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The map label for this gene is yabD [H]

Identifier: 82750198

GI number: 82750198

Start: 487873

End: 488646

Strand: Direct

Name: yabD [H]

Synonym: SAB0440

Alternate gene names: 82750198

Gene position: 487873-488646 (Clockwise)

Preceding gene: 82750197

Following gene: 82750199

Centisome position: 17.79

GC content: 36.43

Gene sequence:

>774_bases
ATGTTAATCGATACACATGTCCATTTAAATGATGAGCAATACGATGATGATTTGAGTGAAGTGATTACACGTGCTAGAGA
AGCAGGTGTTGATCGTATGTTTGTAGTTGGTTTTAACAAATCGACTATTGAACGCGCGATGAAATTAATCGATGAGTATG
ATTTTTTATATGGCATTATCGGTTGGCATCCAGTTGACGCAATTGATTTTACAGAAGAACACTTGGAATGGATTGAATCT
TTAGCTCAGCATCCAAAAGTGATTGGTATTGGTGAAATGGGATTAGATTATCACTGGGATAAATCTCCTGCAGATGTTCA
AAAGGAAGTTTTTAGAAAGCAAATCGCTTTAGCTAAGCGTTTGAAGTTACCAATTATCATTCATAACCGTGAAGCAACAC
AAGACTGTATCGATATCTTATTGGAGGAGCATGCTGAAGAGGTAGGCGGGATTATGCATAGCTTTAGTGGTTCTCCAGAA
ATTGCAGATATTGTAACTAATAAGCTGAATTTTTATATTTCATTAGGTGGACCTGTGACATTTAAAAATGCTAAACAGCC
TAAAGAAGTTGCTAAGCATGTGTCAATAGAGCGATTGCTTGTTGAAACCGATGCACCGTATCTTTCGCCACATCCGTATA
GAGGAAAGCGAAATGAACCGGCGAGAGTAACTTTAGTAGCTGAACAAATTGCTGAATTAAAAGGCTTATCTTATGAAGAA
GTGTGCGAACAAACAACTAAAAATGCAGAGAAATTGTTTAATTTAAATTCATAA

Upstream 100 bases:

>100_bases
TGAAAAAGATGGTGTATTAACATTAGTAAGTTTACCAAGTGCAATTCCGAATGGTGCAGTGATTAAATAACTGTATTTTT
GAAAATTAGGAGAGATAATT

Downstream 100 bases:

>100_bases
AGTTAAAAGTGAGAAAGATCACCGCCATAAATGTAAACGATGCTATATTCGTTTAATATGCTATGGTTCTTTCTCACTTT
TTTAAATTAAAATATCGTGC

Product: sec-independent hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MLIDTHVHLNDEQYDDDLSEVITRAREAGVDRMFVVGFNKSTIERAMKLIDEYDFLYGIIGWHPVDAIDFTEEHLEWIES
LAQHPKVIGIGEMGLDYHWDKSPADVQKEVFRKQIALAKRLKLPIIIHNREATQDCIDILLEEHAEEVGGIMHSFSGSPE
IADIVTNKLNFYISLGGPVTFKNAKQPKEVAKHVSIERLLVETDAPYLSPHPYRGKRNEPARVTLVAEQIAELKGLSYEE
VCEQTTKNAEKLFNLNS

Sequences:

>Translated_257_residues
MLIDTHVHLNDEQYDDDLSEVITRAREAGVDRMFVVGFNKSTIERAMKLIDEYDFLYGIIGWHPVDAIDFTEEHLEWIES
LAQHPKVIGIGEMGLDYHWDKSPADVQKEVFRKQIALAKRLKLPIIIHNREATQDCIDILLEEHAEEVGGIMHSFSGSPE
IADIVTNKLNFYISLGGPVTFKNAKQPKEVAKHVSIERLLVETDAPYLSPHPYRGKRNEPARVTLVAEQIAELKGLSYEE
VCEQTTKNAEKLFNLNS
>Mature_257_residues
MLIDTHVHLNDEQYDDDLSEVITRAREAGVDRMFVVGFNKSTIERAMKLIDEYDFLYGIIGWHPVDAIDFTEEHLEWIES
LAQHPKVIGIGEMGLDYHWDKSPADVQKEVFRKQIALAKRLKLPIIIHNREATQDCIDILLEEHAEEVGGIMHSFSGSPE
IADIVTNKLNFYISLGGPVTFKNAKQPKEVAKHVSIERLLVETDAPYLSPHPYRGKRNEPARVTLVAEQIAELKGLSYEE
VCEQTTKNAEKLFNLNS

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI110349730, Length=267, Percent_Identity=33.7078651685393, Blast_Score=133, Evalue=1e-31,
Organism=Homo sapiens, GI110349734, Length=267, Percent_Identity=33.7078651685393, Blast_Score=130, Evalue=9e-31,
Organism=Homo sapiens, GI226061614, Length=254, Percent_Identity=33.0708661417323, Blast_Score=129, Evalue=3e-30,
Organism=Homo sapiens, GI226061853, Length=273, Percent_Identity=33.6996336996337, Blast_Score=127, Evalue=7e-30,
Organism=Homo sapiens, GI14042943, Length=291, Percent_Identity=28.1786941580756, Blast_Score=111, Evalue=7e-25,
Organism=Homo sapiens, GI225903424, Length=220, Percent_Identity=30, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI226061595, Length=230, Percent_Identity=30.4347826086957, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI225903439, Length=248, Percent_Identity=27.4193548387097, Blast_Score=91, Evalue=7e-19,
Organism=Escherichia coli, GI1787342, Length=260, Percent_Identity=36.9230769230769, Blast_Score=172, Evalue=3e-44,
Organism=Escherichia coli, GI87082439, Length=256, Percent_Identity=30.859375, Blast_Score=131, Evalue=3e-32,
Organism=Escherichia coli, GI48994985, Length=260, Percent_Identity=29.6153846153846, Blast_Score=122, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17559024, Length=285, Percent_Identity=32.9824561403509, Blast_Score=153, Evalue=9e-38,
Organism=Caenorhabditis elegans, GI71980746, Length=264, Percent_Identity=29.1666666666667, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17565396, Length=226, Percent_Identity=31.4159292035398, Blast_Score=94, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17543026, Length=193, Percent_Identity=31.6062176165803, Blast_Score=94, Evalue=8e-20,
Organism=Drosophila melanogaster, GI24648690, Length=288, Percent_Identity=33.6805555555556, Blast_Score=135, Evalue=4e-32,
Organism=Drosophila melanogaster, GI24586117, Length=280, Percent_Identity=26.7857142857143, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI221330018, Length=280, Percent_Identity=26.7857142857143, Blast_Score=92, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 29264; Mature: 29264

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS01137 TATD_1 ; PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIDTHVHLNDEQYDDDLSEVITRAREAGVDRMFVVGFNKSTIERAMKLIDEYDFLYGII
CEEEEEEECCCHHHCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHH
GWHPVDAIDFTEEHLEWIESLAQHPKVIGIGEMGLDYHWDKSPADVQKEVFRKQIALAKR
CCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
LKLPIIIHNREATQDCIDILLEEHAEEVGGIMHSFSGSPEIADIVTNKLNFYISLGGPVT
CCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCEEEEEEECCCEE
FKNAKQPKEVAKHVSIERLLVETDAPYLSPHPYRGKRNEPARVTLVAEQIAELKGLSYEE
ECCCCCHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHCCCHHH
VCEQTTKNAEKLFNLNS
HHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLIDTHVHLNDEQYDDDLSEVITRAREAGVDRMFVVGFNKSTIERAMKLIDEYDFLYGII
CEEEEEEECCCHHHCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHH
GWHPVDAIDFTEEHLEWIESLAQHPKVIGIGEMGLDYHWDKSPADVQKEVFRKQIALAKR
CCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
LKLPIIIHNREATQDCIDILLEEHAEEVGGIMHSFSGSPEIADIVTNKLNFYISLGGPVT
CCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCEEEEEEECCCEE
FKNAKQPKEVAKHVSIERLLVETDAPYLSPHPYRGKRNEPARVTLVAEQIAELKGLSYEE
ECCCCCHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHCCCHHH
VCEQTTKNAEKLFNLNS
HHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]