Click here to switch to the map view.

The map label for this gene is tkt [H]

Identifier: 82750936

GI number: 82750936

Start: 1304621

End: 1306609

Strand: Direct

Name: tkt [H]

Synonym: SAB1200

Alternate gene names: 82750936

Gene position: 1304621-1306609 (Clockwise)

Preceding gene: 82750935

Following gene: 82750937

Centisome position: 47.57

GC content: 36.3

Gene sequence:

>1989_bases
ATGTTTAATGAAAAAGATCAATTAGCTGTTGATACGCTACGTGCACTAAGTATCGACACAATCGAAAAAGCGAATTCTGG
TCATCCAGGATTACCTATGGGAGCTGCCCCAATGGCTTACACTTTGTGGACACGTCATCTGAATTTTAATCCACAATCTA
AAGATTACTTCAATAGAGACCGTTTCGTATTATCAGCAGGGCATGGTTCAGCACTATTGTATAGCTTGTTACATGTTTCT
GGTAGTTTAGAATTAGAAGAATTAAAGCAATTTAGACAATGGGGTTCTAAAACACCAGGTCATCCTGAATACAGACATAC
AGATGGTGTAGAAGTTACTACTGGACCACTTGGACAAGGTTTTGCTATGTCAGTAGGATTAGCTTTAGCAGAACGTCACC
TAGCAGGGAAATTTAATAAAGAAGGATATAATGTTGTAGATCATTACACATATGTATTAGCTTCTGACGGTGATTTAATG
GAAGGTATTTCGCATGAAGCAGCTTCATTTGCTGGACATAATAAATTAAGTAAATTAGTTGTTTTATACGATTCAAATGA
TATTTCATTAGATGGCGAATTAAACAAAGCTTTTTCTGAAAACACAAAAGCTCGTTTTGAAGCATATGGTTGGAATTACT
TACTAGTTAAAGATGGTAATGATTTAGAAGAAATTGATAATGCGATTACTACTGCTAAATCTCAAGAAGGACCAACAATT
ATCGAAGTTAAAACAACAATCGGATTTGGTTCACCGAATAAAGCAGGAACTAATGGTGTTCATGGGGCACCTTTAGGTGA
AGATGAAAGAAAATTAACATTCGAAAATTACGGTTTAGATCCTGAAAAACGTTTTAATGTTTCAGAAGAAGTATACGAAA
TTTTCCAAAATACTATGTTAAAACGTGCTAATGAAGATGAATCTCAATGGAATTCATTATTAGAAAAATATGCAGAAACA
TATCCTGAATTAGCAGAAGAATTTAAATTAGCGATTAGTGGTAAATTGCCTAAAAATTATAAGGATGAATTACCACGTTT
TGAACTTGGTCATAATGGTGCATCTCGTGCTGATTCTGGTACTGTTATTCAAGCAATCAGTAAAACTGTCCCTTCATTCT
TTGGTGGATCAGCAGACCTTGCTGGTTCAAACAAATCCAATGTAAATGATGCAACTGATTATAGTTCTGAAACACCTGAA
GGTAAAAATGTGTGGTTTGGTGTACGTGAATTTGCTATGGGTGCTGCTGTAAATGGTATGGCTGCACATGGAGGTTTACA
TCCATATGGTGCAACATTCTTCGTATTTAGTGATTATTTAAAACCAGCGTTACGCTTATCATCAATTATGGGATTAAATG
CTACGTTCATCTTCACACATGATTCAATTGCAGTAGGTGAAGATGGTCCTACTCATGAACCAATTGAACAATTAGCTGGA
CTAAGAGCCATTCCAAATATGAATGTTATCCGTCCTGCAGATGGTAATGAAACAAGAGTAGCATGGGAAGTCGCCTTAGA
ATCTGAATCTACACCTACTTCATTAGTATTGACACGCCAAAACTTACCGGTTTTAGATGTACCAGAAGATGTAGTTGAAG
AAGGCGTTCGAAAAGGTGCCTATACAGTTTATGGCTCTGAAGAGACACCAGAATTCCTATTATTAGCTTCAGGTTCAGAA
GTTAGTCTTGCAGTTGAAGCTGCTAAAGATCTTGAAAAGCAAGGTAAATCAGTGCGTGTTGTTTCAATGCCTAACTGGAA
TGCATTTGAACAACAATCTGAAGAATATAAAGAATCAGTTATTCCATCAAGCGTAACAAAACGTGTTGCGATTGAAATGG
CTTCACCGCTAGGATGGCATAAATATGTAGGTACTGCAGGTGAAGTTATTGCTATTGACGGCTTTGGCGCAAGTGCACCT
GGCGATTTAGTAGTTGAAAAATATGGCTTTACAAAAGAAAATATCTTAAACCAAGTTATGTGCTTATAA

