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The map label for this gene is obgE

Identifier: 82751242

GI number: 82751242

Start: 1632949

End: 1634241

Strand: Reverse

Name: obgE

Synonym: SAB1513c

Alternate gene names: 82751242

Gene position: 1634241-1632949 (Counterclockwise)

Preceding gene: 82751243

Following gene: 82751241

Centisome position: 59.59

GC content: 36.74

Gene sequence:

>1293_bases
ATGTTTGTCGATCAAGTTAAAATATCTCTTAAAGCCGGTGATGGTGGTAATGGTATTACCGCATACAGAAGAGAAAAATA
TGTACCATTTGGTGGACCAGCTGGCGGTGACGGTGGTAAAGGTGCTTCAGTCGTATTTGAAGTGGATGAAGGTTCAAGAA
CGTTATTAGATTTTAGATATCAACGTCATTTTAAAGCAAGCAAAGGTGAAAATGGCCAAAGTAGTAATATGCATGGTAAA
AATGCGGAAGATTTAGTATTAAAAGTTCCACCTGGTACAATTATTAAAAATGTTGAAACAGACGAAGTGTTAGCAGATCT
TGTTGAAGATGGTCAAAGAGCTGTAGTAGCGAAGGGCGGTCGAGGTGGCCGAGGTAATTCACGTTTTGCAACACCTAGAA
ACCCTGCACCTGACTTCAGTGAAAAAGGCGAACCAGGTGAGGAATTAGATGTATCTTTAGAATTGAAATTATTAGCTGAT
GTAGGATTAGTAGGTTTCCCTAGTGTGGGTAAATCGACTTTATTATCTATCGTTTCAAAAGCTAAGCCTAAAATTGGGGC
ATATCATTTTACAACGATTAAACCAAATCTAGGTGTTGTTTCAGCACCTGATCAACGAAGTTTTGTTATGGCAGATTTAC
CAGGTTTAATTGAAGGTGCATCTGACGGCGTTGGATTAGGACATCAATTTTTAAGACATGTAGAGAGAACAAAAGTTATT
GTTCACATGATTGATATGAGTGGTTCTGAAGGTAGAGAACCTATTGAAGATTATAAAGTCATTAATCAAGAATTAGCCGC
GTACGAGCAACGTTTAGAAGATAGACCTCAAATCGTAGTAGCTAACAAGATGGATTTACCTGAATCACAAGATAATTTAA
TCTTATTTAAAGAAGAAATTGGCGAAGATGTGCCAGTTATTCCAGTTTCAACAATAACGCGTGATAATATTGATCAATTA
TTATATGCAATAGCAGATAAATTAGAAGAATATAAAGATGTTGACTTCACAGTTGAAGAAGAGGAGTCGGTTGGCATTAA
CCGAGTATTATATAAACATACACCGTCACAAGATAAATTTACAATTTTAAGAGATGATGATGGTGCTTATGTGGTAAGTG
GTAATGCTATTGAAAGAATGTTTAAAATGACTGACTTTAACAGTGATCCAGCAGTACGTCGATTTGCTCGTCAAATGCGT
TCGATGGGTATTGATGATGCGCTTAGAGAACGTGGTTGTAAAAATGGTGATATCGTTAGAATTCTTGGCGGAGAATTTGA
ATTCGTTGAATAG

Upstream 100 bases:

>100_bases
CAACTGCATAAGAGCCCCTAATTATTTACAATATATAAGGGGCTCTAATATGCTATAATTATTGGGAAAATGAAAATTAT
ATGTAAAAGAGGTGAGATAT

Downstream 100 bases:

>100_bases
GAGCGTAACATGATGGACAATAAAGATTATAAAAAGTTTTATTTAATTAGAGAAGATGTCTTGCCTGAATCCGTGGTTAA
AACATTGAAGATTAAAGATG

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg [H]

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MFVDQVKISLKAGDGGNGITAYRREKYVPFGGPAGGDGGKGASVVFEVDEGSRTLLDFRYQRHFKASKGENGQSSNMHGK
NAEDLVLKVPPGTIIKNVETDEVLADLVEDGQRAVVAKGGRGGRGNSRFATPRNPAPDFSEKGEPGEELDVSLELKLLAD
VGLVGFPSVGKSTLLSIVSKAKPKIGAYHFTTIKPNLGVVSAPDQRSFVMADLPGLIEGASDGVGLGHQFLRHVERTKVI
VHMIDMSGSEGREPIEDYKVINQELAAYEQRLEDRPQIVVANKMDLPESQDNLILFKEEIGEDVPVIPVSTITRDNIDQL
LYAIADKLEEYKDVDFTVEEEESVGINRVLYKHTPSQDKFTILRDDDGAYVVSGNAIERMFKMTDFNSDPAVRRFARQMR
SMGIDDALRERGCKNGDIVRILGGEFEFVE

Sequences:

>Translated_430_residues
MFVDQVKISLKAGDGGNGITAYRREKYVPFGGPAGGDGGKGASVVFEVDEGSRTLLDFRYQRHFKASKGENGQSSNMHGK
NAEDLVLKVPPGTIIKNVETDEVLADLVEDGQRAVVAKGGRGGRGNSRFATPRNPAPDFSEKGEPGEELDVSLELKLLAD
VGLVGFPSVGKSTLLSIVSKAKPKIGAYHFTTIKPNLGVVSAPDQRSFVMADLPGLIEGASDGVGLGHQFLRHVERTKVI
VHMIDMSGSEGREPIEDYKVINQELAAYEQRLEDRPQIVVANKMDLPESQDNLILFKEEIGEDVPVIPVSTITRDNIDQL
LYAIADKLEEYKDVDFTVEEEESVGINRVLYKHTPSQDKFTILRDDDGAYVVSGNAIERMFKMTDFNSDPAVRRFARQMR
SMGIDDALRERGCKNGDIVRILGGEFEFVE
>Mature_430_residues
MFVDQVKISLKAGDGGNGITAYRREKYVPFGGPAGGDGGKGASVVFEVDEGSRTLLDFRYQRHFKASKGENGQSSNMHGK
NAEDLVLKVPPGTIIKNVETDEVLADLVEDGQRAVVAKGGRGGRGNSRFATPRNPAPDFSEKGEPGEELDVSLELKLLAD
VGLVGFPSVGKSTLLSIVSKAKPKIGAYHFTTIKPNLGVVSAPDQRSFVMADLPGLIEGASDGVGLGHQFLRHVERTKVI
VHMIDMSGSEGREPIEDYKVINQELAAYEQRLEDRPQIVVANKMDLPESQDNLILFKEEIGEDVPVIPVSTITRDNIDQL
LYAIADKLEEYKDVDFTVEEEESVGINRVLYKHTPSQDKFTILRDDDGAYVVSGNAIERMFKMTDFNSDPAVRRFARQMR
SMGIDDALRERGCKNGDIVRILGGEFEFVE

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI24308117, Length=337, Percent_Identity=39.1691394658754, Blast_Score=202, Evalue=7e-52,
Organism=Homo sapiens, GI111955139, Length=357, Percent_Identity=34.453781512605, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI111955063, Length=246, Percent_Identity=34.9593495934959, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI4758796, Length=118, Percent_Identity=38.135593220339, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI58761500, Length=135, Percent_Identity=31.1111111111111, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI4557537, Length=92, Percent_Identity=40.2173913043478, Blast_Score=69, Evalue=8e-12,
Organism=Escherichia coli, GI1789574, Length=285, Percent_Identity=48.7719298245614, Blast_Score=258, Evalue=7e-70,
Organism=Escherichia coli, GI1787454, Length=131, Percent_Identity=38.1679389312977, Blast_Score=81, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17508313, Length=324, Percent_Identity=37.6543209876543, Blast_Score=169, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI17552324, Length=303, Percent_Identity=31.023102310231, Blast_Score=142, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI17509631, Length=175, Percent_Identity=30.8571428571429, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17555344, Length=153, Percent_Identity=32.6797385620915, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71981008, Length=118, Percent_Identity=38.135593220339, Blast_Score=73, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6321962, Length=162, Percent_Identity=40.7407407407407, Blast_Score=124, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6319281, Length=126, Percent_Identity=34.9206349206349, Blast_Score=70, Evalue=4e-13,
Organism=Drosophila melanogaster, GI20129375, Length=338, Percent_Identity=40.5325443786982, Blast_Score=199, Evalue=4e-51,
Organism=Drosophila melanogaster, GI24585318, Length=292, Percent_Identity=37.3287671232877, Blast_Score=174, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24640873, Length=142, Percent_Identity=33.0985915492958, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24640877, Length=142, Percent_Identity=33.0985915492958, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24640875, Length=142, Percent_Identity=33.0985915492958, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI17981711, Length=127, Percent_Identity=37.007874015748, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21356473, Length=163, Percent_Identity=34.3558282208589, Blast_Score=74, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014100
- InterPro:   IPR015349
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF09269 DUF1967; PF01018 GTP1_OBG; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 47205; Mature: 47205

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFVDQVKISLKAGDGGNGITAYRREKYVPFGGPAGGDGGKGASVVFEVDEGSRTLLDFRY
CCCCEEEEEEEECCCCCCCCHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHH
QRHFKASKGENGQSSNMHGKNAEDLVLKVPPGTIIKNVETDEVLADLVEDGQRAVVAKGG
HHHHCCCCCCCCCCCCCCCCCCCCEEEECCCCHHCCCCCHHHHHHHHHHCCCEEEEEECC
RGGRGNSRFATPRNPAPDFSEKGEPGEELDVSLELKLLADVGLVGFPSVGKSTLLSIVSK
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCHHHHHHHHHH
AKPKIGAYHFTTIKPNLGVVSAPDQRSFVMADLPGLIEGASDGVGLGHQFLRHVERTKVI
CCCCCCEEEEEEECCCCCEEECCCCCCEEEECCCHHHCCCCCCCCHHHHHHHHHHHHEEE
VHMIDMSGSEGREPIEDYKVINQELAAYEQRLEDRPQIVVANKMDLPESQDNLILFKEEI
EEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCEEEEHHHH
GEDVPVIPVSTITRDNIDQLLYAIADKLEEYKDVDFTVEEEESVGINRVLYKHTPSQDKF
CCCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCEEECCCCCCCEEEEEECCCCCCCE
TILRDDDGAYVVSGNAIERMFKMTDFNSDPAVRRFARQMRSMGIDDALRERGCKNGDIVR
EEEECCCCCEEEECHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHCCCCCCCEEE
ILGGEFEFVE
EECCCEEECC
>Mature Secondary Structure
MFVDQVKISLKAGDGGNGITAYRREKYVPFGGPAGGDGGKGASVVFEVDEGSRTLLDFRY
CCCCEEEEEEEECCCCCCCCHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHH
QRHFKASKGENGQSSNMHGKNAEDLVLKVPPGTIIKNVETDEVLADLVEDGQRAVVAKGG
HHHHCCCCCCCCCCCCCCCCCCCCEEEECCCCHHCCCCCHHHHHHHHHHCCCEEEEEECC
RGGRGNSRFATPRNPAPDFSEKGEPGEELDVSLELKLLADVGLVGFPSVGKSTLLSIVSK
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCHHHHHHHHHH
AKPKIGAYHFTTIKPNLGVVSAPDQRSFVMADLPGLIEGASDGVGLGHQFLRHVERTKVI
CCCCCCEEEEEEECCCCCEEECCCCCCEEEECCCHHHCCCCCCCCHHHHHHHHHHHHEEE
VHMIDMSGSEGREPIEDYKVINQELAAYEQRLEDRPQIVVANKMDLPESQDNLILFKEEI
EEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCEEEEHHHH
GEDVPVIPVSTITRDNIDQLLYAIADKLEEYKDVDFTVEEEESVGINRVLYKHTPSQDKF
CCCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCEEECCCCCCCEEEEEECCCCCCCE
TILRDDDGAYVVSGNAIERMFKMTDFNSDPAVRRFARQMRSMGIDDALRERGCKNGDIVR
EEEECCCCCEEEECHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHCCCCCCCEEE
ILGGEFEFVE
EECCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA