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The map label for this gene is mlaC [H]

Identifier: 82703859

GI number: 82703859

Start: 3149655

End: 3150311

Strand: Reverse

Name: mlaC [H]

Synonym: Nmul_A2746

Alternate gene names: 82703859

Gene position: 3150311-3149655 (Counterclockwise)

Preceding gene: 82703860

Following gene: 82703858

Centisome position: 98.93

GC content: 52.82

Gene sequence:

>657_bases
ATGAAAAAATATCTTGGTATCTCAGGTCTGCTGGCAACCTGGCTGGTCGCATTCCCTGCTGCCGCCGCAGAAATCAGTCC
TGATACGCTGGTGGATAACACCGCTCAGGAAGTATTGTCGATCGTTCGGCAGGACAAGGAGCTGCGTGCGGGCAATATGG
CCAAGATTCTTGATCTGGTCGAAGCCAAGGTTCTACCGCATTTCAACTTCACCCGCATGACCCGACTCGCCATGGGCAAG
AACTGGAATAAGGCAACCCCACAGCAACAGGAGGAATTGGTGAAAGAGTTCCGTACGTTGCTAGTGAGGACTTACTCCAA
TGCCCTCAGTACCTACAGTGACTACAAGATCAAGGTTGAGCCGGTCAGGAGCAAGGCAGAGGACACGGATACCACCGTCA
AAACCAAAGTCATGCAGGATAGCGGGCAACCCGTGGATATCGACTACAGCATGGAAAAAACAGGGGACGGGTGGAAAGTC
TACGATGTGACAGTGGCAGGCGTAAGCCTCGTCACGAATTACCGCAGCACGTTCAATAGCCAGGTGCGTGAAGGCGGTGT
GGAAAAATTACTGAAAACCCTCGGGGACAAGAACCGTGCGCTGGCCGCTAACGATAAAAAAGCAGCCGGCGAATTAAAGA
CGGTAGCCACGCAGTAG

Upstream 100 bases:

>100_bases
AGGGCCTGCGGGCAGGAAGCAGGAGCAGTTGATGCGGGCACGGGAAGCGCAACCGCATAAGCATTTCGTGTATTGAGCAG
TCTAATCAAGCGAGGAAATC

Downstream 100 bases:

>100_bases
CCGATGACCACTATCGTCCGGCGTGAGGGCGGGGAACTCAGCGTCGAAGGATCGATTACGATCGATAACGTCGTTTCGGT
GGTTGCGAACGGTGTGGCTT

Product: toluene tolerance

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 218; Mature: 218

Protein sequence:

>218_residues
MKKYLGISGLLATWLVAFPAAAAEISPDTLVDNTAQEVLSIVRQDKELRAGNMAKILDLVEAKVLPHFNFTRMTRLAMGK
NWNKATPQQQEELVKEFRTLLVRTYSNALSTYSDYKIKVEPVRSKAEDTDTTVKTKVMQDSGQPVDIDYSMEKTGDGWKV
YDVTVAGVSLVTNYRSTFNSQVREGGVEKLLKTLGDKNRALAANDKKAAGELKTVATQ

Sequences:

>Translated_218_residues
MKKYLGISGLLATWLVAFPAAAAEISPDTLVDNTAQEVLSIVRQDKELRAGNMAKILDLVEAKVLPHFNFTRMTRLAMGK
NWNKATPQQQEELVKEFRTLLVRTYSNALSTYSDYKIKVEPVRSKAEDTDTTVKTKVMQDSGQPVDIDYSMEKTGDGWKV
YDVTVAGVSLVTNYRSTFNSQVREGGVEKLLKTLGDKNRALAANDKKAAGELKTVATQ
>Mature_218_residues
MKKYLGISGLLATWLVAFPAAAAEISPDTLVDNTAQEVLSIVRQDKELRAGNMAKILDLVEAKVLPHFNFTRMTRLAMGK
NWNKATPQQQEELVKEFRTLLVRTYSNALSTYSDYKIKVEPVRSKAEDTDTTVKTKVMQDSGQPVDIDYSMEKTGDGWKV
YDVTVAGVSLVTNYRSTFNSQVREGGVEKLLKTLGDKNRALAANDKKAAGELKTVATQ

Specific function: Actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. May transfer phospholipid across the peripl

COG id: COG2854

COG function: function code Q; ABC-type transport system involved in resistance to organic solvents, auxiliary component

Gene ontology:

Cell location: Periplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mlaC/ttg2D family [H]

Homologues:

Organism=Escherichia coli, GI1789583, Length=198, Percent_Identity=25.2525252525253, Blast_Score=78, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023094
- InterPro:   IPR008869 [H]

Pfam domain/function: PF05494 Tol_Tol_Ttg2 [H]

EC number: NA

Molecular weight: Translated: 24181; Mature: 24181

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKYLGISGLLATWLVAFPAAAAEISPDTLVDNTAQEVLSIVRQDKELRAGNMAKILDLV
CCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
EAKVLPHFNFTRMTRLAMGKNWNKATPQQQEELVKEFRTLLVRTYSNALSTYSDYKIKVE
HHHHCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
PVRSKAEDTDTTVKTKVMQDSGQPVDIDYSMEKTGDGWKVYDVTVAGVSLVTNYRSTFNS
ECCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHH
QVREGGVEKLLKTLGDKNRALAANDKKAAGELKTVATQ
HHHHCHHHHHHHHHCCCCCEECCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MKKYLGISGLLATWLVAFPAAAAEISPDTLVDNTAQEVLSIVRQDKELRAGNMAKILDLV
CCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
EAKVLPHFNFTRMTRLAMGKNWNKATPQQQEELVKEFRTLLVRTYSNALSTYSDYKIKVE
HHHHCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
PVRSKAEDTDTTVKTKVMQDSGQPVDIDYSMEKTGDGWKVYDVTVAGVSLVTNYRSTFNS
ECCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHH
QVREGGVEKLLKTLGDKNRALAANDKKAAGELKTVATQ
HHHHCHHHHHHHHHCCCCCEECCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]