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The map label for this gene is coaE

Identifier: 82751276

GI number: 82751276

Start: 1668191

End: 1668814

Strand: Reverse

Name: coaE

Synonym: SAB1547c

Alternate gene names: 82751276

Gene position: 1668814-1668191 (Counterclockwise)

Preceding gene: 82751277

Following gene: 82751275

Centisome position: 60.85

GC content: 34.13

Gene sequence:

>624_bases
ATGCCGAAAGTTATTGGTCTAACAGGTGGAATCGCCTCAGGAAAATCAACAGTATCAGAACTCTTATCCGTATTCGGTTT
TAAAGTAGTAGATGCTGATAAAGCAGCCAGGGAAGCTGTTAAAAAGGGGAGTAAAGGTTTAGCTCAAGTACGAGAAGTCT
TTGGTGATGAAGCAATTGATGAAAATGGTGAGATGAATCGTCGTTATATGGGGGATTTAGTTTTTAACCATCCAGAAAAA
CGCTTAGAATTAAATGCTATCATACATCCTATCGTGCGAGATATTATGGAAGAAGAAAAGCAAGAATATTTAAAACAAGG
ATATAATGTAATCATGGATATTCCATTATTATTTGAAAATGAATTGGAAAATACAGTAGACGAAGTGTGGGTTATATACA
CTTCTGAAAGTATACAAATGGATCGTTTAATGCAACGTAATAATTTGTCATTAGAAGATGCGAAAGCTCGTGTCTATAGC
CAAATTTCTATTGATAAAAAAAGCCGAATGGCCGATCATGTTATCGATAATTTAGGGGATAAACTTGAATTAAAACAAAA
CCTTGAGAGATTGTTAAAAGAAGAAGGTTATATTGAAAAGCCGAATTACGGAGAAGAAGATTAA

Upstream 100 bases:

>100_bases
GGTTTGCAAAGTGTGTGGAAGTCAAATTGAAACAAAAATCATCGCGACAAGAAATAGTCATTATTGTCCTGTATGTCAAA
AATAAAGAAAGAGTGAAATT

Downstream 100 bases:

>100_bases
TATTACACTATAAATAAGTCATTACTTTACGTTCGCGCTGATGTATGTAAGTAATGACTATTTTTTATAAAAAAGATAAA
TAAATCAACGGAAAACGCTT

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 207; Mature: 206

Protein sequence:

>207_residues
MPKVIGLTGGIASGKSTVSELLSVFGFKVVDADKAAREAVKKGSKGLAQVREVFGDEAIDENGEMNRRYMGDLVFNHPEK
RLELNAIIHPIVRDIMEEEKQEYLKQGYNVIMDIPLLFENELENTVDEVWVIYTSESIQMDRLMQRNNLSLEDAKARVYS
QISIDKKSRMADHVIDNLGDKLELKQNLERLLKEEGYIEKPNYGEED

Sequences:

>Translated_207_residues
MPKVIGLTGGIASGKSTVSELLSVFGFKVVDADKAAREAVKKGSKGLAQVREVFGDEAIDENGEMNRRYMGDLVFNHPEK
RLELNAIIHPIVRDIMEEEKQEYLKQGYNVIMDIPLLFENELENTVDEVWVIYTSESIQMDRLMQRNNLSLEDAKARVYS
QISIDKKSRMADHVIDNLGDKLELKQNLERLLKEEGYIEKPNYGEED
>Mature_206_residues
PKVIGLTGGIASGKSTVSELLSVFGFKVVDADKAAREAVKKGSKGLAQVREVFGDEAIDENGEMNRRYMGDLVFNHPEKR
LELNAIIHPIVRDIMEEEKQEYLKQGYNVIMDIPLLFENELENTVDEVWVIYTSESIQMDRLMQRNNLSLEDAKARVYSQ
ISIDKKSRMADHVIDNLGDKLELKQNLERLLKEEGYIEKPNYGEED

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=179, Percent_Identity=45.8100558659218, Blast_Score=164, Evalue=5e-41,
Organism=Homo sapiens, GI191252795, Length=179, Percent_Identity=45.8100558659218, Blast_Score=164, Evalue=5e-41,
Organism=Homo sapiens, GI110227607, Length=161, Percent_Identity=32.9192546583851, Blast_Score=91, Evalue=5e-19,
Organism=Homo sapiens, GI110227605, Length=161, Percent_Identity=32.9192546583851, Blast_Score=91, Evalue=8e-19,
Organism=Homo sapiens, GI110227603, Length=161, Percent_Identity=32.9192546583851, Blast_Score=91, Evalue=8e-19,
Organism=Homo sapiens, GI110227601, Length=161, Percent_Identity=32.9192546583851, Blast_Score=91, Evalue=8e-19,
Organism=Homo sapiens, GI205277394, Length=161, Percent_Identity=32.9192546583851, Blast_Score=91, Evalue=8e-19,
Organism=Escherichia coli, GI1786292, Length=191, Percent_Identity=33.5078534031414, Blast_Score=110, Evalue=7e-26,
Organism=Caenorhabditis elegans, GI17554944, Length=201, Percent_Identity=35.3233830845771, Blast_Score=135, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI25143409, Length=165, Percent_Identity=32.7272727272727, Blast_Score=76, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6320402, Length=197, Percent_Identity=38.0710659898477, Blast_Score=129, Evalue=4e-31,
Organism=Drosophila melanogaster, GI24644728, Length=179, Percent_Identity=39.1061452513966, Blast_Score=129, Evalue=9e-31,
Organism=Drosophila melanogaster, GI24658602, Length=167, Percent_Identity=31.1377245508982, Blast_Score=88, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 23636; Mature: 23505

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKVIGLTGGIASGKSTVSELLSVFGFKVVDADKAAREAVKKGSKGLAQVREVFGDEAID
CCCEEECCCCCCCCHHHHHHHHHHHCCHHCCHHHHHHHHHHCCCHHHHHHHHHHCCHHCC
ENGEMNRRYMGDLVFNHPEKRLELNAIIHPIVRDIMEEEKQEYLKQGYNVIMDIPLLFEN
CCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHH
ELENTVDEVWVIYTSESIQMDRLMQRNNLSLEDAKARVYSQISIDKKSRMADHVIDNLGD
HHHHHHHHEEEEECCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
KLELKQNLERLLKEEGYIEKPNYGEED
HHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
PKVIGLTGGIASGKSTVSELLSVFGFKVVDADKAAREAVKKGSKGLAQVREVFGDEAID
CCEEECCCCCCCCHHHHHHHHHHHCCHHCCHHHHHHHHHHCCCHHHHHHHHHHCCHHCC
ENGEMNRRYMGDLVFNHPEKRLELNAIIHPIVRDIMEEEKQEYLKQGYNVIMDIPLLFEN
CCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHH
ELENTVDEVWVIYTSESIQMDRLMQRNNLSLEDAKARVYSQISIDKKSRMADHVIDNLGD
HHHHHHHHEEEEECCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
KLELKQNLERLLKEEGYIEKPNYGEED
HHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA