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The map label for this gene is ipk

Identifier: 82750202

GI number: 82750202

Start: 490926

End: 491774

Strand: Direct

Name: ipk

Synonym: SAB0444

Alternate gene names: 82750202

Gene position: 490926-491774 (Clockwise)

Preceding gene: 82750201

Following gene: 82750203

Centisome position: 17.9

GC content: 34.98

Gene sequence:

>849_bases
ATGATATATGAAACGGCACCAGCCAAAATTAATTTTACGCTCGATACACTTTTTAAAAGAAATGATGGCTATCATGAGAT
TGAAATGATAATGACAACAGTTGATTTAAATGATCGTTTAACTTTTCATAAAAGAAAAGATCGAAAGATAGTTGTTGAGA
TTGAACATAATTATGTGCCTTCTAATCATAAAAATCTCGCATATCGTGCAGCGCAACTATTTATTGAGCAATATCAACTA
AAGCAAGGTGTAACAATTTCTATCGATAAAGAAATACCTGTTTCTGCTGGCTTAGCTGGAGGTTCGGCTGATGCAGCAGC
AACGTTAAGAGGATTGAATCGACTTTTTGATATAGGGGCGAGTTTGGAAGAATTGGCTCAACTAGGCAGTAAAATCGGGA
CAGATATTCCGTTTTGTATTTATAATAAAACTGCACTATGTACTGGAAGAGGAGAGAAAATCGAGTTTTTAAATAAACCA
CCTTCAGCTTGGGTGATTCTTGCTAAACCAAACTTAGGCATATCATCACCAGATATATTTAAGTTGATCAATTTAGATAA
GCGTTACGACGTACATACGAAAATGTGTTATGAGGCCTTAGAAAATCGAGATTATCAACAATTATGTCAAAGTTTGTCTA
ATCGATTAGAGCCAATTTCTGTTTCAAAACACCCACAAATCGATAAATTGAAAAATAATATGTTGAAAAGTGGTGCAGAT
GGTGCGTTAATGAGTGGAAGCGGACCGACTGTGTATGGGCTAGCACGAAAAGAAAGCCAAGCAAAAAATATTTATAATGC
AGTTAACGGTTGTTGTAATGAAGTGTACTTAGTTAGACTATTAGGATAG

Upstream 100 bases:

>100_bases
TTTTTTATTAAAAAAACACTAAAAAACAAATTAAAATGTCAAATATTAATTCTCTTTATGTTAAAATCATCATATTAAGA
TAACGAAAAGAGGGCGGAAA

Downstream 100 bases:

>100_bases
AAGGGTTGAAAAGATGAGATATAAACGAAGCGAGAGAATTGTTTTTATGACGCAATATTTGATGAACCATCCGAATAAAT
TGATTCCATTAACTTTTTTT

Product: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase

Products: NA

Alternate protein names: CMK; 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase [H]

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MIYETAPAKINFTLDTLFKRNDGYHEIEMIMTTVDLNDRLTFHKRKDRKIVVEIEHNYVPSNHKNLAYRAAQLFIEQYQL
KQGVTISIDKEIPVSAGLAGGSADAAATLRGLNRLFDIGASLEELAQLGSKIGTDIPFCIYNKTALCTGRGEKIEFLNKP
PSAWVILAKPNLGISSPDIFKLINLDKRYDVHTKMCYEALENRDYQQLCQSLSNRLEPISVSKHPQIDKLKNNMLKSGAD
GALMSGSGPTVYGLARKESQAKNIYNAVNGCCNEVYLVRLLG

Sequences:

>Translated_282_residues
MIYETAPAKINFTLDTLFKRNDGYHEIEMIMTTVDLNDRLTFHKRKDRKIVVEIEHNYVPSNHKNLAYRAAQLFIEQYQL
KQGVTISIDKEIPVSAGLAGGSADAAATLRGLNRLFDIGASLEELAQLGSKIGTDIPFCIYNKTALCTGRGEKIEFLNKP
PSAWVILAKPNLGISSPDIFKLINLDKRYDVHTKMCYEALENRDYQQLCQSLSNRLEPISVSKHPQIDKLKNNMLKSGAD
GALMSGSGPTVYGLARKESQAKNIYNAVNGCCNEVYLVRLLG
>Mature_282_residues
MIYETAPAKINFTLDTLFKRNDGYHEIEMIMTTVDLNDRLTFHKRKDRKIVVEIEHNYVPSNHKNLAYRAAQLFIEQYQL
KQGVTISIDKEIPVSAGLAGGSADAAATLRGLNRLFDIGASLEELAQLGSKIGTDIPFCIYNKTALCTGRGEKIEFLNKP
PSAWVILAKPNLGISSPDIFKLINLDKRYDVHTKMCYEALENRDYQQLCQSLSNRLEPISVSKHPQIDKLKNNMLKSGAD
GALMSGSGPTVYGLARKESQAKNIYNAVNGCCNEVYLVRLLG

Specific function: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol [H]

COG id: COG1947

COG function: function code I; 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GHMP kinase family. IspE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787459, Length=270, Percent_Identity=30, Blast_Score=107, Evalue=9e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006204
- InterPro:   IPR013750
- InterPro:   IPR004424
- InterPro:   IPR020568
- InterPro:   IPR014721 [H]

Pfam domain/function: PF08544 GHMP_kinases_C; PF00288 GHMP_kinases_N [H]

EC number: =2.7.1.148 [H]

Molecular weight: Translated: 31458; Mature: 31458

Theoretical pI: Translated: 8.54; Mature: 8.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYETAPAKINFTLDTLFKRNDGYHEIEMIMTTVDLNDRLTFHKRKDRKIVVEIEHNYVP
CCCCCCCCEEEEEHHHHHHCCCCCEEEEEEEEEECCCCCEEEEECCCCEEEEEEECCCCC
SNHKNLAYRAAQLFIEQYQLKQGVTISIDKEIPVSAGLAGGSADAAATLRGLNRLFDIGA
CCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCC
SLEELAQLGSKIGTDIPFCIYNKTALCTGRGEKIEFLNKPPSAWVILAKPNLGISSPDIF
CHHHHHHHHHHHCCCCCEEEECCEEEECCCCCEEEECCCCCCEEEEEECCCCCCCCCCHH
KLINLDKRYDVHTKMCYEALENRDYQQLCQSLSNRLEPISVSKHPQIDKLKNNMLKSGAD
HEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCC
GALMSGSGPTVYGLARKESQAKNIYNAVNGCCNEVYLVRLLG
CCEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHEEEEEECC
>Mature Secondary Structure
MIYETAPAKINFTLDTLFKRNDGYHEIEMIMTTVDLNDRLTFHKRKDRKIVVEIEHNYVP
CCCCCCCCEEEEEHHHHHHCCCCCEEEEEEEEEECCCCCEEEEECCCCEEEEEEECCCCC
SNHKNLAYRAAQLFIEQYQLKQGVTISIDKEIPVSAGLAGGSADAAATLRGLNRLFDIGA
CCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCC
SLEELAQLGSKIGTDIPFCIYNKTALCTGRGEKIEFLNKPPSAWVILAKPNLGISSPDIF
CHHHHHHHHHHHCCCCCEEEECCEEEECCCCCEEEECCCCCCEEEEEECCCCCCCCCCHH
KLINLDKRYDVHTKMCYEALENRDYQQLCQSLSNRLEPISVSKHPQIDKLKNNMLKSGAD
HEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCC
GALMSGSGPTVYGLARKESQAKNIYNAVNGCCNEVYLVRLLG
CCEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA