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The map label for this gene is prsA [H]

Identifier: 82751495

GI number: 82751495

Start: 1898293

End: 1899255

Strand: Direct

Name: prsA [H]

Synonym: SAB1774

Alternate gene names: 82751495

Gene position: 1898293-1899255 (Clockwise)

Preceding gene: 82751494

Following gene: 82751504

Centisome position: 69.22

GC content: 30.63

Gene sequence:

>963_bases
ATGAAGATGATAAACAAATTAATCGTTCCGGTAACAGCTAGTGCTCTATTATTAGGAGCTTGTGGCGCTAGTGCCACAGA
CTCTAAAGAAAATACATTAATTTCTTCTAAAGCTGGAGATGTAACAGTTGCAGATACAATGAAAAAAATCGGTAAAGATC
AAATTGCAAATGCATCATTTACTGAAATGTTAAATAAAATTTTAGCTGATAAATATAAAAATAAAGTTAATGATAAGAAG
ATTGACGAACAAATTGAAAAAATGCAAAAGCAATACGGCGGTAAAGATAAATTTGAAAAGGCCCTTCAACAGCAAGGTTT
AACAGCCGATAAATATAAAGAAAATTTACGTACTGCTGCTTATCATAAAGAATTACTATCAGATAAAATTAAAATCTCTG
ATTCTGAAATTAAAGAAGATAGCAAGAAAGCTTCACACATTTTAATTAAAGTTAAATCTAAGAAAAGCGACAAAGAAGGC
TTAGATGATAAAGAAGCGAAACAAAAAGCTGAAGAAATTCAAAAAGAAGTTTCAAAAGATCCAAGTAAATTTGGTGAAAT
CGCTAAAAAAGAATCAATGGATACTGGTTCAGCTAAAAAAGATGGCGAATTAGGTTATGTTCTTAAAGGACAAACTGATA
AAGATTTTGAAAAAGCACTATTTAAGCTTAAAGATGGTGAAGTATCAGACGTTGTTAAATCAAGCTTTGGATATCATATT
ATTAAAGCTGATAAACCAACAGACTTTAACAGTGAAAAACAAAGCCTGAAAGAAAAATTAGTCGATCAGAAAGTACAAAA
AAATCCAAAATTATTAACTGATGCATACAAAGATCTATTAAAAGAATACGATGTTGACTTTAAAGATCGTGATATTAAAT
CAGTTGTCGAAGATAAAATCTTAAACCCTGAAAAACTTAAACAAGGTGGCGCACAAGGCGGACAATCCGGCATGAGCCAA
TAA

Upstream 100 bases:

>100_bases
CTAAACCTAATGCTCTAGTCTGATGTCATGGGTTATTGATTGGTGATAATATAAAACTATGTTATATTCACGATGATTAA
CTTACAAAGGAGTTTCAACT

Downstream 100 bases:

>100_bases
CACAAAACCGAGCGACCGTGGTTCAAAAATCATACCACGGCCGCTCGGTTTTTTCGCATTAAAAATCGGACAGATGAGTT
CATGTTTCAGTATACTCATC

Product: peptidyl-prolyl cis-isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MKMINKLIVPVTASALLLGACGASATDSKENTLISSKAGDVTVADTMKKIGKDQIANASFTEMLNKILADKYKNKVNDKK
IDEQIEKMQKQYGGKDKFEKALQQQGLTADKYKENLRTAAYHKELLSDKIKISDSEIKEDSKKASHILIKVKSKKSDKEG
LDDKEAKQKAEEIQKEVSKDPSKFGEIAKKESMDTGSAKKDGELGYVLKGQTDKDFEKALFKLKDGEVSDVVKSSFGYHI
IKADKPTDFNSEKQSLKEKLVDQKVQKNPKLLTDAYKDLLKEYDVDFKDRDIKSVVEDKILNPEKLKQGGAQGGQSGMSQ

Sequences:

>Translated_320_residues
MKMINKLIVPVTASALLLGACGASATDSKENTLISSKAGDVTVADTMKKIGKDQIANASFTEMLNKILADKYKNKVNDKK
IDEQIEKMQKQYGGKDKFEKALQQQGLTADKYKENLRTAAYHKELLSDKIKISDSEIKEDSKKASHILIKVKSKKSDKEG
LDDKEAKQKAEEIQKEVSKDPSKFGEIAKKESMDTGSAKKDGELGYVLKGQTDKDFEKALFKLKDGEVSDVVKSSFGYHI
IKADKPTDFNSEKQSLKEKLVDQKVQKNPKLLTDAYKDLLKEYDVDFKDRDIKSVVEDKILNPEKLKQGGAQGGQSGMSQ
>Mature_320_residues
MKMINKLIVPVTASALLLGACGASATDSKENTLISSKAGDVTVADTMKKIGKDQIANASFTEMLNKILADKYKNKVNDKK
IDEQIEKMQKQYGGKDKFEKALQQQGLTADKYKENLRTAAYHKELLSDKIKISDSEIKEDSKKASHILIKVKSKKSDKEG
LDDKEAKQKAEEIQKEVSKDPSKFGEIAKKESMDTGSAKKDGELGYVLKGQTDKDFEKALFKLKDGEVSDVVKSSFGYHI
IKADKPTDFNSEKQSLKEKLVDQKVQKNPKLLTDAYKDLLKEYDVDFKDRDIKSVVEDKILNPEKLKQGGAQGGQSGMSQ

Specific function: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786238, Length=99, Percent_Identity=35.3535353535354, Blast_Score=65, Evalue=9e-12,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023059
- InterPro:   IPR000297
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 35624; Mature: 35624

Theoretical pI: Translated: 9.65; Mature: 9.65

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMINKLIVPVTASALLLGACGASATDSKENTLISSKAGDVTVADTMKKIGKDQIANASF
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCEEECCCCCCHHHHHHHHHHHHHHCCCHH
TEMLNKILADKYKNKVNDKKIDEQIEKMQKQYGGKDKFEKALQQQGLTADKYKENLRTAA
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHH
YHKELLSDKIKISDSEIKEDSKKASHILIKVKSKKSDKEGLDDKEAKQKAEEIQKEVSKD
HHHHHHHHHHCCCHHHHHHHHHHHHEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCC
PSKFGEIAKKESMDTGSAKKDGELGYVLKGQTDKDFEKALFKLKDGEVSDVVKSSFGYHI
HHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHCCCCHHHHHHHHHCCCEE
IKADKPTDFNSEKQSLKEKLVDQKVQKNPKLLTDAYKDLLKEYDVDFKDRDIKSVVEDKI
EECCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHC
LNPEKLKQGGAQGGQSGMSQ
CCHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MKMINKLIVPVTASALLLGACGASATDSKENTLISSKAGDVTVADTMKKIGKDQIANASF
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCEEECCCCCCHHHHHHHHHHHHHHCCCHH
TEMLNKILADKYKNKVNDKKIDEQIEKMQKQYGGKDKFEKALQQQGLTADKYKENLRTAA
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHH
YHKELLSDKIKISDSEIKEDSKKASHILIKVKSKKSDKEGLDDKEAKQKAEEIQKEVSKD
HHHHHHHHHHCCCHHHHHHHHHHHHEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCC
PSKFGEIAKKESMDTGSAKKDGELGYVLKGQTDKDFEKALFKLKDGEVSDVVKSSFGYHI
HHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHCCCCHHHHHHHHHCCCEE
IKADKPTDFNSEKQSLKEKLVDQKVQKNPKLLTDAYKDLLKEYDVDFKDRDIKSVVEDKI
EECCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHC
LNPEKLKQGGAQGGQSGMSQ
CCHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA