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The map label for this gene is ffh

Identifier: 82750841

GI number: 82750841

Start: 1189664

End: 1191031

Strand: Direct

Name: ffh

Synonym: SAB1101

Alternate gene names: 82750841

Gene position: 1189664-1191031 (Clockwise)

Preceding gene: 82750840

Following gene: 82750842

Centisome position: 43.38

GC content: 34.5

Gene sequence:

>1368_bases
ATGGCATTTGAAGGCTTATCAGAACGCCTGCAAGCGACGATGCAAAAAATGCGTGGTAAGGGTAAACTTACTGAAGCTGA
TATAAAGATAATGATGCGTGAAGTAAGATTAGCGTTACTTGAGGCTGACGTAAACTTTAAAGTGGTAAAAGAATTTATTA
AAACAGTATCAGAACGCGCATTAGGTTCCGATGTAATGCAATCATTAACACCAGGGCAACAAGTTATTAAAATAGTTCAA
GATGAATTAACGAAGTTGATGGGTGGAGAAAATACATCGATTAATATGTCAAATAAACCACCTACTGTTGTTATGATGGT
TGGTTTACAAGGTGCTGGTAAAACAACAACTGCAGGTAAATTAGCATTATTGATGCGTAAAAAATACAACAAAAAACCTA
TGTTAGTTGCAGCAGATATTTATCGTCCAGCAGCGATAAATCAATTACAAACAGTAGGGAAACAAATTGATATTCCTGTA
TACAGTGAAGGAGATCAGGTAAAGCCACAACAAATTGTAACTAATGCATTAAAACATGCTAAAGAAGAACATTTAGACTT
TGTAATCATTGATACAGCAGGTCGATTACACATCGATGAAGCATTGATGAACGAATTAAAAGAAGTAAAAGACATTGCTA
AACCAAACGAAATTATATTAGTTGTCGATTCAATGACGGGTCAAGATGCTGTCAATGTTGCAGAATCTTTTGACGATCAA
CTTGATGTCACAGGTGTTACCTTAACTAAATTAGATGGTGATACACGTGGTGGTGCAGCTTTATCTATTCGTTCGGTGAC
ACAAAAACCAATTAAATTTGTTGGTATGAGTGAAAAGTTAGATGGTTTAGAGCTATTCCATCCTGAACGTATGGCATCAC
GTATTTTAGGTATGGGTGATGTGTTAAGTTTAATTGAAAAAGCGCAACAAGATGTGGATCAAGAAAAAGCAAAAGATTTA
GAGAAAAAGATGCGTGAGTCATCATTTACTTTAGATGATTTTTTAGAACAACTTGATCAGGTGAAAAATTTAGGACCACT
GGATGATATTATGAAAATGATTCCAGGTATGAATAAAATGAAAGGTCTAGATAAGCTTAATATGAGTGAAAAGCAAATTG
ATCATATTAAAGCGATTATCCAGTCAATGACGCCGGCTGAAAGAAACAATCCAGACACATTGAATGTATCACGTAAAAAG
CGTATTGCTAAAGGTTCTGGTCGTTCATTACAAGAAGTCAATCGTTTGATGAAACAATTTAACGATATGAAGAAAATGAT
GAAACAATTCACTGGTGGCGGTAAAGGTAAAAAAGGTAAACGCAATCAAATGCAAAATATGTTAAAAGGTATGAATTTAC
CGTTTTAA

Upstream 100 bases:

>100_bases
GATGAAATGAAACAACATTTAAGTAATCCAGAACAAATACAACGTTATATTCAACAATTAGAAGACTTAGAATAGATATA
AATTGAGGGAGGACATCGAT

Downstream 100 bases:

>100_bases
TGTTTAATATAAACACCAATCTTTATTTCAACTTAAGGTTGGTGTTTTTGCATTAATAATATTGTAATTAAAGTTATTTA
GAGGGACATGTACAGTTGTA

Product: signal recognition particle protein

Products: NA

Alternate protein names: Fifty-four homolog [H]

Number of amino acids: Translated: 455; Mature: 454

Protein sequence:

>455_residues
MAFEGLSERLQATMQKMRGKGKLTEADIKIMMREVRLALLEADVNFKVVKEFIKTVSERALGSDVMQSLTPGQQVIKIVQ
DELTKLMGGENTSINMSNKPPTVVMMVGLQGAGKTTTAGKLALLMRKKYNKKPMLVAADIYRPAAINQLQTVGKQIDIPV
YSEGDQVKPQQIVTNALKHAKEEHLDFVIIDTAGRLHIDEALMNELKEVKDIAKPNEIILVVDSMTGQDAVNVAESFDDQ
LDVTGVTLTKLDGDTRGGAALSIRSVTQKPIKFVGMSEKLDGLELFHPERMASRILGMGDVLSLIEKAQQDVDQEKAKDL
EKKMRESSFTLDDFLEQLDQVKNLGPLDDIMKMIPGMNKMKGLDKLNMSEKQIDHIKAIIQSMTPAERNNPDTLNVSRKK
RIAKGSGRSLQEVNRLMKQFNDMKKMMKQFTGGGKGKKGKRNQMQNMLKGMNLPF

Sequences:

>Translated_455_residues
MAFEGLSERLQATMQKMRGKGKLTEADIKIMMREVRLALLEADVNFKVVKEFIKTVSERALGSDVMQSLTPGQQVIKIVQ
DELTKLMGGENTSINMSNKPPTVVMMVGLQGAGKTTTAGKLALLMRKKYNKKPMLVAADIYRPAAINQLQTVGKQIDIPV
YSEGDQVKPQQIVTNALKHAKEEHLDFVIIDTAGRLHIDEALMNELKEVKDIAKPNEIILVVDSMTGQDAVNVAESFDDQ
LDVTGVTLTKLDGDTRGGAALSIRSVTQKPIKFVGMSEKLDGLELFHPERMASRILGMGDVLSLIEKAQQDVDQEKAKDL
EKKMRESSFTLDDFLEQLDQVKNLGPLDDIMKMIPGMNKMKGLDKLNMSEKQIDHIKAIIQSMTPAERNNPDTLNVSRKK
RIAKGSGRSLQEVNRLMKQFNDMKKMMKQFTGGGKGKKGKRNQMQNMLKGMNLPF
>Mature_454_residues
AFEGLSERLQATMQKMRGKGKLTEADIKIMMREVRLALLEADVNFKVVKEFIKTVSERALGSDVMQSLTPGQQVIKIVQD
ELTKLMGGENTSINMSNKPPTVVMMVGLQGAGKTTTAGKLALLMRKKYNKKPMLVAADIYRPAAINQLQTVGKQIDIPVY
SEGDQVKPQQIVTNALKHAKEEHLDFVIIDTAGRLHIDEALMNELKEVKDIAKPNEIILVVDSMTGQDAVNVAESFDDQL
DVTGVTLTKLDGDTRGGAALSIRSVTQKPIKFVGMSEKLDGLELFHPERMASRILGMGDVLSLIEKAQQDVDQEKAKDLE
KKMRESSFTLDDFLEQLDQVKNLGPLDDIMKMIPGMNKMKGLDKLNMSEKQIDHIKAIIQSMTPAERNNPDTLNVSRKKR
IAKGSGRSLQEVNRLMKQFNDMKKMMKQFTGGGKGKKGKRNQMQNMLKGMNLPF

Specific function: Necessary for efficient export of extracytoplasmic proteins. Binds to the signal sequence when it emerges from the ribosomes [H]

COG id: COG0541

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=460, Percent_Identity=31.9565217391304, Blast_Score=231, Evalue=1e-60,
Organism=Homo sapiens, GI226371618, Length=358, Percent_Identity=34.3575418994413, Blast_Score=207, Evalue=2e-53,
Organism=Homo sapiens, GI89061728, Length=150, Percent_Identity=36.6666666666667, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI23308697, Length=300, Percent_Identity=27, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI295424842, Length=300, Percent_Identity=27, Blast_Score=92, Evalue=1e-18,
Organism=Escherichia coli, GI1788963, Length=424, Percent_Identity=51.8867924528302, Blast_Score=444, Evalue=1e-126,
Organism=Escherichia coli, GI1789874, Length=251, Percent_Identity=34.2629482071713, Blast_Score=154, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17539958, Length=461, Percent_Identity=30.58568329718, Blast_Score=229, Evalue=2e-60,
Organism=Caenorhabditis elegans, GI193206261, Length=302, Percent_Identity=29.1390728476821, Blast_Score=97, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6325345, Length=441, Percent_Identity=33.1065759637188, Blast_Score=238, Evalue=1e-63,
Organism=Saccharomyces cerevisiae, GI6320498, Length=262, Percent_Identity=27.4809160305344, Blast_Score=91, Evalue=3e-19,
Organism=Drosophila melanogaster, GI17647949, Length=444, Percent_Identity=31.7567567567568, Blast_Score=213, Evalue=2e-55,
Organism=Drosophila melanogaster, GI24641198, Length=244, Percent_Identity=26.6393442622951, Blast_Score=92, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822
- InterPro:   IPR004780
- InterPro:   IPR004125 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N; PF02978 SRP_SPB [H]

EC number: NA

Molecular weight: Translated: 50688; Mature: 50557

Theoretical pI: Translated: 10.04; Mature: 10.04

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
6.8 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
6.6 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFEGLSERLQATMQKMRGKGKLTEADIKIMMREVRLALLEADVNFKVVKEFIKTVSERA
CCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
LGSDVMQSLTPGQQVIKIVQDELTKLMGGENTSINMSNKPPTVVMMVGLQGAGKTTTAGK
HHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEEEECCCCCCCCCHHH
LALLMRKKYNKKPMLVAADIYRPAAINQLQTVGKQIDIPVYSEGDQVKPQQIVTNALKHA
HHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHCCCCEECCCCCCCHHHHHHHHHHHH
KEEHLDFVIIDTAGRLHIDEALMNELKEVKDIAKPNEIILVVDSMTGQDAVNVAESFDDQ
HHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCC
LDVTGVTLTKLDGDTRGGAALSIRSVTQKPIKFVGMSEKLDGLELFHPERMASRILGMGD
CCCCCEEEEEECCCCCCCCEEEEHHHHHHHHHHHCCCCCCCCHHHCCHHHHHHHHHCHHH
VLSLIEKAQQDVDQEKAKDLEKKMRESSFTLDDFLEQLDQVKNLGPLDDIMKMIPGMNKM
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHCCCCHHH
KGLDKLNMSEKQIDHIKAIIQSMTPAERNNPDTLNVSRKKRIAKGSGRSLQEVNRLMKQF
CCCHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHH
NDMKKMMKQFTGGGKGKKGKRNQMQNMLKGMNLPF
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
AFEGLSERLQATMQKMRGKGKLTEADIKIMMREVRLALLEADVNFKVVKEFIKTVSERA
CCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
LGSDVMQSLTPGQQVIKIVQDELTKLMGGENTSINMSNKPPTVVMMVGLQGAGKTTTAGK
HHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEEEECCCCCCCCCHHH
LALLMRKKYNKKPMLVAADIYRPAAINQLQTVGKQIDIPVYSEGDQVKPQQIVTNALKHA
HHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHCCCCEECCCCCCCHHHHHHHHHHHH
KEEHLDFVIIDTAGRLHIDEALMNELKEVKDIAKPNEIILVVDSMTGQDAVNVAESFDDQ
HHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCC
LDVTGVTLTKLDGDTRGGAALSIRSVTQKPIKFVGMSEKLDGLELFHPERMASRILGMGD
CCCCCEEEEEECCCCCCCCEEEEHHHHHHHHHHHCCCCCCCCHHHCCHHHHHHHHHCHHH
VLSLIEKAQQDVDQEKAKDLEKKMRESSFTLDDFLEQLDQVKNLGPLDDIMKMIPGMNKM
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHCCCCHHH
KGLDKLNMSEKQIDHIKAIIQSMTPAERNNPDTLNVSRKKRIAKGSGRSLQEVNRLMKQF
CCCHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHH
NDMKKMMKQFTGGGKGKKGKRNQMQNMLKGMNLPF
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8335643; 9384377; 7511896 [H]