Click here to switch to the map view.

The map label for this gene is murC

Identifier: 82751329

GI number: 82751329

Start: 1736957

End: 1738195

Strand: Reverse

Name: murC

Synonym: SAB1600c

Alternate gene names: 82751329

Gene position: 1738195-1736957 (Counterclockwise)

Preceding gene: 82751330

Following gene: 82751328

Centisome position: 63.38

GC content: 31.07

Gene sequence:

>1239_bases
ATGAAGTTCAAGGATCGGATATTGAGAACTACGTATTTACAGACAGTTGCTCTTAGAAATAAGGGGATAAAAATATTACC
ATTTGGTGCTAATAACATAAAAGAAGATATGGTAGTTATACAAGGTAATGCATTCGCGAGTAGCCATGAAGAAATAGTAC
GTGCACATCAATTGAAATTAGATGTTGTAAGTTATAATGATTTTTTAGGACAGATTATTGATCAATATACTTCAGTAGCT
GTAACTGGTGCACATGGTAAAACTTCTACAACAGGTTTATTATCACATGTTATGAATGGTGATAAAAAGACTTCATTTTT
AATTGGTGATGGCACAGGTATGGGATTGCCTGAAAGTGATTATTTCGCTTTTGAGGCATGTGAATATAGACGTCACTTTT
TAAGTTATAAACCTGATTACGCAATTATGACAAATATTGATTTCGATCATCCTGATTATTTCAAAGATATTAATGATGTT
TTTGATGCATTCCAAGAAATGGCACATAATGTTAAAAAAGGTATTATTGCTTGGGGTGATGATGAACATCTATGTAAAAT
AGAAGCAGATGTTCCAATTTATTACTATGGATTTAAAGATTCGGATGACATTTATGCTCAAAATATTCAAATTACGGATA
AAGGTACTGCTTTTGATGTGTATGTGGATGGTGAGTTTTATGATCACTTCTTGTCTCCACAATATGGTGACCATACAGTT
TTAAATGCATTAGCTGTAATTGCGATTAGTTATTTAGAGAAGCTAGATGTTACAAATATTAAAGAAGCATTAGAAACGTT
TGGTGGTGTTAAACGTCGTTTCAATGAAACTACAATTGCAAATCAAGTTATCGTAGATGATTATGCACACCATCCAAGAG
AAATTAGTGCTACAATTGAAACAGCACGAAAAAAATATCCACATAAAGAAGTTGTTGCAGTATTTCAACCACACACTTTC
TCTAGAACACAAGCATTTTTAAATGAATTTGCAGAAAGTTTAAGTAAAGCAGATCGTGTATTCTTATGTGAAATTTTTGG
ATCAATTAGAGAAAATACTGGCGCATTAACGATACAAGATTTAATTGATAAAATTGAAGGTGCATCGTTAATTAATGAAG
ATTCTATTAATGTATTAGAACAATTTGATAATGCTGTTGTTTTATTTATGGGTGCAGGTGATATTCAAAAATTACAAAAT
GCATATTTAGATAAATTAGGCATGAAAAATGCGTTTTAA

Upstream 100 bases:

>100_bases
ATTATGAGTAAGGAGTTTTATATAATGACACACTATCATTTTGTCGGAATTAAAGGTTCTGGCATGAGTTCATTAGCACA
AATCATGCATGATTTAGGAC

Downstream 100 bases:

>100_bases
TATGTTTATAATAGAGTAGTATGGGTATTTATTATTAATGACATTATTACATGTTAATTAGGAGGCGTTTTTAATGGATT
GGATTTTACCAATTGCTGGA

Product: UDP-N-acetylmuramate--L-alanine ligase

Products: NA

Alternate protein names: UDP-N-acetylmuramoyl-L-alanine synthetase [H]

Number of amino acids: Translated: 412; Mature: 412

Protein sequence:

>412_residues
MKFKDRILRTTYLQTVALRNKGIKILPFGANNIKEDMVVIQGNAFASSHEEIVRAHQLKLDVVSYNDFLGQIIDQYTSVA
VTGAHGKTSTTGLLSHVMNGDKKTSFLIGDGTGMGLPESDYFAFEACEYRRHFLSYKPDYAIMTNIDFDHPDYFKDINDV
FDAFQEMAHNVKKGIIAWGDDEHLCKIEADVPIYYYGFKDSDDIYAQNIQITDKGTAFDVYVDGEFYDHFLSPQYGDHTV
LNALAVIAISYLEKLDVTNIKEALETFGGVKRRFNETTIANQVIVDDYAHHPREISATIETARKKYPHKEVVAVFQPHTF
SRTQAFLNEFAESLSKADRVFLCEIFGSIRENTGALTIQDLIDKIEGASLINEDSINVLEQFDNAVVLFMGAGDIQKLQN
AYLDKLGMKNAF

Sequences:

>Translated_412_residues
MKFKDRILRTTYLQTVALRNKGIKILPFGANNIKEDMVVIQGNAFASSHEEIVRAHQLKLDVVSYNDFLGQIIDQYTSVA
VTGAHGKTSTTGLLSHVMNGDKKTSFLIGDGTGMGLPESDYFAFEACEYRRHFLSYKPDYAIMTNIDFDHPDYFKDINDV
FDAFQEMAHNVKKGIIAWGDDEHLCKIEADVPIYYYGFKDSDDIYAQNIQITDKGTAFDVYVDGEFYDHFLSPQYGDHTV
LNALAVIAISYLEKLDVTNIKEALETFGGVKRRFNETTIANQVIVDDYAHHPREISATIETARKKYPHKEVVAVFQPHTF
SRTQAFLNEFAESLSKADRVFLCEIFGSIRENTGALTIQDLIDKIEGASLINEDSINVLEQFDNAVVLFMGAGDIQKLQN
AYLDKLGMKNAF
>Mature_412_residues
MKFKDRILRTTYLQTVALRNKGIKILPFGANNIKEDMVVIQGNAFASSHEEIVRAHQLKLDVVSYNDFLGQIIDQYTSVA
VTGAHGKTSTTGLLSHVMNGDKKTSFLIGDGTGMGLPESDYFAFEACEYRRHFLSYKPDYAIMTNIDFDHPDYFKDINDV
FDAFQEMAHNVKKGIIAWGDDEHLCKIEADVPIYYYGFKDSDDIYAQNIQITDKGTAFDVYVDGEFYDHFLSPQYGDHTV
LNALAVIAISYLEKLDVTNIKEALETFGGVKRRFNETTIANQVIVDDYAHHPREISATIETARKKYPHKEVVAVFQPHTF
SRTQAFLNEFAESLSKADRVFLCEIFGSIRENTGALTIQDLIDKIEGASLINEDSINVLEQFDNAVVLFMGAGDIQKLQN
AYLDKLGMKNAF

Specific function: Cell wall formation [H]

COG id: COG0773

COG function: function code M; UDP-N-acetylmuramate-alanine ligase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MurCDEF family [H]

Homologues:

Organism=Escherichia coli, GI1786279, Length=384, Percent_Identity=29.1666666666667, Blast_Score=131, Evalue=1e-31,
Organism=Escherichia coli, GI1790680, Length=349, Percent_Identity=27.7936962750716, Blast_Score=114, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004101
- InterPro:   IPR013221
- InterPro:   IPR000713
- InterPro:   IPR016040
- InterPro:   IPR005758 [H]

Pfam domain/function: PF01225 Mur_ligase; PF02875 Mur_ligase_C; PF08245 Mur_ligase_M [H]

EC number: =6.3.2.8 [H]

Molecular weight: Translated: 46511; Mature: 46511

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFKDRILRTTYLQTVALRNKGIKILPFGANNIKEDMVVIQGNAFASSHEEIVRAHQLKL
CCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCEEEEECCCCCCHHHHHHHHHHHEE
DVVSYNDFLGQIIDQYTSVAVTGAHGKTSTTGLLSHVMNGDKKTSFLIGDGTGMGLPESD
EEECHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCC
YFAFEACEYRRHFLSYKPDYAIMTNIDFDHPDYFKDINDVFDAFQEMAHNVKKGIIAWGD
CHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEECC
DEHLCKIEADVPIYYYGFKDSDDIYAQNIQITDKGTAFDVYVDGEFYDHFLSPQYGDHTV
CCCEEEEECCCEEEEECCCCCCCEEEEEEEEECCCCEEEEEECCHHHHHHCCCCCCCHHH
LNALAVIAISYLEKLDVTNIKEALETFGGVKRRFNETTIANQVIVDDYAHHPREISATIE
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCHHHHHHHHEEHHHCCCCHHHHHHHH
TARKKYPHKEVVAVFQPHTFSRTQAFLNEFAESLSKADRVFLCEIFGSIRENTGALTIQD
HHHHHCCCHHEEEEECCCCHHHHHHHHHHHHHHHHHHCCEEHHHHHHHHHCCCCCEEHHH
LIDKIEGASLINEDSINVLEQFDNAVVLFMGAGDIQKLQNAYLDKLGMKNAF
HHHHHCCCCCCCCCHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKFKDRILRTTYLQTVALRNKGIKILPFGANNIKEDMVVIQGNAFASSHEEIVRAHQLKL
CCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCEEEEECCCCCCHHHHHHHHHHHEE
DVVSYNDFLGQIIDQYTSVAVTGAHGKTSTTGLLSHVMNGDKKTSFLIGDGTGMGLPESD
EEECHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCC
YFAFEACEYRRHFLSYKPDYAIMTNIDFDHPDYFKDINDVFDAFQEMAHNVKKGIIAWGD
CHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEECC
DEHLCKIEADVPIYYYGFKDSDDIYAQNIQITDKGTAFDVYVDGEFYDHFLSPQYGDHTV
CCCEEEEECCCEEEEECCCCCCCEEEEEEEEECCCCEEEEEECCHHHHHHCCCCCCCHHH
LNALAVIAISYLEKLDVTNIKEALETFGGVKRRFNETTIANQVIVDDYAHHPREISATIE
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCHHHHHHHHEEHHHCCCCHHHHHHHH
TARKKYPHKEVVAVFQPHTFSRTQAFLNEFAESLSKADRVFLCEIFGSIRENTGALTIQD
HHHHHCCCHHEEEEECCCCHHHHHHHHHHHHHHHHHHCCEEHHHHHHHHHCCCCCEEHHH
LIDKIEGASLINEDSINVLEQFDNAVVLFMGAGDIQKLQNAYLDKLGMKNAF
HHHHHCCCCCCCCCHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA