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The map label for this gene is degP [C]

Identifier: 82750634

GI number: 82750634

Start: 963904

End: 966213

Strand: Direct

Name: degP [C]

Synonym: SAB0888

Alternate gene names: 82750634

Gene position: 963904-966213 (Clockwise)

Preceding gene: 82750633

Following gene: 82750635

Centisome position: 35.15

GC content: 31.17

Gene sequence:

>2310_bases
GTGGATATTGGTAAAAAACATGTAATTCCTAAAAGTCAGTACCGACGTAAGCGTCGTGAATTCTTCCACAACGAAGACAG
AGAAGAAAATTTAAATCAACATCAAGATAAACAAAATATAGATAATACAACATTAAAAAAAGCAGAAAAGCAAATACATA
AAGATTCAATTGATAAGCACGAACGTTTTAAAAATAGTTTATCATCGCATTTAGAACAGAGAAATCGTGATGTTAATGAG
AATAAAGCTGAAGAAAGTAAAAGTAATCAGGATAGTAAATCAGCATATAACAGAGATCATTATTTAACAGACGATGTATC
TAAAAAACAAAATTCATTAGATTCAGTGGACCAAGATACAGAGAAATCAAAATATTATGAGCAAAATTCTGAAGCGACTT
TATCAACTAAATCAACCGATAAAGTAGAATCAAGTGACATGAGAAAGCTAAGTCCAGATAAAAACAAAGTTGGTCATGAA
GAGCAACATGTACTTTCTAAACCTTCAGAACATGATAAAGAGACTAGAATTGATTTTGAGTCTTCAAGAACTGATTCAGA
CAGCTCGATGCAGACAGAGAAAATAAAAAAAGACAGTTCAGATGGAAATGAAAGTAGTAATCTGAAATCTGAAGTAATAT
CAGACAAATCAAATACAGTACCAAAATTGTCGGAATCTGATGATGAAGTAAATAATCAGAAACCATTAACTTTGCCGGAA
GAACAGAAATTGAAAAGACAACAAAGTCAAAATGAGCAAACAAAAACTTATACATATGGTGATAGCGAACAAAATGACAA
GTCTAATCATGAGAATGATTTAAGTCATCATACACCATCGAAAAGTGATGATAAAGATAACGTTATGAGAGAAGATCATA
TTGTGGACAATAATCCTGATAATGATATCAATACACCATCATTATCAAAAATAGATGACGATCGAAAACTTGATGAAAAA
ATTCATGTCGAAGATAAACATAAACAAAATGCAGACTCGTCTGAAACGGTGGGATATCAAAGTCAGTCAAGTGTATCTCA
TCGTAGCACTGAAAAAAGAAATATGGCTATTAATGACCATCATAAATTAAACGGTCAAAAACTAAATACAAAGACATCGG
CAAATAATAATCAAAAAAAGGCTACATCAAAATTGAACAAAGGGCGCGCTACAAATAATAATTATAGTGATATTTTGAAA
AAGTTTTGGATGATGTATTGGCCTAAATTAGTTATTCTAATGGGTATTATTATTCTAATTGTTATTTTGAATGCTATTTT
TAATAATGTGAACAAAAATGATCGCATGAATGATAATAATGATGCAGATGCTCAAAAATATACGACAACGATGAAAAATG
CCAATAACACAGTTAAATCGGTCGTTACAGTTGAAAATGAAACATCAAAAGATTCATCTTTACCTAAAGATAAAGCATCT
CAAGACGAAGTAGGATCAGGTGTTGTTTATAAAAAATCTGGAGATACGTTATATATTGTTACGAATGCACACGTTGTCGG
TGATAAAGAAAATCAAAAAATAACTTTCTCGAATAATAAAAGTGTTGTTGGGAAAGTGCTTGGTAAAGATAAATGGTCAG
ATTTAGCTGTTGTTAAAGCGACTTCTTCAGACAGTTCAGTGAAAGAGATAGCTATTGGAGATTCAAATAATTTAGTGTTA
GGAGAGCCAATATTAGTCGTAGGTAATCCACTTGGTGTAGACTTTAAAGGCACTGTGACAGAAGGTATTATTTCAGGTCT
GAACAGAAATGTTCTTATTGATTTCGATAAAGATAATAAATATGATATGTTGATGAAAGCTTTCCAAATTGATGCATCAG
TAAATCCAGGTAACTCGGGTGGTGCTGTCGTCAATAGAGAAGGAAAATTAATTGGTGTAGTTGCAGCTAAAATTAGTATG
CCAAACGTTGAAAATATGTCATTTGCAATACCTGTTAATGAAGTACAAAAGATTGTAAAAGATTTAGAAACAAAAGGTAA
AATTGACTATCCCGATGTAGGTGTTAAAATGAAGAATATTGCCAGTCTAAATAGTTTTGAAAGACAAGCAGTTAAATTGC
CAGGAAAAGTTAAGAACGGTGTTGTAGTAGATCAAGTTGACAACAATGGTTTAGCAGATCAATCTAGTCTGAAAAAAGGT
GATGTAATTACTGAATTAGATGGCAAACTTTTAGAAGATGATTTACGCTTTAGGCAGATTATATTTAGTCATAAAGATGA
CTTGAAATCAATTACAGCGAAGATTTATAGAGATGGTAAAGAGAAAGAAATTAATATTAAACTAAAATAA

Upstream 100 bases:

>100_bases
TATTTAGCATTTTTTCAATAGAAATTATATAGATTTTAAAGCAAATTAAGTGTTAATGTGTCATAATGAAAAGTGATTTT
ATTGAATGGAGTGGACATTA

Downstream 100 bases:

>100_bases
TGTTGAGGTGAACAACGTGTCAATTTTTAGCCAGTTTTTAAAAAGATCAAGCCCTCAACAAGGTATTGTATTGTACTATA
TCGTCGCAATTGTCGTTGCA

Product: serine proteinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 769; Mature: 769

Protein sequence:

>769_residues
MDIGKKHVIPKSQYRRKRREFFHNEDREENLNQHQDKQNIDNTTLKKAEKQIHKDSIDKHERFKNSLSSHLEQRNRDVNE
NKAEESKSNQDSKSAYNRDHYLTDDVSKKQNSLDSVDQDTEKSKYYEQNSEATLSTKSTDKVESSDMRKLSPDKNKVGHE
EQHVLSKPSEHDKETRIDFESSRTDSDSSMQTEKIKKDSSDGNESSNLKSEVISDKSNTVPKLSESDDEVNNQKPLTLPE
EQKLKRQQSQNEQTKTYTYGDSEQNDKSNHENDLSHHTPSKSDDKDNVMREDHIVDNNPDNDINTPSLSKIDDDRKLDEK
IHVEDKHKQNADSSETVGYQSQSSVSHRSTEKRNMAINDHHKLNGQKLNTKTSANNNQKKATSKLNKGRATNNNYSDILK
KFWMMYWPKLVILMGIIILIVILNAIFNNVNKNDRMNDNNDADAQKYTTTMKNANNTVKSVVTVENETSKDSSLPKDKAS
QDEVGSGVVYKKSGDTLYIVTNAHVVGDKENQKITFSNNKSVVGKVLGKDKWSDLAVVKATSSDSSVKEIAIGDSNNLVL
GEPILVVGNPLGVDFKGTVTEGIISGLNRNVLIDFDKDNKYDMLMKAFQIDASVNPGNSGGAVVNREGKLIGVVAAKISM
PNVENMSFAIPVNEVQKIVKDLETKGKIDYPDVGVKMKNIASLNSFERQAVKLPGKVKNGVVVDQVDNNGLADQSSLKKG
DVITELDGKLLEDDLRFRQIIFSHKDDLKSITAKIYRDGKEKEINIKLK

Sequences:

>Translated_769_residues
MDIGKKHVIPKSQYRRKRREFFHNEDREENLNQHQDKQNIDNTTLKKAEKQIHKDSIDKHERFKNSLSSHLEQRNRDVNE
NKAEESKSNQDSKSAYNRDHYLTDDVSKKQNSLDSVDQDTEKSKYYEQNSEATLSTKSTDKVESSDMRKLSPDKNKVGHE
EQHVLSKPSEHDKETRIDFESSRTDSDSSMQTEKIKKDSSDGNESSNLKSEVISDKSNTVPKLSESDDEVNNQKPLTLPE
EQKLKRQQSQNEQTKTYTYGDSEQNDKSNHENDLSHHTPSKSDDKDNVMREDHIVDNNPDNDINTPSLSKIDDDRKLDEK
IHVEDKHKQNADSSETVGYQSQSSVSHRSTEKRNMAINDHHKLNGQKLNTKTSANNNQKKATSKLNKGRATNNNYSDILK
KFWMMYWPKLVILMGIIILIVILNAIFNNVNKNDRMNDNNDADAQKYTTTMKNANNTVKSVVTVENETSKDSSLPKDKAS
QDEVGSGVVYKKSGDTLYIVTNAHVVGDKENQKITFSNNKSVVGKVLGKDKWSDLAVVKATSSDSSVKEIAIGDSNNLVL
GEPILVVGNPLGVDFKGTVTEGIISGLNRNVLIDFDKDNKYDMLMKAFQIDASVNPGNSGGAVVNREGKLIGVVAAKISM
PNVENMSFAIPVNEVQKIVKDLETKGKIDYPDVGVKMKNIASLNSFERQAVKLPGKVKNGVVVDQVDNNGLADQSSLKKG
DVITELDGKLLEDDLRFRQIIFSHKDDLKSITAKIYRDGKEKEINIKLK
>Mature_769_residues
MDIGKKHVIPKSQYRRKRREFFHNEDREENLNQHQDKQNIDNTTLKKAEKQIHKDSIDKHERFKNSLSSHLEQRNRDVNE
NKAEESKSNQDSKSAYNRDHYLTDDVSKKQNSLDSVDQDTEKSKYYEQNSEATLSTKSTDKVESSDMRKLSPDKNKVGHE
EQHVLSKPSEHDKETRIDFESSRTDSDSSMQTEKIKKDSSDGNESSNLKSEVISDKSNTVPKLSESDDEVNNQKPLTLPE
EQKLKRQQSQNEQTKTYTYGDSEQNDKSNHENDLSHHTPSKSDDKDNVMREDHIVDNNPDNDINTPSLSKIDDDRKLDEK
IHVEDKHKQNADSSETVGYQSQSSVSHRSTEKRNMAINDHHKLNGQKLNTKTSANNNQKKATSKLNKGRATNNNYSDILK
KFWMMYWPKLVILMGIIILIVILNAIFNNVNKNDRMNDNNDADAQKYTTTMKNANNTVKSVVTVENETSKDSSLPKDKAS
QDEVGSGVVYKKSGDTLYIVTNAHVVGDKENQKITFSNNKSVVGKVLGKDKWSDLAVVKATSSDSSVKEIAIGDSNNLVL
GEPILVVGNPLGVDFKGTVTEGIISGLNRNVLIDFDKDNKYDMLMKAFQIDASVNPGNSGGAVVNREGKLIGVVAAKISM
PNVENMSFAIPVNEVQKIVKDLETKGKIDYPDVGVKMKNIASLNSFERQAVKLPGKVKNGVVVDQVDNNGLADQSSLKKG
DVITELDGKLLEDDLRFRQIIFSHKDDLKSITAKIYRDGKEKEINIKLK

Specific function: Serine Protease That Is Required At High Temperature. Involved In The Degradation Of Damaged Proteins. It Can Degrade Icia, Ada, Casein And Globin. Shared Specificity With Degq. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Homo sapiens, GI22129776, Length=274, Percent_Identity=27.007299270073, Blast_Score=89, Evalue=2e-17,
Organism=Homo sapiens, GI4506141, Length=259, Percent_Identity=30.8880308880309, Blast_Score=83, Evalue=1e-15,
Organism=Homo sapiens, GI24308541, Length=254, Percent_Identity=31.496062992126, Blast_Score=80, Evalue=6e-15,
Organism=Homo sapiens, GI7019477, Length=260, Percent_Identity=26.5384615384615, Blast_Score=68, Evalue=4e-11,
Organism=Escherichia coli, GI1786356, Length=288, Percent_Identity=33.6805555555556, Blast_Score=122, Evalue=8e-29,
Organism=Escherichia coli, GI1789629, Length=300, Percent_Identity=31.3333333333333, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI1789630, Length=296, Percent_Identity=28.7162162162162, Blast_Score=95, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24646839, Length=260, Percent_Identity=29.6153846153846, Blast_Score=87, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 86627; Mature: 86627

