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The map label for this gene is hemX [H]

Identifier: 82751260

GI number: 82751260

Start: 1650620

End: 1651435

Strand: Reverse

Name: hemX [H]

Synonym: SAB1531c

Alternate gene names: 82751260

Gene position: 1651435-1650620 (Counterclockwise)

Preceding gene: 82751261

Following gene: 82751259

Centisome position: 60.22

GC content: 28.43

Gene sequence:

>816_bases
ATGCAAGAAAACCTGTTTATTCGATTCAATGAAATTATATTATTAATATACTTAATCAGTATCATTTGCTATTTTTATGA
TTTTGTCCAAAAAAGTCATAAGATTAGAAGTTTAGGCATATATTTATTGGGGATTGTTTGGGTTTTACAAACAATCTCTT
TATCTATTTTTATTATACAAACTAGACATATTCCATTAGGGTCTATTTCAGATGTATTCTATACTTTAAGTTGGCTGATT
ATTTCAATCTCTTTAATTCTTAACCTTATCAAAGTTTTGAATTTCTCTGTGTTTTTCTTGAATTTAATAGGGTTAACCCT
TTTAGGGATGAATACATTTCAACCGACACATTATACCAATAAGGTTCAGAAAATTGCTGTTGTAGACGAGTTACTGTTAG
TCCATATTGGTCTAGCTGTGTTAAGTTATGTCTTCTTTGCCTTAGCTTTTGTCAATGCATTACTGTATATCATGCAATAC
CGTAATTTGAAGGAAAAGCGTTTTGATCAAAAATACTTTAGAATAGGTAGCGTTGCTACACTTGAATCAATTGTGTTTTA
CTCAACGTTAAGTGGGTGGATAATTCTCATATTTAGTATTATTTTAGGTACACAGTGGGGTGTGATTTCAGTTGGTGAAC
GTATATTCATTGACCCGAAGGTAATACTATCTTCAATTATTACAGTATTATATGGAAGTTATATTTTACTTAGAATCAAC
AAATGGTTGAATTCAAGGTATTTAATATACTATAACATTATTTTATTTTGCTTAAATATGATTAATTTATTTTTTGCAAC
ACATTTTGTGAATTGA

Upstream 100 bases:

>100_bases
TCCTCATGAGCAAGCGAAGCAACAAAAAGAAAGCAAGGTCAAGGAAATTTCAGCGCGACGTATCTTTAGTTTTGAATAAG
CATATTAATATGGTGATAAT

Downstream 100 bases:

>100_bases
GAAAATAATCTAGAGCAATCCGTTCCTAGGAGGAATTGAACATGCGTAAATTAGTCGTTGGCTCCAGAAGAAGTAAATTA
GCTTTAACACAAAGCCAGCA

Product: membrane uroporphyrinogen III methylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 271; Mature: 271

Protein sequence:

>271_residues
MQENLFIRFNEIILLIYLISIICYFYDFVQKSHKIRSLGIYLLGIVWVLQTISLSIFIIQTRHIPLGSISDVFYTLSWLI
ISISLILNLIKVLNFSVFFLNLIGLTLLGMNTFQPTHYTNKVQKIAVVDELLLVHIGLAVLSYVFFALAFVNALLYIMQY
RNLKEKRFDQKYFRIGSVATLESIVFYSTLSGWIILIFSIILGTQWGVISVGERIFIDPKVILSSIITVLYGSYILLRIN
KWLNSRYLIYYNIILFCLNMINLFFATHFVN

Sequences:

>Translated_271_residues
MQENLFIRFNEIILLIYLISIICYFYDFVQKSHKIRSLGIYLLGIVWVLQTISLSIFIIQTRHIPLGSISDVFYTLSWLI
ISISLILNLIKVLNFSVFFLNLIGLTLLGMNTFQPTHYTNKVQKIAVVDELLLVHIGLAVLSYVFFALAFVNALLYIMQY
RNLKEKRFDQKYFRIGSVATLESIVFYSTLSGWIILIFSIILGTQWGVISVGERIFIDPKVILSSIITVLYGSYILLRIN
KWLNSRYLIYYNIILFCLNMINLFFATHFVN
>Mature_271_residues
MQENLFIRFNEIILLIYLISIICYFYDFVQKSHKIRSLGIYLLGIVWVLQTISLSIFIIQTRHIPLGSISDVFYTLSWLI
ISISLILNLIKVLNFSVFFLNLIGLTLLGMNTFQPTHYTNKVQKIAVVDELLLVHIGLAVLSYVFFALAFVNALLYIMQY
RNLKEKRFDQKYFRIGSVATLESIVFYSTLSGWIILIFSIILGTQWGVISVGERIFIDPKVILSSIITVLYGSYILLRIN
KWLNSRYLIYYNIILFCLNMINLFFATHFVN

Specific function: Required for hemL synthesis [H]

COG id: COG0755

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To M.leprae U1620K [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002541 [H]

Pfam domain/function: PF01578 Cytochrom_C_asm [H]

EC number: NA

Molecular weight: Translated: 31547; Mature: 31547

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQENLFIRFNEIILLIYLISIICYFYDFVQKSHKIRSLGIYLLGIVWVLQTISLSIFIIQ
CCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEE
TRHIPLGSISDVFYTLSWLIISISLILNLIKVLNFSVFFLNLIGLTLLGMNTFQPTHYTN
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
KVQKIAVVDELLLVHIGLAVLSYVFFALAFVNALLYIMQYRNLKEKRFDQKYFRIGSVAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCHHH
LESIVFYSTLSGWIILIFSIILGTQWGVISVGERIFIDPKVILSSIITVLYGSYILLRIN
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCEEEECHHHHHHHHHHHHHHHHHHHHHH
KWLNSRYLIYYNIILFCLNMINLFFATHFVN
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQENLFIRFNEIILLIYLISIICYFYDFVQKSHKIRSLGIYLLGIVWVLQTISLSIFIIQ
CCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEE
TRHIPLGSISDVFYTLSWLIISISLILNLIKVLNFSVFFLNLIGLTLLGMNTFQPTHYTN
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
KVQKIAVVDELLLVHIGLAVLSYVFFALAFVNALLYIMQYRNLKEKRFDQKYFRIGSVAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCHHH
LESIVFYSTLSGWIILIFSIILGTQWGVISVGERIFIDPKVILSSIITVLYGSYILLRIN
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCEEEECHHHHHHHHHHHHHHHHHHHHHH
KWLNSRYLIYYNIILFCLNMINLFFATHFVN
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2110138; 8969504; 9384377 [H]