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The map label for this gene is ptpA [H]

Identifier: 82751534

GI number: 82751534

Start: 1948510

End: 1948974

Strand: Direct

Name: ptpA [H]

Synonym: SAB1813

Alternate gene names: 82751534

Gene position: 1948510-1948974 (Clockwise)

Preceding gene: 82751530

Following gene: 82751535

Centisome position: 71.05

GC content: 33.76

Gene sequence:

>465_bases
ATGGTAGATGTAGCATTTGTCTGTCTTGGCAATATATGTCGTTCTCCAATGGCAGAAGCAATCATGCGACAAAGACTTAA
AGACAGAAATATTCATGATATAAAAGTACATTCAAGAGGTACTGGTAGCTGGAATTTAGGAGAGCCGCCTCATGAAGGTA
CACAAAAAATTCTTAACAAACACAATATTCCATTTGATGGCATGATTAGTGAATTATTCGAAGCGACAGATGATTTTGAT
TACATTGTGGCTATGGATCAAAGTAACGTTGATAATATTAAATTTATCAATCCTAATCTTAAGGGACAATTGTTCAAACT
GTTAGAATTTAGTAATATGGAAGAGAGTGATGTACCAGATCCATACTACACGAATAATTTTGAAGGTGTATACGACATGG
TATTATCATCTTGTGATAATTTAATAGACTACATCGTAAAAGATGCAAATTTGAAAGAGGGGTAG

Upstream 100 bases:

>100_bases
CAATTTAATAAACTTTAATAGAATTTTATATAATCTGCTTTCTTATTGTTTAAAGTCGCTATAAAATGGGGATATAACTA
CATAGTTTGGAGGAATCAAA

Downstream 100 bases:

>100_bases
TTTTTTATGGAAAATAAATTTGTTCCTGGTATTTTAATTGGTGCCGTAATTGGTGGCGCAATTAGTTTAGCTGATAAATC
TACACGTCAAGCTTTAGTTC

Product: protein tyrosine phosphatase

Products: NA

Alternate protein names: Phosphotyrosine phosphatase A; PTPase A [H]

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MVDVAFVCLGNICRSPMAEAIMRQRLKDRNIHDIKVHSRGTGSWNLGEPPHEGTQKILNKHNIPFDGMISELFEATDDFD
YIVAMDQSNVDNIKFINPNLKGQLFKLLEFSNMEESDVPDPYYTNNFEGVYDMVLSSCDNLIDYIVKDANLKEG

Sequences:

>Translated_154_residues
MVDVAFVCLGNICRSPMAEAIMRQRLKDRNIHDIKVHSRGTGSWNLGEPPHEGTQKILNKHNIPFDGMISELFEATDDFD
YIVAMDQSNVDNIKFINPNLKGQLFKLLEFSNMEESDVPDPYYTNNFEGVYDMVLSSCDNLIDYIVKDANLKEG
>Mature_154_residues
MVDVAFVCLGNICRSPMAEAIMRQRLKDRNIHDIKVHSRGTGSWNLGEPPHEGTQKILNKHNIPFDGMISELFEATDDFD
YIVAMDQSNVDNIKFINPNLKGQLFKLLEFSNMEESDVPDPYYTNNFEGVYDMVLSSCDNLIDYIVKDANLKEG

Specific function: Dephosphorylates the phosphotyrosine-containing proteins [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase family [H]

Homologues:

Organism=Homo sapiens, GI4757714, Length=147, Percent_Identity=34.0136054421769, Blast_Score=90, Evalue=8e-19,
Organism=Homo sapiens, GI6005988, Length=147, Percent_Identity=34.0136054421769, Blast_Score=80, Evalue=8e-16,
Organism=Escherichia coli, GI87081812, Length=136, Percent_Identity=26.4705882352941, Blast_Score=67, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6325330, Length=131, Percent_Identity=35.1145038167939, Blast_Score=85, Evalue=4e-18,
Organism=Drosophila melanogaster, GI78711846, Length=158, Percent_Identity=34.8101265822785, Blast_Score=95, Evalue=2e-20,
Organism=Drosophila melanogaster, GI78706770, Length=160, Percent_Identity=36.25, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI78706772, Length=160, Percent_Identity=36.25, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI78706766, Length=142, Percent_Identity=31.6901408450704, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI78706768, Length=142, Percent_Identity=31.6901408450704, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI78706764, Length=128, Percent_Identity=32.8125, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24648069, Length=149, Percent_Identity=29.5302013422819, Blast_Score=66, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000106
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 17551; Mature: 17551

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDVAFVCLGNICRSPMAEAIMRQRLKDRNIHDIKVHSRGTGSWNLGEPPHEGTQKILNK
CCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHH
HNIPFDGMISELFEATDDFDYIVAMDQSNVDNIKFINPNLKGQLFKLLEFSNMEESDVPD
CCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEECCCCHHHHHHHHHHCCCCCCCCCC
PYYTNNFEGVYDMVLSSCDNLIDYIVKDANLKEG
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MVDVAFVCLGNICRSPMAEAIMRQRLKDRNIHDIKVHSRGTGSWNLGEPPHEGTQKILNK
CCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHH
HNIPFDGMISELFEATDDFDYIVAMDQSNVDNIKFINPNLKGQLFKLLEFSNMEESDVPD
CCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEECCCCHHHHHHHHHHCCCCCCCCCC
PYYTNNFEGVYDMVLSSCDNLIDYIVKDANLKEG
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA