Click here to switch to the map view.

The map label for this gene is hysA1

Identifier: 82751389

GI number: 82751389

Start: 1803492

End: 1805915

Strand: Direct

Name: hysA1

Synonym: SAB1663

Alternate gene names: 82751389

Gene position: 1803492-1805915 (Clockwise)

Preceding gene: 82751383

Following gene: 82751397

Centisome position: 65.76

GC content: 31.02

Gene sequence:

>2424_bases
ATGACATATAAAATGAAGAAATGGCAAAAATTATCCACCATTACGTTATTAATGGCCGGAGTGATTACTTTAAATAATGG
TGAATTTAGAAATGTTGATAAACATCAAATCGCTGTGGCCGATACAAATGTTCAAACGCCAGATTATGAAAAATTGAAGA
AGACGTGGCTCGACGTTAACTACGGTAATGATCAGTATGATGAGAATAATCAAGATATGAAGAAGAAGTTTGATGCTAAA
GAAAATGAAGCTAAGAAGTTACTTGAAGATATGAAAACTGATACAAATAGAACATATTTGTGGTCAGGAGCTGAAAACCT
TGAAACTAATTCTTCTCACATGACAAAAACCTATCGTAATATCGAGAAAATCGCAGAAGCAATGCGACATAAAAATACTT
CATTAAAAACAGATGAAAACAAGTTGAAAATAAAAGATGCAATTAAGTGGTTACATCATAACGTATATGGTAAGGATCCA
GATAAGAAAGTCGCAGATTTAACCACCAATCGTAAAGAAAAAGATTCTAGTAAAAAGAATAACTCATTGAATTGGTGGGA
TTATGAAATTGGTACGCCAAGAGCATTAACAAATACACTACTTCTAATGGATAATATGCTCACTAAAGATGAAATGAAAA
ATTATTCAAAACCTATTAGTATATATTCACCATCCAGTTATAAAATTTTATCTTCTGTTGGTGAATCAGAAGATGCTAAA
GGTGGAAATTTAGTAGACATTGCTAAAGTAAAATTTTTAGAAAGTGTTATTGAAGAAGATGTAGATATGATGAAAAAGTC
TATAGATTCTTTTAATAAAGTGTTCACTTATGTTCAAGATTCTGCCACTGGTAAAGCTCGCAATGGATTCTATAAAGATG
GCTCTTACATTGATCATCAAGATGTCCCCTATACCGGTGCTTATGGCGTTGTTCTCTTAGAGGGAATTTCTCAAATGATG
CCGATGATAAAAGAATCTCCTTTTAAACATACACAAGATAAAGCTACATTAAGCAATTGGATTGACGAAGGTTTTATGCC
ACTAATCTATAAAGGTGAAATGATGGATTTATCACGTGGTAGAGCTATCAGTCGTGAAAATGAAACAAGTCATACAGCGT
CAGCGACTGTAATGAAATCATTGTTGAGATTGAGCGATACCATGGATGAGTCTACAAAAACAAAATATAAGCAAATCGTT
AAAACTTCTGTTAAATCTGATTCAAGTTATGACTCAAATGACACATTAAATTCTTATTCAGACATAGATAAAATGAAAAA
GTTAATGAATGATAGTACTATTTCTAAAAATGATTTAACACAACAACTTAAAATATATAATGACATGGATCGTGTCACCT
ATCACAACAAAGAATTAGACTTTGCATTTGGTTTAAGTATGACATCGAAAAACATCGCACGATACGAAAATATTAACGGA
GAGAACTTAAAAGGTTGGCACACCGGTGCAGGCATGTCTTATTTATATAACAGCGATGTCAAACACTATCGTGATAACTT
CTGGGCAACAGCCGATATGACTCGTCTTCCAGGCACTACTACTTTAAATGATATGCCATCTACTAATACTAAGAATGATA
AATCCTTTGTTGGCGGGACAAAATTAAATAATAAATACGCAAGCATCGGTATGGATTTTGAAAATCAGGACAAAACTTTA
ACTGCCAAAAAATCATATTTCATATTAAACGATAAAATTGTCTTCATAGGAACTGGCATTAAAAGTACTGATTCATCAAA
GAATCCAGTTACAAGTGTTGAAAATCGCAAAGCAAATGGGTATAAATTATTTAAAGGTGATATTGAAATTACCACTTCAG
ATGTTAATGCTCAGGAAACCCATTCAGTCTTTTTAGAGTCCAACGATACTAAAAAGAACATTGGTTATCATTTCTTAGAC
AAGCCAAAAATAACTGTAAAAAAAGAAAGTCATACTGGTAAGTGGAGTGAAATTAATAAAAGTCAAAAAACAGATGACAA
AAAAGATGAGTATTATGAAGTAACTCAAACACATAATACATCTGACAGTAAATATGCATATGTTTTGTATCCTGGTTTAT
CAAAAAGTGATTTTAAATCGAAGAATAATAATGTAAGTATTGTTAAACAAGATGAAGATTTTCATGTGATAAAAGATAAT
GATGGCGTATTTGCTGGGGTTAATTATAGTGATAGTACTAAATCTTTTGATATAAACGGAACTATTGTTGAATTAAAAGA
AAAAGGTATGTTTGTAATTAAAAAGAAAGATGATAACACATATGAATGTAGTTTTTATAATCCGACATCCACAAATTCCA
CTTCAAATAAAGAATCAAAAATTTCAGTTACAGGTTACACTATAACTAATCAAAGTGTCTCAAATTTTAAAGAATCTGAC
ATACACTTTGAATTAACTAAATAA

Upstream 100 bases:

>100_bases
TTTCCATGCATCAACGAATTTCCCAATCCTTTGGAAAGTTGAATTATTAATTAATCATAATATTACTTGCACACACGCAA
CACAAAAAGGAGACATGTTA

Downstream 100 bases:

>100_bases
GCAATAAAACCTCGGCACTATAACATTTTTATAGTGTCGAGGTTTTATAAATATTGCAAAATTTTATATCATAGTTAAGG
TCATCTATTGATTTATATAT

Product: hyaluronate lyase precursor

Products: NA

Alternate protein names: Hyaluronidase; HYase [H]

Number of amino acids: Translated: 807; Mature: 806

Protein sequence:

>807_residues
MTYKMKKWQKLSTITLLMAGVITLNNGEFRNVDKHQIAVADTNVQTPDYEKLKKTWLDVNYGNDQYDENNQDMKKKFDAK
ENEAKKLLEDMKTDTNRTYLWSGAENLETNSSHMTKTYRNIEKIAEAMRHKNTSLKTDENKLKIKDAIKWLHHNVYGKDP
DKKVADLTTNRKEKDSSKKNNSLNWWDYEIGTPRALTNTLLLMDNMLTKDEMKNYSKPISIYSPSSYKILSSVGESEDAK
GGNLVDIAKVKFLESVIEEDVDMMKKSIDSFNKVFTYVQDSATGKARNGFYKDGSYIDHQDVPYTGAYGVVLLEGISQMM
PMIKESPFKHTQDKATLSNWIDEGFMPLIYKGEMMDLSRGRAISRENETSHTASATVMKSLLRLSDTMDESTKTKYKQIV
KTSVKSDSSYDSNDTLNSYSDIDKMKKLMNDSTISKNDLTQQLKIYNDMDRVTYHNKELDFAFGLSMTSKNIARYENING
ENLKGWHTGAGMSYLYNSDVKHYRDNFWATADMTRLPGTTTLNDMPSTNTKNDKSFVGGTKLNNKYASIGMDFENQDKTL
TAKKSYFILNDKIVFIGTGIKSTDSSKNPVTSVENRKANGYKLFKGDIEITTSDVNAQETHSVFLESNDTKKNIGYHFLD
KPKITVKKESHTGKWSEINKSQKTDDKKDEYYEVTQTHNTSDSKYAYVLYPGLSKSDFKSKNNNVSIVKQDEDFHVIKDN
DGVFAGVNYSDSTKSFDINGTIVELKEKGMFVIKKKDDNTYECSFYNPTSTNSTSNKESKISVTGYTITNQSVSNFKESD
IHFELTK

Sequences:

>Translated_807_residues
MTYKMKKWQKLSTITLLMAGVITLNNGEFRNVDKHQIAVADTNVQTPDYEKLKKTWLDVNYGNDQYDENNQDMKKKFDAK
ENEAKKLLEDMKTDTNRTYLWSGAENLETNSSHMTKTYRNIEKIAEAMRHKNTSLKTDENKLKIKDAIKWLHHNVYGKDP
DKKVADLTTNRKEKDSSKKNNSLNWWDYEIGTPRALTNTLLLMDNMLTKDEMKNYSKPISIYSPSSYKILSSVGESEDAK
GGNLVDIAKVKFLESVIEEDVDMMKKSIDSFNKVFTYVQDSATGKARNGFYKDGSYIDHQDVPYTGAYGVVLLEGISQMM
PMIKESPFKHTQDKATLSNWIDEGFMPLIYKGEMMDLSRGRAISRENETSHTASATVMKSLLRLSDTMDESTKTKYKQIV
KTSVKSDSSYDSNDTLNSYSDIDKMKKLMNDSTISKNDLTQQLKIYNDMDRVTYHNKELDFAFGLSMTSKNIARYENING
ENLKGWHTGAGMSYLYNSDVKHYRDNFWATADMTRLPGTTTLNDMPSTNTKNDKSFVGGTKLNNKYASIGMDFENQDKTL
TAKKSYFILNDKIVFIGTGIKSTDSSKNPVTSVENRKANGYKLFKGDIEITTSDVNAQETHSVFLESNDTKKNIGYHFLD
KPKITVKKESHTGKWSEINKSQKTDDKKDEYYEVTQTHNTSDSKYAYVLYPGLSKSDFKSKNNNVSIVKQDEDFHVIKDN
DGVFAGVNYSDSTKSFDINGTIVELKEKGMFVIKKKDDNTYECSFYNPTSTNSTSNKESKISVTGYTITNQSVSNFKESD
IHFELTK
>Mature_806_residues
TYKMKKWQKLSTITLLMAGVITLNNGEFRNVDKHQIAVADTNVQTPDYEKLKKTWLDVNYGNDQYDENNQDMKKKFDAKE
NEAKKLLEDMKTDTNRTYLWSGAENLETNSSHMTKTYRNIEKIAEAMRHKNTSLKTDENKLKIKDAIKWLHHNVYGKDPD
KKVADLTTNRKEKDSSKKNNSLNWWDYEIGTPRALTNTLLLMDNMLTKDEMKNYSKPISIYSPSSYKILSSVGESEDAKG
GNLVDIAKVKFLESVIEEDVDMMKKSIDSFNKVFTYVQDSATGKARNGFYKDGSYIDHQDVPYTGAYGVVLLEGISQMMP
MIKESPFKHTQDKATLSNWIDEGFMPLIYKGEMMDLSRGRAISRENETSHTASATVMKSLLRLSDTMDESTKTKYKQIVK
TSVKSDSSYDSNDTLNSYSDIDKMKKLMNDSTISKNDLTQQLKIYNDMDRVTYHNKELDFAFGLSMTSKNIARYENINGE
NLKGWHTGAGMSYLYNSDVKHYRDNFWATADMTRLPGTTTLNDMPSTNTKNDKSFVGGTKLNNKYASIGMDFENQDKTLT
AKKSYFILNDKIVFIGTGIKSTDSSKNPVTSVENRKANGYKLFKGDIEITTSDVNAQETHSVFLESNDTKKNIGYHFLDK
PKITVKKESHTGKWSEINKSQKTDDKKDEYYEVTQTHNTSDSKYAYVLYPGLSKSDFKSKNNNVSIVKQDEDFHVIKDND
GVFAGVNYSDSTKSFDINGTIVELKEKGMFVIKKKDDNTYECSFYNPTSTNSTSNKESKISVTGYTITNQSVSNFKESDI
HFELTK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the polysaccharide lyase 8 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008929
- InterPro:   IPR011013
- InterPro:   IPR014718
- InterPro:   IPR011071
- InterPro:   IPR012970
- InterPro:   IPR004103
- InterPro:   IPR003159
- InterPro:   IPR012329 [H]

Pfam domain/function: PF02278 Lyase_8; PF02884 Lyase_8_C; PF08124 Lyase_8_N [H]

EC number: =4.2.2.1 [H]

Molecular weight: Translated: 92071; Mature: 91940

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYKMKKWQKLSTITLLMAGVITLNNGEFRNVDKHQIAVADTNVQTPDYEKLKKTWLDVN
CCCCCCHHHHHHHHHHHHHCEEEECCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHEEEC
YGNDQYDENNQDMKKKFDAKENEAKKLLEDMKTDTNRTYLWSGAENLETNSSHMTKTYRN
CCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHH
IEKIAEAMRHKNTSLKTDENKLKIKDAIKWLHHNVYGKDPDKKVADLTTNRKEKDSSKKN
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCHHCCCCCC
NSLNWWDYEIGTPRALTNTLLLMDNMLTKDEMKNYSKPISIYSPSSYKILSSVGESEDAK
CCCCEEEEECCCCHHHHHHHHHHHHHCCHHHHHHCCCCEEEECCCCHHHHHHCCCCCCCC
GGNLVDIAKVKFLESVIEEDVDMMKKSIDSFNKVFTYVQDSATGKARNGFYKDGSYIDHQ
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
DVPYTGAYGVVLLEGISQMMPMIKESPFKHTQDKATLSNWIDEGFMPLIYKGEMMDLSRG
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCEEEECCEEECCCC
RAISRENETSHTASATVMKSLLRLSDTMDESTKTKYKQIVKTSVKSDSSYDSNDTLNSYS
CCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHH
DIDKMKKLMNDSTISKNDLTQQLKIYNDMDRVTYHNKELDFAFGLSMTSKNIARYENING
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHEECCCCCCEEECCCCCCCHHHHHCCCCC
ENLKGWHTGAGMSYLYNSDVKHYRDNFWATADMTRLPGTTTLNDMPSTNTKNDKSFVGGT
CCCCCEECCCCCCEEECCCHHHHHHCEEEECCCCCCCCCCCCCCCCCCCCCCCCCEECCC
KLNNKYASIGMDFENQDKTLTAKKSYFILNDKIVFIGTGIKSTDSSKNPVTSVENRKANG
CCCCCEEEEECCCCCCCCEEEEECEEEEEECEEEEEECCCCCCCCCCCCCCCCCCCCCCC
YKLFKGDIEITTSDVNAQETHSVFLESNDTKKNIGYHFLDKPKITVKKESHTGKWSEINK
EEEEECCEEEEECCCCCCCCEEEEEECCCCCCCCCEEEECCCCEEEEECCCCCCHHHCCC
SQKTDDKKDEYYEVTQTHNTSDSKYAYVLYPGLSKSDFKSKNNNVSIVKQDEDFHVIKDN
CCCCCCCCCHHEEEEECCCCCCCEEEEEEECCCCCHHCCCCCCCEEEEEECCCEEEEECC
DGVFAGVNYSDSTKSFDINGTIVELKEKGMFVIKKKDDNTYECSFYNPTSTNSTSNKESK
CCEEEECCCCCCCCEEECCCEEEEEECCCEEEEEECCCCEEEEEEECCCCCCCCCCCCCE
ISVTGYTITNQSVSNFKESDIHFELTK
EEEEEEEEECCHHHCCCCCCEEEEECC
>Mature Secondary Structure 
TYKMKKWQKLSTITLLMAGVITLNNGEFRNVDKHQIAVADTNVQTPDYEKLKKTWLDVN
CCCCCHHHHHHHHHHHHHCEEEECCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHEEEC
YGNDQYDENNQDMKKKFDAKENEAKKLLEDMKTDTNRTYLWSGAENLETNSSHMTKTYRN
CCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHH
IEKIAEAMRHKNTSLKTDENKLKIKDAIKWLHHNVYGKDPDKKVADLTTNRKEKDSSKKN
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCHHCCCCCC
NSLNWWDYEIGTPRALTNTLLLMDNMLTKDEMKNYSKPISIYSPSSYKILSSVGESEDAK
CCCCEEEEECCCCHHHHHHHHHHHHHCCHHHHHHCCCCEEEECCCCHHHHHHCCCCCCCC
GGNLVDIAKVKFLESVIEEDVDMMKKSIDSFNKVFTYVQDSATGKARNGFYKDGSYIDHQ
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
DVPYTGAYGVVLLEGISQMMPMIKESPFKHTQDKATLSNWIDEGFMPLIYKGEMMDLSRG
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCEEEECCEEECCCC
RAISRENETSHTASATVMKSLLRLSDTMDESTKTKYKQIVKTSVKSDSSYDSNDTLNSYS
CCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHH
DIDKMKKLMNDSTISKNDLTQQLKIYNDMDRVTYHNKELDFAFGLSMTSKNIARYENING
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHEECCCCCCEEECCCCCCCHHHHHCCCCC
ENLKGWHTGAGMSYLYNSDVKHYRDNFWATADMTRLPGTTTLNDMPSTNTKNDKSFVGGT
CCCCCEECCCCCCEEECCCHHHHHHCEEEECCCCCCCCCCCCCCCCCCCCCCCCCEECCC
KLNNKYASIGMDFENQDKTLTAKKSYFILNDKIVFIGTGIKSTDSSKNPVTSVENRKANG
CCCCCEEEEECCCCCCCCEEEEECEEEEEECEEEEEECCCCCCCCCCCCCCCCCCCCCCC
YKLFKGDIEITTSDVNAQETHSVFLESNDTKKNIGYHFLDKPKITVKKESHTGKWSEINK
EEEEECCEEEEECCCCCCCCEEEEEECCCCCCCCCEEEECCCCEEEEECCCCCCHHHCCC
SQKTDDKKDEYYEVTQTHNTSDSKYAYVLYPGLSKSDFKSKNNNVSIVKQDEDFHVIKDN
CCCCCCCCCHHEEEEECCCCCCCEEEEEEECCCCCHHCCCCCCCEEEEEECCCEEEEECC
DGVFAGVNYSDSTKSFDINGTIVELKEKGMFVIKKKDDNTYECSFYNPTSTNSTSNKESK
CCEEEECCCCCCCCEEECCCEEEEEECCCEEEEEECCCCEEEEEEECCCCCCCCCCCCCE
ISVTGYTITNQSVSNFKESDIHFELTK
EEEEEEEEECCHHHCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7557301 [H]