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The map label for this gene is yhdH [H]

Identifier: 82750166

GI number: 82750166

Start: 445139

End: 446479

Strand: Direct

Name: yhdH [H]

Synonym: SAB0408

Alternate gene names: 82750166

Gene position: 445139-446479 (Clockwise)

Preceding gene: 82750165

Following gene: 82750167

Centisome position: 16.23

GC content: 34.53

Gene sequence:

>1341_bases
ATGATGAAAAGACAACAATCACAATGGAAGTCATCAACTGGATTTATTTTAGCTAGTGCGGGTTCTGCAATCGGTCTTGG
TGCCATGTGGAAATTCCCATATATGGCAGGGATCTATGGCGGCGGTGCCTTTCTAGCTATGTTCTTAATATTCACCATTT
TTGTTGGATTACCATTACTCATTATGGAATTCACTGTTGGGAAAATGGGACGGACGTATACAACACAAATATATAGTAAA
TTAACTGGTAAAAAATGGCTCAATATCATTGGTTGGAATGGTAATTTGGCAGTGTTTATTTTATTTGCCTTCTATAGTGT
TATTGGTGGTTGGATTGTCATTTACATCGGACAAGTATTATGGCAATTAGTTATATTTCAACGCATCAATCATCTCCAAG
AAATGAATTTAGAAGCGGTAATATCAAATCCTTGGTTAACCGTTCTAGGGCAAGGTATATTCATATTCGCTACGATGATT
ATTGTCATGTTAGGTGTTGAAAAAGGATTAGAAAAGGCATCGAAAGTTATGATGCCGTTGCTGTTTGTCTTTTTAATCAT
CATTGTGATTAAGTCTTTAACATTAGATGGTGCCTTAGAAGGTGTGAAATTTATTTTACAACCAAGAGTATCAGAGATTA
CTGCTGATGGAATCTTGTTTGCGCTAGGTCAATCATTCTTTACGTTATCATTAGGAACTACAGGTATGATTACTTATGCG
AGTTATGCCTCTAAAGACATGACGATTAAGTCATCAGCTATTTCTATCGTTGTTATGAATATCTTTGTATCTGTATTGGC
AGGCCTAGCTATATTTCCGGCGTTACATAGTTTTGGCTATGAACCACAAGAAGGGCCTGGATTATTATTTAAAGTACTGC
CAATGGTCTTTAGTCAAATGCATCTAGGCACATTATTCTATTTGGGATTCTTAGTGCTGTTCTTATTTGCGGCTTTAACG
TCATCTATTTCTTTATTAGAATTAAATGTTTCTAACTTCACGAAGAATGACAATACAAAACGTAAAAAAGTCGCAGTGAT
CGGTAGTATTTTAGTATTTATCATTAGTATTCCAGCAACCTTATCTTTTGGTATCTTAAAAGATGTAAGATTCGGTGCGG
GAACGATTTTTGATAATATGGATTTCATCGTTTCGAATGTATTGATGCCATTAGGCGCATTAGGTACTACGCTTGTCGTA
GGACAATTATTAGATAAAAAATTATTACAACAATATTTTGGTAAAGATCGATTTAGATTATTCAGTGGTTGGTATTACTT
AATTAAGTATGCGATGCCTGTCGTTATTATTTTAGTCTTTATCGTGCAATTATTTAGTTAA

Upstream 100 bases:

>100_bases
AATGAAACAATTTTGATGCAGGTGTATTGCATGTTATTTACATACATGTTAGAGTGTTACTTAAACACGTAGACGCTTTA
ACGCTTTAAAGGAGATGTGA

Downstream 100 bases:

>100_bases
TATATAGAAGCATCTGACGCACAAGTATTTGTGTTGCTCAGGTGTTTTTTTGTTTGGAATTGAAAAGTTTGTACTGGTTC
TGAATTAATCGAAACTTAGA

Product: sodium-dependent transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 446

Protein sequence:

>446_residues
MMKRQQSQWKSSTGFILASAGSAIGLGAMWKFPYMAGIYGGGAFLAMFLIFTIFVGLPLLIMEFTVGKMGRTYTTQIYSK
LTGKKWLNIIGWNGNLAVFILFAFYSVIGGWIVIYIGQVLWQLVIFQRINHLQEMNLEAVISNPWLTVLGQGIFIFATMI
IVMLGVEKGLEKASKVMMPLLFVFLIIIVIKSLTLDGALEGVKFILQPRVSEITADGILFALGQSFFTLSLGTTGMITYA
SYASKDMTIKSSAISIVVMNIFVSVLAGLAIFPALHSFGYEPQEGPGLLFKVLPMVFSQMHLGTLFYLGFLVLFLFAALT
SSISLLELNVSNFTKNDNTKRKKVAVIGSILVFIISIPATLSFGILKDVRFGAGTIFDNMDFIVSNVLMPLGALGTTLVV
GQLLDKKLLQQYFGKDRFRLFSGWYYLIKYAMPVVIILVFIVQLFS

