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The map label for this gene is acuC

Identifier: 82751324

GI number: 82751324

Start: 1730788

End: 1731957

Strand: Direct

Name: acuC

Synonym: SAB1595

Alternate gene names: 82751324

Gene position: 1730788-1731957 (Clockwise)

Preceding gene: 82751323

Following gene: 82751335

Centisome position: 63.11

GC content: 34.53

Gene sequence:

>1170_bases
ATGCAACAACATTCATCAAAAACTGCATATGTTTATTCAGATAAGTTATTACAATATCGATTTCATGACCAACATCCCTT
CAATCAAATGCGTTTAAAATTAACAACAGAGCTACTTTTGAATGCAAATTTGTTGTCTCCAGAACAAATAGTACAACCTA
GAATTGCAACAGATGACGAATTAATGTTAATTCATAAATATGATTACGTCGAAGCAATTAAGCATGCTTCACATGGCATT
ATCAGTGAAGATGAGGCTAAGAAATATGGATTAAATGATGAAGAGAATGGTCAATTTAAGCATATGCACCGCCATAGTGC
CACAATTGTTGGAGGCGCTTTAACTTTAGCAGATCTTATTATGTCAGGCAAAGTATTAAATGGTTGTCACTTAGGTGGTG
GTTTGCATCACGCTCAACCTGGTCGAGCAAGTGGTTTTTGTATATACAATGATATTGCAATTACCGCACAATACTTAGCT
AAAGAATACAATCAACGCGTTTTAATCATAGATACCGATGCACATCATGGAGATGGTACACAATGGAGTTTCTATGCCGA
TAACCATGTTATTACTTATTCTATCCATGAAACCGGAAAATTTCTTTTCCCAGGCTCTGGTCACTATACTGAGCGCGGTG
AAGATATCGGCTATGGACACACTGTTAATGTCCCACTTGAACCGTATACAGAAGATGCATCATTTTTGGAGTGTTTTAAA
TTAACAGTTGAGCCTGTCGTAAAGAGTTTTAAACCTGATATTATTCTAAGCGTAAATGGTGTCGATATACATTATCGTGA
TCCACTAACTCATCTAAATTGTACTTTACATTCATTATATGAAATTCCATATTTTGTAAAATATTTAGCTGATACTTATA
CGAATGGAAAGGTAATTATGTTTGGTGGCGGAGGTTACAATATTTGGAGAGTCGTACCACGTGCATGGAGTCATGTATTC
TTAAGTTTAATTGATCAACCAATTCAAAGTGGTTATTTACCGTTAGAATGGATTAATAAATGGAAGCATTATTCATCTGA
ATTATTACCTAAAAGATGGGAAGATCGTTTAAATGATTATACCTATGTCCCCCGCACAAAAGAAATTAGTGAAAAAAATA
AAAAATTAGCTTTACATATAGCGAGTTGGTACGAATCTACTCTCCAATAA

Upstream 100 bases:

>100_bases
AATTGGCAAAAATATTACATTAGAACAGCAACAAGCGTTTGATGATATTCGTTATATGAATCGGTTTTTCTTTTAATTTT
TGGATTATCGGAGGGATTAT

Downstream 100 bases:

>100_bases
GTCACCTAATCTGCAACGATTTTAAAAGATAAATAAAAGGCATTCTTCCAACACCCGTATAATTCGGGTCGCTAGATGAA
TGCCTAATTTTGTGAATTTA

Product: acetoin utilization protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MQQHSSKTAYVYSDKLLQYRFHDQHPFNQMRLKLTTELLLNANLLSPEQIVQPRIATDDELMLIHKYDYVEAIKHASHGI
ISEDEAKKYGLNDEENGQFKHMHRHSATIVGGALTLADLIMSGKVLNGCHLGGGLHHAQPGRASGFCIYNDIAITAQYLA
KEYNQRVLIIDTDAHHGDGTQWSFYADNHVITYSIHETGKFLFPGSGHYTERGEDIGYGHTVNVPLEPYTEDASFLECFK
LTVEPVVKSFKPDIILSVNGVDIHYRDPLTHLNCTLHSLYEIPYFVKYLADTYTNGKVIMFGGGGYNIWRVVPRAWSHVF
LSLIDQPIQSGYLPLEWINKWKHYSSELLPKRWEDRLNDYTYVPRTKEISEKNKKLALHIASWYESTLQ

Sequences:

>Translated_389_residues
MQQHSSKTAYVYSDKLLQYRFHDQHPFNQMRLKLTTELLLNANLLSPEQIVQPRIATDDELMLIHKYDYVEAIKHASHGI
ISEDEAKKYGLNDEENGQFKHMHRHSATIVGGALTLADLIMSGKVLNGCHLGGGLHHAQPGRASGFCIYNDIAITAQYLA
KEYNQRVLIIDTDAHHGDGTQWSFYADNHVITYSIHETGKFLFPGSGHYTERGEDIGYGHTVNVPLEPYTEDASFLECFK
LTVEPVVKSFKPDIILSVNGVDIHYRDPLTHLNCTLHSLYEIPYFVKYLADTYTNGKVIMFGGGGYNIWRVVPRAWSHVF
LSLIDQPIQSGYLPLEWINKWKHYSSELLPKRWEDRLNDYTYVPRTKEISEKNKKLALHIASWYESTLQ
>Mature_389_residues
MQQHSSKTAYVYSDKLLQYRFHDQHPFNQMRLKLTTELLLNANLLSPEQIVQPRIATDDELMLIHKYDYVEAIKHASHGI
ISEDEAKKYGLNDEENGQFKHMHRHSATIVGGALTLADLIMSGKVLNGCHLGGGLHHAQPGRASGFCIYNDIAITAQYLA
KEYNQRVLIIDTDAHHGDGTQWSFYADNHVITYSIHETGKFLFPGSGHYTERGEDIGYGHTVNVPLEPYTEDASFLECFK
LTVEPVVKSFKPDIILSVNGVDIHYRDPLTHLNCTLHSLYEIPYFVKYLADTYTNGKVIMFGGGGYNIWRVVPRAWSHVF
LSLIDQPIQSGYLPLEWINKWKHYSSELLPKRWEDRLNDYTYVPRTKEISEKNKKLALHIASWYESTLQ

Specific function: Role in growth on acetoin or butanediol. Involved in the breakdown of these compounds used as a carbon source [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI13128860, Length=328, Percent_Identity=32.0121951219512, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI13128862, Length=388, Percent_Identity=28.3505154639175, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI30795202, Length=340, Percent_Identity=29.7058823529412, Blast_Score=135, Evalue=7e-32,
Organism=Homo sapiens, GI30795204, Length=340, Percent_Identity=29.7058823529412, Blast_Score=135, Evalue=8e-32,
Organism=Homo sapiens, GI17158039, Length=340, Percent_Identity=29.7058823529412, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI293336691, Length=323, Percent_Identity=31.2693498452012, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI13128864, Length=377, Percent_Identity=28.1167108753316, Blast_Score=129, Evalue=6e-30,
Organism=Homo sapiens, GI8923769, Length=311, Percent_Identity=26.3665594855305, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI62750349, Length=337, Percent_Identity=30.2670623145401, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI62750347, Length=337, Percent_Identity=30.2670623145401, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI20070354, Length=272, Percent_Identity=28.6764705882353, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI153085395, Length=213, Percent_Identity=31.924882629108, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI169234807, Length=134, Percent_Identity=40.2985074626866, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI148539870, Length=134, Percent_Identity=40.2985074626866, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI262073092, Length=208, Percent_Identity=28.3653846153846, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI262073088, Length=225, Percent_Identity=27.1111111111111, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI226529806, Length=238, Percent_Identity=29.4117647058824, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI217272877, Length=290, Percent_Identity=25.1724137931034, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI209862883, Length=289, Percent_Identity=24.2214532871972, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17561978, Length=385, Percent_Identity=29.8701298701299, Blast_Score=148, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI17508561, Length=337, Percent_Identity=29.080118694362, Blast_Score=145, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI17534739, Length=318, Percent_Identity=30.188679245283, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17540334, Length=312, Percent_Identity=29.8076923076923, Blast_Score=115, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI193209491, Length=241, Percent_Identity=33.195020746888, Blast_Score=115, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17540332, Length=306, Percent_Identity=30.0653594771242, Blast_Score=115, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI193206283, Length=306, Percent_Identity=30.0653594771242, Blast_Score=114, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI17537347, Length=285, Percent_Identity=28.7719298245614, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI25154020, Length=356, Percent_Identity=24.438202247191, Blast_Score=85, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI25154022, Length=368, Percent_Identity=23.9130434782609, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI193207430, Length=292, Percent_Identity=24.6575342465753, Blast_Score=65, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6321244, Length=322, Percent_Identity=32.2981366459627, Blast_Score=158, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6323999, Length=313, Percent_Identity=29.073482428115, Blast_Score=143, Evalue=5e-35,
Organism=Saccharomyces cerevisiae, GI6324307, Length=335, Percent_Identity=28.0597014925373, Blast_Score=121, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6325325, Length=227, Percent_Identity=29.0748898678414, Blast_Score=102, Evalue=8e-23,
Organism=Drosophila melanogaster, GI24657891, Length=321, Percent_Identity=33.6448598130841, Blast_Score=157, Evalue=1e-38,
Organism=Drosophila melanogaster, GI24644244, Length=336, Percent_Identity=30.952380952381, Blast_Score=150, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24642144, Length=339, Percent_Identity=27.4336283185841, Blast_Score=119, Evalue=4e-27,
Organism=Drosophila melanogaster, GI24642142, Length=339, Percent_Identity=27.4336283185841, Blast_Score=119, Evalue=5e-27,
Organism=Drosophila melanogaster, GI24642146, Length=339, Percent_Identity=27.4336283185841, Blast_Score=119, Evalue=5e-27,
Organism=Drosophila melanogaster, GI281360899, Length=346, Percent_Identity=27.1676300578035, Blast_Score=118, Evalue=6e-27,
Organism=Drosophila melanogaster, GI281360801, Length=356, Percent_Identity=28.9325842696629, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24641720, Length=339, Percent_Identity=29.2035398230088, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI281360799, Length=339, Percent_Identity=29.2035398230088, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24649807, Length=288, Percent_Identity=27.4305555555556, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003085
- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 44613; Mature: 44613

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQHSSKTAYVYSDKLLQYRFHDQHPFNQMRLKLTTELLLNANLLSPEQIVQPRIATDDE
CCCCCCCEEEEEECHHEEEEECCCCCHHHHHHHEEEHHHHCCCCCCHHHHHCCCCCCCCC
LMLIHKYDYVEAIKHASHGIISEDEAKKYGLNDEENGQFKHMHRHSATIVGGALTLADLI
EEEEEECHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCCHHHHHCCCEEEHHHHHHHHHH
MSGKVLNGCHLGGGLHHAQPGRASGFCIYNDIAITAQYLAKEYNQRVLIIDTDAHHGDGT
HCCCEECCEECCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHCCEEEEEECCCCCCCCC
QWSFYADNHVITYSIHETGKFLFPGSGHYTERGEDIGYGHTVNVPLEPYTEDASFLECFK
EEEEEECCEEEEEEEECCCCEEECCCCCCCCCCCCCCCCCEEECCCCCCCCCHHHHHHHH
LTVEPVVKSFKPDIILSVNGVDIHYRDPLTHLNCTLHSLYEIPYFVKYLADTYTNGKVIM
HHHHHHHHHCCCCEEEEECCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
FGGGGYNIWRVVPRAWSHVFLSLIDQPIQSGYLPLEWINKWKHYSSELLPKRWEDRLNDY
ECCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCHHHHHHHCCCC
TYVPRTKEISEKNKKLALHIASWYESTLQ
EECCCCHHHHCCCCEEEEEEEHHHHHHCC
>Mature Secondary Structure
MQQHSSKTAYVYSDKLLQYRFHDQHPFNQMRLKLTTELLLNANLLSPEQIVQPRIATDDE
CCCCCCCEEEEEECHHEEEEECCCCCHHHHHHHEEEHHHHCCCCCCHHHHHCCCCCCCCC
LMLIHKYDYVEAIKHASHGIISEDEAKKYGLNDEENGQFKHMHRHSATIVGGALTLADLI
EEEEEECHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCCHHHHHCCCEEEHHHHHHHHHH
MSGKVLNGCHLGGGLHHAQPGRASGFCIYNDIAITAQYLAKEYNQRVLIIDTDAHHGDGT
HCCCEECCEECCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHCCEEEEEECCCCCCCCC
QWSFYADNHVITYSIHETGKFLFPGSGHYTERGEDIGYGHTVNVPLEPYTEDASFLECFK
EEEEEECCEEEEEEEECCCCEEECCCCCCCCCCCCCCCCCEEECCCCCCCCCHHHHHHHH
LTVEPVVKSFKPDIILSVNGVDIHYRDPLTHLNCTLHSLYEIPYFVKYLADTYTNGKVIM
HHHHHHHHHCCCCEEEEECCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
FGGGGYNIWRVVPRAWSHVFLSLIDQPIQSGYLPLEWINKWKHYSSELLPKRWEDRLNDY
ECCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCHHHHHHHCCCC
TYVPRTKEISEKNKKLALHIASWYESTLQ
EECCCCHHHHCCCCEEEEEEEHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA