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The map label for this gene is dinB [H]

Identifier: 82751548

GI number: 82751548

Start: 1961004

End: 1961990

Strand: Reverse

Name: dinB [H]

Synonym: SAB1827c

Alternate gene names: 82751548

Gene position: 1961990-1961004 (Counterclockwise)

Preceding gene: 82751549

Following gene: 82751545

Centisome position: 71.54

GC content: 34.95

Gene sequence:

>987_bases
TTGACTGAGAGACGAATTATTCATATCGATATGGACTATTTTTTTGCACAAGTCGAAATGAGAGATAACCCCAAATTGAA
AGGGAAACCAGTCATTGTTGGTGGTAAAGCAAGTAGTAGGGGTGTTGTCTCTACGGCATCTTATGAAGCACGAAAATACG
GCGTCCATTCAGCAATGCCTATGTCACAAGCGCATAAATTATGTCCAAATGGATACTTTGTCACAAGTAATTTTGGTGCT
TACCGAGAAACATCTGCGCAGATTATGTCTATTTTCCGAAGTTATACAGATAAGGTAGAACCGATGTCATTGGATGAAGC
GTATTTAGATATTACAGAATTAGTGAGACCAGACCTTCCTGCTTCGAAAATTGCTCAGTATATTAGAAAAGATATTCTAG
AGAATACACATTTAACAGCATCTGCAGGTGTTTCTTATAACAAATTTTTAGCTAAATTAGCGAGTGGTATGAATAAACCT
TATGGTATGACTGTGATTGATTATCAAAATGTCCATGATATTTTGATGACATTGGATATTGGAGATTTTCCAGGCGTAGG
TAAAGCTTCCAAAAAAGTAATGCATGATAATGGTATTTTTAACGGTAGAGATTTATATGAGAAAACGGAATTTGAATTAA
TACGTTTGTTTGGAAAAAGAGGTCGGGGTTTATATAACAAGGCACGCGGTATTGACCATAGTGAAGTGAAATCATCAAGA
GTAAGAAAATCAGTAGGGACAGAGCGCACATTTGCAACAGACGTGAATGATGATGAGGAGATTTTAAGAAAAGTATGGGA
GTTGTCAGGTAAAACAGCTGAACGTCTAAATAAATTACAGAAGTCAGCTAAAACTGTAACGGTTAAAATTAAAACTTATC
AATTTGAAACGTTATCTAAACAGATGAGTTTAAGAGATTCGGTTAGTTCTGAAGAAGATATTTATAATATTGCATATTTA
CTTTATAACGATTTAAAAGACCCCTGA

Upstream 100 bases:

>100_bases
CTAAGTGCAAGATTTATGTAAAAAAATCGTACACAGCGTATAATTATGTTGAGATATTTTTGTGCGTTATAAAAGTAAAA
ATTAGTAGGGAGGTGAGCAC

Downstream 100 bases:

>100_bases
TGTACCAATTCGACTTATTGGTGTCACTGTAGGTAATTTAGAACAATCAACTTATAAAAATATGACGATATATGACTTTA
TATAAAATAAAGCTCCCTGC

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 328; Mature: 327

Protein sequence:

>328_residues
MTERRIIHIDMDYFFAQVEMRDNPKLKGKPVIVGGKASSRGVVSTASYEARKYGVHSAMPMSQAHKLCPNGYFVTSNFGA
YRETSAQIMSIFRSYTDKVEPMSLDEAYLDITELVRPDLPASKIAQYIRKDILENTHLTASAGVSYNKFLAKLASGMNKP
YGMTVIDYQNVHDILMTLDIGDFPGVGKASKKVMHDNGIFNGRDLYEKTEFELIRLFGKRGRGLYNKARGIDHSEVKSSR
VRKSVGTERTFATDVNDDEEILRKVWELSGKTAERLNKLQKSAKTVTVKIKTYQFETLSKQMSLRDSVSSEEDIYNIAYL
LYNDLKDP

Sequences:

>Translated_328_residues
MTERRIIHIDMDYFFAQVEMRDNPKLKGKPVIVGGKASSRGVVSTASYEARKYGVHSAMPMSQAHKLCPNGYFVTSNFGA
YRETSAQIMSIFRSYTDKVEPMSLDEAYLDITELVRPDLPASKIAQYIRKDILENTHLTASAGVSYNKFLAKLASGMNKP
YGMTVIDYQNVHDILMTLDIGDFPGVGKASKKVMHDNGIFNGRDLYEKTEFELIRLFGKRGRGLYNKARGIDHSEVKSSR
VRKSVGTERTFATDVNDDEEILRKVWELSGKTAERLNKLQKSAKTVTVKIKTYQFETLSKQMSLRDSVSSEEDIYNIAYL
LYNDLKDP
>Mature_327_residues
TERRIIHIDMDYFFAQVEMRDNPKLKGKPVIVGGKASSRGVVSTASYEARKYGVHSAMPMSQAHKLCPNGYFVTSNFGAY
RETSAQIMSIFRSYTDKVEPMSLDEAYLDITELVRPDLPASKIAQYIRKDILENTHLTASAGVSYNKFLAKLASGMNKPY
GMTVIDYQNVHDILMTLDIGDFPGVGKASKKVMHDNGIFNGRDLYEKTEFELIRLFGKRGRGLYNKARGIDHSEVKSSRV
RKSVGTERTFATDVNDDEEILRKVWELSGKTAERLNKLQKSAKTVTVKIKTYQFETLSKQMSLRDSVSSEEDIYNIAYLL
YNDLKDP

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI7706681, Length=339, Percent_Identity=30.3834808259587, Blast_Score=143, Evalue=2e-34,
Organism=Homo sapiens, GI84043967, Length=338, Percent_Identity=30.4733727810651, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI5729982, Length=349, Percent_Identity=29.7994269340974, Blast_Score=125, Evalue=8e-29,
Organism=Homo sapiens, GI154350220, Length=332, Percent_Identity=29.5180722891566, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI7705344, Length=126, Percent_Identity=46.031746031746, Blast_Score=112, Evalue=4e-25,
Organism=Escherichia coli, GI1786425, Length=298, Percent_Identity=45.9731543624161, Blast_Score=251, Evalue=6e-68,
Organism=Escherichia coli, GI1787432, Length=298, Percent_Identity=26.8456375838926, Blast_Score=91, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI193205700, Length=382, Percent_Identity=29.3193717277487, Blast_Score=134, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI17537959, Length=303, Percent_Identity=28.3828382838284, Blast_Score=117, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI115534089, Length=393, Percent_Identity=26.7175572519084, Blast_Score=107, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI193205702, Length=327, Percent_Identity=26.2996941896024, Blast_Score=83, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6324921, Length=206, Percent_Identity=30.0970873786408, Blast_Score=76, Evalue=8e-15,
Organism=Drosophila melanogaster, GI19923006, Length=342, Percent_Identity=27.7777777777778, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI21355641, Length=285, Percent_Identity=29.4736842105263, Blast_Score=114, Evalue=9e-26,
Organism=Drosophila melanogaster, GI24644984, Length=285, Percent_Identity=29.4736842105263, Blast_Score=114, Evalue=9e-26,
Organism=Drosophila melanogaster, GI24668444, Length=356, Percent_Identity=26.123595505618, Blast_Score=99, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 37167; Mature: 37036

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTERRIIHIDMDYFFAQVEMRDNPKLKGKPVIVGGKASSRGVVSTASYEARKYGVHSAMP
CCCCEEEEEEHHHEEEEEEECCCCCCCCCCEEEECCCCCCCCEEECCHHHHHHCCCCCCC
MSQAHKLCPNGYFVTSNFGAYRETSAQIMSIFRSYTDKVEPMSLDEAYLDITELVRPDLP
HHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCC
ASKIAQYIRKDILENTHLTASAGVSYNKFLAKLASGMNKPYGMTVIDYQNVHDILMTLDI
HHHHHHHHHHHHHCCCCCCHHCCCCHHHHHHHHHHCCCCCCCEEEEECCCHHHEEEEEEC
GDFPGVGKASKKVMHDNGIFNGRDLYEKTEFELIRLFGKRGRGLYNKARGIDHSEVKSSR
CCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHH
VRKSVGTERTFATDVNDDEEILRKVWELSGKTAERLNKLQKSAKTVTVKIKTYQFETLSK
HHHHHCCCCEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEEEEEEHHHHHH
QMSLRDSVSSEEDIYNIAYLLYNDLKDP
HHHHHHCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TERRIIHIDMDYFFAQVEMRDNPKLKGKPVIVGGKASSRGVVSTASYEARKYGVHSAMP
CCCEEEEEEHHHEEEEEEECCCCCCCCCCEEEECCCCCCCCEEECCHHHHHHCCCCCCC
MSQAHKLCPNGYFVTSNFGAYRETSAQIMSIFRSYTDKVEPMSLDEAYLDITELVRPDLP
HHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCC
ASKIAQYIRKDILENTHLTASAGVSYNKFLAKLASGMNKPYGMTVIDYQNVHDILMTLDI
HHHHHHHHHHHHHCCCCCCHHCCCCHHHHHHHHHHCCCCCCCEEEEECCCHHHEEEEEEC
GDFPGVGKASKKVMHDNGIFNGRDLYEKTEFELIRLFGKRGRGLYNKARGIDHSEVKSSR
CCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHH
VRKSVGTERTFATDVNDDEEILRKVWELSGKTAERLNKLQKSAKTVTVKIKTYQFETLSK
HHHHHCCCCEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEEEEEEHHHHHH
QMSLRDSVSSEEDIYNIAYLLYNDLKDP
HHHHHHCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA