BacMap

Definition	Staphylococcus aureus RF122, complete genome.
Accession	NC_007622
Length	2,742,531

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The map label for this gene is srtF [H]

Identifier: 82750062

GI number: 82750062

Start: 349804

End: 350646

Strand: Direct

Name: srtF [H]

Synonym: SAB0301

Alternate gene names: 82750062

Gene position: 349804-350646 (Clockwise)

Preceding gene: 82750061

Following gene: 82750063

Centisome position: 12.75

GC content: 32.38

Gene sequence:

>843_bases
ATGACAACATTGTTAAACTTAGATCGTGTGAACAAACAATACAAGTCTTCGGGTTTTAAATTACAAGATGCATCTTTAAC
GATTGCTACTAATGAGACAGTTGGATTAATTGGGAAAAATGGCTCAGGTAAATCGACATTAATTAATATTCTAGTAGGCA
ATCGACATAAAGATAACGGTAGTATCACATTTTTTGGGGAAGAGTATGCTGCGGGTGATGTCGAATATAAAGAACATATA
GGTGTTGTGTTTGATGATTTGAGAGTACCTAATAAATTGACTATTAAAGATATTGATAAAATATTTCAATCTATTTATAT
GACTTGGAATAGTCAAAAATTCTTTGATTTAATCAAATATTTCGAGTTGCCACTACAAACTAAAATTAAAACTTTTTCAA
GAGGGATGCGAATGAAGATAGCTTTGACGATTGTGCTTTCTCATGATGTGAAGCTATTGATCTTAGATGAAGCAACTGCG
GGTATGGATGTTTCTGGACGAGAAGAAGTAATGGAACTATTAGAAGATTTTGTCGCGCACGGTGGAGGCATCTTAATATC
ATCGCATATTTCTGAAGATATAGAACAATTAGCGGATAAATTAGTGTTTATGAAAGATGGACGAATGATTTTAACTGAAC
AGAAAGATAGACTTTTAGCACAATATGGAATTGTTACGACAGAAGATGAAGATGTTGAAATTCCTAAGCATTTAATTATA
GCTTCTAGATTGTCAAAGGGGAAATATCAAATTTTAGTTAAAGATTATGCAGAAATTGAAAATGCAGAACCTTTAAAACA
CATTGATGACGCTACGAAAATCATAATGCGAGGTGAAGTATAA

Upstream 100 bases:

>100_bases
CAGTTTGCTACTTATCATTGCTATTTTCATATATAACGCCTTTAGTTATTTATTGAAGAGTAGACGTTTTTATTAAAATT
AAACAAAGAGGAGCAAGGAT

Downstream 100 bases:

>100_bases
TGAAAGGTATGTTCCTAAGTAGTTTTTATGCAACGAGAAAGCAAACATATATTTATTTTATAGTCGCTATCATAGCTGCG
GGATACTTTGCAGTATTTAA

Product: ABC transporter ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 280; Mature: 279

Protein sequence:

>280_residues
MTTLLNLDRVNKQYKSSGFKLQDASLTIATNETVGLIGKNGSGKSTLINILVGNRHKDNGSITFFGEEYAAGDVEYKEHI
GVVFDDLRVPNKLTIKDIDKIFQSIYMTWNSQKFFDLIKYFELPLQTKIKTFSRGMRMKIALTIVLSHDVKLLILDEATA
GMDVSGREEVMELLEDFVAHGGGILISSHISEDIEQLADKLVFMKDGRMILTEQKDRLLAQYGIVTTEDEDVEIPKHLII
ASRLSKGKYQILVKDYAEIENAEPLKHIDDATKIIMRGEV

Sequences:

>Translated_280_residues
MTTLLNLDRVNKQYKSSGFKLQDASLTIATNETVGLIGKNGSGKSTLINILVGNRHKDNGSITFFGEEYAAGDVEYKEHI
GVVFDDLRVPNKLTIKDIDKIFQSIYMTWNSQKFFDLIKYFELPLQTKIKTFSRGMRMKIALTIVLSHDVKLLILDEATA
GMDVSGREEVMELLEDFVAHGGGILISSHISEDIEQLADKLVFMKDGRMILTEQKDRLLAQYGIVTTEDEDVEIPKHLII
ASRLSKGKYQILVKDYAEIENAEPLKHIDDATKIIMRGEV
>Mature_279_residues
TTLLNLDRVNKQYKSSGFKLQDASLTIATNETVGLIGKNGSGKSTLINILVGNRHKDNGSITFFGEEYAAGDVEYKEHIG
VVFDDLRVPNKLTIKDIDKIFQSIYMTWNSQKFFDLIKYFELPLQTKIKTFSRGMRMKIALTIVLSHDVKLLILDEATAG
MDVSGREEVMELLEDFVAHGGGILISSHISEDIEQLADKLVFMKDGRMILTEQKDRLLAQYGIVTTEDEDVEIPKHLIIA
SRLSKGKYQILVKDYAEIENAEPLKHIDDATKIIMRGEV

Specific function: Implicated in the export process of the lantibiotic SrtA (Potential) [H]

COG id: COG1131

COG function: function code V; ABC-type multidrug transport system, ATPase component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI45446740, Length=212, Percent_Identity=27.3584905660377, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI47078218, Length=212, Percent_Identity=27.3584905660377, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI31657092, Length=216, Percent_Identity=24.537037037037, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI153792144, Length=221, Percent_Identity=28.9592760180996, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI27262624, Length=235, Percent_Identity=28.0851063829787, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI27262626, Length=235, Percent_Identity=28.0851063829787, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI6005701, Length=264, Percent_Identity=22.7272727272727, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI27477115, Length=209, Percent_Identity=23.9234449760766, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI255708477, Length=223, Percent_Identity=29.1479820627803, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI116734710, Length=215, Percent_Identity=25.5813953488372, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI9955963, Length=231, Percent_Identity=23.8095238095238, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1786319, Length=226, Percent_Identity=27.8761061946903, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1789891, Length=233, Percent_Identity=27.8969957081545, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1789991, Length=226, Percent_Identity=26.5486725663717, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI1788472, Length=228, Percent_Identity=26.7543859649123, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI48995001, Length=200, Percent_Identity=24, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787792, Length=221, Percent_Identity=28.9592760180996, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI48994943, Length=208, Percent_Identity=23.5576923076923, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788897, Length=214, Percent_Identity=26.1682242990654, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1790190, Length=222, Percent_Identity=24.3243243243243, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI87081782, Length=190, Percent_Identity=27.3684210526316, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1787105, Length=223, Percent_Identity=24.6636771300448, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787759, Length=212, Percent_Identity=26.4150943396226, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1788210, Length=229, Percent_Identity=26.6375545851528, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788540, Length=218, Percent_Identity=27.0642201834862, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1786654, Length=228, Percent_Identity=24.5614035087719, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790525, Length=208, Percent_Identity=24.5192307692308, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1790739, Length=201, Percent_Identity=22.8855721393035, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI48994883, Length=222, Percent_Identity=27.027027027027, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1788761, Length=224, Percent_Identity=25, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI115533608, Length=222, Percent_Identity=27.027027027027, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17510237, Length=217, Percent_Identity=26.7281105990783, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71983516, Length=232, Percent_Identity=25, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71983510, Length=232, Percent_Identity=25, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71983523, Length=232, Percent_Identity=25, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71996809, Length=245, Percent_Identity=24.4897959183673, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI212646699, Length=214, Percent_Identity=26.1682242990654, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17551700, Length=238, Percent_Identity=26.0504201680672, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI193211017, Length=245, Percent_Identity=24.4897959183673, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17551702, Length=238, Percent_Identity=26.0504201680672, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI193211015, Length=245, Percent_Identity=24.4897959183673, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24650853, Length=216, Percent_Identity=25.462962962963, Blast_Score=81, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24650855, Length=216, Percent_Identity=25.462962962963, Blast_Score=81, Evalue=6e-16,
Organism=Drosophila melanogaster, GI281362751, Length=216, Percent_Identity=25.462962962963, Blast_Score=81, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24582014, Length=232, Percent_Identity=25.4310344827586, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24582012, Length=232, Percent_Identity=25.4310344827586, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI85725262, Length=231, Percent_Identity=27.7056277056277, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI221500365, Length=222, Percent_Identity=26.1261261261261, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI116007184, Length=222, Percent_Identity=26.1261261261261, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24666092, Length=214, Percent_Identity=26.1682242990654, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28573573, Length=225, Percent_Identity=26.6666666666667, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI28573571, Length=225, Percent_Identity=26.6666666666667, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI221512771, Length=206, Percent_Identity=25.7281553398058, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI28574150, Length=206, Percent_Identity=27.1844660194175, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI116007328, Length=206, Percent_Identity=27.1844660194175, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24643674, Length=205, Percent_Identity=25.3658536585366, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24648314, Length=204, Percent_Identity=25.4901960784314, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR022501
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 31572; Mature: 31441

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTLLNLDRVNKQYKSSGFKLQDASLTIATNETVGLIGKNGSGKSTLINILVGNRHKDNG
CCCEECHHHHHHHHHHCCCEEECCEEEEEECCEEEEEECCCCCCCEEEEEEECCCCCCCC
SITFFGEEYAAGDVEYKEHIGVVFDDLRVPNKLTIKDIDKIFQSIYMTWNSQKFFDLIKY
CEEEEECCCCCCCCCHHHHCCEEEECCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHH
FELPLQTKIKTFSRGMRMKIALTIVLSHDVKLLILDEATAGMDVSGREEVMELLEDFVAH
HCCCHHHHHHHHHCCCEEEEEEEEEEECCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHC
GGGILISSHISEDIEQLADKLVFMKDGRMILTEQKDRLLAQYGIVTTEDEDVEIPKHLII
CCCEEEEHHHHHHHHHHHHHEEEEECCCEEEECHHHHHHHHHCCEECCCCCCCCCHHHHH
ASRLSKGKYQILVKDYAEIENAEPLKHIDDATKIIMRGEV
HHHCCCCCEEEEEEEHHHCCCCCCHHHHHHHHEEEEECCC
>Mature Secondary Structure 
TTLLNLDRVNKQYKSSGFKLQDASLTIATNETVGLIGKNGSGKSTLINILVGNRHKDNG
CCEECHHHHHHHHHHCCCEEECCEEEEEECCEEEEEECCCCCCCEEEEEEECCCCCCCC
SITFFGEEYAAGDVEYKEHIGVVFDDLRVPNKLTIKDIDKIFQSIYMTWNSQKFFDLIKY
CEEEEECCCCCCCCCHHHHCCEEEECCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHH
FELPLQTKIKTFSRGMRMKIALTIVLSHDVKLLILDEATAGMDVSGREEVMELLEDFVAH
HCCCHHHHHHHHHCCCEEEEEEEEEEECCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHC
GGGILISSHISEDIEQLADKLVFMKDGRMILTEQKDRLLAQYGIVTTEDEDVEIPKHLII
CCCEEEEHHHHHHHHHHHHHEEEEECCCEEEECHHHHHHHHHCCEECCCCCCCCCHHHHH
ASRLSKGKYQILVKDYAEIENAEPLKHIDDATKIIMRGEV
HHHCCCCCEEEEEEEHHHCCCCCCHHHHHHHHEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]