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The map label for this gene is coaD

Identifier: 82703847

GI number: 82703847

Start: 3139627

End: 3140124

Strand: Reverse

Name: coaD

Synonym: Nmul_A2734

Alternate gene names: 82703847

Gene position: 3140124-3139627 (Counterclockwise)

Preceding gene: 82703848

Following gene: 82703846

Centisome position: 98.61

GC content: 51.81

Gene sequence:

>498_bases
ATGGATAAAGCGATATACCCCGGTACTTTCGATCCCATTACGCGGGGTCATGAAGATCTGGTGCGACGTGCCTCCGGTTT
GTTCAGGGAGGTGGTGGTAGCGGTCGCTGCAAGCAGCGGAAAAAAACCGTTCTTTACCCAGGAGGAGCGGGTGGCGATGG
TGCGTCAGGTGCTGACGGATTATCCCAACGTTAAAGTCATGCCGTTTTCAGGCTTGCTGATGGAGTTCGCGCAACAACAG
CAGGCGAGGGTAATCGTGCGCGGTTTGCGAGCTGTGTCGGATTTCGAATATGAATTCCAGATGGCAGGAATGAATCGTAC
GCTTTATCCGGATGTCGAGACTTTGTTTCTTACGCCCTCCGAGCAATATATGTTTATATCCGCCACGATCGTGCGCGAAA
TCGCCTTGTTCGGCGGCAATATAGAAAAGTTCGTGCACCCCCTTATTTCGACGCAACTTGGAATGAAGATCGCGTCGAAG
GACAAATCATCGAGGTAG

Upstream 100 bases:

>100_bases
GGAAGACGATTGCCCCGCGGAGTTTGAAGGATGGGCAGTGTGGCGCAGGGGACATGCAGGAAAGGTGTGCTATCACTTGT
TAAGCTCCACGATAAATTAA

Downstream 100 bases:

>100_bases
CCATGGCTTTAATGATCACCGATGAATGCATCAATTGCGACGTGTGCCAGCCAGAGTGCCCGAACAGCGCCATTTCGCCC
GGCGAGGAGTACTATGAAAT

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 165; Mature: 165

Protein sequence:

>165_residues
MDKAIYPGTFDPITRGHEDLVRRASGLFREVVVAVAASSGKKPFFTQEERVAMVRQVLTDYPNVKVMPFSGLLMEFAQQQ
QARVIVRGLRAVSDFEYEFQMAGMNRTLYPDVETLFLTPSEQYMFISATIVREIALFGGNIEKFVHPLISTQLGMKIASK
DKSSR

Sequences:

>Translated_165_residues
MDKAIYPGTFDPITRGHEDLVRRASGLFREVVVAVAASSGKKPFFTQEERVAMVRQVLTDYPNVKVMPFSGLLMEFAQQQ
QARVIVRGLRAVSDFEYEFQMAGMNRTLYPDVETLFLTPSEQYMFISATIVREIALFGGNIEKFVHPLISTQLGMKIASK
DKSSR
>Mature_165_residues
MDKAIYPGTFDPITRGHEDLVRRASGLFREVVVAVAASSGKKPFFTQEERVAMVRQVLTDYPNVKVMPFSGLLMEFAQQQ
QARVIVRGLRAVSDFEYEFQMAGMNRTLYPDVETLFLTPSEQYMFISATIVREIALFGGNIEKFVHPLISTQLGMKIASK
DKSSR

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=156, Percent_Identity=50.6410256410256, Blast_Score=170, Evalue=4e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_NITMU (Q2Y5F0)

Other databases:

- EMBL:   CP000103
- RefSeq:   YP_413413.1
- HSSP:   Q9WZK0
- ProteinModelPortal:   Q2Y5F0
- SMR:   Q2Y5F0
- STRING:   Q2Y5F0
- GeneID:   3785705
- GenomeReviews:   CP000103_GR
- KEGG:   nmu:Nmul_A2734
- eggNOG:   COG0669
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- PhylomeDB:   Q2Y5F0
- ProtClustDB:   PRK00168
- BioCyc:   NMUL323848:NMUL_A2734-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 18647; Mature: 18647

Theoretical pI: Translated: 9.40; Mature: 9.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKAIYPGTFDPITRGHEDLVRRASGLFREVVVAVAASSGKKPFFTQEERVAMVRQVLTD
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHC
YPNVKVMPFSGLLMEFAQQQQARVIVRGLRAVSDFEYEFQMAGMNRTLYPDVETLFLTPS
CCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCEEEEECCC
EQYMFISATIVREIALFGGNIEKFVHPLISTQLGMKIASKDKSSR
CCEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHCCCCCCC
>Mature Secondary Structure
MDKAIYPGTFDPITRGHEDLVRRASGLFREVVVAVAASSGKKPFFTQEERVAMVRQVLTD
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHC
YPNVKVMPFSGLLMEFAQQQQARVIVRGLRAVSDFEYEFQMAGMNRTLYPDVETLFLTPS
CCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCEEEEECCC
EQYMFISATIVREIALFGGNIEKFVHPLISTQLGMKIASKDKSSR
CCEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA