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The map label for this gene is bsaA [H]

Identifier: 82750905

GI number: 82750905

Start: 1270237

End: 1270713

Strand: Reverse

Name: bsaA [H]

Synonym: SAB1168c

Alternate gene names: 82750905

Gene position: 1270713-1270237 (Counterclockwise)

Preceding gene: 82750912

Following gene: 82750904

Centisome position: 46.33

GC content: 33.54

Gene sequence:

>477_bases
ATGGAGACAATTTATGATTTTGTAGTAGAAACAAATAAAGGTGTTACTTACAAATTAGATGAATATAAGGGTGACGTTAT
GCTAATTGTCAATACAGCTAGCGAATGTGGCTTTACTTCACAATTTGAAGGTTTGCAATCATTATACGAGAAATACAAAG
ATCAAGGGTTTGTAATTCTAGGTTTCCCTTGTAATCAATTTGGTGGCCAAGAACCTGGATCAGGCGAAGAAGCAGCTCAA
AACTGTAAATTAAACTATGGTGTTACCTTCCCTATGCATCAAAAAATAGACGTAAAAGGGGAACATCAATTACCTTTATT
TAGATATTTGACTGCGGCACAACACGGATTCTTAAATGAGAAAATCAAATGGAATTTCACTAAGTTTTTAGTGGATCGTG
AAGGTAACGTTGTTAAACGATTTGCACCTCAAAAAAAACCTGTTCAAATCGAAAGAGAAATAGAAAAGTTATTATAA

Upstream 100 bases:

>100_bases
CCTTAATAAAATCCTACTCAAAGTATTCTATCATAGAGTTTTAGTAAAGACTATTACACGATTTTATGGTACATTTTAAG
TAAATCGAAAGGATGATTCA

Downstream 100 bases:

>100_bases
AATATACTAGCTCATAGCAAATAAAACGCTTCATATAAAGTCGTATCATATATTGACCCGGCCTTTACGGTTCTATAATA
AATCGGACTGATAGAAAAAG

Product: glutathione peroxidase

Products: glutathione disulfide; H2O

Alternate protein names: NA

Number of amino acids: Translated: 158; Mature: 158

Protein sequence:

>158_residues
METIYDFVVETNKGVTYKLDEYKGDVMLIVNTASECGFTSQFEGLQSLYEKYKDQGFVILGFPCNQFGGQEPGSGEEAAQ
NCKLNYGVTFPMHQKIDVKGEHQLPLFRYLTAAQHGFLNEKIKWNFTKFLVDREGNVVKRFAPQKKPVQIEREIEKLL

Sequences:

>Translated_158_residues
METIYDFVVETNKGVTYKLDEYKGDVMLIVNTASECGFTSQFEGLQSLYEKYKDQGFVILGFPCNQFGGQEPGSGEEAAQ
NCKLNYGVTFPMHQKIDVKGEHQLPLFRYLTAAQHGFLNEKIKWNFTKFLVDREGNVVKRFAPQKKPVQIEREIEKLL
>Mature_158_residues
METIYDFVVETNKGVTYKLDEYKGDVMLIVNTASECGFTSQFEGLQSLYEKYKDQGFVILGFPCNQFGGQEPGSGEEAAQ
NCKLNYGVTFPMHQKIDVKGEHQLPLFRYLTAAQHGFLNEKIKWNFTKFLVDREGNVVKRFAPQKKPVQIEREIEKLL

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI75709200, Length=156, Percent_Identity=40.3846153846154, Blast_Score=119, Evalue=9e-28,
Organism=Homo sapiens, GI90903240, Length=156, Percent_Identity=40.3846153846154, Blast_Score=118, Evalue=2e-27,
Organism=Homo sapiens, GI192455698, Length=153, Percent_Identity=39.8692810457516, Blast_Score=118, Evalue=2e-27,
Organism=Homo sapiens, GI15618997, Length=158, Percent_Identity=38.6075949367089, Blast_Score=112, Evalue=2e-25,
Organism=Homo sapiens, GI90903238, Length=131, Percent_Identity=39.6946564885496, Blast_Score=92, Evalue=2e-19,
Organism=Homo sapiens, GI4557629, Length=173, Percent_Identity=32.9479768786127, Blast_Score=91, Evalue=6e-19,
Organism=Homo sapiens, GI6006001, Length=173, Percent_Identity=32.9479768786127, Blast_Score=77, Evalue=5e-15,
Organism=Homo sapiens, GI33186887, Length=177, Percent_Identity=31.0734463276836, Blast_Score=76, Evalue=1e-14,
Organism=Homo sapiens, GI32967607, Length=182, Percent_Identity=29.6703296703297, Blast_Score=75, Evalue=2e-14,
Organism=Homo sapiens, GI41406084, Length=183, Percent_Identity=29.5081967213115, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1788003, Length=166, Percent_Identity=42.7710843373494, Blast_Score=137, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17506887, Length=159, Percent_Identity=42.7672955974843, Blast_Score=141, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17535473, Length=159, Percent_Identity=41.5094339622642, Blast_Score=136, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI193210707, Length=163, Percent_Identity=46.6257668711656, Blast_Score=126, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI71993584, Length=157, Percent_Identity=36.9426751592357, Blast_Score=115, Evalue=8e-27,
Organism=Caenorhabditis elegans, GI193209493, Length=164, Percent_Identity=36.5853658536585, Blast_Score=102, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI17550320, Length=164, Percent_Identity=35.3658536585366, Blast_Score=98, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71999642, Length=76, Percent_Identity=43.421052631579, Blast_Score=75, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI193210709, Length=72, Percent_Identity=51.3888888888889, Blast_Score=73, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6319721, Length=157, Percent_Identity=54.140127388535, Blast_Score=178, Evalue=4e-46,
Organism=Saccharomyces cerevisiae, GI6322228, Length=159, Percent_Identity=51.5723270440252, Blast_Score=173, Evalue=1e-44,
Organism=Saccharomyces cerevisiae, GI6322826, Length=159, Percent_Identity=44.0251572327044, Blast_Score=134, Evalue=6e-33,
Organism=Drosophila melanogaster, GI24656772, Length=161, Percent_Identity=47.2049689440994, Blast_Score=148, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24656777, Length=161, Percent_Identity=47.2049689440994, Blast_Score=147, Evalue=3e-36,
Organism=Drosophila melanogaster, GI24656767, Length=161, Percent_Identity=47.2049689440994, Blast_Score=147, Evalue=3e-36,
Organism=Drosophila melanogaster, GI85726443, Length=158, Percent_Identity=46.8354430379747, Blast_Score=135, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: 1.11.1.9

Molecular weight: Translated: 18142; Mature: 18142

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS00763 GLUTATHIONE_PEROXID_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METIYDFVVETNKGVTYKLDEYKGDVMLIVNTASECGFTSQFEGLQSLYEKYKDQGFVIL
CCCCEEEEEECCCCCEEEECCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEE
GFPCNQFGGQEPGSGEEAAQNCKLNYGVTFPMHQKIDVKGEHQLPLFRYLTAAQHGFLNE
CCCHHHCCCCCCCCCHHHHHCCEEECCCCCCCCCEECCCCCCCCHHHHHHHHHHCCCCCC
KIKWNFTKFLVDREGNVVKRFAPQKKPVQIEREIEKLL
CEEECEEEEEEECCCCEEECCCCCCCCCHHHHHHHHCC
>Mature Secondary Structure
METIYDFVVETNKGVTYKLDEYKGDVMLIVNTASECGFTSQFEGLQSLYEKYKDQGFVIL
CCCCEEEEEECCCCCEEEECCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEE
GFPCNQFGGQEPGSGEEAAQNCKLNYGVTFPMHQKIDVKGEHQLPLFRYLTAAQHGFLNE
CCCHHHCCCCCCCCCHHHHHCCEEECCCCCCCCCEECCCCCCCCHHHHHHHHHHCCCCCC
KIKWNFTKFLVDREGNVVKRFAPQKKPVQIEREIEKLL
CEEECEEEEEEECCCCEEECCCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: glutathione; H2O2

Specific reaction: 2 glutathione + H2O2 = glutathione disulfide + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA