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The map label for this gene is pncA [H]

Identifier: 82751576

GI number: 82751576

Start: 1992543

End: 1993103

Strand: Direct

Name: pncA [H]

Synonym: SAB1855

Alternate gene names: 82751576

Gene position: 1992543-1993103 (Clockwise)

Preceding gene: 82751573

Following gene: 82751577

Centisome position: 72.65

GC content: 34.4

Gene sequence:

>561_bases
ATGACACATCGCGCACTATTAGTTGTTGACTATTCATATGACTTTATCGCAGACGACGGCTTACTAACATGCGGTAAACC
TGGACAAAATATTGAAGATTTTATTGTTTCTCGTATCAATGACTTTAATTATTATCAAGACCATATATTCTTTTTAATGG
ATTTACATTATTTACATGACAATCATCATCCTGAAAGTAAATTATTCCCACCACACAATATCGTAGATACAAGTGGTAGA
GAATTATACGGTAAAGTAGGTAAATTATACGAAACAATTAAAGCGCAACCTAATGTACATTTCATTGATAAAACGCGCTA
TGATTCGTTCTTTGGTACCCCGCTTGATAGTTTATTGAGAGAAAGAAGTATTAATCAAGTCGAAATCGTTGGTGTATGTA
CCGATATTTGTGTGTTACATACAGCAATTTCTGCATACAACTTAGGTTATAAAATTTCAGTACCTGCTGAGGGAGTGGCT
TCATTTAATCAAAAAGGGCATGAATGGGCACTTGCACATTTCAAAAACTCATTAGGTGCAGAGGTAGAACAACACGTTTA
A

Upstream 100 bases:

>100_bases
CTTAATCTATATTTATATATTAACCATTAGGGTTAAAAATTACTCTAGCATTTATGAATAGATGGGAGTTTATTTTATTA
TTATATAGGAGAGATGTTGA

Downstream 100 bases:

>100_bases
ATCGTGCTAAAATAATTATAAAGAATACAATATACAAGGGAGATATTTGACAATGGCTAAAACATATATTTTCGGACATA
AGAATCCAGACACTGATGCA

Product: bifunctional pyrazinamidase/nicotinamidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 186; Mature: 185

Protein sequence:

>186_residues
MTHRALLVVDYSYDFIADDGLLTCGKPGQNIEDFIVSRINDFNYYQDHIFFLMDLHYLHDNHHPESKLFPPHNIVDTSGR
ELYGKVGKLYETIKAQPNVHFIDKTRYDSFFGTPLDSLLRERSINQVEIVGVCTDICVLHTAISAYNLGYKISVPAEGVA
SFNQKGHEWALAHFKNSLGAEVEQHV

Sequences:

>Translated_186_residues
MTHRALLVVDYSYDFIADDGLLTCGKPGQNIEDFIVSRINDFNYYQDHIFFLMDLHYLHDNHHPESKLFPPHNIVDTSGR
ELYGKVGKLYETIKAQPNVHFIDKTRYDSFFGTPLDSLLRERSINQVEIVGVCTDICVLHTAISAYNLGYKISVPAEGVA
SFNQKGHEWALAHFKNSLGAEVEQHV
>Mature_185_residues
THRALLVVDYSYDFIADDGLLTCGKPGQNIEDFIVSRINDFNYYQDHIFFLMDLHYLHDNHHPESKLFPPHNIVDTSGRE
LYGKVGKLYETIKAQPNVHFIDKTRYDSFFGTPLDSLLRERSINQVEIVGVCTDICVLHTAISAYNLGYKISVPAEGVAS
FNQKGHEWALAHFKNSLGAEVEQHV

Specific function: Unknown

COG id: COG1335

COG function: function code Q; Amidases related to nicotinamidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the isochorismatase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000868 [H]

Pfam domain/function: PF00857 Isochorismatase [H]

EC number: NA

Molecular weight: Translated: 21200; Mature: 21069

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHRALLVVDYSYDFIADDGLLTCGKPGQNIEDFIVSRINDFNYYQDHIFFLMDLHYLHD
CCCEEEEEEECCCCEEECCCEEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHC
NHHPESKLFPPHNIVDTSGRELYGKVGKLYETIKAQPNVHFIDKTRYDSFFGTPLDSLLR
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHH
ERSINQVEIVGVCTDICVLHTAISAYNLGYKISVPAEGVASFNQKGHEWALAHFKNSLGA
HCCCCEEEEEHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHCCCCCHHHHHHHHHHHCC
EVEQHV
HHHHCC
>Mature Secondary Structure 
THRALLVVDYSYDFIADDGLLTCGKPGQNIEDFIVSRINDFNYYQDHIFFLMDLHYLHD
CCEEEEEEECCCCEEECCCEEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHC
NHHPESKLFPPHNIVDTSGRELYGKVGKLYETIKAQPNVHFIDKTRYDSFFGTPLDSLLR
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHH
ERSINQVEIVGVCTDICVLHTAISAYNLGYKISVPAEGVASFNQKGHEWALAHFKNSLGA
HCCCCEEEEEHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHCCCCCHHHHHHHHHHHCC
EVEQHV
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]