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The map label for this gene is queC

Identifier: 82703823

GI number: 82703823

Start: 3112176

End: 3112874

Strand: Reverse

Name: queC

Synonym: Nmul_A2710

Alternate gene names: 82703823

Gene position: 3112874-3112176 (Counterclockwise)

Preceding gene: 82703824

Following gene: 82703822

Centisome position: 97.76

GC content: 57.65

Gene sequence:

>699_bases
ATGGTTAAGGCAGTCGTGCTGCTGTCAGGAGGTCTGGACTCGGCCACCGTCCTTGCTATCGCCCGCCAGCAAGGATATGA
GTGTTATGCCTTGAGCGTGAGCTACGGCCAGCGCCACGGCGCGGAGCTCGCCGCGGCAAAAAATCTTGCCCGCTCCTTGG
GTGCCACCGCCCATAAAATCATTCAAGTGGATCTTTCCACATTCGGGGGCTCCGCGCTTATCGACAAAGAGCGTGAAATT
CCGACGGACGGGGTTACGCCGGGCATTCCCAGCACCTACGTACCCGCGCGTAATACCATCATGCTTTCCATTGCACTGGC
CTGGGCCGAAGTGCTGGGGAGCGGGGATATTTTCATCGGTGTTAACGCAATTGACTATTCTGGTTATCCCGATTGCCGTC
CTGAGTATATCGAAGCCTTTGAGACGATGGCGAACGTCGCGACAAAAGCCGGGATTGAAGGGACACGCCTTGCCATTCAC
GCGCCTCTAATGAATTTGTCGAAGGCGGAGATCATAAAGAGGGGGGGCGTGCTCGGCGTTGACTACAGCATGACTGTTTC
CTGCTATCAGGCGGACGATGCGGGGCTGGCCTGCGGCGTATGTGATTCCTGCCGCTTGCGACGGGCGGGCTTTGAATCGG
CAGATGTTCCCGACGTAACGCGTTATCACGCAGGTTTCCGGCAGACGCCTGCTTCCTGA

Upstream 100 bases:

>100_bases
AGGTTCAGTTGCACAAATTGCTGTGGGGGGAGGGCCCCGGACGATAACGGGTGCTAACGGGGTAAAATAGACCGCGTCGT
GACTCGTTTTTTACAACTTT

Downstream 100 bases:

>100_bases
TACTCAAACAGAAGGTACTCAACGCCTTGCTGGTTTCATGATTCCCTGGCTCTCGTCTGATTCCCTCTTCCCTCCGCTGC
ACACCGCGCTCATTCAGCCA

Product: ExsB

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MVKAVVLLSGGLDSATVLAIARQQGYECYALSVSYGQRHGAELAAAKNLARSLGATAHKIIQVDLSTFGGSALIDKEREI
PTDGVTPGIPSTYVPARNTIMLSIALAWAEVLGSGDIFIGVNAIDYSGYPDCRPEYIEAFETMANVATKAGIEGTRLAIH
APLMNLSKAEIIKRGGVLGVDYSMTVSCYQADDAGLACGVCDSCRLRRAGFESADVPDVTRYHAGFRQTPAS

Sequences:

>Translated_232_residues
MVKAVVLLSGGLDSATVLAIARQQGYECYALSVSYGQRHGAELAAAKNLARSLGATAHKIIQVDLSTFGGSALIDKEREI
PTDGVTPGIPSTYVPARNTIMLSIALAWAEVLGSGDIFIGVNAIDYSGYPDCRPEYIEAFETMANVATKAGIEGTRLAIH
APLMNLSKAEIIKRGGVLGVDYSMTVSCYQADDAGLACGVCDSCRLRRAGFESADVPDVTRYHAGFRQTPAS
>Mature_232_residues
MVKAVVLLSGGLDSATVLAIARQQGYECYALSVSYGQRHGAELAAAKNLARSLGATAHKIIQVDLSTFGGSALIDKEREI
PTDGVTPGIPSTYVPARNTIMLSIALAWAEVLGSGDIFIGVNAIDYSGYPDCRPEYIEAFETMANVATKAGIEGTRLAIH
APLMNLSKAEIIKRGGVLGVDYSMTVSCYQADDAGLACGVCDSCRLRRAGFESADVPDVTRYHAGFRQTPAS

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family

Homologues:

Organism=Escherichia coli, GI1786648, Length=227, Percent_Identity=37.4449339207048, Blast_Score=129, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QUEC_NITMU (Q2Y5H4)

Other databases:

- EMBL:   CP000103
- RefSeq:   YP_413389.1
- ProteinModelPortal:   Q2Y5H4
- SMR:   Q2Y5H4
- STRING:   Q2Y5H4
- GeneID:   3786127
- GenomeReviews:   CP000103_GR
- KEGG:   nmu:Nmul_A2710
- eggNOG:   COG0603
- HOGENOM:   HBG553284
- OMA:   GWAEVLG
- PhylomeDB:   Q2Y5H4
- BioCyc:   NMUL323848:NMUL_A2710-MONOMER
- HAMAP:   MF_01633_B
- InterPro:   IPR018317
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PIRSF:   PIRSF006293
- TIGRFAMs:   TIGR00364

Pfam domain/function: PF06508 ExsB

EC number: NA

Molecular weight: Translated: 24480; Mature: 24480

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKAVVLLSGGLDSATVLAIARQQGYECYALSVSYGQRHGAELAAAKNLARSLGATAHKI
CEEEEEEEECCCCCHHHEEEHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCEEE
IQVDLSTFGGSALIDKEREIPTDGVTPGIPSTYVPARNTIMLSIALAWAEVLGSGDIFIG
EEEEHHHCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHCCCCEEEE
VNAIDYSGYPDCRPEYIEAFETMANVATKAGIEGTRLAIHAPLMNLSKAEIIKRGGVLGV
EEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHCCCEEEE
DYSMTVSCYQADDAGLACGVCDSCRLRRAGFESADVPDVTRYHAGFRQTPAS
CCEEEEEEEECCCCCEEECCCHHHHHHHCCCCCCCCCCHHHHHCCCCCCCCC
>Mature Secondary Structure
MVKAVVLLSGGLDSATVLAIARQQGYECYALSVSYGQRHGAELAAAKNLARSLGATAHKI
CEEEEEEEECCCCCHHHEEEHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCEEE
IQVDLSTFGGSALIDKEREIPTDGVTPGIPSTYVPARNTIMLSIALAWAEVLGSGDIFIG
EEEEHHHCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHCCCCEEEE
VNAIDYSGYPDCRPEYIEAFETMANVATKAGIEGTRLAIHAPLMNLSKAEIIKRGGVLGV
EEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHCCCEEEE
DYSMTVSCYQADDAGLACGVCDSCRLRRAGFESADVPDVTRYHAGFRQTPAS
CCEEEEEEEECCCCCEEECCCHHHHHHHCCCCCCCCCCHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA