Click here to switch to the map view.

The map label for this gene is ubiE [H]

Identifier: 82749813

GI number: 82749813

Start: 46608

End: 47339

Strand: Direct

Name: ubiE [H]

Synonym: SAB0036

Alternate gene names: 82749813

Gene position: 46608-47339 (Clockwise)

Preceding gene: 82749812

Following gene: 82749814

Centisome position: 1.7

GC content: 34.7

Gene sequence:

>732_bases
ATGAAAAATAGAAATGATTTTATAGAAAAACTATTAGACAGAGCTCAAATTGAAGAAGGCATGCGTGTACTGGATATAGG
TTGTGCGACTGGTGAGGTCACTCAATTAATTGCAAAACGTGTGGGGGCGAATGGTGAAGTCGTCGGTGTTGATGTGAATG
AATCATTACTTAAAATTGCAAATGAAAACAATCAATATAACAATGTATCATATCAATATTCTGATATATATCAATTGCCA
GAAACTATGGGGCATTTTGATGCGATTGTTGGTAGAAGAGTATTGATGTACTTACCAGATGCTGAAAAGTGTTTACAAAC
TTTGAAATCAATTTTAAAACCTGAGGGTATATTATGTTTTCAAGAAAGTGATGCTATTAACGCAGGTATTGGTGCAGATG
CACTATCTTTACATCAATCAGCAATTCAATGGATTTGGGAAACAGTGAAGCAAGAAGGCGGCAATATTCATATCGGTCAA
AATTTATATAACTTGTTTAATAATAATGGAATGCATGTTGTAGATTATTTTGCAGAGGCAGTGATTCAAACGTCAACGGA
CAATGATTTAGCATGGCTTGTAGATATAATGCTACCAAGAATGAAAGCGCATGGTGTCATTAATGATGATTTTTCACTAG
ATGAGTTTAAATCAAACCTTGAACACGAAGCAATAAACAATCAGTGTGCATTTATACGTGACATGGCGTTTGGTATTATC
GGAAAAGCCTAG

Upstream 100 bases:

>100_bases
TGACATGCAAAGAATACAGTCGAAACCATTTTATGAGACGATTTTTAAAGAAAGAAATGTAAAATAACATACAAAAAAGT
ATATAGAGGAAGTTATGTTC

Downstream 100 bases:

>100_bases
TTTAAAAAACGCTGAAAGCAGCATGTTATCAGCGACAGTGTTTTAACTTGTGAAGTTACTAATGGATTTTGAAAATAACA
GCATTTCTATAGGCTAATCA

Product: hypothetical protein

Products: S-Adenosyl-L-Homocysteine; @OCTA02.txt*2- Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol!; Menaquinol. [C]

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MKNRNDFIEKLLDRAQIEEGMRVLDIGCATGEVTQLIAKRVGANGEVVGVDVNESLLKIANENNQYNNVSYQYSDIYQLP
ETMGHFDAIVGRRVLMYLPDAEKCLQTLKSILKPEGILCFQESDAINAGIGADALSLHQSAIQWIWETVKQEGGNIHIGQ
NLYNLFNNNGMHVVDYFAEAVIQTSTDNDLAWLVDIMLPRMKAHGVINDDFSLDEFKSNLEHEAINNQCAFIRDMAFGII
GKA

Sequences:

>Translated_243_residues
MKNRNDFIEKLLDRAQIEEGMRVLDIGCATGEVTQLIAKRVGANGEVVGVDVNESLLKIANENNQYNNVSYQYSDIYQLP
ETMGHFDAIVGRRVLMYLPDAEKCLQTLKSILKPEGILCFQESDAINAGIGADALSLHQSAIQWIWETVKQEGGNIHIGQ
NLYNLFNNNGMHVVDYFAEAVIQTSTDNDLAWLVDIMLPRMKAHGVINDDFSLDEFKSNLEHEAINNQCAFIRDMAFGII
GKA
>Mature_243_residues
MKNRNDFIEKLLDRAQIEEGMRVLDIGCATGEVTQLIAKRVGANGEVVGVDVNESLLKIANENNQYNNVSYQYSDIYQLP
ETMGHFDAIVGRRVLMYLPDAEKCLQTLKSILKPEGILCFQESDAINAGIGADALSLHQSAIQWIWETVKQEGGNIHIGQ
NLYNLFNNNGMHVVDYFAEAVIQTSTDNDLAWLVDIMLPRMKAHGVINDDFSLDEFKSNLEHEAINNQCAFIRDMAFGII
GKA

Specific function: Methyltransferase required for the conversion of dimethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) [H]

COG id: COG2226

COG function: function code H; Methylase involved in ubiquinone/menaquinone biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiE family [H]

Homologues:

Organism=Escherichia coli, GI48994983, Length=186, Percent_Identity=27.4193548387097, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004033 [H]

Pfam domain/function: PF01209 Ubie_methyltran [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 27182; Mature: 27182

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNRNDFIEKLLDRAQIEEGMRVLDIGCATGEVTQLIAKRVGANGEVVGVDVNESLLKIA
CCCHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHCCCCCEEEEECCHHHHHHH
NENNQYNNVSYQYSDIYQLPETMGHFDAIVGRRVLMYLPDAEKCLQTLKSILKPEGILCF
CCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHCCCCEEEE
QESDAINAGIGADALSLHQSAIQWIWETVKQEGGNIHIGQNLYNLFNNNGMHVVDYFAEA
ECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECHHHHHHHCCCCCHHHHHHHHH
VIQTSTDNDLAWLVDIMLPRMKAHGVINDDFSLDEFKSNLEHEAINNQCAFIRDMAFGII
HHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHH
GKA
CCC
>Mature Secondary Structure
MKNRNDFIEKLLDRAQIEEGMRVLDIGCATGEVTQLIAKRVGANGEVVGVDVNESLLKIA
CCCHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHCCCCCEEEEECCHHHHHHH
NENNQYNNVSYQYSDIYQLPETMGHFDAIVGRRVLMYLPDAEKCLQTLKSILKPEGILCF
CCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHCCCCEEEE
QESDAINAGIGADALSLHQSAIQWIWETVKQEGGNIHIGQNLYNLFNNNGMHVVDYFAEA
ECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECHHHHHHHCCCCCHHHHHHHHH
VIQTSTDNDLAWLVDIMLPRMKAHGVINDDFSLDEFKSNLEHEAINNQCAFIRDMAFGII
HHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHH
GKA
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; 2-Polyprenyl-6- Methoxy-1,4-Benzoquinol; Demethylmenaquinol [C]

Specific reaction: S-Adenosyl-L-Methionine + @OCTA02.txt*2-Polyprenyl-6- Methoxy-1,4-Benzoquinol! = S-Adenosyl-L-Homocysteine + 2- Polyprenyl-3-Methyl-6-Methoxy -1,4-Benzoquinol S-Adenosyl-L-Methionine + Demethylmenaquinol = S-Adenosyl-L-Homocysteine + Menaquinol. [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA