQKVIIIYALIQAKEPVKQYSLAQEIGVS
CCCCEEECCCCCHHHHHHHHHHCCEEEEEECCCEEEEEEEEHHCCCHHHHHHHHHHHCCC
VQTLAKMLDDLELYLNKYQLSLSRKRGEGIYLVGTESKKREFLSQLMVNNLNSTSVYSVI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHCCCCCHHHHHHH
ENHFVFHSLNQIHKDFVDLERIFNVERLLMDYLSALPYQLTESSYLTLTVHIVLSISRIK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCEEEEEHHHHHHHHHCC
NGEYVALNDDIYDSVQNTFEHKVASELADKLGQIYDVTFNQAEIDFITIHLRGAKRKNLN
CCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCEEEEEEEEEEECCCCCCCC
DTSLNNRCEENKIKAFVKKVEMISGMTFADLDTLVDGLTLHLNPAINRLQANIETYNPLT
CCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCEEEEECHHHHHHHHCCHHCCCHH
DMIKFKYPRLFENVRLALNDCWPDLIFPESEIAFIVLHFGGSIKNQGNRFLNILVVCSSG
HHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCCCCCEEEEEEEECCC
MGTSRLLSTRLEQVFSEIERITQASVSDLKSLDLSQYDGIISTVNLDIDSPYLTVNPLLP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCEEEEEEEECCCCEEEECCCCC
DSDISYVAQFLNTKSTFQETHDKSSNMIDKDDVHVETKDIDGNTSFENEQTSNLTSVFEK
CCCHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHH
HLSDEKSEQLMHHMRSGLTLLDSVKIVSTEVKQWQTYIADYLYQCDAIKDPTSFAELLEQ
HHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
RLIDNPGWILSPYPVAIPHLRDNMIKHPMILITVLEEPLALPSIQNDNQTIKYMISMFIP
HHCCCCCEEECCCCCCCCHHHHHHHCCCCEEEEEHHCCCCCCCCCCCCHHHHHHHHHHCC
DNDFMASLVSDLSEFLSLKLESIDTFMKNPQELETLLRNKFLERIKKQFI
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLLSTREKEMIALLIKYHGQYITIHDIAQQLAVSSRTIHRELKGVEAYLTSFSLTLERAN
CCCCCCHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KKGLRIAGENSDLNDLKQSIAQHQTIDLSVEEQKVIIIYALIQAKEPVKQYSLAQEIGVS
CCCCEEECCCCCHHHHHHHHHHCCEEEEEECCCEEEEEEEEHHCCCHHHHHHHHHHHCCC
VQTLAKMLDDLELYLNKYQLSLSRKRGEGIYLVGTESKKREFLSQLMVNNLNSTSVYSVI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHCCCCCHHHHHHH
ENHFVFHSLNQIHKDFVDLERIFNVERLLMDYLSALPYQLTESSYLTLTVHIVLSISRIK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCEEEEEHHHHHHHHHCC
NGEYVALNDDIYDSVQNTFEHKVASELADKLGQIYDVTFNQAEIDFITIHLRGAKRKNLN
CCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCEEEEEEEEEEECCCCCCCC
DTSLNNRCEENKIKAFVKKVEMISGMTFADLDTLVDGLTLHLNPAINRLQANIETYNPLT
CCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCEEEEECHHHHHHHHCCHHCCCHH
DMIKFKYPRLFENVRLALNDCWPDLIFPESEIAFIVLHFGGSIKNQGNRFLNILVVCSSG
HHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCCCCCEEEEEEEECCC
MGTSRLLSTRLEQVFSEIERITQASVSDLKSLDLSQYDGIISTVNLDIDSPYLTVNPLLP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCEEEEEEEECCCCEEEECCCCC
DSDISYVAQFLNTKSTFQETHDKSSNMIDKDDVHVETKDIDGNTSFENEQTSNLTSVFEK
CCCHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHH
HLSDEKSEQLMHHMRSGLTLLDSVKIVSTEVKQWQTYIADYLYQCDAIKDPTSFAELLEQ
HHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
RLIDNPGWILSPYPVAIPHLRDNMIKHPMILITVLEEPLALPSIQNDNQTIKYMISMFIP
HHCCCCCEEECCCCCCCCHHHHHHHCCCCEEEEEHHCCCCCCCCCCCCHHHHHHHHHHCC
DNDFMASLVSDLSEFLSLKLESIDTFMKNPQELETLLRNKFLERIKKQFI
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]