Sequences:

>Translated_446_residues
MMKRQQSQWKSSTGFILASAGSAIGLGAMWKFPYMAGIYGGGAFLAMFLIFTIFVGLPLLIMEFTVGKMGRTYTTQIYSK
LTGKKWLNIIGWNGNLAVFILFAFYSVIGGWIVIYIGQVLWQLVIFQRINHLQEMNLEAVISNPWLTVLGQGIFIFATMI
IVMLGVEKGLEKASKVMMPLLFVFLIIIVIKSLTLDGALEGVKFILQPRVSEITADGILFALGQSFFTLSLGTTGMITYA
SYASKDMTIKSSAISIVVMNIFVSVLAGLAIFPALHSFGYEPQEGPGLLFKVLPMVFSQMHLGTLFYLGFLVLFLFAALT
SSISLLELNVSNFTKNDNTKRKKVAVIGSILVFIISIPATLSFGILKDVRFGAGTIFDNMDFIVSNVLMPLGALGTTLVV
GQLLDKKLLQQYFGKDRFRLFSGWYYLIKYAMPVVIILVFIVQLFS
>Mature_446_residues
MMKRQQSQWKSSTGFILASAGSAIGLGAMWKFPYMAGIYGGGAFLAMFLIFTIFVGLPLLIMEFTVGKMGRTYTTQIYSK
LTGKKWLNIIGWNGNLAVFILFAFYSVIGGWIVIYIGQVLWQLVIFQRINHLQEMNLEAVISNPWLTVLGQGIFIFATMI
IVMLGVEKGLEKASKVMMPLLFVFLIIIVIKSLTLDGALEGVKFILQPRVSEITADGILFALGQSFFTLSLGTTGMITYA
SYASKDMTIKSSAISIVVMNIFVSVLAGLAIFPALHSFGYEPQEGPGLLFKVLPMVFSQMHLGTLFYLGFLVLFLFAALT
SSISLLELNVSNFTKNDNTKRKKVAVIGSILVFIISIPATLSFGILKDVRFGAGTIFDNMDFIVSNVLMPLGALGTTLVV
GQLLDKKLLQQYFGKDRFRLFSGWYYLIKYAMPVVIILVFIVQLFS

Specific function: Putative sodium-dependent transporter [H]

COG id: COG0733

COG function: function code R; Na+-dependent transporters of the SNF family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family [H]

Homologues:

Organism=Homo sapiens, GI33354281, Length=305, Percent_Identity=27.2131147540984, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI7657587, Length=371, Percent_Identity=25.3369272237197, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI194018524, Length=297, Percent_Identity=26.9360269360269, Blast_Score=109, Evalue=5e-24,
Organism=Homo sapiens, GI51468073, Length=295, Percent_Identity=26.4406779661017, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI11181770, Length=309, Percent_Identity=26.8608414239482, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI58219014, Length=302, Percent_Identity=26.8211920529801, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI188528618, Length=366, Percent_Identity=24.8633879781421, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI134304856, Length=400, Percent_Identity=26.5, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI4507043, Length=503, Percent_Identity=22.6640159045726, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI21361581, Length=409, Percent_Identity=22.2493887530562, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI197276623, Length=352, Percent_Identity=24.1477272727273, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI54607094, Length=352, Percent_Identity=24.1477272727273, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI171184408, Length=461, Percent_Identity=22.7765726681128, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI171184406, Length=461, Percent_Identity=22.7765726681128, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI171184404, Length=461, Percent_Identity=22.7765726681128, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI289191377, Length=504, Percent_Identity=23.8095238095238, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI289191351, Length=504, Percent_Identity=23.8095238095238, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI4557046, Length=504, Percent_Identity=23.8095238095238, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI12408638, Length=291, Percent_Identity=26.1168384879725, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI4507041, Length=379, Percent_Identity=22.6912928759894, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI21361693, Length=212, Percent_Identity=25.9433962264151, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI226437581, Length=252, Percent_Identity=25, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI55749589, Length=294, Percent_Identity=23.1292517006803, Blast_Score=69, Evalue=9e-12,
Organism=Homo sapiens, GI197276625, Length=131, Percent_Identity=32.824427480916, Blast_Score=68, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI25146584, Length=419, Percent_Identity=25.2983293556086, Blast_Score=95, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17554804, Length=355, Percent_Identity=25.0704225352113, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17555248, Length=429, Percent_Identity=24.7086247086247, Blast_Score=88, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI133952791, Length=210, Percent_Identity=26.1904761904762, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI17136952, Length=379, Percent_Identity=27.4406332453826, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI281364394, Length=380, Percent_Identity=27.3684210526316, Blast_Score=118, Evalue=9e-27,
Organism=Drosophila melanogaster, GI28574704, Length=380, Percent_Identity=27.3684210526316, Blast_Score=118, Evalue=9e-27,
Organism=Drosophila melanogaster, GI17136950, Length=380, Percent_Identity=27.3684210526316, Blast_Score=118, Evalue=9e-27,
Organism=Drosophila melanogaster, GI28574702, Length=380, Percent_Identity=27.3684210526316, Blast_Score=118, Evalue=9e-27,
Organism=Drosophila melanogaster, GI24762620, Length=413, Percent_Identity=26.1501210653753, Blast_Score=115, Evalue=6e-26,
Organism=Drosophila melanogaster, GI24582567, Length=315, Percent_Identity=27.3015873015873, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24639516, Length=294, Percent_Identity=26.1904761904762, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24639514, Length=294, Percent_Identity=26.1904761904762, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI221329674, Length=293, Percent_Identity=26.2798634812287, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI45551183, Length=390, Percent_Identity=25.1282051282051, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI45550877, Length=390, Percent_Identity=25.1282051282051, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24661428, Length=364, Percent_Identity=25.2747252747253, Blast_Score=96, Evalue=7e-20,
Organism=Drosophila melanogaster, GI19921936, Length=367, Percent_Identity=25.0681198910082, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI45551088, Length=406, Percent_Identity=23.8916256157635, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24652942, Length=406, Percent_Identity=23.8916256157635, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI281364136, Length=422, Percent_Identity=22.9857819905213, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24655079, Length=300, Percent_Identity=24, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24654186, Length=175, Percent_Identity=32, Blast_Score=66, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000175 [H]

Pfam domain/function: PF00209 SNF [H]

EC number: NA

Molecular weight: Translated: 49350; Mature: 49350

Theoretical pI: Translated: 10.16; Mature: 10.16

Prosite motif: PS00610 NA_NEUROTRAN_SYMP_1 ; PS50267 NA_NEUROTRAN_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKRQQSQWKSSTGFILASAGSAIGLGAMWKFPYMAGIYGGGAFLAMFLIFTIFVGLPLL
CCCCCHHHHCCCCCEEEEECCCCCCCCHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHH
IMEFTVGKMGRTYTTQIYSKLTGKKWLNIIGWNGNLAVFILFAFYSVIGGWIVIYIGQVL
HHHHHHHHCCCHHHHHHHHHHCCHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
WQLVIFQRINHLQEMNLEAVISNPWLTVLGQGIFIFATMIIVMLGVEKGLEKASKVMMPL
HHHHHHHHHHHHHHCCHHHHCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFVFLIIIVIKSLTLDGALEGVKFILQPRVSEITADGILFALGQSFFTLSLGTTGMITYA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHEEEECCCCCHHHHH
SYASKDMTIKSSAISIVVMNIFVSVLAGLAIFPALHSFGYEPQEGPGLLFKVLPMVFSQM
HHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
HLGTLFYLGFLVLFLFAALTSSISLLELNVSNFTKNDNTKRKKVAVIGSILVFIISIPAT
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LSFGILKDVRFGAGTIFDNMDFIVSNVLMPLGALGTTLVVGQLLDKKLLQQYFGKDRFRL
HHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
FSGWYYLIKYAMPVVIILVFIVQLFS
HHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MMKRQQSQWKSSTGFILASAGSAIGLGAMWKFPYMAGIYGGGAFLAMFLIFTIFVGLPLL
CCCCCHHHHCCCCCEEEEECCCCCCCCHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHH
IMEFTVGKMGRTYTTQIYSKLTGKKWLNIIGWNGNLAVFILFAFYSVIGGWIVIYIGQVL
HHHHHHHHCCCHHHHHHHHHHCCHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
WQLVIFQRINHLQEMNLEAVISNPWLTVLGQGIFIFATMIIVMLGVEKGLEKASKVMMPL
HHHHHHHHHHHHHHCCHHHHCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFVFLIIIVIKSLTLDGALEGVKFILQPRVSEITADGILFALGQSFFTLSLGTTGMITYA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHEEEECCCCCHHHHH
SYASKDMTIKSSAISIVVMNIFVSVLAGLAIFPALHSFGYEPQEGPGLLFKVLPMVFSQM
HHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
HLGTLFYLGFLVLFLFAALTSSISLLELNVSNFTKNDNTKRKKVAVIGSILVFIISIPAT
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LSFGILKDVRFGAGTIFDNMDFIVSNVLMPLGALGTTLVVGQLLDKKLLQQYFGKDRFRL
HHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
FSGWYYLIKYAMPVVIILVFIVQLFS
HHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]