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The map label for this gene is sucC

Identifier: 82750848

GI number: 82750848

Start: 1198749

End: 1199915

Strand: Direct

Name: sucC

Synonym: SAB1109

Alternate gene names: 82750848

Gene position: 1198749-1199915 (Clockwise)

Preceding gene: 82750847

Following gene: 82750849

Centisome position: 43.71

GC content: 35.3

Gene sequence:

>1167_bases
ATGAATATCCACGAGTATCAAGGTAAAGAAATATTTCGTTCAATGGGCGTTGCAGTTCCAGAAGGACGAGTAGCATTTAC
TGCTGAAGAAGCGGTGGAGAAAGCAAAAGAATTTAATTCTGATGTATATGTTGTAAAAGCACAAATTCATGCTGGAGGTA
GAGGTAAAGCAGGCGGAGTAAAAATTGCTAAATCTTTATCTGAGGTAGAAACATATGCAAAAGAATTATTAGGGAAAACT
TTGGTGACACATCAAACTGGTCCAGAAGGTAAAGAAATTAAGCGTTTATATATTGAAGAAGGTTGTGCTATTCAAAAAGA
ATATTACGTTGGATTCGTTATTGATCGTGCGACTGACCAAGTAACATTGATGGCGTCTGAAGAAGGGGGCACTGAGATTG
AAGAAGTTGCTGCGAAGACTCCTGAAAAGATCTTCAAAGAAACTATCGATCCAGTAATCGGACTTTCACCATTCCAAGCA
AGACGAATTGCGTTTAATATTAATATTCCTAAAGAATCTGTTAACAAAGCTGCTAAATTCTTATTAGCACTTTATAATGT
ATTCATTGAAAAAGATTGTTCAATCGTAGAAATCAACCCATTAGTTACAACAGCTGATGGTGATGTATTGGTATTAGATG
CTAAAATTAATTTTGATGATAATGCATTATTCAGACATAAAGATGTTGTAGAATTACGTGATTTAGAAGAAGAAGATCCG
AAAGAGATTGAAGCGTCTAAACATGATTTATCATACATTGCATTAGATGGTGACATCGGATGTATGGTGAATGGTGCAGG
TTTAGCCATGGCAACAATGGATACAATTAATCATTTCGGTGGAAACCCAGCCAATTTCTTAGATGCAGGCGGAAGCGCTA
CTAGAGAAAAAGTAACTGAAGCATTTAAAATCATTTTAGGTGATGAAAATGTTAAAGGTATTTTTGTAAACATTTTCGGT
GGCATTATGAAATGTGATGTTATCGCAGAAGGTATCGTTGAAGCTGTAAAAGAAGTAGATTTAACTTTACCACTAGTTGT
ACGCTTAGAAGGTACAAATGTTGAGTTAGGTAAAAAAATCTTAAAAGACTCAGGATTAGCAATTGAACCAGCAGCAACAA
TGGCTGAAGGTGCACAAAAAATTGTTAAACTAGTCAAAGAAGCATAA

Upstream 100 bases:

>100_bases
ATTCAATTAAATGATAAAAAAGTAGCATTTAAGTTTACAATAGCGCTTACATTTTTTATAATTGTAAGGGAACTTAACCT
AAGTAACAGGAGGATGGAAG

Downstream 100 bases:

>100_bases
GGAAAGGATGGGAGCACTAAGATGAGTGTATTTATAGATAAGAATACTAAAGTAATGGTACAAGGTATTACAGGGTCTAC
TGCCCTTTTCCATACAAAAC

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MNIHEYQGKEIFRSMGVAVPEGRVAFTAEEAVEKAKEFNSDVYVVKAQIHAGGRGKAGGVKIAKSLSEVETYAKELLGKT
LVTHQTGPEGKEIKRLYIEEGCAIQKEYYVGFVIDRATDQVTLMASEEGGTEIEEVAAKTPEKIFKETIDPVIGLSPFQA
RRIAFNINIPKESVNKAAKFLLALYNVFIEKDCSIVEINPLVTTADGDVLVLDAKINFDDNALFRHKDVVELRDLEEEDP
KEIEASKHDLSYIALDGDIGCMVNGAGLAMATMDTINHFGGNPANFLDAGGSATREKVTEAFKIILGDENVKGIFVNIFG
GIMKCDVIAEGIVEAVKEVDLTLPLVVRLEGTNVELGKKILKDSGLAIEPAATMAEGAQKIVKLVKEA

Sequences:

>Translated_388_residues
MNIHEYQGKEIFRSMGVAVPEGRVAFTAEEAVEKAKEFNSDVYVVKAQIHAGGRGKAGGVKIAKSLSEVETYAKELLGKT
LVTHQTGPEGKEIKRLYIEEGCAIQKEYYVGFVIDRATDQVTLMASEEGGTEIEEVAAKTPEKIFKETIDPVIGLSPFQA
RRIAFNINIPKESVNKAAKFLLALYNVFIEKDCSIVEINPLVTTADGDVLVLDAKINFDDNALFRHKDVVELRDLEEEDP
KEIEASKHDLSYIALDGDIGCMVNGAGLAMATMDTINHFGGNPANFLDAGGSATREKVTEAFKIILGDENVKGIFVNIFG
GIMKCDVIAEGIVEAVKEVDLTLPLVVRLEGTNVELGKKILKDSGLAIEPAATMAEGAQKIVKLVKEA
>Mature_388_residues
MNIHEYQGKEIFRSMGVAVPEGRVAFTAEEAVEKAKEFNSDVYVVKAQIHAGGRGKAGGVKIAKSLSEVETYAKELLGKT
LVTHQTGPEGKEIKRLYIEEGCAIQKEYYVGFVIDRATDQVTLMASEEGGTEIEEVAAKTPEKIFKETIDPVIGLSPFQA
RRIAFNINIPKESVNKAAKFLLALYNVFIEKDCSIVEINPLVTTADGDVLVLDAKINFDDNALFRHKDVVELRDLEEEDP
KEIEASKHDLSYIALDGDIGCMVNGAGLAMATMDTINHFGGNPANFLDAGGSATREKVTEAFKIILGDENVKGIFVNIFG
GIMKCDVIAEGIVEAVKEVDLTLPLVVRLEGTNVELGKKILKDSGLAIEPAATMAEGAQKIVKLVKEA

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=391, Percent_Identity=46.2915601023018, Blast_Score=350, Evalue=1e-96,
Organism=Homo sapiens, GI157779135, Length=378, Percent_Identity=47.6190476190476, Blast_Score=335, Evalue=5e-92,
Organism=Homo sapiens, GI294862256, Length=362, Percent_Identity=47.2375690607735, Blast_Score=318, Evalue=5e-87,
Organism=Escherichia coli, GI1786948, Length=386, Percent_Identity=50.5181347150259, Blast_Score=397, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI17539378, Length=391, Percent_Identity=46.2915601023018, Blast_Score=337, Evalue=8e-93,
Organism=Caenorhabditis elegans, GI17567829, Length=390, Percent_Identity=45.3846153846154, Blast_Score=326, Evalue=2e-89,
Organism=Saccharomyces cerevisiae, GI6321683, Length=396, Percent_Identity=44.1919191919192, Blast_Score=344, Evalue=2e-95,
Organism=Drosophila melanogaster, GI161078106, Length=400, Percent_Identity=44.75, Blast_Score=333, Evalue=1e-91,
Organism=Drosophila melanogaster, GI24645208, Length=400, Percent_Identity=44.75, Blast_Score=333, Evalue=1e-91,
Organism=Drosophila melanogaster, GI281361397, Length=401, Percent_Identity=44.8877805486284, Blast_Score=331, Evalue=4e-91,
Organism=Drosophila melanogaster, GI281361395, Length=401, Percent_Identity=44.8877805486284, Blast_Score=331, Evalue=4e-91,
Organism=Drosophila melanogaster, GI21356231, Length=390, Percent_Identity=44.1025641025641, Blast_Score=316, Evalue=2e-86,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 42119; Mature: 42119

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: PS50975 ATP_GRASP ; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIHEYQGKEIFRSMGVAVPEGRVAFTAEEAVEKAKEFNSDVYVVKAQIHAGGRGKAGGV
CCCCHHCHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCH
KIAKSLSEVETYAKELLGKTLVTHQTGPEGKEIKRLYIEEGCAIQKEYYVGFVIDRATDQ
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEEEEEEEEECCCCE
VTLMASEEGGTEIEEVAAKTPEKIFKETIDPVIGLSPFQARRIAFNINIPKESVNKAAKF
EEEEECCCCCCHHHHHHHCCHHHHHHHHHHHHCCCCCCCEEEEEEEECCCHHHHHHHHHH
LLALYNVFIEKDCSIVEINPLVTTADGDVLVLDAKINFDDNALFRHKDVVELRDLEEEDP
HHHHHHHHHHCCCCEEEECCEEEECCCCEEEEEEEECCCCCCEECCCCHHHHHCCCCCCC
KEIEASKHDLSYIALDGDIGCMVNGAGLAMATMDTINHFGGNPANFLDAGGSATREKVTE
HHHHCCCCCEEEEEECCCCEEEEECCCEEHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHH
AFKIILGDENVKGIFVNIFGGIMKCDVIAEGIVEAVKEVDLTLPLVVRLEGTNVELGKKI
HHHEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCHHHHHHH
LKDSGLAIEPAATMAEGAQKIVKLVKEA
HHCCCCEECCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNIHEYQGKEIFRSMGVAVPEGRVAFTAEEAVEKAKEFNSDVYVVKAQIHAGGRGKAGGV
CCCCHHCHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCH
KIAKSLSEVETYAKELLGKTLVTHQTGPEGKEIKRLYIEEGCAIQKEYYVGFVIDRATDQ
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEEEEEEEEECCCCE
VTLMASEEGGTEIEEVAAKTPEKIFKETIDPVIGLSPFQARRIAFNINIPKESVNKAAKF
EEEEECCCCCCHHHHHHHCCHHHHHHHHHHHHCCCCCCCEEEEEEEECCCHHHHHHHHHH
LLALYNVFIEKDCSIVEINPLVTTADGDVLVLDAKINFDDNALFRHKDVVELRDLEEEDP
HHHHHHHHHHCCCCEEEECCEEEECCCCEEEEEEEECCCCCCEECCCCHHHHHCCCCCCC
KEIEASKHDLSYIALDGDIGCMVNGAGLAMATMDTINHFGGNPANFLDAGGSATREKVTE
HHHHCCCCCEEEEEECCCCEEEEECCCEEHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHH
AFKIILGDENVKGIFVNIFGGIMKCDVIAEGIVEAVKEVDLTLPLVVRLEGTNVELGKKI
HHHEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCHHHHHHH
LKDSGLAIEPAATMAEGAQKIVKLVKEA
HHCCCCEECCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA