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The map label for this gene is alr

Identifier: 82751673

GI number: 82751673

Start: 2087509

End: 2088657

Strand: Reverse

Name: alr

Synonym: SAB1955c

Alternate gene names: 82751673

Gene position: 2088657-2087509 (Counterclockwise)

Preceding gene: 82751674

Following gene: 82751672

Centisome position: 76.16

GC content: 35.94

Gene sequence:

>1149_bases
ATGTCAGATAAATATTATAGATCTGCGTATATGAATGTAGATTTAAACGCTGTTGCATCAAATTTCAAAGTATTCAGTAC
ATTGCATCCAAATAAAACAGTGATGGCTGTCGTTAAAGCCAATGCCTATGGACTAGGTAGTGTTAAAGTAGCACGTCATT
TAATGGAAAATGGTGCCACATTTTTTGCTGTAGCAACGTTAGATGAAGCGATAGAACTTAGAATGCATGGGATTACTGCT
AAAATTTTAGTCTTAGGTGTGTTACCAGCTAAAGATATTGATAAAGCGATACAACACCGTGTTGCCTTAACGGTCCCGTC
TAAACAGTGGTTGAAAGAAGCAATTAAAAACATTTCTGATGAGCAAGAGAAAAAGTTATGGTTGCATATTAAATTAGATA
CAGGAATGGGACGTTTAGGTATTAAAGACACTAAAACGTATCAAGAAGTGATTGAAATCATTCAACAATATGAGCAACTT
GTATTTGAAGGCGTGTTTACACACTTTGTCTGCGCTGACGAACCAGGAGATATGACAACTGAACAATATCAACGTTTTAA
AGATATGGTCAATGAAGCAATTAAACCTGAATATATACATTGTCAGAACTCAGCAGGTTCTCTATTAATGGATTGCCAAT
TCTGTAATGCAATAAGACCAGGAATTTCCCTTTATGGATATTATCCATCAGAGTATGTACAGCAAAAAGTTAAAGTACAC
CTTAAACCAAGTGTGCAATTAATTGCTAATGTAGTTCAAACAAAGACGCTACAAGCGGGTGAGTCTGTAAGTTATGGTGC
AACTTATACAGCTACTGATCCAACAACAATAGCATTGTTACCTATTGGATACGCAGATGGCTATTTACGCATTATGCAAG
GTAGCTTTGTAAATGTAAATGGTCATCAATGCGAAGTTGTTGGTCGCGTATGTATGGATCAAACAATTGTAAAAGTGCCA
GATCAAGTTAAAGCTGGAGATTCGGTGATTTTAATAGATAATCATAGAGAAAGTCCACAGTCGGTAGAGGTGGCAGCTGA
AAAGCAACATACTATTAATTATGAAGTGCTTTGTAACTTGTCGAGACGTTTGCCGCGAATCTATCATGATGGTGATCAAC
GTTTTGTAACAAATGAATTGTTAAAATAA

Upstream 100 bases:

>100_bases
TGAGCCAAGTTGTTTTAGAAAAGTCAGCATTTTAAATTTGTTATACAATGATAATTGAGATCTAGTTTTAAAACGTGTGG
GAATTACAGGAGGAAGTAAT

Downstream 100 bases:

>100_bases
TATGGTCAGTGCATATAAAATTTGTTATCATTAGAGTAATTAAAGGTCATTTAATAACTTTTGGAATCAATTGGAGGTTC
TCATATGTTATCTTTTAGTC

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 382; Mature: 381

Protein sequence:

>382_residues
MSDKYYRSAYMNVDLNAVASNFKVFSTLHPNKTVMAVVKANAYGLGSVKVARHLMENGATFFAVATLDEAIELRMHGITA
KILVLGVLPAKDIDKAIQHRVALTVPSKQWLKEAIKNISDEQEKKLWLHIKLDTGMGRLGIKDTKTYQEVIEIIQQYEQL
VFEGVFTHFVCADEPGDMTTEQYQRFKDMVNEAIKPEYIHCQNSAGSLLMDCQFCNAIRPGISLYGYYPSEYVQQKVKVH
LKPSVQLIANVVQTKTLQAGESVSYGATYTATDPTTIALLPIGYADGYLRIMQGSFVNVNGHQCEVVGRVCMDQTIVKVP
DQVKAGDSVILIDNHRESPQSVEVAAEKQHTINYEVLCNLSRRLPRIYHDGDQRFVTNELLK

Sequences:

>Translated_382_residues
MSDKYYRSAYMNVDLNAVASNFKVFSTLHPNKTVMAVVKANAYGLGSVKVARHLMENGATFFAVATLDEAIELRMHGITA
KILVLGVLPAKDIDKAIQHRVALTVPSKQWLKEAIKNISDEQEKKLWLHIKLDTGMGRLGIKDTKTYQEVIEIIQQYEQL
VFEGVFTHFVCADEPGDMTTEQYQRFKDMVNEAIKPEYIHCQNSAGSLLMDCQFCNAIRPGISLYGYYPSEYVQQKVKVH
LKPSVQLIANVVQTKTLQAGESVSYGATYTATDPTTIALLPIGYADGYLRIMQGSFVNVNGHQCEVVGRVCMDQTIVKVP
DQVKAGDSVILIDNHRESPQSVEVAAEKQHTINYEVLCNLSRRLPRIYHDGDQRFVTNELLK
>Mature_381_residues
SDKYYRSAYMNVDLNAVASNFKVFSTLHPNKTVMAVVKANAYGLGSVKVARHLMENGATFFAVATLDEAIELRMHGITAK
ILVLGVLPAKDIDKAIQHRVALTVPSKQWLKEAIKNISDEQEKKLWLHIKLDTGMGRLGIKDTKTYQEVIEIIQQYEQLV
FEGVFTHFVCADEPGDMTTEQYQRFKDMVNEAIKPEYIHCQNSAGSLLMDCQFCNAIRPGISLYGYYPSEYVQQKVKVHL
KPSVQLIANVVQTKTLQAGESVSYGATYTATDPTTIALLPIGYADGYLRIMQGSFVNVNGHQCEVVGRVCMDQTIVKVPD
QVKAGDSVILIDNHRESPQSVEVAAEKQHTINYEVLCNLSRRLPRIYHDGDQRFVTNELLK

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1790487, Length=370, Percent_Identity=32.7027027027027, Blast_Score=158, Evalue=7e-40,
Organism=Escherichia coli, GI1787439, Length=369, Percent_Identity=31.9783197831978, Blast_Score=146, Evalue=3e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 42868; Mature: 42737

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDKYYRSAYMNVDLNAVASNFKVFSTLHPNKTVMAVVKANAYGLGSVKVARHLMENGAT
CCCCCEEHEEECCCHHHHHCCCEEEEEECCCCEEEEEEEECCCCCCHHHHHHHHHHCCCE
FFAVATLDEAIELRMHGITAKILVLGVLPAKDIDKAIQHRVALTVPSKQWLKEAIKNISD
EEEEEEHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHCEEEEECCCHHHHHHHHHCCCC
EQEKKLWLHIKLDTGMGRLGIKDTKTYQEVIEIIQQYEQLVFEGVFTHFVCADEPGDMTT
CCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCH
EQYQRFKDMVNEAIKPEYIHCQNSAGSLLMDCQFCNAIRPGISLYGYYPSEYVQQKVKVH
HHHHHHHHHHHHCCCCCEEEECCCCCCEEEEHHHHHHHCCCCEEEEECCHHHHHHHHEEE
LKPSVQLIANVVQTKTLQAGESVSYGATYTATDPTTIALLPIGYADGYLRIMQGSFVNVN
ECCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCEEEEEEECCCCCEEEEEECCEEECC
GHQCEVVGRVCMDQTIVKVPDQVKAGDSVILIDNHRESPQSVEVAAEKQHTINYEVLCNL
CCEEHHHHHHHHCCHHHCCCCCCCCCCEEEEEECCCCCCCHHEEEECHHHCCCHHHEECH
SRRLPRIYHDGDQRFVTNELLK
HHCCCCEEECCCCHHHHHHHCC
>Mature Secondary Structure 
SDKYYRSAYMNVDLNAVASNFKVFSTLHPNKTVMAVVKANAYGLGSVKVARHLMENGAT
CCCCEEHEEECCCHHHHHCCCEEEEEECCCCEEEEEEEECCCCCCHHHHHHHHHHCCCE
FFAVATLDEAIELRMHGITAKILVLGVLPAKDIDKAIQHRVALTVPSKQWLKEAIKNISD
EEEEEEHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHCEEEEECCCHHHHHHHHHCCCC
EQEKKLWLHIKLDTGMGRLGIKDTKTYQEVIEIIQQYEQLVFEGVFTHFVCADEPGDMTT
CCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCH
EQYQRFKDMVNEAIKPEYIHCQNSAGSLLMDCQFCNAIRPGISLYGYYPSEYVQQKVKVH
HHHHHHHHHHHHCCCCCEEEECCCCCCEEEEHHHHHHHCCCCEEEEECCHHHHHHHHEEE
LKPSVQLIANVVQTKTLQAGESVSYGATYTATDPTTIALLPIGYADGYLRIMQGSFVNVN
ECCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCEEEEEEECCCCCEEEEEECCEEECC
GHQCEVVGRVCMDQTIVKVPDQVKAGDSVILIDNHRESPQSVEVAAEKQHTINYEVLCNL
CCEEHHHHHHHHCCHHHCCCCCCCCCCEEEEEECCCCCCCHHEEEECHHHCCCHHHEECH
SRRLPRIYHDGDQRFVTNELLK
HHCCCCEEECCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9756984 [H]