Upstream 100 bases:

>100_bases
TTTCTGACATTACAACTTGAAATAAGTATTTTACTTATCTTTTTATTTTAAAATAAGTTATAATGTATTTGATAAAGTTG
AAGAAGGGAAGATACACAAG

Downstream 100 bases:

>100_bases
GAATAATTTATAAAGCGAGTATGTTTAGAAGTCTAGGATGCATAATCTTAGGCTTCTTTTAAAGTGGTGAAATTTAGAGT
ATAGCACTCAAACTACATCA

Product: transketolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 662; Mature: 662

Protein sequence:

>662_residues
MFNEKDQLAVDTLRALSIDTIEKANSGHPGLPMGAAPMAYTLWTRHLNFNPQSKDYFNRDRFVLSAGHGSALLYSLLHVS
GSLELEELKQFRQWGSKTPGHPEYRHTDGVEVTTGPLGQGFAMSVGLALAERHLAGKFNKEGYNVVDHYTYVLASDGDLM
EGISHEAASFAGHNKLSKLVVLYDSNDISLDGELNKAFSENTKARFEAYGWNYLLVKDGNDLEEIDNAITTAKSQEGPTI
IEVKTTIGFGSPNKAGTNGVHGAPLGEDERKLTFENYGLDPEKRFNVSEEVYEIFQNTMLKRANEDESQWNSLLEKYAET
YPELAEEFKLAISGKLPKNYKDELPRFELGHNGASRADSGTVIQAISKTVPSFFGGSADLAGSNKSNVNDATDYSSETPE
GKNVWFGVREFAMGAAVNGMAAHGGLHPYGATFFVFSDYLKPALRLSSIMGLNATFIFTHDSIAVGEDGPTHEPIEQLAG
LRAIPNMNVIRPADGNETRVAWEVALESESTPTSLVLTRQNLPVLDVPEDVVEEGVRKGAYTVYGSEETPEFLLLASGSE
VSLAVEAAKDLEKQGKSVRVVSMPNWNAFEQQSEEYKESVIPSSVTKRVAIEMASPLGWHKYVGTAGEVIAIDGFGASAP
GDLVVEKYGFTKENILNQVMCL

Sequences:

>Translated_662_residues
MFNEKDQLAVDTLRALSIDTIEKANSGHPGLPMGAAPMAYTLWTRHLNFNPQSKDYFNRDRFVLSAGHGSALLYSLLHVS
GSLELEELKQFRQWGSKTPGHPEYRHTDGVEVTTGPLGQGFAMSVGLALAERHLAGKFNKEGYNVVDHYTYVLASDGDLM
EGISHEAASFAGHNKLSKLVVLYDSNDISLDGELNKAFSENTKARFEAYGWNYLLVKDGNDLEEIDNAITTAKSQEGPTI
IEVKTTIGFGSPNKAGTNGVHGAPLGEDERKLTFENYGLDPEKRFNVSEEVYEIFQNTMLKRANEDESQWNSLLEKYAET
YPELAEEFKLAISGKLPKNYKDELPRFELGHNGASRADSGTVIQAISKTVPSFFGGSADLAGSNKSNVNDATDYSSETPE
GKNVWFGVREFAMGAAVNGMAAHGGLHPYGATFFVFSDYLKPALRLSSIMGLNATFIFTHDSIAVGEDGPTHEPIEQLAG
LRAIPNMNVIRPADGNETRVAWEVALESESTPTSLVLTRQNLPVLDVPEDVVEEGVRKGAYTVYGSEETPEFLLLASGSE
VSLAVEAAKDLEKQGKSVRVVSMPNWNAFEQQSEEYKESVIPSSVTKRVAIEMASPLGWHKYVGTAGEVIAIDGFGASAP
GDLVVEKYGFTKENILNQVMCL
>Mature_662_residues
MFNEKDQLAVDTLRALSIDTIEKANSGHPGLPMGAAPMAYTLWTRHLNFNPQSKDYFNRDRFVLSAGHGSALLYSLLHVS
GSLELEELKQFRQWGSKTPGHPEYRHTDGVEVTTGPLGQGFAMSVGLALAERHLAGKFNKEGYNVVDHYTYVLASDGDLM
EGISHEAASFAGHNKLSKLVVLYDSNDISLDGELNKAFSENTKARFEAYGWNYLLVKDGNDLEEIDNAITTAKSQEGPTI
IEVKTTIGFGSPNKAGTNGVHGAPLGEDERKLTFENYGLDPEKRFNVSEEVYEIFQNTMLKRANEDESQWNSLLEKYAET
YPELAEEFKLAISGKLPKNYKDELPRFELGHNGASRADSGTVIQAISKTVPSFFGGSADLAGSNKSNVNDATDYSSETPE
GKNVWFGVREFAMGAAVNGMAAHGGLHPYGATFFVFSDYLKPALRLSSIMGLNATFIFTHDSIAVGEDGPTHEPIEQLAG
LRAIPNMNVIRPADGNETRVAWEVALESESTPTSLVLTRQNLPVLDVPEDVVEEGVRKGAYTVYGSEETPEFLLLASGSE
VSLAVEAAKDLEKQGKSVRVVSMPNWNAFEQQSEEYKESVIPSSVTKRVAIEMASPLGWHKYVGTAGEVIAIDGFGASAP
GDLVVEKYGFTKENILNQVMCL

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=590, Percent_Identity=27.1186440677966, Blast_Score=162, Evalue=8e-40,
Organism=Homo sapiens, GI4507521, Length=590, Percent_Identity=27.1186440677966, Blast_Score=162, Evalue=8e-40,
Organism=Homo sapiens, GI133778974, Length=578, Percent_Identity=25.9515570934256, Blast_Score=139, Evalue=1e-32,
Organism=Homo sapiens, GI225637461, Length=597, Percent_Identity=22.1105527638191, Blast_Score=110, Evalue=4e-24,
Organism=Homo sapiens, GI225637463, Length=597, Percent_Identity=22.1105527638191, Blast_Score=110, Evalue=4e-24,
Organism=Homo sapiens, GI225637459, Length=597, Percent_Identity=22.1105527638191, Blast_Score=110, Evalue=5e-24,
Organism=Escherichia coli, GI48994911, Length=662, Percent_Identity=45.4682779456193, Blast_Score=582, Evalue=1e-167,
Organism=Escherichia coli, GI1788808, Length=653, Percent_Identity=45.9418070444104, Blast_Score=579, Evalue=1e-166,
Organism=Caenorhabditis elegans, GI17539652, Length=575, Percent_Identity=27.304347826087, Blast_Score=166, Evalue=5e-41,
Organism=Saccharomyces cerevisiae, GI6325331, Length=664, Percent_Identity=46.5361445783133, Blast_Score=575, Evalue=1e-165,
Organism=Saccharomyces cerevisiae, GI6319593, Length=668, Percent_Identity=42.9640718562874, Blast_Score=537, Evalue=1e-153,
Organism=Drosophila melanogaster, GI45551847, Length=576, Percent_Identity=27.2569444444444, Blast_Score=169, Evalue=6e-42,
Organism=Drosophila melanogaster, GI45550715, Length=576, Percent_Identity=27.2569444444444, Blast_Score=169, Evalue=6e-42,
Organism=Drosophila melanogaster, GI24666278, Length=578, Percent_Identity=27.5086505190311, Blast_Score=168, Evalue=1e-41,
Organism=Drosophila melanogaster, GI24645119, Length=548, Percent_Identity=27.007299270073, Blast_Score=156, Evalue=5e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005478
- InterPro:   IPR020826
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C; PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 72311; Mature: 72311