Theoretical pI: Translated: 7.01; Mature: 7.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIGKKHVIPKSQYRRKRREFFHNEDREENLNQHQDKQNIDNTTLKKAEKQIHKDSIDKH
CCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
ERFKNSLSSHLEQRNRDVNENKAEESKSNQDSKSAYNRDHYLTDDVSKKQNSLDSVDQDT
HHHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHCCCCCCCCHHHHHHHHHHHHCCHH
EKSKYYEQNSEATLSTKSTDKVESSDMRKLSPDKNKVGHEEQHVLSKPSEHDKETRIDFE
HHHHHHHCCCCCEEECCCCCCCCHHHHHHCCCCHHHCCCHHHHHHCCCCCCCCHHCCCCC
SSRTDSDSSMQTEKIKKDSSDGNESSNLKSEVISDKSNTVPKLSESDDEVNNQKPLTLPE
CCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCH
EQKLKRQQSQNEQTKTYTYGDSEQNDKSNHENDLSHHTPSKSDDKDNVMREDHIVDNNPD
HHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCHHHCCCCCCCCHHHHHHHCCCCCCCCC
NDINTPSLSKIDDDRKLDEKIHVEDKHKQNADSSETVGYQSQSSVSHRSTEKRNMAINDH
CCCCCCCCCCCCCHHHHHHHCCCCHHHHCCCCCCHHCCCCCHHHHHHHHHHHHCCEECCC
HKLNGQKLNTKTSANNNQKKATSKLNKGRATNNNYSDILKKFWMMYWPKLVILMGIIILI
CCCCCCEECCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VILNAIFNNVNKNDRMNDNNDADAQKYTTTMKNANNTVKSVVTVENETSKDSSLPKDKAS
HHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCC
QDEVGSGVVYKKSGDTLYIVTNAHVVGDKENQKITFSNNKSVVGKVLGKDKWSDLAVVKA
CHHCCCCEEEEECCCEEEEEECCEEECCCCCCEEEECCCCHHHHHHHCCCCCCCEEEEEE
TSSDSSVKEIAIGDSNNLVLGEPILVVGNPLGVDFKGTVTEGIISGLNRNVLIDFDKDNK
CCCCCCCEEEEECCCCCEEECCCEEEECCCCCCCCCCHHHHHHHHCCCCCEEEEECCCCC
YDMLMKAFQIDASVNPGNSGGAVVNREGKLIGVVAAKISMPNVENMSFAIPVNEVQKIVK
HHHHHHHHHHCCCCCCCCCCCEEEECCCCEEEEEEEEECCCCCCCCEEEECHHHHHHHHH
DLETKGKIDYPDVGVKMKNIASLNSFERQAVKLPGKVKNGVVVDQVDNNGLADQSSLKKG
HHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCHHHCCCC
DVITELDGKLLEDDLRFRQIIFSHKDDLKSITAKIYRDGKEKEINIKLK
CEEEHHCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCEEEEEEC
>Mature Secondary Structure
MDIGKKHVIPKSQYRRKRREFFHNEDREENLNQHQDKQNIDNTTLKKAEKQIHKDSIDKH
CCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
ERFKNSLSSHLEQRNRDVNENKAEESKSNQDSKSAYNRDHYLTDDVSKKQNSLDSVDQDT
HHHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHCCCCCCCCHHHHHHHHHHHHCCHH
EKSKYYEQNSEATLSTKSTDKVESSDMRKLSPDKNKVGHEEQHVLSKPSEHDKETRIDFE
HHHHHHHCCCCCEEECCCCCCCCHHHHHHCCCCHHHCCCHHHHHHCCCCCCCCHHCCCCC
SSRTDSDSSMQTEKIKKDSSDGNESSNLKSEVISDKSNTVPKLSESDDEVNNQKPLTLPE
CCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCH
EQKLKRQQSQNEQTKTYTYGDSEQNDKSNHENDLSHHTPSKSDDKDNVMREDHIVDNNPD
HHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCHHHCCCCCCCCHHHHHHHCCCCCCCCC
NDINTPSLSKIDDDRKLDEKIHVEDKHKQNADSSETVGYQSQSSVSHRSTEKRNMAINDH
CCCCCCCCCCCCCHHHHHHHCCCCHHHHCCCCCCHHCCCCCHHHHHHHHHHHHCCEECCC
HKLNGQKLNTKTSANNNQKKATSKLNKGRATNNNYSDILKKFWMMYWPKLVILMGIIILI
CCCCCCEECCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VILNAIFNNVNKNDRMNDNNDADAQKYTTTMKNANNTVKSVVTVENETSKDSSLPKDKAS
HHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCC
QDEVGSGVVYKKSGDTLYIVTNAHVVGDKENQKITFSNNKSVVGKVLGKDKWSDLAVVKA
CHHCCCCEEEEECCCEEEEEECCEEECCCCCCEEEECCCCHHHHHHHCCCCCCCEEEEEE
TSSDSSVKEIAIGDSNNLVLGEPILVVGNPLGVDFKGTVTEGIISGLNRNVLIDFDKDNK
CCCCCCCEEEEECCCCCEEECCCEEEECCCCCCCCCCHHHHHHHHCCCCCEEEEECCCCC
YDMLMKAFQIDASVNPGNSGGAVVNREGKLIGVVAAKISMPNVENMSFAIPVNEVQKIVK
HHHHHHHHHHCCCCCCCCCCCEEEECCCCEEEEEEEEECCCCCCCCEEEECHHHHHHHHH
DLETKGKIDYPDVGVKMKNIASLNSFERQAVKLPGKVKNGVVVDQVDNNGLADQSSLKKG
HHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCHHHCCCC
DVITELDGKLLEDDLRFRQIIFSHKDDLKSITAKIYRDGKEKEINIKLK
CEEEHHCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Serine endopeptidases [C]

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA