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The map label for this gene is clfA

Identifier: 82750496

GI number: 82750496

Start: 817944

End: 820631

Strand: Direct

Name: clfA

Synonym: SAB0744

Alternate gene names: 82750496

Gene position: 817944-820631 (Clockwise)

Preceding gene: 82750495

Following gene: 82750497

Centisome position: 29.82

GC content: 39.25

Gene sequence:

>2688_bases
GTGGCTTCAGTGCTTGTAGGTACGTTAATCGGTTTTGGACTACTCAGCAGTAAAGAAGCAGATGCAAGTGAAAACAGTGT
TACGCAATCCGATAGCGCAAGTATTGAAATCAAAAGTAGTGATTCAAGTAGCGTTAATGTTGCACCTAAAACAGACAACA
CAAACGTGAGTGATACTAAAACAACGTCAAACACTAATAATGGCGAAACGAGTGTGGCGCAAAATCCAGCACAACAGGAA
ACGACACAATCAGCATCAACAAATGCAACTACTGAAGAAACGCCGGTAACTGGTGAAACTACTACGGCAACGAATCAAGC
TAATACACCGGCAACAACTCAATCAAGCAATACAAATGCGGAGGAATTAGTGAATCAAACAAGTAATGAAACGACTTCTA
ATGATACTAATACAGTATCATCTGTAAATTCACCTCAAAATTCTACAAATGCGGAAAATGTTTCAACAACGCAAGATACT
TCAACTGAAGCAACACCTTCAAACAATGAATCAGCTCCACAGAGTACAGATGCAAGTAATAAAGATGTAGTTAATCAAGC
GGTTAATACAAGTGCGCCTAGAATGAGAGCATTTAGTTTAGCGGCTGTAGCTGCAGATGCACCTGCAGCTGGCAAAGATA
TTACGAATCAGTTGACGAATGTGACAGTTGGTATTGACTCTGGAGATACAGTTTATCCGCACCAAGCAGGCTATGTCAAA
CTGAATTATGGGTTCTCAGTACCAAATGAGGCTGTTCAAGGTGACACATTCAAAATAACTGTGCCCAAAGAATTAAACTT
AAATGGTGTAACTTCAACTGCTAAAGTGCCACCAATTATGGCCGGAGATCAAGTATTGGCAAATGGTGTAATCGATAGTT
TTGGTAATGTTATTTATACTTTTACAGACTATGTAAATACTAAAGAAAATGTAACAGCTAATATTACTATGCCAGCTTAT
ATTGACCCTGAAAATGTTACAAAGACAGGTAATGTAACATTGGCTACTGGCATAGGTAGTACAACAGCAAACAAAACAGT
ATTAGTAGATTATGAAAAATATGGTAAGTTTTATAACTTATCTATTAAAGGTACAATTGACCAAATCGATAAAACAAATA
ATACGTATCGTCAGACAATTTATGTCAATCCAAGTGGAGATAACGTTATTGCGCCGGTTTTAACAGGTAATTTAAAACCA
AATACGGATAGTAATGCATTAATAGATCAGCAAAATACAAGTATTAAAGTATATAAAGTAGATAATGTAGCTGATTTATC
TGAAAGTTACTTTGTGAATCCAGAAAACTTTGAGGATGTCACTAATAGTGTGAATATTACATTCCCAAATCCAAATCAAT
ATAAAGTAGAGTTTAATACGCCTGATGATCAAATTACAACACCGTATATTGTAGTTGTTAATGGTCATATTGATCCGAAT
AGCAAAGGTGATTTAGCTTTACGTTCAACTTTATATGGGTATAACTCGAATATAATTTGGCGCTCTATGTCATGGGACAA
CGAAGTAGCATTTAATAACGGATCAGGTTCTGGTGACGGTATCGATAAACCAGTTGTTCCTGAACAACCTGATGAGCCTG
GTGAAATTGAACCAATTCCAGAGAATTCAGATTCTGACCCAGGTTCAGATTCTGGTAGCGATTCTAATTCAGATAGCGGT
TCAGATTCGGGTAGTGATTCTACATCAGATAGTGATTCAGATTCAGCGAGTGATTCAGATTCAGCGAGTGATTCAGATTC
AGCGAGTGATTCAGATTCAGCGAGTGATTCAGATTCAGCGAGTGATTCAGATTCAGCGAGTGATTCAGATTCAGCAAGCG
ATTCAGATTCGGATAGCGATTCCGACTCAGACAGTGACTCAGATTCGGATAGCGATTCCGACTCAGACAGTGACTCAGAT
TCGGATAGCGATTCCGACTCAGACAGTGATTCAGATTCGGATAGCGATTCCGACTCAGACAGTGACTCAGATTCGGATAG
CGATTCCGACTCAGACAGTGACTCAGATTCGGATAGCGATTCAGATTCAGCAAGCGATTCAGATTCCGATAGTGATTCAG
ATTCAGCAAGCGATTCAGATTCCGACAGTGATTCCGACTCGGACAGCGACTCAGACTCAGACAGTGACTCAGATTCCGAC
AGTGATTCAGACTCAGACAGCGATTCCGACTCAGACAGTGATTCAGATTCCGACAGTGATTCCGACTCAAATAGTGACTC
CGATTCAGACAGTGCCTCTGATTCAGCGAGTGATTCAGACTCAGGTAGTGCCTCTGATTCAGATAGTGACTCAGATTCAG
CAAGTGATTCCGACACAGATAGCGACTCAGATTCTGACAATGCTTCAGATTCCGACAGCGATTCGGATTCAGCGAGTGAT
TCCGATTCTGATTCAACGAGTGACACAGGATCAGACAATGACTCCGACTCAGAAAGTGATTCAAATAGCGATTCCGACTC
AGGTTCTAACAATAATGTAGTTCTGCCTAATTCACCTAAAAATGGTACTAATGCTTCTAATAAAAATGAAGCTAAAGATA
GTAAAGAGCCATTACCAGATACAGGTTCTGAAGGTGAAGCGAATACGTCACTAATTTGGGGATTATTAGCATCATTAGGT
TCATTACTACTTTTCAGAAGAAAAAAAGAAAATAAAGATAAGAAATAA

Upstream 100 bases:

>100_bases
TAAAGGGTATATAGTTAATATAAAATGACTTTTTAAAAAGAGGGGATAAAATGAATATGAAGAAAAAAGAAAAACACGCA
ATTCGGAAAAATCGATTGGC

Downstream 100 bases:

>100_bases
GTAATAATGATATTAAATTAATCATATGATTCATGAAGAAGCCACCTTAAAAGGTGGCTTTTTTGCTTGGATTTTCCAAA
TATATTGTTTGAATATAATT

Product: truncated clumping factor

Products: NA

Alternate protein names: Fibrinogen receptor A; Fibrinogen-binding protein A [H]

Number of amino acids: Translated: 895; Mature: 894

Protein sequence:

>895_residues
MASVLVGTLIGFGLLSSKEADASENSVTQSDSASIEIKSSDSSSVNVAPKTDNTNVSDTKTTSNTNNGETSVAQNPAQQE
TTQSASTNATTEETPVTGETTTATNQANTPATTQSSNTNAEELVNQTSNETTSNDTNTVSSVNSPQNSTNAENVSTTQDT
STEATPSNNESAPQSTDASNKDVVNQAVNTSAPRMRAFSLAAVAADAPAAGKDITNQLTNVTVGIDSGDTVYPHQAGYVK
LNYGFSVPNEAVQGDTFKITVPKELNLNGVTSTAKVPPIMAGDQVLANGVIDSFGNVIYTFTDYVNTKENVTANITMPAY
IDPENVTKTGNVTLATGIGSTTANKTVLVDYEKYGKFYNLSIKGTIDQIDKTNNTYRQTIYVNPSGDNVIAPVLTGNLKP
NTDSNALIDQQNTSIKVYKVDNVADLSESYFVNPENFEDVTNSVNITFPNPNQYKVEFNTPDDQITTPYIVVVNGHIDPN
SKGDLALRSTLYGYNSNIIWRSMSWDNEVAFNNGSGSGDGIDKPVVPEQPDEPGEIEPIPENSDSDPGSDSGSDSNSDSG
SDSGSDSTSDSDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSDSDSDSDSDSDSDSDSDSDSDSD
SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSASDSDSDSDSDSASDSDSDSDSDSDSDSDSDSDSDSD
SDSDSDSDSDSDSDSDSDSDSDSNSDSDSDSASDSASDSDSGSASDSDSDSDSASDSDTDSDSDSDNASDSDSDSDSASD
SDSDSTSDTGSDNDSDSESDSNSDSDSGSNNNVVLPNSPKNGTNASNKNEAKDSKEPLPDTGSEGEANTSLIWGLLASLG
SLLLFRRKKENKDKK

Sequences:

>Translated_895_residues
MASVLVGTLIGFGLLSSKEADASENSVTQSDSASIEIKSSDSSSVNVAPKTDNTNVSDTKTTSNTNNGETSVAQNPAQQE
TTQSASTNATTEETPVTGETTTATNQANTPATTQSSNTNAEELVNQTSNETTSNDTNTVSSVNSPQNSTNAENVSTTQDT
STEATPSNNESAPQSTDASNKDVVNQAVNTSAPRMRAFSLAAVAADAPAAGKDITNQLTNVTVGIDSGDTVYPHQAGYVK
LNYGFSVPNEAVQGDTFKITVPKELNLNGVTSTAKVPPIMAGDQVLANGVIDSFGNVIYTFTDYVNTKENVTANITMPAY
IDPENVTKTGNVTLATGIGSTTANKTVLVDYEKYGKFYNLSIKGTIDQIDKTNNTYRQTIYVNPSGDNVIAPVLTGNLKP
NTDSNALIDQQNTSIKVYKVDNVADLSESYFVNPENFEDVTNSVNITFPNPNQYKVEFNTPDDQITTPYIVVVNGHIDPN
SKGDLALRSTLYGYNSNIIWRSMSWDNEVAFNNGSGSGDGIDKPVVPEQPDEPGEIEPIPENSDSDPGSDSGSDSNSDSG
SDSGSDSTSDSDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSDSDSDSDSDSDSDSDSDSDSDSD
SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSASDSDSDSDSDSASDSDSDSDSDSDSDSDSDSDSDSD
SDSDSDSDSDSDSDSDSDSDSDSNSDSDSDSASDSASDSDSGSASDSDSDSDSASDSDTDSDSDSDNASDSDSDSDSASD
SDSDSTSDTGSDNDSDSESDSNSDSDSGSNNNVVLPNSPKNGTNASNKNEAKDSKEPLPDTGSEGEANTSLIWGLLASLG
SLLLFRRKKENKDKK
>Mature_894_residues
ASVLVGTLIGFGLLSSKEADASENSVTQSDSASIEIKSSDSSSVNVAPKTDNTNVSDTKTTSNTNNGETSVAQNPAQQET
TQSASTNATTEETPVTGETTTATNQANTPATTQSSNTNAEELVNQTSNETTSNDTNTVSSVNSPQNSTNAENVSTTQDTS
TEATPSNNESAPQSTDASNKDVVNQAVNTSAPRMRAFSLAAVAADAPAAGKDITNQLTNVTVGIDSGDTVYPHQAGYVKL
NYGFSVPNEAVQGDTFKITVPKELNLNGVTSTAKVPPIMAGDQVLANGVIDSFGNVIYTFTDYVNTKENVTANITMPAYI
DPENVTKTGNVTLATGIGSTTANKTVLVDYEKYGKFYNLSIKGTIDQIDKTNNTYRQTIYVNPSGDNVIAPVLTGNLKPN
TDSNALIDQQNTSIKVYKVDNVADLSESYFVNPENFEDVTNSVNITFPNPNQYKVEFNTPDDQITTPYIVVVNGHIDPNS
KGDLALRSTLYGYNSNIIWRSMSWDNEVAFNNGSGSGDGIDKPVVPEQPDEPGEIEPIPENSDSDPGSDSGSDSNSDSGS
DSGSDSTSDSDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSDSDSDSDSDSDSDSDSDSDSDSDS
DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSASDSDSDSDSDSASDSDSDSDSDSDSDSDSDSDSDSDS
DSDSDSDSDSDSDSDSDSDSDSNSDSDSDSASDSASDSDSGSASDSDSDSDSASDSDTDSDSDSDNASDSDSDSDSASDS
DSDSTSDTGSDNDSDSESDSNSDSDSGSNNNVVLPNSPKNGTNASNKNEAKDSKEPLPDTGSEGEANTSLIWGLLASLGS
LLLFRRKKENKDKK

Specific function: Cell surface-associated protein implicated in virulence. Promotes bacterial attachment exclusively to the gamma-chain of human fibrinogen. Induces formation of bacterial clumps [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted, cell wall; Peptidoglycan-anchor (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serine-aspartate repeat-containing protein (SDr) family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17566482, Length=234, Percent_Identity=31.1965811965812, Blast_Score=74, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011266
- InterPro:   IPR008966
- InterPro:   IPR011252
- InterPro:   IPR005877
- InterPro:   IPR019931
- InterPro:   IPR001899 [H]

Pfam domain/function: PF10425 SdrG_C_C; PF04650 YSIRK_signal [H]

EC number: NA

Molecular weight: Translated: 92693; Mature: 92562

Theoretical pI: Translated: 3.39; Mature: 3.39

Prosite motif: PS50847 GRAM_POS_ANCHORING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASVLVGTLIGFGLLSSKEADASENSVTQSDSASIEIKSSDSSSVNVAPKTDNTNVSDTK
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEECCCCCCCCCCCC
TTSNTNNGETSVAQNPAQQETTQSASTNATTEETPVTGETTTATNQANTPATTQSSNTNA
CCCCCCCCCCHHHCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
EELVNQTSNETTSNDTNTVSSVNSPQNSTNAENVSTTQDTSTEATPSNNESAPQSTDASN
HHHHHHHCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
KDVVNQAVNTSAPRMRAFSLAAVAADAPAAGKDITNQLTNVTVGIDSGDTVYPHQAGYVK
HHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHCEEEEEECCCCEECCCCCCEEE
LNYGFSVPNEAVQGDTFKITVPKELNLNGVTSTAKVPPIMAGDQVLANGVIDSFGNVIYT
EECCCCCCCHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCEEEE
FTDYVNTKENVTANITMPAYIDPENVTKTGNVTLATGIGSTTANKTVLVDYEKYGKFYNL
EEHHCCCCCCEEEEEEECCEECCCCCCCCCCEEEEECCCCCCCCCEEEEEHHHHCCEEEE
SIKGTIDQIDKTNNTYRQTIYVNPSGDNVIAPVLTGNLKPNTDSNALIDQQNTSIKVYKV
EEECCHHHHHCCCCCEEEEEEECCCCCCEEEEEEECCCCCCCCCCCEEECCCCEEEEEEC
DNVADLSESYFVNPENFEDVTNSVNITFPNPNQYKVEFNTPDDQITTPYIVVVNGHIDPN
CCHHHCCHHEECCCCCHHHHHCEEEEEECCCCEEEEEECCCCCCCCCCEEEEEECCCCCC
SKGDLALRSTLYGYNSNIIWRSMSWDNEVAFNNGSGSGDGIDKPVVPEQPDEPGEIEPIP
CCCCEEEEEEHCCCCCCEEEEECCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCC
ENSDSDPGSDSGSDSNSDSGSDSGSDSTSDSDSDSASDSDSASDSDSASDSDSASDSDSA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
SDSDSASDSDSASDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
SDSDSDSDSDSDSDSDSDSDSDSASDSDSDSDSDSASDSDSDSDSDSDSDSDSDSDSDSD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
SDSDSDSDSDSDSDSDSDSDSDSNSDSDSDSASDSASDSDSGSASDSDSDSDSASDSDTD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
SDSDSDNASDSDSDSDSASDSDSDSTSDTGSDNDSDSESDSNSDSDSGSNNNVVLPNSPK
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCC
NGTNASNKNEAKDSKEPLPDTGSEGEANTSLIWGLLASLGSLLLFRRKKENKDKK
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
ASVLVGTLIGFGLLSSKEADASENSVTQSDSASIEIKSSDSSSVNVAPKTDNTNVSDTK
CHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEECCCCCCCCCCCC
TTSNTNNGETSVAQNPAQQETTQSASTNATTEETPVTGETTTATNQANTPATTQSSNTNA
CCCCCCCCCCHHHCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
EELVNQTSNETTSNDTNTVSSVNSPQNSTNAENVSTTQDTSTEATPSNNESAPQSTDASN
HHHHHHHCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
KDVVNQAVNTSAPRMRAFSLAAVAADAPAAGKDITNQLTNVTVGIDSGDTVYPHQAGYVK
HHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHCEEEEEECCCCEECCCCCCEEE
LNYGFSVPNEAVQGDTFKITVPKELNLNGVTSTAKVPPIMAGDQVLANGVIDSFGNVIYT
EECCCCCCCHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCEEEE
FTDYVNTKENVTANITMPAYIDPENVTKTGNVTLATGIGSTTANKTVLVDYEKYGKFYNL
EEHHCCCCCCEEEEEEECCEECCCCCCCCCCEEEEECCCCCCCCCEEEEEHHHHCCEEEE
SIKGTIDQIDKTNNTYRQTIYVNPSGDNVIAPVLTGNLKPNTDSNALIDQQNTSIKVYKV
EEECCHHHHHCCCCCEEEEEEECCCCCCEEEEEEECCCCCCCCCCCEEECCCCEEEEEEC
DNVADLSESYFVNPENFEDVTNSVNITFPNPNQYKVEFNTPDDQITTPYIVVVNGHIDPN
CCHHHCCHHEECCCCCHHHHHCEEEEEECCCCEEEEEECCCCCCCCCCEEEEEECCCCCC
SKGDLALRSTLYGYNSNIIWRSMSWDNEVAFNNGSGSGDGIDKPVVPEQPDEPGEIEPIP
CCCCEEEEEEHCCCCCCEEEEECCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCC
ENSDSDPGSDSGSDSNSDSGSDSGSDSTSDSDSDSASDSDSASDSDSASDSDSASDSDSA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
SDSDSASDSDSASDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
SDSDSDSDSDSDSDSDSDSDSDSASDSDSDSDSDSASDSDSDSDSDSDSDSDSDSDSDSD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
SDSDSDSDSDSDSDSDSDSDSDSNSDSDSDSASDSASDSDSGSASDSDSDSDSASDSDTD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
SDSDSDNASDSDSDSDSASDSDSDSTSDTGSDNDSDSESDSNSDSDSGSNNNVVLPNSPK
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCC
NGTNASNKNEAKDSKEPLPDTGSEGEANTSLIWGLLASLGSLLLFRRKKENKDKK
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12044378 [H]