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS00801 TRANSKETOLASE_1 ; PS00802 TRANSKETOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNEKDQLAVDTLRALSIDTIEKANSGHPGLPMGAAPMAYTLWTRHLNFNPQSKDYFNRD
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEHHHCCCCCCCCCCCCCCC
RFVLSAGHGSALLYSLLHVSGSLELEELKQFRQWGSKTPGHPEYRHTDGVEVTTGPLGQG
CEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCC
FAMSVGLALAERHLAGKFNKEGYNVVDHYTYVLASDGDLMEGISHEAASFAGHNKLSKLV
HHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHCCCCCEEEE
VLYDSNDISLDGELNKAFSENTKARFEAYGWNYLLVKDGNDLEEIDNAITTAKSQEGPTI
EEECCCCEEECCCHHHHHHCCCCCEEEEECCEEEEEECCCCHHHHHHHHHHCCCCCCCEE
IEVKTTIGFGSPNKAGTNGVHGAPLGEDERKLTFENYGLDPEKRFNVSEEVYEIFQNTML
EEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEHHHCCCCHHHHCCCHHHHHHHHHHHHH
KRANEDESQWNSLLEKYAETYPELAEEFKLAISGKLPKNYKDELPRFELGHNGASRADSG
HHCCCCHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHCCCCEEECCCCCCCCCCC
TVIQAISKTVPSFFGGSADLAGSNKSNVNDATDYSSETPEGKNVWFGVREFAMGAAVNGM
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHCCCH
AAHGGLHPYGATFFVFSDYLKPALRLSSIMGLNATFIFTHDSIAVGEDGPTHEPIEQLAG
HHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCEEECCCCCCHHHHHHHHC
LRAIPNMNVIRPADGNETRVAWEVALESESTPTSLVLTRQNLPVLDVPEDVVEEGVRKGA
CCCCCCCCEEECCCCCCCEEEEEEEECCCCCCCEEEEEECCCCEECCCHHHHHHHHHCCC
YTVYGSEETPEFLLLASGSEVSLAVEAAKDLEKQGKSVRVVSMPNWNAFEQQSEEYKESV
EEEECCCCCCCEEEEECCCCEEEEHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHC
IPSSVTKRVAIEMASPLGWHKYVGTAGEVIAIDGFGASAPGDLVVEKYGFTKENILNQVM
CCHHHHHHHHHHHCCCCCHHHHHCCCCCEEEEECCCCCCCCCEEEEECCCCHHHHHHHHH
CL
CC
>Mature Secondary Structure
MFNEKDQLAVDTLRALSIDTIEKANSGHPGLPMGAAPMAYTLWTRHLNFNPQSKDYFNRD
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEHHHCCCCCCCCCCCCCCC
RFVLSAGHGSALLYSLLHVSGSLELEELKQFRQWGSKTPGHPEYRHTDGVEVTTGPLGQG
CEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCC
FAMSVGLALAERHLAGKFNKEGYNVVDHYTYVLASDGDLMEGISHEAASFAGHNKLSKLV
HHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHCCCCCEEEE
VLYDSNDISLDGELNKAFSENTKARFEAYGWNYLLVKDGNDLEEIDNAITTAKSQEGPTI
EEECCCCEEECCCHHHHHHCCCCCEEEEECCEEEEEECCCCHHHHHHHHHHCCCCCCCEE
IEVKTTIGFGSPNKAGTNGVHGAPLGEDERKLTFENYGLDPEKRFNVSEEVYEIFQNTML
EEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEHHHCCCCHHHHCCCHHHHHHHHHHHHH
KRANEDESQWNSLLEKYAETYPELAEEFKLAISGKLPKNYKDELPRFELGHNGASRADSG
HHCCCCHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHCCCCEEECCCCCCCCCCC
TVIQAISKTVPSFFGGSADLAGSNKSNVNDATDYSSETPEGKNVWFGVREFAMGAAVNGM
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHCCCH
AAHGGLHPYGATFFVFSDYLKPALRLSSIMGLNATFIFTHDSIAVGEDGPTHEPIEQLAG
HHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCEEECCCCCCHHHHHHHHC
LRAIPNMNVIRPADGNETRVAWEVALESESTPTSLVLTRQNLPVLDVPEDVVEEGVRKGA
CCCCCCCCEEECCCCCCCEEEEEEEECCCCCCCEEEEEECCCCEECCCHHHHHHHHHCCC
YTVYGSEETPEFLLLASGSEVSLAVEAAKDLEKQGKSVRVVSMPNWNAFEQQSEEYKESV
EEEECCCCCCCEEEEECCCCEEEEHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHC
IPSSVTKRVAIEMASPLGWHKYVGTAGEVIAIDGFGASAPGDLVVEKYGFTKENILNQVM
CCHHHHHHHHHHHCCCCCHHHHHCCCCCEEEEECCCCCCCCCEEEEECCCCHHHHHHHHH
CL
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA