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The map label for this gene is agrB

Identifier: 82751638

GI number: 82751638

Start: 2045592

End: 2046155

Strand: Direct

Name: agrB

Synonym: SAB1920

Alternate gene names: 82751638

Gene position: 2045592-2046155 (Clockwise)

Preceding gene: 82751637

Following gene: 82751639

Centisome position: 74.59

GC content: 25.53

Gene sequence:

>564_bases
TTGAATTATTTTGATAATAAAATTGACCAGTTTGCCACGTATCTTCAAAAGAGAAATAACTTAGATCATATTCAATTTTT
GCAAGTACGATTAGGGATGCAAATTATAGTTGGTAATTTTTTAAAAATACTTGTAACATATAGTATTTCTATATTCTTGA
GTGTATTTTTGTATACCTTAGTTACACACTTATCCTATATGTTAATACGCTATAATGCACATGGTGCTCATGCAAAGTCT
TCGATACTTTGTTACATACAAAGTATTTTAATATTTGTATTTGTACCTTATTTTCTAATTAATATAGACATTAATTTTAC
TTATTTACTGGCCTTATCTATTATAGGATTGATTTCCGTTGTTATTTATGCACCTGCAGCAACGAAAAAGCAACCTATAC
CTATAAAATTAGTAAAACGTAAAAAGTATGTATCTATAATTATGTATTTATTAGTTATGATTCTATCCTTAATAATACAT
CCATTTTATGCTCAATTTATGTTATTAGGAATTTTAGTAGAATCTATTACATTATTACCTATTTTTTTCCCTAAGGAGGA
TTAA

Upstream 100 bases:

>100_bases
TTACATTTAACAGTTAAGTATTTATTTCCTACAGTTAGGCAATATAATGATAAAAGATTGTACTAAATCGTATAATGACA
GTGAGGAGAGTGGTGTAAAA

Downstream 100 bases:

>100_bases
TCATGAATACACTTGTTAATATGTTTTTTGATTTTATAATTAAATTAGCTAAAGCAATCGGAATTGTCGGTGGCGTAAAC
GCTTGCAGCAGTTTATTTGA

Product: accessory gene regulator B

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MNYFDNKIDQFATYLQKRNNLDHIQFLQVRLGMQIIVGNFLKILVTYSISIFLSVFLYTLVTHLSYMLIRYNAHGAHAKS
SILCYIQSILIFVFVPYFLINIDINFTYLLALSIIGLISVVIYAPAATKKQPIPIKLVKRKKYVSIIMYLLVMILSLIIH
PFYAQFMLLGILVESITLLPIFFPKED

Sequences:

>Translated_187_residues
MNYFDNKIDQFATYLQKRNNLDHIQFLQVRLGMQIIVGNFLKILVTYSISIFLSVFLYTLVTHLSYMLIRYNAHGAHAKS
SILCYIQSILIFVFVPYFLINIDINFTYLLALSIIGLISVVIYAPAATKKQPIPIKLVKRKKYVSIIMYLLVMILSLIIH
PFYAQFMLLGILVESITLLPIFFPKED
>Mature_187_residues
MNYFDNKIDQFATYLQKRNNLDHIQFLQVRLGMQIIVGNFLKILVTYSISIFLSVFLYTLVTHLSYMLIRYNAHGAHAKS
SILCYIQSILIFVFVPYFLINIDINFTYLLALSIIGLISVVIYAPAATKKQPIPIKLVKRKKYVSIIMYLLVMILSLIIH
PFYAQFMLLGILVESITLLPIFFPKED

Specific function: Essential for the production of a quorum sensing system signal molecule, the autoinducing peptide (AIP). This quorum sensing system is responsible for the regulation of the expression of virulence factor genes. Involved in the proteolytic processing of Ag

COG id: COG4512

COG function: function code OTK; Membrane protein putatively involved in post-translational modification of the autoinducing quorum-sensing peptide

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AgrB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006741 [H]

Pfam domain/function: PF04647 AgrB [H]

EC number: NA

Molecular weight: Translated: 21679; Mature: 21679

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYFDNKIDQFATYLQKRNNLDHIQFLQVRLGMQIIVGNFLKILVTYSISIFLSVFLYTL
CCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTHLSYMLIRYNAHGAHAKSSILCYIQSILIFVFVPYFLINIDINFTYLLALSIIGLISV
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
VIYAPAATKKQPIPIKLVKRKKYVSIIMYLLVMILSLIIHPFYAQFMLLGILVESITLLP
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFFPKED
EECCCCC
>Mature Secondary Structure
MNYFDNKIDQFATYLQKRNNLDHIQFLQVRLGMQIIVGNFLKILVTYSISIFLSVFLYTL
CCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTHLSYMLIRYNAHGAHAKSSILCYIQSILIFVFVPYFLINIDINFTYLLALSIIGLISV
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
VIYAPAATKKQPIPIKLVKRKKYVSIIMYLLVMILSLIIHPFYAQFMLLGILVESITLLP
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFFPKED
EECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA