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The map label for this gene is dapA

Identifier: 82750986

GI number: 82750986

Start: 1366529

End: 1367416

Strand: Direct

Name: dapA

Synonym: SAB1250

Alternate gene names: 82750986

Gene position: 1366529-1367416 (Clockwise)

Preceding gene: 82750985

Following gene: 82750987

Centisome position: 49.83

GC content: 34.91

Gene sequence:

>888_bases
ATGACACATTTATTTGAGGGTGTTGGCGTTGCACTTACAACCCCTTTTACAAATAACAAAGTTAATCTTGAAGCTTTGAA
AGCACACGTTAATTTTTTACTAGAAAATAATGCCCAAGCAATCATCGTTAATGGAACTACTGCTGAGAGCCCTACTTTAA
CAACAGATGAAAAAGAACTCATTCTAAAAACAGTTATTGATCTTGTAGATAAACGTGTTCCTGTCATAGCAGGAACTGGA
ACTAATGATACTGAAAAGTCAATCCAAGCTTCAATCCAAGCTAAAGCCTTAGGGGCTGATGCAATTATGTTAATTACGAC
CTACTACAACAAAACGAATCAACGTGGTTTAGTAAAACATTTTGAAGCGATTGCAGATGCTGTGAAATTACCAGTCGTGC
TGTACAATGTTCCTTCAAGAACGAACATGACAATTGAACCAGAAACTGTAGAAATATTAAGTCAACATCCTTCAATTGTA
GCTTTAAAAGATGCTACGAATGATTTTGAGTATTTAGAAGAAGTGAAAAAGCGAATTGATACAAATTCATTTGCATTATA
TAGTGGCAATGATGACAACGTCGTCGAATACTATCAACGTGGCGGTAAAGGCGTTATTTCTGTCATTGCTAATGTAATTC
CTAAAGAATTTCAAGCGTTATACGATGCTCAACAAAGCGGATTAGATATTCAAGATCAATTTAAACCAATCGGCATACTG
TTGTCAGCCCTATCAGTTGATATTAACCCAATTCCTATTAAAGCTTTAACAAGTTATTTAGGATTTGGAAACTATGAATT
ACGTCTGCCATTAATTACACTAGAAGATACAGATACTAAAGTGCTTCGTGAAGCATATAACATATTTAAAGCGGGTGAAA
ATGAGTGA

Upstream 100 bases:

>100_bases
TTCCATGTATGGTGTACAGCAGACAATTTATTAAAAGGTGCTGCATTAAATGCTGTACAAGTATTGGAACAAGTTATGCG
TTTAAAAGGAGCGAATTAAA

Downstream 100 bases:

>100_bases
AAATATTACTAATTGGCTATGGCGCAATGAATCAACGCGTTGCTAGATTAGCAGAAGAAAAAGGCCATGAAATTGTGGGG
GTAATCGAACCTACACCGAG

Product: dihydrodipicolinate synthase

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 295; Mature: 294

Protein sequence:

>295_residues
MTHLFEGVGVALTTPFTNNKVNLEALKAHVNFLLENNAQAIIVNGTTAESPTLTTDEKELILKTVIDLVDKRVPVIAGTG
TNDTEKSIQASIQAKALGADAIMLITTYYNKTNQRGLVKHFEAIADAVKLPVVLYNVPSRTNMTIEPETVEILSQHPSIV
ALKDATNDFEYLEEVKKRIDTNSFALYSGNDDNVVEYYQRGGKGVISVIANVIPKEFQALYDAQQSGLDIQDQFKPIGIL
LSALSVDINPIPIKALTSYLGFGNYELRLPLITLEDTDTKVLREAYNIFKAGENE

Sequences:

>Translated_295_residues
MTHLFEGVGVALTTPFTNNKVNLEALKAHVNFLLENNAQAIIVNGTTAESPTLTTDEKELILKTVIDLVDKRVPVIAGTG
TNDTEKSIQASIQAKALGADAIMLITTYYNKTNQRGLVKHFEAIADAVKLPVVLYNVPSRTNMTIEPETVEILSQHPSIV
ALKDATNDFEYLEEVKKRIDTNSFALYSGNDDNVVEYYQRGGKGVISVIANVIPKEFQALYDAQQSGLDIQDQFKPIGIL
LSALSVDINPIPIKALTSYLGFGNYELRLPLITLEDTDTKVLREAYNIFKAGENE
>Mature_294_residues
THLFEGVGVALTTPFTNNKVNLEALKAHVNFLLENNAQAIIVNGTTAESPTLTTDEKELILKTVIDLVDKRVPVIAGTGT
NDTEKSIQASIQAKALGADAIMLITTYYNKTNQRGLVKHFEAIADAVKLPVVLYNVPSRTNMTIEPETVEILSQHPSIVA
LKDATNDFEYLEEVKKRIDTNSFALYSGNDDNVVEYYQRGGKGVISVIANVIPKEFQALYDAQQSGLDIQDQFKPIGILL
SALSVDINPIPIKALTSYLGFGNYELRLPLITLEDTDTKVLREAYNIFKAGENE

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; first step. [C]

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=283, Percent_Identity=26.1484098939929, Blast_Score=110, Evalue=2e-24,
Organism=Escherichia coli, GI1788823, Length=291, Percent_Identity=35.7388316151203, Blast_Score=173, Evalue=1e-44,
Organism=Escherichia coli, GI1786463, Length=228, Percent_Identity=31.140350877193, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI87082415, Length=227, Percent_Identity=29.9559471365639, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI1789620, Length=229, Percent_Identity=27.0742358078603, Blast_Score=95, Evalue=5e-21,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 32460; Mature: 32329

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: PS00666 DHDPS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHLFEGVGVALTTPFTNNKVNLEALKAHVNFLLENNAQAIIVNGTTAESPTLTTDEKEL
CCCCCCCCCEEEECCCCCCEEHHHHHHHHHHHEEECCCCEEEEECCCCCCCCCCCCHHHH
ILKTVIDLVDKRVPVIAGTGTNDTEKSIQASIQAKALGADAIMLITTYYNKTNQRGLVKH
HHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCHHHHH
FEAIADAVKLPVVLYNVPSRTNMTIEPETVEILSQHPSIVALKDATNDFEYLEEVKKRID
HHHHHHHHHCCEEEEECCCCCCEEECCHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCC
TNSFALYSGNDDNVVEYYQRGGKGVISVIANVIPKEFQALYDAQQSGLDIQDQFKPIGIL
CCCEEEEECCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
LSALSVDINPIPIKALTSYLGFGNYELRLPLITLEDTDTKVLREAYNIFKAGENE
HHHHHCCCCCCCHHHHHHHHCCCCEEEEEEEEEECCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
THLFEGVGVALTTPFTNNKVNLEALKAHVNFLLENNAQAIIVNGTTAESPTLTTDEKEL
CCCCCCCCEEEECCCCCCEEHHHHHHHHHHHEEECCCCEEEEECCCCCCCCCCCCHHHH
ILKTVIDLVDKRVPVIAGTGTNDTEKSIQASIQAKALGADAIMLITTYYNKTNQRGLVKH
HHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCHHHHH
FEAIADAVKLPVVLYNVPSRTNMTIEPETVEILSQHPSIVALKDATNDFEYLEEVKKRID
HHHHHHHHHCCEEEEECCCCCCEEECCHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCC
TNSFALYSGNDDNVVEYYQRGGKGVISVIANVIPKEFQALYDAQQSGLDIQDQFKPIGIL
CCCEEEEECCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
LSALSVDINPIPIKALTSYLGFGNYELRLPLITLEDTDTKVLREAYNIFKAGENE
HHHHHCCCCCCCHHHHHHHHCCCCEEEEEEEEEECCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA