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The map label for this gene is holA

Identifier: 82751190

GI number: 82751190

Start: 1576458

End: 1577432

Strand: Reverse

Name: holA

Synonym: SAB1459c

Alternate gene names: 82751190

Gene position: 1577432-1576458 (Counterclockwise)

Preceding gene: 82751191

Following gene: 82751188

Centisome position: 57.52

GC content: 26.97

Gene sequence:

>975_bases
ATGAGCGACAATATTGTAGCTATTTATGGAGATGTGCCTGAATTGGTTGAAAAACAAAGTGCAGAAATCATATCACAATT
TTTGAAAAGTGATAGAGATGACTTTAACTTTGTGAAATATAATTTATACGAAACAGAGATTGCACCAATTGTTGAAGAAA
CATTAACATTGCCTTTCTTTTCAGATAAAAAAGCAATTTTGGTTAAAAATGCATATATATTTACAGGTGAAAAATCGCCA
AAAGATATGGCTCACAATGTAGATCAATTAATAGAATTTATTGAAAAATATGATGGCGAAAATTTGATTGTCTTTGAGAT
ATATCAAAATAAACTTGATGAAAGAAAAAAGTTAACTAAAACTCTAAAAAAGCATGCAAGGCTTAAAAAAATAGAGCAAA
TGTCTGAAGAAGAAATAAAAAAATGGATTCAAAGTAAATTAAATGAGAATTTCAAAGATATCAAAAGAGATGCATTAGAT
TTATTTATTGAGTTGACAGGTATTAACTTTAATATTGTCTCACAAGAGATAGAAAAGTTGATTTTATTTTTAGGCGATAG
ACCAACAATCAATAAGCAGGATGTTAACCAAATTATTAATAGAAGTTTAGAGCAAAATGTATTTTTACTGACTGAATACA
TTCAGAAAAGAAAGAAAGAACAAGCAATTCATTTAGTAAAAGATTTAATAACTATGAAAGAAGAACCTATTAAATTACTT
GCATTAATTACAAGTAATTACCGATTATTTTATCAATGTAAGATTCTGAGTCAAAAAGGATATAGTGGACAGCAAATTGC
TAAAACAATAGGCGTACATCCATACAGAGTAAAATTAGCGTTAGGACAAGTAAGACATTATCAACTTGATGAATTATTGA
ATATTATAGATGCTTGTGCGGAAACTGATTATAAACTTAAATCATCATATATGGATAAACAGTTAATACTGGAATTATTC
ATTCTATCTTTATAA

Upstream 100 bases:

>100_bases
TAAAAGTTGATTCAAACTCTTATGGAAATGCAAGTGGTTTATAGATACAGAAACATGATATAATCTATTGATGTGTCAAA
CGAATGAAAGGGTGTAATGA

Downstream 100 bases:

>100_bases
AAAATAAAAGTTCAAGCATGCGCTTGAACTTTTATTTAAAAAGATTATTTATTTGCAGTCATTAATTGTGATTTAATACG
GTCAGCTTTGTTTGAATGTA

Product: DNA polymerase III subunit delta

Products: diphosphate; DNAn+1

Alternate protein names: NA

Number of amino acids: Translated: 324; Mature: 323

Protein sequence:

>324_residues
MSDNIVAIYGDVPELVEKQSAEIISQFLKSDRDDFNFVKYNLYETEIAPIVEETLTLPFFSDKKAILVKNAYIFTGEKSP
KDMAHNVDQLIEFIEKYDGENLIVFEIYQNKLDERKKLTKTLKKHARLKKIEQMSEEEIKKWIQSKLNENFKDIKRDALD
LFIELTGINFNIVSQEIEKLILFLGDRPTINKQDVNQIINRSLEQNVFLLTEYIQKRKKEQAIHLVKDLITMKEEPIKLL
ALITSNYRLFYQCKILSQKGYSGQQIAKTIGVHPYRVKLALGQVRHYQLDELLNIIDACAETDYKLKSSYMDKQLILELF
ILSL

Sequences:

>Translated_324_residues
MSDNIVAIYGDVPELVEKQSAEIISQFLKSDRDDFNFVKYNLYETEIAPIVEETLTLPFFSDKKAILVKNAYIFTGEKSP
KDMAHNVDQLIEFIEKYDGENLIVFEIYQNKLDERKKLTKTLKKHARLKKIEQMSEEEIKKWIQSKLNENFKDIKRDALD
LFIELTGINFNIVSQEIEKLILFLGDRPTINKQDVNQIINRSLEQNVFLLTEYIQKRKKEQAIHLVKDLITMKEEPIKLL
ALITSNYRLFYQCKILSQKGYSGQQIAKTIGVHPYRVKLALGQVRHYQLDELLNIIDACAETDYKLKSSYMDKQLILELF
ILSL
>Mature_323_residues
SDNIVAIYGDVPELVEKQSAEIISQFLKSDRDDFNFVKYNLYETEIAPIVEETLTLPFFSDKKAILVKNAYIFTGEKSPK
DMAHNVDQLIEFIEKYDGENLIVFEIYQNKLDERKKLTKTLKKHARLKKIEQMSEEEIKKWIQSKLNENFKDIKRDALDL
FIELTGINFNIVSQEIEKLILFLGDRPTINKQDVNQIINRSLEQNVFLLTEYIQKRKKEQAIHLVKDLITMKEEPIKLLA
LITSNYRLFYQCKILSQKGYSGQQIAKTIGVHPYRVKLALGQVRHYQLDELLNIIDACAETDYKLKSSYMDKQLILELFI
LSL

Specific function: Unknown

COG id: COG1466

COG function: function code L; DNA polymerase III, delta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008921
- InterPro:   IPR010372
- InterPro:   IPR005790 [H]

Pfam domain/function: PF06144 DNA_pol3_delta [H]

EC number: 2.7.7.7

Molecular weight: Translated: 37953; Mature: 37821

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDNIVAIYGDVPELVEKQSAEIISQFLKSDRDDFNFVKYNLYETEIAPIVEETLTLPFF
CCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEHHHHHHHHHHHHCCCCC
SDKKAILVKNAYIFTGEKSPKDMAHNVDQLIEFIEKYDGENLIVFEIYQNKLDERKKLTK
CCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHH
TLKKHARLKKIEQMSEEEIKKWIQSKLNENFKDIKRDALDLFIELTGINFNIVSQEIEKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHEECCCHHHHHHHHHHH
ILFLGDRPTINKQDVNQIINRSLEQNVFLLTEYIQKRKKEQAIHLVKDLITMKEEPIKLL
HHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
ALITSNYRLFYQCKILSQKGYSGQQIAKTIGVHPYRVKLALGQVRHYQLDELLNIIDACA
HHHHCCCEEEEEEEEECCCCCCHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHH
ETDYKLKSSYMDKQLILELFILSL
CCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SDNIVAIYGDVPELVEKQSAEIISQFLKSDRDDFNFVKYNLYETEIAPIVEETLTLPFF
CCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEHHHHHHHHHHHHCCCCC
SDKKAILVKNAYIFTGEKSPKDMAHNVDQLIEFIEKYDGENLIVFEIYQNKLDERKKLTK
CCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHH
TLKKHARLKKIEQMSEEEIKKWIQSKLNENFKDIKRDALDLFIELTGINFNIVSQEIEKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHEECCCHHHHHHHHHHH
ILFLGDRPTINKQDVNQIINRSLEQNVFLLTEYIQKRKKEQAIHLVKDLITMKEEPIKLL
HHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
ALITSNYRLFYQCKILSQKGYSGQQIAKTIGVHPYRVKLALGQVRHYQLDELLNIIDACA
HHHHCCCEEEEEEEEECCCCCCHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHH
ETDYKLKSSYMDKQLILELFILSL
CCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: deoxynucleoside triphosphate; DNAn

Specific reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]