Click here to switch to the map view.

The map label for this gene is yaaO [H]

Identifier: 82750188

GI number: 82750188

Start: 478882

End: 480219

Strand: Direct

Name: yaaO [H]

Synonym: SAB0430

Alternate gene names: 82750188

Gene position: 478882-480219 (Clockwise)

Preceding gene: 82750187

Following gene: 82750189

Centisome position: 17.46

GC content: 32.44

Gene sequence:

>1338_bases
ATGAAGCAACCTATTTTAAATAAATTAGAAAGTTTAAATCAAGAAGAAGCGATTTCTTTGCATGTTCCGGGTCATAAAAA
TATGACTATCGGTCATTTATCTCAATTATCAATGACAATGGATAAAACTGAAATACCTGGATTAGATGATTTACATCATC
CTGAAGAAGTCATTTTGGAAAGTATGAAGCAGGTGGAGAAACATTCAGATTATGATGGTTATTTCTTAGTGAATGGCACC
ACTTCGGGAATATTATCTGTCATCCAGTCTTTTTCACAGAAAAAAGGCGATATCTTAATGGCAAGAAATGTACATAAATC
TGTATTACATGCGCTCGATATTAGTCAGCAAGAAGGGCATTTTATTGAAACGCATCAAAGTCCGTTAACGAATCATTATA
ATAAAGTTAATTTAAGCCGTTTGAATAATGACGGTCACAAACTTGCTGTGTTAACTTATCCTAACTATTACGGTGAAACA
TTTAATGTAGAAGAGGTTATCAAATCTTTGCACCAATTAAATATTCCTGTACTCATTGACGAAGCACACGGCGCGCACTT
TGGATTGCAAGGATTTCCAGATTCTACATTAAATTATCAAGCTGACTATGTTGTTCAATCTTTTCATAAAACGTTACCAG
CTTTAACGATGGGCTCGGTACTTTATATTCATAAAAATGCACCTTATAAAGAAAATATTATAGAATATCTAAGCTATTTC
CAAACATCTAGTCCTTCATATTTGATTATGGCTAGTTTAGAGTCAGCTGCCCAGTTCTATAAAACATATGATAGTACCGT
GTTTTTTGATAAGAGAGCGCAATTAATCGAATGTTTGGAGAAGAAAGGTTTTGAAATGCTTCAGGTTGATGATCCGTTGA
AGTTGTTGATAAAATATGAAGGCTTTACAGGTCATGATATTCAAAATTGGTTTATGAATGCACATATCTATTTAGAATTA
GCTGACGACTATCAAGCATTAGCGATATTGCCGTTATGGCATCATGATGATACGTATTTATTTGATTCACTTTTACGTAA
AATTGAAGATATGATTTTACCGAAAAAATCAGTTTCTATAGTTAAACAAACACAACTTTTAACAACTGAAGGTAACTATA
AACCAAAACGCTTTGAATATGTTACTTGGTGTGATTTGAAAAAGGCAAAAGGTAAAGTTCTGGCGCGACATATTGTCCCA
TATCCGCCAGGGATTCCTATTATTTTCAAAGGAGAAACAATAACTGAAAATATGATAGAATTGGTAAATGAATATCTGGA
AACAGTAATGATAGTTGAAGGAATTAAAAATAATAAAATTTTAGTTGAGGATGAATAA

Upstream 100 bases:

>100_bases
GCATAAGTAACACTAACTTTTGTCAAAGAAGTGTTACTATATAATTAATACTTTTGAAAGTAACTAATTCAAAACATTGT
AAATAAAGGAAGCGTATATC

Downstream 100 bases:

>100_bases
AATGTCAGCTTTTATAACTTTTGAGGGCCCAGAAGGCTCAGGTAAAACAACTGTAATTAATGAAGTTTATCATAGATTAG
TAAAAGATTATGATGTCATT

Product: lysine decarboxylase

Products: 1,5-Diaminopentane; CO2 [C]

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MKQPILNKLESLNQEEAISLHVPGHKNMTIGHLSQLSMTMDKTEIPGLDDLHHPEEVILESMKQVEKHSDYDGYFLVNGT
TSGILSVIQSFSQKKGDILMARNVHKSVLHALDISQQEGHFIETHQSPLTNHYNKVNLSRLNNDGHKLAVLTYPNYYGET
FNVEEVIKSLHQLNIPVLIDEAHGAHFGLQGFPDSTLNYQADYVVQSFHKTLPALTMGSVLYIHKNAPYKENIIEYLSYF
QTSSPSYLIMASLESAAQFYKTYDSTVFFDKRAQLIECLEKKGFEMLQVDDPLKLLIKYEGFTGHDIQNWFMNAHIYLEL
ADDYQALAILPLWHHDDTYLFDSLLRKIEDMILPKKSVSIVKQTQLLTTEGNYKPKRFEYVTWCDLKKAKGKVLARHIVP
YPPGIPIIFKGETITENMIELVNEYLETVMIVEGIKNNKILVEDE

Sequences:

>Translated_445_residues
MKQPILNKLESLNQEEAISLHVPGHKNMTIGHLSQLSMTMDKTEIPGLDDLHHPEEVILESMKQVEKHSDYDGYFLVNGT
TSGILSVIQSFSQKKGDILMARNVHKSVLHALDISQQEGHFIETHQSPLTNHYNKVNLSRLNNDGHKLAVLTYPNYYGET
FNVEEVIKSLHQLNIPVLIDEAHGAHFGLQGFPDSTLNYQADYVVQSFHKTLPALTMGSVLYIHKNAPYKENIIEYLSYF
QTSSPSYLIMASLESAAQFYKTYDSTVFFDKRAQLIECLEKKGFEMLQVDDPLKLLIKYEGFTGHDIQNWFMNAHIYLEL
ADDYQALAILPLWHHDDTYLFDSLLRKIEDMILPKKSVSIVKQTQLLTTEGNYKPKRFEYVTWCDLKKAKGKVLARHIVP
YPPGIPIIFKGETITENMIELVNEYLETVMIVEGIKNNKILVEDE
>Mature_445_residues
MKQPILNKLESLNQEEAISLHVPGHKNMTIGHLSQLSMTMDKTEIPGLDDLHHPEEVILESMKQVEKHSDYDGYFLVNGT
TSGILSVIQSFSQKKGDILMARNVHKSVLHALDISQQEGHFIETHQSPLTNHYNKVNLSRLNNDGHKLAVLTYPNYYGET
FNVEEVIKSLHQLNIPVLIDEAHGAHFGLQGFPDSTLNYQADYVVQSFHKTLPALTMGSVLYIHKNAPYKENIIEYLSYF
QTSSPSYLIMASLESAAQFYKTYDSTVFFDKRAQLIECLEKKGFEMLQVDDPLKLLIKYEGFTGHDIQNWFMNAHIYLEL
ADDYQALAILPLWHHDDTYLFDSLLRKIEDMILPKKSVSIVKQTQLLTTEGNYKPKRFEYVTWCDLKKAKGKVLARHIVP
YPPGIPIIFKGETITENMIELVNEYLETVMIVEGIKNNKILVEDE

Specific function: Appears To Play A Role In pH Homeostasis By Consuming Protons And Neutralizing The Acidic By-Products Of Carbohydrate Fermentation. [C]

COG id: COG1982

COG function: function code E; Arginine/lysine/ornithine decarboxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-I family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000310
- InterPro:   IPR008286
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF01276 OKR_DC_1; PF03711 OKR_DC_1_C [H]

EC number: 4.1.1.18 [C]

Molecular weight: Translated: 51019; Mature: 51019

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQPILNKLESLNQEEAISLHVPGHKNMTIGHLSQLSMTMDKTEIPGLDDLHHPEEVILE
CCCHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHH
SMKQVEKHSDYDGYFLVNGTTSGILSVIQSFSQKKGDILMARNVHKSVLHALDISQQEGH
HHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHCCCCCCCC
FIETHQSPLTNHYNKVNLSRLNNDGHKLAVLTYPNYYGETFNVEEVIKSLHQLNIPVLID
EEECCCCCHHHCCCEEEHEEECCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCCEEEE
EAHGAHFGLQGFPDSTLNYQADYVVQSFHKTLPALTMGSVLYIHKNAPYKENIIEYLSYF
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHCCEEEEECCCCCHHHHHHHHHHH
QTSSPSYLIMASLESAAQFYKTYDSTVFFDKRAQLIECLEKKGFEMLQVDDPLKLLIKYE
HCCCCCEEEEEEHHHHHHHHHHHCCEEEEHHHHHHHHHHHHCCCEEEECCCCEEEEEEEC
GFTGHDIQNWFMNAHIYLELADDYQALAILPLWHHDDTYLFDSLLRKIEDMILPKKSVSI
CCCCCCHHHHEEEEEEEEEECCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHCCCHHHHH
VKQTQLLTTEGNYKPKRFEYVTWCDLKKAKGKVLARHIVPYPPGIPIIFKGETITENMIE
HHHHEEEEECCCCCCCCEEEEEEECCHHHCCHHHHHHCCCCCCCCCEEECCCCHHHHHHH
LVNEYLETVMIVEGIKNNKILVEDE
HHHHHHHHHHHHHCCCCCEEEEECC
>Mature Secondary Structure
MKQPILNKLESLNQEEAISLHVPGHKNMTIGHLSQLSMTMDKTEIPGLDDLHHPEEVILE
CCCHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHH
SMKQVEKHSDYDGYFLVNGTTSGILSVIQSFSQKKGDILMARNVHKSVLHALDISQQEGH
HHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHCCCCCCCC
FIETHQSPLTNHYNKVNLSRLNNDGHKLAVLTYPNYYGETFNVEEVIKSLHQLNIPVLID
EEECCCCCHHHCCCEEEHEEECCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCCEEEE
EAHGAHFGLQGFPDSTLNYQADYVVQSFHKTLPALTMGSVLYIHKNAPYKENIIEYLSYF
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHCCEEEEECCCCCHHHHHHHHHHH
QTSSPSYLIMASLESAAQFYKTYDSTVFFDKRAQLIECLEKKGFEMLQVDDPLKLLIKYE
HCCCCCEEEEEEHHHHHHHHHHHCCEEEEHHHHHHHHHHHHCCCEEEECCCCEEEEEEEC
GFTGHDIQNWFMNAHIYLELADDYQALAILPLWHHDDTYLFDSLLRKIEDMILPKKSVSI
CCCCCCHHHHEEEEEEEEEECCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHCCCHHHHH
VKQTQLLTTEGNYKPKRFEYVTWCDLKKAKGKVLARHIVPYPPGIPIIFKGETITENMIE
HHHHEEEEECCCCCCCCEEEEEEECCHHHCCHHHHHHCCCCCCCCCEEECCCCHHHHHHH
LVNEYLETVMIVEGIKNNKILVEDE
HHHHHHHHHHHHHCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal 5'-phosphate; Sulfhydryl groups [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 3.4 {S-aminoethyl-L-Cys}} 2 {L-Lys}} 1.5 {L-Lys}} 7 {delta-hydroxylysine}} [C]

Substrates: H+; L-Lysine [C]

Specific reaction: H+ + L-Lysine --> 1,5-Diaminopentane + CO2 [C]

General reaction: Decarboxylation [C]

Inhibitor: NaBH4; NaCl [C]

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]